BRPI0410031A - variantes fc otimizadas e métodos para sua geração - Google Patents

variantes fc otimizadas e métodos para sua geração

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Publication number
BRPI0410031A
BRPI0410031A BRPI0410031-0A BRPI0410031A BRPI0410031A BR PI0410031 A BRPI0410031 A BR PI0410031A BR PI0410031 A BRPI0410031 A BR PI0410031A BR PI0410031 A BRPI0410031 A BR PI0410031A
Authority
BR
Brazil
Prior art keywords
optimized
variants
generation
methods
fusions
Prior art date
Application number
BRPI0410031-0A
Other languages
English (en)
Inventor
Gregory Alan Lazar
Arthur Chirino
Wei Dang
John Rudolph Desjarlais
Robert J Hayes
Sher Bahadur Karki
Stephen Kohl Doberstein
Omid Vafa
Original Assignee
Xencor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33437072&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0410031(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xencor Inc filed Critical Xencor Inc
Priority to BR122018016045A priority Critical patent/BR122018016045B8/pt
Publication of BRPI0410031A publication Critical patent/BRPI0410031A/pt

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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K16/2875Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/4283Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
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Abstract

"VARIANTES Fc OTIMIZADAS E MéTODOS PARA SUA GERAçãO". A presente invenção se relaciona a variantes Fc otimizadas, métodos para sua geração e anticorpos e fusões Fc que compreendem as variantes Fc otimizadas.
BRPI0410031-0A 2003-05-02 2004-03-26 variantes fc otimizadas e métodos para sua geração BRPI0410031A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122018016045A BR122018016045B8 (pt) 2003-05-02 2004-03-26 proteína variante otimizada

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46760603P 2003-05-02 2003-05-02
US47783903P 2003-06-12 2003-06-12
US10/672,280 US20040132101A1 (en) 2002-09-27 2003-09-26 Optimized Fc variants and methods for their generation
PCT/US2004/009298 WO2004099249A2 (en) 2003-05-02 2004-03-26 Optimized fc variants and methods for their generation

Publications (1)

Publication Number Publication Date
BRPI0410031A true BRPI0410031A (pt) 2006-04-25

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Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0410031-0A BRPI0410031A (pt) 2003-05-02 2004-03-26 variantes fc otimizadas e métodos para sua geração
BR122018016045A BR122018016045B8 (pt) 2003-05-02 2004-03-26 proteína variante otimizada

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BR122018016045A BR122018016045B8 (pt) 2003-05-02 2004-03-26 proteína variante otimizada

Country Status (15)

Country Link
US (12) US20040132101A1 (pt)
EP (4) EP3838920A1 (pt)
JP (1) JP4578467B2 (pt)
KR (2) KR100890586B1 (pt)
CN (3) CN104788565A (pt)
AU (2) AU2004236160B2 (pt)
BR (2) BRPI0410031A (pt)
CA (2) CA2524399C (pt)
DK (1) DK2368911T3 (pt)
ES (1) ES2638568T3 (pt)
HU (1) HUE034268T2 (pt)
IL (3) IL171723A (pt)
PL (1) PL2368911T4 (pt)
SI (1) SI2368911T1 (pt)
WO (1) WO2004099249A2 (pt)

Families Citing this family (751)

* Cited by examiner, † Cited by third party
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