BRPI0415215A - aplicação de um polifenol para o tratamento de uma lesão cancerosa ou pré-cancerosa da pele - Google Patents
aplicação de um polifenol para o tratamento de uma lesão cancerosa ou pré-cancerosa da peleInfo
- Publication number
- BRPI0415215A BRPI0415215A BRPI0415215-8A BRPI0415215A BRPI0415215A BR PI0415215 A BRPI0415215 A BR PI0415215A BR PI0415215 A BRPI0415215 A BR PI0415215A BR PI0415215 A BRPI0415215 A BR PI0415215A
- Authority
- BR
- Brazil
- Prior art keywords
- polyphenol
- treatment
- application
- cancerous
- precancerous skin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51010103P | 2003-10-09 | 2003-10-09 | |
| US60/510,101 | 2003-10-09 | ||
| PCT/EP2004/011300 WO2005037300A1 (en) | 2003-10-09 | 2004-10-08 | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0415215A true BRPI0415215A (pt) | 2006-12-05 |
| BRPI0415215B1 BRPI0415215B1 (pt) | 2021-02-23 |
| BRPI0415215B8 BRPI0415215B8 (pt) | 2021-05-25 |
Family
ID=34465119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0415215A BRPI0415215B8 (pt) | 2003-10-09 | 2004-10-08 | uso de polifenol na preparação de medicamento |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7910138B2 (pt) |
| EP (2) | EP1684780B1 (pt) |
| AR (1) | AR045865A1 (pt) |
| AU (1) | AU2004281525B2 (pt) |
| BR (1) | BRPI0415215B8 (pt) |
| CA (1) | CA2541405C (pt) |
| ES (1) | ES2391561T3 (pt) |
| IL (1) | IL174434A0 (pt) |
| MX (1) | MXPA06003404A (pt) |
| NZ (1) | NZ546323A (pt) |
| RU (1) | RU2366447C2 (pt) |
| WO (1) | WO2005037300A1 (pt) |
| ZA (1) | ZA200602544B (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE417611T1 (de) * | 2001-11-19 | 2009-01-15 | Medigene Ag | Arzneimittel zur behandlung von viralen haut- und tumorerkrankungen |
| US20050079235A1 (en) * | 2003-10-09 | 2005-04-14 | Eggert Stockfleth | Use of a polyphenol for the treatment of actinic keratosis |
| AU2006222556B2 (en) * | 2005-03-11 | 2011-09-29 | Armaron Bio Pty Ltd | Flavonoid compounds and uses thereof |
| RU2375089C1 (ru) * | 2008-07-14 | 2009-12-10 | Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) | Способ кожесохраняющего, радикального лечения плоскоклеточного рака кожи без метастазов в региональные лимфатические узлы |
| RU2413484C1 (ru) * | 2009-11-10 | 2011-03-10 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ хирургического лечения доброкачественных новообразований век |
| RU2437672C1 (ru) * | 2010-06-11 | 2011-12-27 | Сергей Владимирович Енгашев | Способ очистки экстракта зеленого чая, лекарственное средство на его основе и способ профилактики и лечения заболеваний кожи |
| RU2437671C1 (ru) * | 2010-06-11 | 2011-12-27 | Сергей Владимирович Енгашев | Способ очистки экстракта зеленого чая, лекарственное средство на его основе и способ профилактики и лечения заболеваний кожи |
| CN110237447B (zh) | 2013-09-27 | 2021-11-02 | 梅维昂医疗系统股份有限公司 | 粒子治疗系统 |
| WO2015090853A1 (en) * | 2013-12-20 | 2015-06-25 | Unilever N.V. | Sunless tanning |
| US10675487B2 (en) | 2013-12-20 | 2020-06-09 | Mevion Medical Systems, Inc. | Energy degrader enabling high-speed energy switching |
| US9962560B2 (en) | 2013-12-20 | 2018-05-08 | Mevion Medical Systems, Inc. | Collimator and energy degrader |
| US9661736B2 (en) | 2014-02-20 | 2017-05-23 | Mevion Medical Systems, Inc. | Scanning system for a particle therapy system |
| US10786689B2 (en) | 2015-11-10 | 2020-09-29 | Mevion Medical Systems, Inc. | Adaptive aperture |
| CN109803723B (zh) | 2016-07-08 | 2021-05-14 | 迈胜医疗设备有限公司 | 一种粒子疗法系统 |
| US11103730B2 (en) | 2017-02-23 | 2021-08-31 | Mevion Medical Systems, Inc. | Automated treatment in particle therapy |
