BRPI0414694A - pró-fármaco(s) aciloximetilcarbamato de oxazolidinonas - Google Patents

pró-fármaco(s) aciloximetilcarbamato de oxazolidinonas

Info

Publication number: BRPI0414694A
Authority: BR; Brazil
Prior art keywords: acyloxymethylcarbamate; oxazolidinone; prodrug; present; gram
Prior art date: 2003-09-23

Application number

BRPI0414694-8A

Other languages

English (en)

Portuguese (pt)

Inventor

Vara Prasad Venkata Na Josyula

Robert C Gadwood

Lisa Marie Thomasco

Ji-Young Kim

Allison Laura Choy

Frederick Earl Boyer

Original Assignee

Pharmacia & Upjohn Co Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-23

Filing date

2004-09-13

Publication date

2006-11-28

2004-09-13 Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc

2006-11-28 Publication of BRPI0414694A publication Critical patent/BRPI0414694A/pt

Links

IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
229940002612 prodrug Drugs 0.000 title 1
239000000651 prodrug Substances 0.000 title 1
241000894006 Bacteria Species 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0414694-8A 2003-09-23 2004-09-13 pró-fármaco(s) aciloximetilcarbamato de oxazolidinonas BRPI0414694A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US50532903P	2003-09-23	2003-09-23
PCT/IB2004/002983 WO2005028473A1 (fr)	2003-09-23	2004-09-13	Bioprecurseurs acyloxymethylcarbamate des oxazolidinones

Publications (1)

Publication Number	Publication Date
BRPI0414694A true BRPI0414694A (pt)	2006-11-28

Family

ID=34375571

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0414694-8A BRPI0414694A (pt)	2003-09-23	2004-09-13	pró-fármaco(s) aciloximetilcarbamato de oxazolidinonas

Country Status (10)

