BRPI0414331A - método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica - Google Patents

método de destruição de bactéria numa área de tratamento do paciente e composição antimicrobiana de terapia fotodinámica

Info

Publication number
BRPI0414331A
BRPI0414331A BRPI0414331-0A BRPI0414331A BRPI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A BR PI0414331 A BRPI0414331 A BR PI0414331A
Authority
BR
Brazil
Prior art keywords
bacteria
treatment area
composition
erythrosin
patient treatment
Prior art date
Application number
BRPI0414331-0A
Other languages
English (en)
Inventor
Volker Albrecht
Burkhard Gitter
Original Assignee
Ceramoptecl Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceramoptecl Ind Inc filed Critical Ceramoptecl Ind Inc
Publication of BRPI0414331A publication Critical patent/BRPI0414331A/pt
Publication of BRPI0414331B1 publication Critical patent/BRPI0414331B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

"MéTODO DE DESTRUIçãO DE BACTéRIA NUMA áREA DE TRATAMENTO DO PACIENTE E COMPOSIçãO ANTIMICROBIANA DE TERAPIA FOTODINáMICA". é revelado um método e uma composição para destruição de micróbios, especialmente bactéria, no corpo utilizando Eritrosina B junto com radiação eletromagnética. Num método preferido, uma composição compreendendo Eritrosina B é introduzida numa área de tratamento. Depois de um período suficiente de tempo decorrido, é aplicada radiação de um comprimento de onda apropriado à área para ativar a Eritrosina B e, por uma reação fotodinâmica, destruir a bactéria. A radiação preferida tem um comprimento de onda ao redor de 530 nm. A Eritrosina B é incorporada num gel, que atua de modo a restringir a ação fotodinâmica próxima ao biofilme, assegurando, deste modo, que apenas bactéria não desejada é afetada e a microfiora natural está incólume. Este método é efetivo para destruir pelo menos bactérias Gram-positivas e é particularmente efetivo em áreas em que os meios complexos tais como saliva também estão presentes.
BRPI0414331-0A 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica" BRPI0414331B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US50333903P 2003-09-16 2003-09-16
US60/503,339 2003-09-16
US10/860,297 US20050059731A1 (en) 2003-09-16 2004-06-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use
US10/860,297 2004-06-03
PCT/US2004/028726 WO2005032459A2 (en) 2003-09-16 2004-09-03 Erythrosin-based antimicrobial photodynamic therapy compound and its use

Publications (2)

Publication Number Publication Date
BRPI0414331A true BRPI0414331A (pt) 2006-11-07
BRPI0414331B1 BRPI0414331B1 (pt) 2018-05-29

Family

ID=34278962

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414331-0A BRPI0414331B1 (pt) 2003-09-16 2004-09-03 "composição antimicrobiana de terapia fotodinâmica"

Country Status (7)