| JP6940676B2 (ja) | 2017-06-30 | 2021-09-29 | メビオン・メディカル・システムズ・インコーポレーテッド | リニアモーターを使用して制御される構成可能コリメータ |
| WO2020185544A1 (en) | 2019-03-08 | 2020-09-17 | Mevion Medical Systems, Inc. | Delivery of radiation by column and generating a treatment plan therefor |
| IT201900003843A1 (it) * | 2019-03-15 | 2020-09-15 | Lo Li Pharma Srl | Trattamento di fibromi con vitamina D e un agente come l'epigallocatechina gallato (EGCG) |
| WO2025077883A1 (zh) * | 2023-10-13 | 2025-04-17 | 恩康药业科技(广州)有限公司 | 治疗和/或预防皮肤癌或其癌前病变的化合物及方法 |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002775A (en) | 1973-07-09 | 1977-01-11 | Kabara Jon J | Fatty acids and derivatives of antimicrobial agents |
| JPS55105677A (en) | 1979-02-07 | 1980-08-13 | Norin Suisansyo Chiyagiyou Shikenjo | Production of catechins |
| US4306568A (en) * | 1979-12-04 | 1981-12-22 | Torre Douglas P | Method and apparatus for congelation cryometry in cryosurgery |
| EP0087161A3 (en) | 1982-02-24 | 1984-04-04 | Key Pharmaceuticals, Inc. | Isopropylmyristate 4-alkyl-2,6-(bis-tert-butyl)-phenol medicament |
| JPS59219384A (ja) | 1983-05-30 | 1984-12-10 | Mitsui Norin Kk | 天然抗酸化剤の製造方法 |
| JPS6013780A (ja) | 1983-07-05 | 1985-01-24 | Mitsui Norin Kk | 茶カテキン類の製造方法 |
| JPS61238728A (ja) | 1985-04-16 | 1986-10-24 | Mitsui Norin Kk | 茶葉抽出物と活性水酸化アルミニウムとの抗潰瘍性複合体 |
| US4672810A (en) | 1985-10-15 | 1987-06-16 | Marlowe Christian P | Hydraulic transmission device and method of using it |
| SE462894B (sv) | 1985-10-28 | 1990-09-17 | Biogram Ab | Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning |
| US4863970A (en) | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
| US5204089A (en) | 1989-08-30 | 1993-04-20 | Mitsui Norin Co., Ltd. | Method of preventing the formation or aggrevation of dental plaque and method for reducing cariogenesis |
| JP2727471B2 (ja) | 1989-09-14 | 1998-03-11 | 三井農林株式会社 | インフルエンザウィルス感染予防剤 |
| JP2888554B2 (ja) | 1989-09-20 | 1999-05-10 | 三井農林株式会社 | マイコプラズマ感染予防剤 |
| US5318986A (en) | 1989-10-19 | 1994-06-07 | Mitsui Norin Co., Ltd. | Method of inhibiting the activity of α-amylase |
| US5063787A (en) * | 1989-11-22 | 1991-11-12 | General Electric Company | Venturi arrangement |
| US5358713A (en) | 1990-02-23 | 1994-10-25 | Mitsui Norin Co., Ltd. | Method of preventing the transmission of infection caused by methicillin-resistant Staphylococcus aureus |
| JP3019996B2 (ja) | 1990-03-01 | 2000-03-15 | 三井農林株式会社 | 白癬治療剤 |
| JPH04253918A (ja) | 1991-02-05 | 1992-09-09 | Mitsui Norin Kk | 血糖上昇抑制剤 |
| US5303486A (en) * | 1992-05-04 | 1994-04-19 | Dell Gay D | Quilting hoop |
| CA2136614C (en) | 1992-06-08 | 2002-10-22 | Petrus Johannes Meyer | Nitrous oxide containing dermatological composition |
| US5306486A (en) | 1993-03-01 | 1994-04-26 | Elizabeth Arden Co., Division Of Conopco, Inc. | Cosmetic sunscreen composition containing green tea and a sunscreen |
| JP3333584B2 (ja) | 1993-04-19 | 2002-10-15 | 三井農林株式会社 | 歯質の耐酸性強化組成物 |
| US5670154A (en) | 1994-01-10 | 1997-09-23 | Mitsui Norin Co., Ltd. | Reducing tyrosinase activity |
| FR2718022B1 (fr) | 1994-04-01 | 1996-04-26 | Roussel Uclaf | Compositions cosmétiques ou dermatologiques et leur préparation. |
| IL115156A (en) | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
| JP2718653B2 (ja) | 1995-01-31 | 1998-02-25 | 日本配合飼料株式会社 | 新規卵および卵質改良方法 |
| IT1275905B1 (it) | 1995-03-14 | 1997-10-24 | Indena Spa | Frazioni polifenoliche di te', loro uso e formulazioni che le contengono |
