BRPI0414968A - preparação de infusão contendo ácido (2r)-2-propiloctanóico como o ingrediente ativo - Google Patents
preparação de infusão contendo ácido (2r)-2-propiloctanóico como o ingrediente ativoInfo
- Publication number
- BRPI0414968A BRPI0414968A BRPI0414968-8A BRPI0414968A BRPI0414968A BR PI0414968 A BRPI0414968 A BR PI0414968A BR PI0414968 A BRPI0414968 A BR PI0414968A BR PI0414968 A BRPI0414968 A BR PI0414968A
- Authority
- BR
- Brazil
- Prior art keywords
- infusion
- acid
- active ingredient
- salt
- infusion preparation
- Prior art date
Links
- 238000001802 infusion Methods 0.000 title abstract 5
- 238000002360 preparation method Methods 0.000 title abstract 4
- YCYMCMYLORLIJX-SNVBAGLBSA-N (2r)-2-propyloctanoic acid Chemical compound CCCCCC[C@H](C(O)=O)CCC YCYMCMYLORLIJX-SNVBAGLBSA-N 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 238000001990 intravenous administration Methods 0.000 abstract 2
- 239000010953 base metal Substances 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 229910000000 metal hydroxide Inorganic materials 0.000 abstract 1
- 150000004692 metal hydroxides Chemical class 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
"PREPARAçãO DE INFUSãO CONTENDO áCIDO (2R)-2-PROPILOCTANóICO COMO O INGREDIENTE ATIVO". Uma preparação de infusão que contém ácido (2R)-2propiloctanóico ou um sal do mesmo, útil no tratamento de doenças neurodegenerativas, e um íon de metal básico fornecido a partir de um sal de metal de um ácido fraco ou um hidróxido de metal preferivelmente em uma quantidade de cerca de 1 a 5 equivalentes por por equivalente do ácido (2R)-2-própiloctanóico ou um sal do mesmo, opcionalmente em conjunto com outro (s) componente(s) de infusão. Essa preparação de infusão apresenta um valor de pH adequado para administração intravenosa, e é útil em administração intravenosa contínua sem a necessidade de qualquer pré-tratamento tal como dissolução ou diluição antes do uso.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003345125 | 2003-10-03 | ||
| PCT/JP2004/014896 WO2005032538A1 (ja) | 2003-10-03 | 2004-10-01 | (２ｒ)−２−プロピルオクタン酸を有効成分とする輸液製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0414968A true BRPI0414968A (pt) | 2006-11-07 |
Family
ID=34419442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0414968-8A BRPI0414968A (pt) | 2003-10-03 | 2004-10-01 | preparação de infusão contendo ácido (2r)-2-propiloctanóico como o ingrediente ativo |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20070066686A1 (pt) |
| EP (1) | EP1669066A4 (pt) |
| JP (1) | JP4715516B2 (pt) |
| CN (1) | CN1889941A (pt) |
| AU (1) | AU2004277828A1 (pt) |
| BR (1) | BRPI0414968A (pt) |
| CA (1) | CA2540671A1 (pt) |
| EC (1) | ECSP066476A (pt) |
| IL (1) | IL174691A0 (pt) |
| IS (1) | IS8428A (pt) |
| MA (1) | MA28143A1 (pt) |
| MX (1) | MXPA06003605A (pt) |
| NO (1) | NO20061458L (pt) |
| RU (1) | RU2006114834A (pt) |
| SG (1) | SG146690A1 (pt) |
| WO (1) | WO2005032538A1 (pt) |
| ZA (1) | ZA200602689B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7980168B2 (en) * | 2007-06-26 | 2011-07-19 | Maurer Scott D | Hot beverage maker with filter deforming member |
| US20100130619A1 (en) * | 2008-11-24 | 2010-05-27 | Joseph Schwarz | Pharmaceutical composition for parenteral administration of idebenone |
| CN104931424A (zh) * | 2015-05-06 | 2015-09-23 | 山东师范大学 | 一种改进的z扫描非线性测量的实验装置及方法 |
| CN109593676B (zh) * | 2018-12-21 | 2023-04-07 | 江苏大学 | 一种用于酸菜发酵液中微生物分离的培养基及其制备方法 |
