BRPI0414331A - método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica - Google Patents

método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica

Info

Publication number
BRPI0414331A
BRPI0414331A BRPI0414331-0A BRPI0414331A BRPI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A
Authority
BR
Brazil
Prior art keywords
bacteria
treatment area
composition
erythrosin
patient treatment
Prior art date
Application number
BRPI0414331-0A
Other languages
English (en)
Inventor
Volker Albrecht
Burkhard Gitter
Original Assignee
Ceramoptecl Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceramoptecl Ind Inc filed Critical Ceramoptecl Ind Inc
Publication of BRPI0414331A publication Critical patent/BRPI0414331A/pt
Publication of BRPI0414331B1 publication Critical patent/BRPI0414331B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

"MéTODO DE DESTRUIçãO DE BACTéRIA NUMA áREA DE TRATAMENTO DO PACIENTE E COMPOSIçãO ANTIMICROBIANA DE TERAPIA FOTODINáMICA". é revelado um método e uma composição para destruição de micróbios, especialmente bactéria, no corpo utilizando Eritrosina B junto com radiação eletromagnética. Num método preferido, uma composição compreendendo Eritrosina B é introduzida numa área de tratamento. Depois de um período suficiente de tempo decorrido, é aplicada radiação de um comprimento de onda apropriado à área para ativar a Eritrosina B e, por uma reação fotodinâmica, destruir a bactéria. A radiação preferida tem um comprimento de onda ao redor de 530 nm. A Eritrosina B é incorporada num gel, que atua de modo a restringir a ação fotodinâmica próxima ao biofilme, assegurando, deste modo, que apenas bactéria não desejada é afetada e a microfiora natural está incólume. Este método é efetivo para destruir pelo menos bactérias Gram-positivas e é particularmente efetivo em áreas em que os meios complexos tais como saliva também estão presentes.
BRPI0414331-0A 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica" BRPI0414331B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US50333903P 2003-09-16 2003-09-16
US60/503,339 2003-09-16
US10/860,297 2004-06-03
US10/860,297 US20050059731A1 (en) 2003-09-16 2004-06-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use
PCT/US2004/028726 WO2005032459A2 (en) 2003-09-16 2004-09-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use

Publications (2)

Publication Number Publication Date
BRPI0414331A true BRPI0414331A (pt) 2006-11-07
BRPI0414331B1 BRPI0414331B1 (pt) 2018-05-29

Family

ID=34278962

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414331-0A BRPI0414331B1 (pt) 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica"

Country Status (7)

Country Link
US (1) US20050059731A1 (pt)
EP (1) EP1778294A4 (pt)
JP (1) JP4943149B2 (pt)
BR (1) BRPI0414331B1 (pt)
MX (1) MXPA06003033A (pt)
RU (1) RU2368375C2 (pt)
WO (1) WO2005032459A2 (pt)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004084973A2 (en) 2003-03-24 2004-10-07 Becton, Dickinson And Company Invisible antimicrobial glove and hand antiseptic
WO2007080453A2 (en) 2005-11-09 2007-07-19 Klox Technologies Inc. Teeth whitening compositions and methods
GB0525504D0 (en) 2005-12-14 2006-01-25 Bristol Myers Squibb Co Antimicrobial composition
US8512294B2 (en) * 2006-07-28 2013-08-20 Becton, Dickinson And Company Vascular access device antimicrobial materials and solutions
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
WO2009052638A1 (en) * 2007-10-25 2009-04-30 Innovotech Inc. Natural photodynamic agents and their use
CN102056629B (zh) 2008-04-04 2013-06-05 新加坡国立大学 一种光敏组成物及其应用
PL2352488T3 (pl) 2008-11-07 2017-07-31 Klox Technologies Inc. Utleniająca, aktywowana światłem kompozycja do odmładzania skóry zawierająca kwas hialuronowy, glukozaminę lub alantoinę
GB0823265D0 (en) * 2008-12-20 2009-01-28 Convatec Technologies Inc Antimicrobial Composition
US8821455B2 (en) * 2009-07-09 2014-09-02 Becton, Dickinson And Company Antimicrobial coating for dermally invasive devices
HUE035716T2 (en) 2009-07-17 2018-05-28 Klox Tech Inc Antibacterial oral composition
US20110065798A1 (en) * 2009-09-17 2011-03-17 Becton, Dickinson And Company Anti-infective lubricant for medical devices and methods for preparing the same
MX2012006175A (es) * 2009-12-21 2012-06-19 Colgate Palmolive Co Metodo para tratar y/o prevenir afecciones causadas por microorganismos, usando un dispositivo oral de luz.
MX2012006170A (es) 2009-12-21 2012-06-19 Colgate Palmolive Co Kit que contiene colorantes de fotosensibilizacion.
DE102011075808B4 (de) * 2010-09-10 2017-06-29 Biolitec Ag Implantat zur Anwendung bei einer photo-dynamischen Behandlung sowie Verfahren zur Herstellung des Implantats
GB201020236D0 (en) 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
WO2013005379A1 (ja) * 2011-07-01 2013-01-10 Ｓｂｉファーマ株式会社 光増感剤又は５－アミノレブリン酸類を用いる光線力学的治療
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
US11116841B2 (en) * 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
KR20210072827A (ko) * 2012-09-14 2021-06-17 광동 클록스 바이오메디컬 그룹 씨오., 엘티디 생체 광자성 용도를 위한 발색단 조합
KR20150082189A (ko) 2012-09-14 2015-07-15 밸리언트 파마슈티컬즈 인터내셔널, 인코퍼레이션 치아미백용 조성물 및 치아미백 방법
WO2014096843A2 (en) 2012-12-20 2014-06-26 Convatec Technologies Inc. Processing of chemically modified cellulosic fibres
US9695323B2 (en) 2013-02-13 2017-07-04 Becton, Dickinson And Company UV curable solventless antimicrobial compositions
US9750928B2 (en) 2013-02-13 2017-09-05 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator
US9327095B2 (en) 2013-03-11 2016-05-03 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US9750927B2 (en) 2013-03-11 2017-09-05 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
GB201308770D0 (en) 2013-05-15 2013-06-26 Convatec Technologies Inc Wound Dressing Comprising an Antimicrobial Composition
HK1219890A1 (zh) 2013-07-03 2017-04-21 广东科洛克生物医药集团有限公司 治疗不癒合伤口的组合物和方法
JP2017509433A (ja) 2014-04-01 2017-04-06 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 組織充填剤組成物および使用方法
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US9675793B2 (en) 2014-04-23 2017-06-13 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
ES2856841T3 (es) 2014-10-31 2021-09-28 Klox Tech Inc Fibras y medios de tela fotoactivables
RU2606834C2 (ru) * 2015-04-17 2017-01-10 Общество с ограниченной ответственностью "РЕВИКСАН" (ООО "РЕВИКСАН") Гель-фотосенсибилизатор для фотодинамической терапии
US10569097B2 (en) 2015-07-28 2020-02-25 Photonmd, Inc. Systems and methods for phototherapeutic modulation of nitric oxide
US12109429B2 (en) 2015-07-28 2024-10-08 Know Bio, Llc Phototherapeutic light for treatment of pathogens
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
FI130369B (en) 2018-10-26 2023-07-28 Koite Health Oy A method for treating biological surfaces
KR20220061106A (ko) 2019-08-02 2022-05-12 코이트 헬스 오와이 전신적으로 적용하는 항생제의 항균 작용을 강화하는 방법
US12447354B2 (en) 2020-03-19 2025-10-21 Know Bio, Llc Illumination devices for inducing biological effects
US11147984B2 (en) 2020-03-19 2021-10-19 Know Bio, Llc Illumination devices for inducing biological effects
US11986666B2 (en) 2020-03-19 2024-05-21 Know Bio, Llc Illumination devices for inducing biological effects
US12011611B2 (en) 2020-03-19 2024-06-18 Know Bio, Llc Illumination devices for inducing biological effects
US11529153B2 (en) 2020-08-21 2022-12-20 University Of Washington Vaccine generation
WO2022040258A1 (en) 2020-08-21 2022-02-24 University Of Washington Disinfection method and apparatus
US11425905B2 (en) 2020-09-02 2022-08-30 University Of Washington Antimicrobial preventive netting
WO2022103775A1 (en) 2020-11-12 2022-05-19 Singletto Inc. Microbial disinfection for personal protection equipment
US12347337B2 (en) 2020-12-10 2025-07-01 Know Bio, Llc Enhanced testing and characterization techniques for phototherapeutic light treatments
US12115384B2 (en) 2021-03-15 2024-10-15 Know Bio, Llc Devices and methods for illuminating tissue to induce biological effects
US11654294B2 (en) 2021-03-15 2023-05-23 Know Bio, Llc Intranasal illumination devices
US12359369B2 (en) 2022-08-11 2025-07-15 Singletto Inc. Skin protection against microbial particles