| GB2300578B (en) | 1995-05-11 | 1998-01-14 | Matsushita Seiko Kk | Gargling cup,antiviral mask,antiviral filter,antifungal,antibacterial,and antiviral filter air cleaner and air-cleaner-humidifier |
| US5888527A (en) | 1995-05-11 | 1999-03-30 | Matsushita Seiko Co., Ltd. | Gargling cup, antiviral mask, antiviral filter, antifungal, antibacterial, and antiviral filter air cleaner and air-cleaner humidifier |
| JPH09132532A (ja) | 1995-09-06 | 1997-05-20 | Mitsui Norin Kk | 抗生物質の抗菌力増強方法 |
| US6127393A (en) | 1995-12-29 | 2000-10-03 | Novactyl, Inc. | Antiproliferative, antiinfective, antiinflammatory, autologous immunization agent and method |
| US5804567A (en) | 1996-07-18 | 1998-09-08 | Cancer Institute (Hospital), Chinese Academy Of Medical Sciences | Method of increasing the effectiveness of anti-metabolites |
| US6337320B1 (en) * | 1996-10-11 | 2002-01-08 | Thione International, Inc. | Reparatives for ultraviolet radiation skin damage |
| ATE442844T1 (de) | 1996-11-14 | 2009-10-15 | Lipomedica Ehf | Topische zusammensetzungen enthaltend als therapeutisch aktiven wirkstoff ein monoglycerid zur behandlung von schleimhautinfektionen |
| US5968973A (en) | 1996-11-18 | 1999-10-19 | Cancer Institute (Hospital), Chinese Academy Of Medical Sciences | Method for treating hyperplasia |
| JP3213557B2 (ja) | 1996-11-18 | 2001-10-02 | 三井農林株式会社 | 茶カテキンを有効成分として含有する尖圭コンジローマ治療剤 |
| US6197808B1 (en) * | 1996-11-18 | 2001-03-06 | Cancer Instititute (Hospital), Chinese Academy Of Medical Sciences | Methods for treating hyperplasia |
| AU6436998A (en) * | 1997-02-20 | 1998-09-09 | Yale University | Therapeutic uses for antioxidants |
| JP3202938B2 (ja) | 1997-03-18 | 2001-08-27 | 三井農林株式会社 | チューインガム及びその製造法 |
| US5910308A (en) | 1997-03-19 | 1999-06-08 | Sante International Inc. | Herbal extract composition containing gynostemma pentaphyllum, crataegus pinnatifida and camellia sinensis |
| US6372234B1 (en) | 1997-05-27 | 2002-04-16 | Sembiosys Genetics Inc. | Products for topical applications comprising oil bodies |
| AU1289899A (en) | 1997-10-31 | 1999-05-24 | Arch Development Corporation | Methods and compositions for regulation of 5-alpha reductase activity |
| US6696484B2 (en) | 1997-10-31 | 2004-02-24 | University Of Chicago Office Of Technology And Intellectual Property | Method and compositions for regulation of 5-alpha reductase activity |
| US20020006447A1 (en) | 1998-04-21 | 2002-01-17 | Mitsui Norin Co., Ltd. | Anti-chlamydia agent |
| KR100417703B1 (ko) | 1998-04-21 | 2004-02-11 | 미쓰이 노린 가부시키가이샤 | 항클라미디아제 |
| DE19827624A1 (de) | 1998-06-20 | 1999-12-23 | Beiersdorf Ag | Verwendung von einem mit einem Gehalt an Catecinen oder einem Gehalt an Extrakt von grünem Tee in kosmetischen Zubereitungen zur Bräunung der Haut |
| SE9803929D0 (sv) | 1998-11-18 | 1998-11-18 | Medivir Ab | Antiviral formulation |
| KR100319973B1 (ko) | 1998-12-05 | 2002-04-22 | 이인수 | 녹차카테킨을 유효성분으로 하는 자궁경부 상피내종양 예방 또는 치료제 조성물 |
| US6210679B1 (en) * | 1999-01-07 | 2001-04-03 | Hauser, Inc. | Method for isolation of caffeine-free catechins from green tea |
| DE19962369A1 (de) | 1999-12-23 | 2001-06-28 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Catechinen oder einem Gehalt an Extrakt von grünem Tee und einem weiteren Gehalt an Ascorbinsäure |
| US6248341B1 (en) | 2000-01-14 | 2001-06-19 | Color Access, Inc. | Method of treating topical angiogenesis-related disorders |
| US20020031535A1 (en) * | 2000-09-11 | 2002-03-14 | Sheffield Felix H. | Topical formulation to treat skin disorders |
| US6538023B1 (en) * | 2000-09-15 | 2003-03-25 | Tsuyoshi Ohnishi | Therapeutic uses of green tea polyphenols for sickle cell disease |
| US6713506B2 (en) * | 2000-10-11 | 2004-03-30 | University Of South Florida | Tea polyphenol esters and analogs thereof for cancer prevention and treatment |
| ATE417611T1 (de) | 2001-11-19 | 2009-01-15 | Medigene Ag | Arzneimittel zur behandlung von viralen haut- und tumorerkrankungen |
| US20030143165A1 (en) * | 2002-01-25 | 2003-07-31 | Allan Evans | NSAID-containing topical formulations that demonstrate chemopreventive activity |
| US20030166583A1 (en) * | 2002-02-22 | 2003-09-04 | Oliver Yoa-Pu Hu | Dermal cytochrome P450 1A inhibitors and enhancers |
| US6723750B2 (en) * | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
| BRPI0204130B8 (pt) | 2002-09-18 | 2021-05-25 | Fund De Amparo A Pesquisa Do Estado De Sao Paulo Fapesp | composição gel à base de extrato de pothomorphe umbellata, seus usos e método cosmético não-terapêutico. |
| US20040191842A1 (en) | 2002-12-10 | 2004-09-30 | Medical College Of Georgia Research Institute, Inc. | Chemopreventive and therapeutic aspects of polyphenolic compositions and assays |
| US6817511B2 (en) * | 2002-12-16 | 2004-11-16 | Dana Corporation | Method for joining axle components |
| WO2004080293A2 (en) | 2003-03-13 | 2004-09-23 | 3M Innovative Properties Company | Methods for diagnosing skin lesions |
| US20050079235A1 (en) | 2003-10-09 | 2005-04-14 | Eggert Stockfleth | Use of a polyphenol for the treatment of actinic keratosis |
-
2004
- 2004-10-08 BR BRPI0415215A patent/BRPI0415215B8/pt not_active IP Right Cessation
- 2004-10-08 US US10/574,422 patent/US7910138B2/en not_active Expired - Fee Related
- 2004-10-08 EP EP04790231A patent/EP1684780B1/en not_active Expired - Lifetime
- 2004-10-08 AR ARP040103652A patent/AR045865A1/es unknown
- 2004-10-08 WO PCT/EP2004/011300 patent/WO2005037300A1/en not_active Ceased
- 2004-10-08 AU AU2004281525A patent/AU2004281525B2/en not_active Expired
- 2004-10-08 ZA ZA200602544A patent/ZA200602544B/en unknown
- 2004-10-08 NZ NZ546323A patent/NZ546323A/xx not_active IP Right Cessation
- 2004-10-08 ES ES04790231T patent/ES2391561T3/es not_active Expired - Lifetime
- 2004-10-08 CA CA2541405A patent/CA2541405C/en not_active Expired - Lifetime
- 2004-10-08 EP EP10012395A patent/EP2292226A3/en not_active Ceased
- 2004-10-08 RU RU2006115603/15A patent/RU2366447C2/ru active
- 2004-10-08 MX MXPA06003404A patent/MXPA06003404A/es active IP Right Grant
-
2006
- 2006-03-21 IL IL174434A patent/IL174434A0/en active IP Right Grant
-
2011
- 2011-03-18 US US13/051,593 patent/US8455022B2/en not_active Expired - Fee Related
-
2013
- 2013-05-07 US US13/888,949 patent/US9060998B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20110166219A1 (en) | 2011-07-07 |
| CA2541405C (en) | 2014-07-29 |
| EP2292226A2 (en) | 2011-03-09 |
| EP1684780B1 (en) | 2012-07-25 |
| US9060998B2 (en) | 2015-06-23 |
| ES2391561T3 (es) | 2012-11-27 |
| EP1684780A1 (en) | 2006-08-02 |
| NZ546323A (en) | 2009-04-30 |
| AU2004281525B2 (en) | 2010-01-28 |
| IL174434A0 (en) | 2006-08-01 |
| US20070059387A1 (en) | 2007-03-15 |
| AU2004281525A1 (en) | 2005-04-28 |
| US8455022B2 (en) | 2013-06-04 |
| BRPI0415215B1 (pt) | 2021-02-23 |
| RU2366447C2 (ru) | 2009-09-10 |
| WO2005037300A1 (en) | 2005-04-28 |
| US7910138B2 (en) | 2011-03-22 |
| CA2541405A1 (en) | 2005-04-28 |
| MXPA06003404A (es) | 2006-06-27 |
| AR045865A1 (es) | 2005-11-16 |
| BRPI0415215B8 (pt) | 2021-05-25 |
| US20130245113A1 (en) | 2013-09-19 |
| RU2006115603A (ru) | 2007-11-27 |
| EP2292226A3 (en) | 2011-08-10 |
| ZA200602544B (en) | 2007-06-27 |
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