Country	Link
US (1)	US7265140B2 (fr)
EP (1)	EP1668005B1 (fr)
JP (1)	JP2007505890A (fr)
AT (1)	ATE353894T1 (fr)
BR (1)	BRPI0414694A (fr)
CA (1)	CA2539848A1 (fr)
DE (1)	DE602004004808T2 (fr)
ES (1)	ES2278342T3 (fr)
MX (1)	MXPA06003124A (fr)
WO (1)	WO2005028473A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004076798A2 (fr)	2003-02-26	2004-09-10	Enventure Global Technology	Appareil d'expansion radiale et de deformation plastique d'un element tubulaire
KR20110097942A (ko) *	2003-08-20	2011-08-31	제노포트 인코포레이티드	아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
ES2405329T3 (es) *	2003-12-30	2013-05-30	Xenoport, Inc.	Síntesis de profármacos de carbarnato de aciloxialquilo y productos intermedios de los mismos
WO2005113520A1 (fr) *	2004-05-20	2005-12-01	Pharmacia & Upjohn Company Llc	2,3,5-trifluorphenyl oxazolidinones substitues a utiliser en tant qu'agents antibacteriens
DE102006007146A1 (de)	2006-02-16	2007-08-23	Bayer Healthcare Ag	Aminoacyl-Prodrugs
CA2645031A1 (fr)	2006-03-07	2007-09-13	Bristol-Myers Squibb Company	Composes de promedicament de pyrrolotriazine aniline utiles en tant qu'inhibiteurs de la kinase
US7776855B2 (en) *	2006-07-27	2010-08-17	Janssen Pharmaceutica N.V.	Antimicrobial oxazolidinone prodrugs
DE102006039589A1 (de)	2006-08-24	2008-03-06	Bayer Healthcare Ag	Aminoacyl-Prodrugs II
DE102007028407A1 (de) *	2007-06-20	2008-12-24	Bayer Healthcare Ag	Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) *	2007-06-20	2008-12-24	Bayer Healthcare Ag	Substituierte Oxazolidinone und ihre Verwendung
DE102007032345A1 (de) *	2007-07-11	2009-01-15	Bayer Healthcare Ag	Aminoacyl-Prodrugs
DE102007032344A1 (de)	2007-07-11	2009-01-15	Bayer Healthcare Ag	Prodrug-Derivate von 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3-carboxamid
DE102007032347A1 (de)	2007-07-11	2009-01-15	Bayer Healthcare Ag	Aminoacyl-Prodrugs
US20100069441A1 (en)	2008-09-02	2010-03-18	Mikhail Fedorovich Gordeev	Antimicrobial indoline compounds for treatment of bacterial infections
CN101798302B (zh)	2009-02-06	2014-11-05	上海盟科药业有限公司	抗生素类药物1-(邻-氟苯基)二氢吡啶酮的合成及生产的方法和工艺
DE102010028362A1 (de)	2010-04-29	2011-11-03	Bayer Schering Pharma Aktiengesellschaft	Herstellverfahren
US20120065170A1 (en)	2010-09-10	2012-03-15	Micurx Pharmaceuticals, Inc.	Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections
WO2013088255A1 (fr) *	2011-12-15	2013-06-20	Alkermes Pharma Ireland Limited	Promédicaments de composés amine secondaires
US9145411B2 (en)	2012-08-02	2015-09-29	Asana Biosciences, Llc	Substituted amino-pyrimidine derivatives
CN105612166B (zh)	2014-02-21	2019-02-19	上海盟科药业有限公司	治疗用水溶性(o-羰基)氨基磷酸酯前药
GB201518950D0 (en) *	2015-10-27	2015-12-09	Glaxosmithkline Ip Dev Ltd	Compound
WO2019037791A1 (fr) *	2017-08-25	2019-02-28	广州市恒诺康医药科技有限公司	Promédicament de rasagiline à action prolongée, son procédé de préparation et son utilisation
WO2021184339A1 (fr)	2020-03-20	2021-09-23	Merck Sharp & Dohme Corp.	Composé d'oxazolidinone et procédés d'utilisation de celui-ci comme agent antibactérien
JP2024516114A (ja) *	2021-04-07	2024-04-12	コスマスセラピューティックスディベロップメントインコーポレイテッド	メラトニン受容体の新規調節因子、ならびにその製造方法および使用
EP4441066A1 (fr) *	2021-11-29	2024-10-09	Hongene Biotech Corporation	Synthèse de nucléosides protégés 2' acétyl-ester
CN119431373B (zh) *	2024-07-24	2025-08-08	科睿迪(南京)医药科技有限公司	一种β-内酰胺酶抑制剂及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2228647A1 (fr)	1995-09-01	1997-03-13	Pharmacia & Upjohn Company	Pheniloxazolidinones presentant une liaison c-c avec des structures heterocycliques a 4-8 elements
EP1133493A1 (fr) *	1998-11-27	2001-09-19	PHARMACIA & UPJOHN COMPANY	Agents antibacteriens oxazolidinone a fonction thiocarbonyle
EA005567B1 (ru) *	1999-12-21	2005-04-28	Фармация Энд Апджон Компани	Оксазолидиноны, обладающие сульфоксиминовой функциональностью
GB0108793D0 (en) *	2001-04-07	2001-05-30	Astrazeneca Ab	Chemical compounds
GB0108764D0 (en) *	2001-04-07	2001-05-30	Astrazeneca Ab	Chemical compounds
JP4208243B2 (ja) *	2002-01-24	2009-01-14	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	抗微生物性ジヒドロチアジンおよびジヒドロチオピランオキサゾリジノン
TW200403240A (en) *	2002-06-28	2004-03-01	Upjohn Co	Difluorothioacetamides of oxazolidinones as antibacterial agents

2004
- 2004-09-09 US US10/937,187 patent/US7265140B2/en not_active Expired - Fee Related
- 2004-09-13 AT AT04769372T patent/ATE353894T1/de not_active IP Right Cessation
- 2004-09-13 CA CA002539848A patent/CA2539848A1/fr not_active Abandoned
- 2004-09-13 ES ES04769372T patent/ES2278342T3/es not_active Expired - Lifetime
- 2004-09-13 MX MXPA06003124A patent/MXPA06003124A/es not_active Application Discontinuation
- 2004-09-13 JP JP2006526723A patent/JP2007505890A/ja not_active Withdrawn
- 2004-09-13 BR BRPI0414694-8A patent/BRPI0414694A/pt not_active IP Right Cessation
- 2004-09-13 EP EP04769372A patent/EP1668005B1/fr not_active Expired - Lifetime
- 2004-09-13 DE DE602004004808T patent/DE602004004808T2/de not_active Expired - Fee Related
- 2004-09-13 WO PCT/IB2004/002983 patent/WO2005028473A1/fr not_active Ceased