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4459277A (en) * 1980-10-07 1984-07-10 Kosti Carl M Plaque disclosing dentifrice compositions with solid microcapsules of dye
SE8206250L (sv) * 1982-11-03 1984-05-04 Chemical Dynamics Sweden Ab Reglering av tarmmikroflora
US4647578A (en) * 1983-12-02 1987-03-03 Sterling Drug Inc. Phototoxic insecticidal compositions and method of use thereof
US4634589A (en) * 1984-05-18 1987-01-06 Wurttembergische Parfumerie-Fabrik Gmbh Dentifrice for hypersensitive teeth
ATE159661T1 (de) * 1992-04-30 1997-11-15 Eastman Dental Inst Medikament zur desinfektion der mundhöhle
SK6495A3 (en) * 1992-07-22 1995-07-11 Unilever Nv Method of microorganism killing
US5798112A (en) * 1994-12-09 1998-08-25 The United States Of America As Represented By The Secretary Of Agriculture Phototoxic insecticidal composition and method for controlling insect populations
US5713738A (en) * 1995-12-12 1998-02-03 Britesmile, Inc. Method for whitening teeth
US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
ES2196414T3 (es) * 1997-02-24 2003-12-16 Kuraray Co Composicion antimicrobiana para la deteccion de caries.
SE511276C2 (sv) * 1998-01-09 1999-09-06 Mediteam Dentalutveckling I Go Preparat för användning vid behandling av kariesangrepp
IL123437A0 (en) * 1998-02-24 1998-09-24 Shalev Pinchas Apparatus and method for photothermal destruction of oral bacteria
US6609014B1 (en) * 1999-04-14 2003-08-19 Qlt Inc. Use of PDT to inhibit intimal hyperplasia
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
ES2371948T3 (es) * 1999-08-13 2012-01-11 Provectus Pharmatech, Inc. Medicamentos tópicos mejorados y métodos para el tratamiento fotodinámico de una enfermedad.
JP2001114659A (ja) * 1999-10-13 2001-04-24 Lion Corp 口腔用組成物
US6506791B2 (en) * 2000-08-09 2003-01-14 Jacksonville State University Method of treatment of protozoan infections in fish
CA2437557C (en) * 2001-02-06 2012-07-24 Qlt Inc. Reduced total fluence photodynamic therapy of choroidal neovasculature in amd
CN1551757A (zh) * 2001-09-03 2004-12-01 口腔组合物
US20030044114A1 (en) * 2001-09-06 2003-03-06 Pelka David G. Source wavelength shifting apparatus and method for delivery of one or more selected emission wavelengths
US6561808B2 (en) * 2001-09-27 2003-05-13 Ceramoptec Industries, Inc. Method and tools for oral hygiene

Also Published As

Publication number Publication date
EP1778294A2 (en) 2007-05-02
MXPA06003033A (es) 2006-12-14
WO2005032459A3 (en) 2006-10-12
JP2007509034A (ja) 2007-04-12
RU2368375C2 (ru) 2009-09-27
JP4943149B2 (ja) 2012-05-30
US20050059731A1 (en) 2005-03-17
RU2006112562A (ru) 2006-08-10
EP1778294A4 (en) 2010-05-05
BRPI0414331B1 (pt) 2018-05-29
WO2005032459A2 (en) 2005-04-14

Similar Documents

Publication Publication Date Title
BRPI0414331A (pt) método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica
EP2683442B1 (en) Apparatus for selectively affecting and/or killing bacteria
BRPI0414069A8 (pt) Método de destruição de bactérias em área de tratamento do paciente e respectiva composição terapêutica fotodinâmica antimicrobiana
US7306620B2 (en) Prevention and treatment of skin and nail infections using germicidal light
Caccianiga et al. Clinical, radiographic and microbiological evaluation of high level laser therapy, a new photodynamic therapy protocol, in peri‐implantitis treatment; a pilot experience
BR9715022A (pt) Método para tratar de doenças prostáticas usando formulações de vitamina d por liberação sistemática e/ou prolongada
BR9507506A (pt) Processo para exterminar uma célula processo para tratamento de càncer composição e kit terapéutico
BR9712599A (pt) Processos para o tratamento de um volume particular, de câncer e de um volume de tecido canceroso em tecido e para produzir pelo menos um agente molecular foto-ativo num volume particular de material e aparelhos para o tratamento de um volume particular de tecido de planta ou de animal e para a administração de um tratamento médico foto-dinâmico
ATE339227T1 (de) Beschichtetes medizinsches implantat zur behandlung von gefässerkrankungen
BR0317747A (pt) Método de tratamento terapêutico concomitante de um indivìduo, composição farmacêutica, kit, uso de um primeiro agente e um segundo agente, e, métodos de prevenir ou tratar uma doença relacionada com amilóide-b, doença de alzheimer e insuficiência cognitiva suave
BRPI0606902A2 (pt) composto; método para o tratamento de uma doença ou distúrbio associado a atividade excessiva de bace em um paciente que dele necessite; método para modular a atividade de bace; composição farmacêutica
BR0108175A (pt) Derivados de piperazina e piperidina para o tratamento ou a prevenção de danos neuronais
AU5029599A (en) Methods for eradication of nanobacteria
CY1106259T1 (el) Συνδυασμενη θepαπεια που πepιλαμβανει zd6474 κι ενα ταξανιο
BR0306196A (pt) Método de tratamento de infecções endocavitais ou condições anormais de tecido da superfìcie e aparelho para tratamento de local infectado
CY1115407T1 (el) Θοριο-227 για χρηση στην ακτινοθεραπεια ασθενειων των μαλακων ιστων
DE69607615D1 (de) Neuartige metalloprotease-inhibitoren und diese enthaltende pharmazeutische zusammensetzungen
ES2159043T3 (es) Derivado carboestirilico para el tratamiento de enfermedades oculares.
WO2004024080A3 (en) Treatment of periodontal disease with photosensitizers
ES2183359T3 (es) Agente desinfectante de pezones por inmersion.
BR0313413A (pt) Uso da vacinação beta amilóide juntamente com um inibidor da cox-2 seletivo para o tratamento da doença de alzheimer
DE60018409D1 (de) Verwendung von antiseptika zur herstelllung von arzneimitteln zur prophylaxe und behandlung von infektionen und/ oder funktionellen gewebeumformungen im körperinneren
Nammour et al. Evaluation of dental pulp temperature rise during photo-activated decontamination (PAD) of caries: an in vitro study
BR0312929A (pt) Uso de um composto, e, métodos de tratamento, prevenção ou alìvio de uma doença, distúrbio ou condição de um corpo de animal vivo, e da degeneração macular relacionada com a idade de um corpo de animal vivo
EP2542305A4 (en) ADVANCED ANTIMICROBIAL PDT

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BIOLITEC PHARMA MARKETING LTD. (MY)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/05/2018, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 15A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2530 DE 02-07-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.