Country Link
US (1) US20050059731A1 (pt)
EP (1) EP1778294A4 (pt)
JP (1) JP4943149B2 (pt)
BR (1) BRPI0414331B1 (pt)
MX (1) MXPA06003033A (pt)
RU (1) RU2368375C2 (pt)
WO (1) WO2005032459A2 (pt)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7488757B2 (en) 2003-03-24 2009-02-10 Becton, Dickinson And Company Invisible antimicrobial glove and hand antiseptic
PT1951184E (pt) 2005-11-09 2012-04-10 Klox Technologies Inc Composições e métodos para branqueamento de dentes
GB0525504D0 (en) 2005-12-14 2006-01-25 Bristol Myers Squibb Co Antimicrobial composition
US8512294B2 (en) * 2006-07-28 2013-08-20 Becton, Dickinson And Company Vascular access device antimicrobial materials and solutions
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
US20100266716A1 (en) * 2007-10-25 2010-10-21 Olson Merle E Natural Photodynamic Agents and their use
SG191641A1 (en) * 2008-04-04 2013-07-31 Univ Singapore A photosensitising composition and its uses
KR101835047B1 (ko) 2008-11-07 2018-03-08 클록스 테크놀로지스 인크. 히알루론산, 글루코사민 또는 알란토인을 포함하는 산화성의 광활성화된 피부 회춘용 조성물
GB0823265D0 (en) * 2008-12-20 2009-01-28 Convatec Technologies Inc Antimicrobial Composition
US8821455B2 (en) * 2009-07-09 2014-09-02 Becton, Dickinson And Company Antimicrobial coating for dermally invasive devices
CA2767889C (en) 2009-07-17 2017-01-03 Klox Technologies Inc. Antibacterial oral composition
US20110065798A1 (en) * 2009-09-17 2011-03-17 Becton, Dickinson And Company Anti-infective lubricant for medical devices and methods for preparing the same
CA2784358A1 (en) 2009-12-21 2011-07-14 Colgate-Palmolive Company Kit containing photosensitizing dyes
CA2783609A1 (en) * 2009-12-21 2011-06-30 Colgate-Palmolive Company Method of treating and/or preventing conditions caused by microorganisms using an oral light device
DE102011075808B4 (de) * 2010-09-10 2017-06-29 Biolitec Ag Implantat zur Anwendung bei einer photo-dynamischen Behandlung sowie Verfahren zur Herstellung des Implantats
GB201020236D0 (en) 2010-11-30 2011-01-12 Convatec Technologies Inc A composition for detecting biofilms on viable tissues
JP5885743B2 (ja) * 2011-07-01 2016-03-15 Ｓｂｉファーマ株式会社 光増感剤又は５−アミノレブリン酸類を用いる光線力学的治療
US11116841B2 (en) * 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) * 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
EP3329938B1 (en) * 2012-09-14 2021-06-23 KLOX Technologies, Inc. Chromophore combinations for biophotonic uses
BR112015005593B1 (pt) 2012-09-14 2019-09-24 Valeant Pharmaceuticals International, Inc. Método para branqueamento de dentes
JP2016507663A (ja) 2012-12-20 2016-03-10 コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ 化学修飾セルロース系繊維の加工
US9750928B2 (en) 2013-02-13 2017-09-05 Becton, Dickinson And Company Blood control IV catheter with stationary septum activator
US9695323B2 (en) 2013-02-13 2017-07-04 Becton, Dickinson And Company UV curable solventless antimicrobial compositions
US9750927B2 (en) 2013-03-11 2017-09-05 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US9327095B2 (en) 2013-03-11 2016-05-03 Becton, Dickinson And Company Blood control catheter with antimicrobial needle lube
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
GB201308770D0 (en) 2013-05-15 2013-06-26 Convatec Technologies Inc Wound Dressing Comprising an Antimicrobial Composition
EP3016686A4 (en) * 2013-07-03 2017-01-25 Klox Technologies Inc. Biophotonic compositions comprising a chromophore and a gelling agent for treating wounds
CN106413766A (zh) 2014-04-01 2017-02-15 克洛克斯科技公司 组织填料组合物及使用方法
US10376686B2 (en) 2014-04-23 2019-08-13 Becton, Dickinson And Company Antimicrobial caps for medical connectors
US9789279B2 (en) 2014-04-23 2017-10-17 Becton, Dickinson And Company Antimicrobial obturator for use with vascular access devices
US9675793B2 (en) 2014-04-23 2017-06-13 Becton, Dickinson And Company Catheter tubing with extraluminal antimicrobial coating
US10232088B2 (en) 2014-07-08 2019-03-19 Becton, Dickinson And Company Antimicrobial coating forming kink resistant feature on a vascular access device
CA2966010C (en) 2014-10-31 2023-04-11 Klox Technologies Inc. Photoactivatable fibers and fabric media
RU2606834C2 (ru) * 2015-04-17 2017-01-10 Общество с ограниченной ответственностью "РЕВИКСАН" (ООО "РЕВИКСАН") Гель-фотосенсибилизатор для фотодинамической терапии
WO2017019836A1 (en) 2015-07-28 2017-02-02 Photonmd, Llc Systems and methods for phototherapeutic modulation of nitric oxide
US12109429B2 (en) 2015-07-28 2024-10-08 Know Bio, Llc Phototherapeutic light for treatment of pathogens
US10493244B2 (en) 2015-10-28 2019-12-03 Becton, Dickinson And Company Extension tubing strain relief
FI130369B (en) * 2018-10-26 2023-07-28 Koite Health Oy A method for treating biological surfaces
JP2022543103A (ja) * 2019-08-02 2022-10-07 コイテ ヘルス オイ 全身投与抗生物質の抗微生物作用を増強する方法
US12011611B2 (en) 2020-03-19 2024-06-18 Know Bio, Llc Illumination devices for inducing biological effects
US11147984B2 (en) 2020-03-19 2021-10-19 Know Bio, Llc Illumination devices for inducing biological effects
US12447354B2 (en) 2020-03-19 2025-10-21 Know Bio, Llc Illumination devices for inducing biological effects
US11986666B2 (en) 2020-03-19 2024-05-21 Know Bio, Llc Illumination devices for inducing biological effects
US11529153B2 (en) 2020-08-21 2022-12-20 University Of Washington Vaccine generation
US11612669B2 (en) 2020-08-21 2023-03-28 University Of Washington Disinfection method and apparatus
US11425905B2 (en) 2020-09-02 2022-08-30 University Of Washington Antimicrobial preventive netting
WO2022103775A1 (en) 2020-11-12 2022-05-19 Singletto Inc. Microbial disinfection for personal protection equipment
US12347337B2 (en) 2020-12-10 2025-07-01 Know Bio, Llc Enhanced testing and characterization techniques for phototherapeutic light treatments
US11654294B2 (en) 2021-03-15 2023-05-23 Know Bio, Llc Intranasal illumination devices
US12115384B2 (en) 2021-03-15 2024-10-15 Know Bio, Llc Devices and methods for illuminating tissue to induce biological effects
US12359369B2 (en) 2022-08-11 2025-07-15 Singletto Inc. Skin protection against microbial particles