Also Published As

Publication number	Publication date
EP1668005A1 (fr)	2006-06-14
ATE353894T1 (de)	2007-03-15
DE602004004808T2 (de)	2007-12-06
US20050267104A1 (en)	2005-12-01
EP1668005B1 (fr)	2007-02-14
MXPA06003124A (es)	2006-06-20
CA2539848A1 (fr)	2005-03-31
ES2278342T3 (es)	2007-08-01
JP2007505890A (ja)	2007-03-15
US7265140B2 (en)	2007-09-04
WO2005028473A1 (fr)	2005-03-31
DE602004004808D1 (de)	2007-03-29

Legal Events

Date	Code	Title	Description
2012-05-15	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2012-10-09	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.

Publication	Publication Date	Title
DE602004004808D1 (de)	2007-03-29	Acyloxymethylcarbamat-prodrugs von oxazolidinonen
MX351589B (es)	2017-10-20	Antibioticos de oxazolidinona.
HUP0400446A2 (hu)	2004-09-28	Azitromicin kristályformái
DE60327438D1 (de)	2009-06-10	Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen
CO5570678A2 (es)	2005-10-31	N-alquilo-4-metileneamino-3-hidroxilo-2-piridonas como anti- microbianos
IL187904A (en)	2015-05-31	Use of quinoline derivatives for the preparation of bacterial preparations for the treatment of bacteria caused by bacteria
GEP20094834B (en)	2009-11-25	Macrolides, pharmaceutical compositions containing them and their use for treatment of bacterial infections
MXPA05009352A (es)	2006-03-13	Metodos y composiciones para tratamiento y prevencion de staphylococcus y otras infecciones bacterianas.
ES2186550B2 (es)	2003-11-16	Nuevos derivados de oxazolidinonas como antibacterianos.
DE602004012269D1 (de)	2008-04-17	Quervernetzte glycopeptid-cephalosporin-antibiotika
DE602004024393D1 (de)	2010-01-14	Quervernetzte glycopeptid-cephalosporin-antibiotika
NO20055893L (no)	2006-03-14	Nye linkomycinderivativer med antimikrobiell aktivitet
MXPA05008960A (es)	2005-11-04	Oxazolidinonas de indolona antibacteriales, intermedios para su preparacion y composiciones farmaceuticas que las contienen.
UY28542A1 (es)	2005-04-29	Amidas macrocíclicas antibacterianas
TW200740800A (en)	2007-11-01	Oxazolidinone compounds, and compositions and methods related thereto
WO2006120563A3 (fr)	2007-04-12	Agents antibacteriens
DK1656143T3 (da)	2012-02-06	Quinolon-antibiotika til behandling af periodontale infektioner
DK1558580T3 (da)	2008-01-14	N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner
ATE449775T1 (de)	2009-12-15	Carbacephem beta-lactam-antibiotika
NO20043445L (no)	2004-08-18	Kombinasjonsterapi for behandling av bakterielle infeksjoner
EA200800151A1 (ru)	2008-06-30	Производные хинолина в качестве антибактериальных агентов
DE502005010850D1 (de)	2011-02-24	Antibakterielle amid-makrozyklen iv
MY142727A (en)	2010-12-31	Preventing vertical endoparasite infections
DK1516626T3 (da)	2007-04-30	Teicoplanin-sammensætning med forbedret antibiotisk aktivitet
CL2004001343A1 (es)	2005-04-22	Compuesto derivado del ester de 3,3-dimetil-4,4,7-trioxo-4-tia-1-aza-biciclo [3.2.0]-heptano-2-carboxilico, composicion farmaceutica, inhibidores de beta lactama, utiles para tratar una infeccion bacteriana.