BRPI0413728B8 - muteína da lipocalina da lágrima humana, métodos para geração e para produção de muteína, composição farmacêutica e uso de muteína - Google Patents

muteína da lipocalina da lágrima humana, métodos para geração e para produção de muteína, composição farmacêutica e uso de muteína

Info

Publication number
BRPI0413728B8
BRPI0413728B8 BRPI0413728A BRPI0413728A BRPI0413728B8 BR PI0413728 B8 BRPI0413728 B8 BR PI0413728B8 BR PI0413728 A BRPI0413728 A BR PI0413728A BR PI0413728 A BRPI0413728 A BR PI0413728A BR PI0413728 B8 BRPI0413728 B8 BR PI0413728B8
Authority
BR
Brazil
Prior art keywords
mutein
pharmaceutical composition
producing
tear lipocalin
generating
Prior art date
Application number
BRPI0413728A
Other languages
English (en)
Inventor
Skerra Arne
Schlehuber Steffen
Original Assignee
Pieris Proteolab Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pieris Proteolab Ag filed Critical Pieris Proteolab Ag
Publication of BRPI0413728A publication Critical patent/BRPI0413728A/pt
Publication of BRPI0413728B1 publication Critical patent/BRPI0413728B1/pt
Publication of BRPI0413728B8 publication Critical patent/BRPI0413728B8/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"muteínas de lipocalina da lágrima". a presente invenção refere-se às novas muteínas derivadas de lipocalina da lágrima ou um homólogo da mesma. especificamente, a invenção refere-se a uma muteína da lágrima humana. a invenção também se refere a uma molécula de ácido nucléico correspondente codificando tal muteína e a um processo para sua geração. a invenção se refere, adicionalmente, a um método para produzir tal muteína. finalmente, a invenção é dirigida a uma composição farmacêutica compreendendo tal muteína de lipocalina, bem como aos vários usos da muteína.
BRPI0413728A 2003-08-25 2004-08-24 muteína da lipocalina da lágrima humana, métodos para geração e para produção de muteína, composição farmacêutica e uso de muteína BRPI0413728B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2003/009404 WO2005019255A1 (en) 2003-08-25 2003-08-25 Muteins of tear lipocalin
PCT/EP2004/009447 WO2005019256A2 (en) 2003-08-25 2004-08-24 Muteins of tear lipocalin

Publications (3)

Publication Number Publication Date
BRPI0413728A BRPI0413728A (pt) 2006-10-24
BRPI0413728B1 BRPI0413728B1 (pt) 2017-05-23
BRPI0413728B8 true BRPI0413728B8 (pt) 2021-05-25

Family

ID=34203142

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413728A BRPI0413728B8 (pt) 2003-08-25 2004-08-24 muteína da lipocalina da lágrima humana, métodos para geração e para produção de muteína, composição farmacêutica e uso de muteína

Country Status (12)

Country Link
US (2) US7585940B2 (pt)
EP (1) EP1660528B1 (pt)
JP (1) JP4856543B2 (pt)
CN (1) CN1871256B (pt)
AT (1) ATE446313T1 (pt)
AU (2) AU2003275958A1 (pt)
BR (1) BRPI0413728B8 (pt)
CA (1) CA2536491C (pt)
DE (1) DE602004023725D1 (pt)
DK (1) DK1660528T3 (pt)
SG (1) SG131109A1 (pt)
WO (2) WO2005019255A1 (pt)

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