| EP3923719A4 (en) * | 2019-02-14 | 2022-11-30 | North Grove Investments, Inc. | Compositions for maintaining the viability of living and static biological material, methods of making and the uses thereof |
| RU2699222C1 (ru) * | 2019-04-29 | 2019-09-04 | Алексей Владимирович Воронов | Солевой электролитный раствор для проведения энтеральных инфузий |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69408373T2 (de) * | 1993-06-01 | 1998-07-16 | Ono Pharmaceutical Co | Pentansäurederivate |
| JPH0782146A (ja) * | 1993-07-23 | 1995-03-28 | Sagami Chem Res Center | 抗痴呆薬 |
| JPH07285911A (ja) * | 1994-04-20 | 1995-10-31 | New Japan Chem Co Ltd | 脂肪族モノカルボン酸組成物 |
| JPH0853351A (ja) * | 1994-08-11 | 1996-02-27 | Sagami Chem Res Center | 酵素阻害剤、血管新生抑制剤、および癌転移抑制剤 |
| US6043223A (en) * | 1997-11-12 | 2000-03-28 | The Regents Of The University Of California | Enhanced opening of abnormal brain tissue capillaries |
| TWI268921B (en) * | 1999-02-18 | 2006-12-21 | Ono Pharmaceutical Co | A process for preparing (2R)-2-propyloctanoic acid |
| WO2001092289A1 (en) * | 2000-05-31 | 2001-12-06 | Japan Science And Technology Corporation | SKIN TISSUE REGENERATION PROMOTERS COMPRISING GINSENOSIDE Rb1 |
| KR100759771B1 (ko) * | 2000-07-18 | 2007-10-04 | 오노 야꾸힝 고교 가부시키가이샤 | 성상세포 기능 개선제를 유효 성분으로 함유하는 파킨슨병치료제 |
| JP4706950B2 (ja) * | 2000-07-18 | 2011-06-22 | 小野薬品工業株式会社 | アストロサイト機能改善剤を有効成分として含有するパーキンソン病治療剤 |
| CA2453478A1 (en) * | 2001-07-18 | 2003-01-30 | Ono Pharmaceutical Co., Ltd. | Agent for treatment of cerebral ischemic diseases |
-
2004
- 2004-10-01 AU AU2004277828A patent/AU2004277828A1/en not_active Abandoned
- 2004-10-01 RU RU2006114834/15A patent/RU2006114834A/ru not_active Application Discontinuation
- 2004-10-01 WO PCT/JP2004/014896 patent/WO2005032538A1/ja not_active Ceased
- 2004-10-01 JP JP2005514508A patent/JP4715516B2/ja not_active Expired - Fee Related
- 2004-10-01 EP EP04792178A patent/EP1669066A4/en not_active Withdrawn
- 2004-10-01 CA CA002540671A patent/CA2540671A1/en not_active Abandoned
- 2004-10-01 BR BRPI0414968-8A patent/BRPI0414968A/pt not_active IP Right Cessation
- 2004-10-01 US US10/574,476 patent/US20070066686A1/en not_active Abandoned
- 2004-10-01 SG SG200807295-1A patent/SG146690A1/en unknown
- 2004-10-01 CN CNA2004800356843A patent/CN1889941A/zh active Pending
- 2004-10-01 MX MXPA06003605A patent/MXPA06003605A/es not_active Application Discontinuation
-
2006
- 2006-03-30 IL IL174691A patent/IL174691A0/en unknown
- 2006-03-31 NO NO20061458A patent/NO20061458L/no not_active Application Discontinuation
- 2006-03-31 ZA ZA200602689A patent/ZA200602689B/en unknown
- 2006-04-03 EC EC2006006476A patent/ECSP066476A/es unknown
- 2006-04-25 IS IS8428A patent/IS8428A/is unknown
- 2006-05-02 MA MA28992A patent/MA28143A1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200602689B (en) | 2007-06-27 |
| EP1669066A1 (en) | 2006-06-14 |
| NO20061458L (no) | 2006-07-03 |
| WO2005032538A1 (ja) | 2005-04-14 |
| SG146690A1 (en) | 2008-10-30 |
| AU2004277828A1 (en) | 2005-04-14 |
| CA2540671A1 (en) | 2005-04-14 |
| CN1889941A (zh) | 2007-01-03 |
| ECSP066476A (es) | 2007-03-29 |
| RU2006114834A (ru) | 2007-11-20 |
| IS8428A (is) | 2006-04-25 |
| MA28143A1 (fr) | 2006-09-01 |
| JP4715516B2 (ja) | 2011-07-06 |
| JPWO2005032538A1 (ja) | 2006-12-14 |
| MXPA06003605A (es) | 2006-06-14 |
| US20070066686A1 (en) | 2007-03-22 |
| IL174691A0 (en) | 2006-08-20 |
| EP1669066A4 (en) | 2009-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |