BRPI0414331A - método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica - Google Patents

método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica

Info

Publication number
BRPI0414331A
BRPI0414331A BRPI0414331-0A BRPI0414331A BRPI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A
Authority
BR
Brazil
Prior art keywords
bacteria
treatment area
composition
erythrosin
patient treatment
Prior art date
Application number
BRPI0414331-0A
Other languages
English (en)
Inventor
Volker Albrecht
Burkhard Gitter
Original Assignee
Ceramoptecl Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceramoptecl Ind Inc filed Critical Ceramoptecl Ind Inc
Publication of BRPI0414331A publication Critical patent/BRPI0414331A/pt
Publication of BRPI0414331B1 publication Critical patent/BRPI0414331B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

"MéTODO DE DESTRUIçãO DE BACTéRIA NUMA áREA DE TRATAMENTO DO PACIENTE E COMPOSIçãO ANTIMICROBIANA DE TERAPIA FOTODINáMICA". é revelado um método e uma composição para destruição de micróbios, especialmente bactéria, no corpo utilizando Eritrosina B junto com radiação eletromagnética. Num método preferido, uma composição compreendendo Eritrosina B é introduzida numa área de tratamento. Depois de um período suficiente de tempo decorrido, é aplicada radiação de um comprimento de onda apropriado à área para ativar a Eritrosina B e, por uma reação fotodinâmica, destruir a bactéria. A radiação preferida tem um comprimento de onda ao redor de 530 nm. A Eritrosina B é incorporada num gel, que atua de modo a restringir a ação fotodinâmica próxima ao biofilme, assegurando, deste modo, que apenas bactéria não desejada é afetada e a microfiora natural está incólume. Este método é efetivo para destruir pelo menos bactérias Gram-positivas e é particularmente efetivo em áreas em que os meios complexos tais como saliva também estão presentes.
BRPI0414331-0A 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica" BRPI0414331B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US50333903P 2003-09-16 2003-09-16
US60/503,339 2003-09-16
US10/860,297 2004-06-03
US10/860,297 US20050059731A1 (en) 2003-09-16 2004-06-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use
PCT/US2004/028726 WO2005032459A2 (en) 2003-09-16 2004-09-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use

Publications (2)

Publication Number Publication Date
BRPI0414331A true BRPI0414331A (pt) 2006-11-07
BRPI0414331B1 BRPI0414331B1 (pt) 2018-05-29

Family

ID=34278962

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414331-0A BRPI0414331B1 (pt) 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica"

Country Status (7)

Country Link
US (1) US20050059731A1 (pt)
EP (1) EP1778294A4 (pt)
JP (1) JP4943149B2 (pt)
BR (1) BRPI0414331B1 (pt)
MX (1) MXPA06003033A (pt)
RU (1) RU2368375C2 (pt)
WO (1) WO2005032459A2 (pt)

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Also Published As

Publication number Publication date
EP1778294A2 (en) 2007-05-02
MXPA06003033A (es) 2006-12-14
RU2006112562A (ru) 2006-08-10
JP4943149B2 (ja) 2012-05-30
BRPI0414331B1 (pt) 2018-05-29
WO2005032459A3 (en) 2006-10-12
JP2007509034A (ja) 2007-04-12
EP1778294A4 (en) 2010-05-05
US20050059731A1 (en) 2005-03-17
WO2005032459A2 (en) 2005-04-14
RU2368375C2 (ru) 2009-09-27

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
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