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4459277A (en) * 1980-10-07 1984-07-10 Kosti Carl M Plaque disclosing dentifrice compositions with solid microcapsules of dye
SE8206250L (sv) * 1982-11-03 1984-05-04 Chemical Dynamics Sweden Ab Reglering av tarmmikroflora
US4647578A (en) * 1983-12-02 1987-03-03 Sterling Drug Inc. Phototoxic insecticidal compositions and method of use thereof
US4634589A (en) * 1984-05-18 1987-01-06 Wurttembergische Parfumerie-Fabrik Gmbh Dentifrice for hypersensitive teeth
CA2134479C (en) * 1992-04-30 2007-09-04 Michael Wilson Laser treatment
ES2130276T3 (es) * 1992-07-22 1999-07-01 Unilever Nv Mejoras en o relacionadas con composiciones germicidas.
US5798112A (en) * 1994-12-09 1998-08-25 The United States Of America As Represented By The Secretary Of Agriculture Phototoxic insecticidal composition and method for controlling insect populations
US5713738A (en) * 1995-12-12 1998-02-03 Britesmile, Inc. Method for whitening teeth
US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
US6084005A (en) * 1997-02-24 2000-07-04 Kuraray Co., Ltd. Antimicrobial caries-detecting composition
SE511276C2 (sv) * 1998-01-09 1999-09-06 Mediteam Dentalutveckling I Go Preparat för användning vid behandling av kariesangrepp
IL123437A0 (en) * 1998-02-24 1998-09-24 Shalev Pinchas Apparatus and method for photothermal destruction of oral bacteria
US6609014B1 (en) * 1999-04-14 2003-08-19 Qlt Inc. Use of PDT to inhibit intimal hyperplasia
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
ES2371948T3 (es) * 1999-08-13 2012-01-11 Provectus Pharmatech, Inc. Medicamentos tópicos mejorados y métodos para el tratamiento fotodinámico de una enfermedad.
JP2001114659A (ja) * 1999-10-13 2001-04-24 Lion Corp 口腔用組成物
US6506791B2 (en) * 2000-08-09 2003-01-14 Jacksonville State University Method of treatment of protozoan infections in fish
EP1357946B1 (en) * 2001-02-06 2008-03-26 QLT Inc. Photodynamic therapy with reduced fluence rate
WO2003020230A1 (en) * 2001-09-03 2003-03-13 Unilever N.V. Oral composition
US20030044114A1 (en) * 2001-09-06 2003-03-06 Pelka David G. Source wavelength shifting apparatus and method for delivery of one or more selected emission wavelengths
US6561808B2 (en) * 2001-09-27 2003-05-13 Ceramoptec Industries, Inc. Method and tools for oral hygiene

Also Published As

Publication number Publication date
WO2005032459A3 (en) 2006-10-12
WO2005032459A2 (en) 2005-04-14
US20050059731A1 (en) 2005-03-17
JP2007509034A (ja) 2007-04-12
RU2368375C2 (ru) 2009-09-27
JP4943149B2 (ja) 2012-05-30
MXPA06003033A (es) 2006-12-14
BRPI0414331B1 (pt) 2018-05-29
EP1778294A4 (en) 2010-05-05
EP1778294A2 (en) 2007-05-02
RU2006112562A (ru) 2006-08-10

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