BRPI0416128A - dispositivo de dispensação de fluido, e, kit de partes - Google Patents

dispositivo de dispensação de fluido, e, kit de partes

Info

Publication number
BRPI0416128A
BRPI0416128A BRPI0416128-9A BRPI0416128A BRPI0416128A BR PI0416128 A BRPI0416128 A BR PI0416128A BR PI0416128 A BRPI0416128 A BR PI0416128A BR PI0416128 A BRPI0416128 A BR PI0416128A
Authority
BR
Brazil
Prior art keywords
dispensing device
fluid dispensing
fluid
parts kit
actuation
Prior art date
Application number
BRPI0416128-9A
Other languages
English (en)
Inventor
Michael Birsha Davies
Mark Graham Hedley
Margot Jean Jones
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0325629A external-priority patent/GB0325629D0/en
Priority claimed from GBGB0405477.1A external-priority patent/GB0405477D0/en
Priority claimed from GB0420539A external-priority patent/GB0420539D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BRPI0416128A publication Critical patent/BRPI0416128A/pt
Publication of BRPI0416128B1 publication Critical patent/BRPI0416128B1/pt
Publication of BRPI0416128B8 publication Critical patent/BRPI0416128B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1052Actuation means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1052Actuation means
    • B05B11/1056Actuation means comprising rotatable or articulated levers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1059Means for locking a pump or its actuation means in a fixed position
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/38Details of the container body
    • B65D83/384Details of the container body the container body being an aerosol container located in an outer shell or in an external container
    • B65D83/386Details of the container body the container body being an aerosol container located in an outer shell or in an external container actuation occurring by moving the aerosol container relative to the outer shell or external container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0037Containers
    • B05B11/0038Inner container disposed in an outer shell or outer casing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nozzles (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)

Abstract

DISPOSITIVO DE DISPENçãO DE FLUIDO, E, KIT DE PARTES. é revelado um dispositivo de dispensação de fluido (5, 105, 205, 305, 405, 505) para dispensar uma formulação de medicamento na forma de fluido com uma viscosidade de 10 a 2.000 mPa.s, e compreende um alojamento (9, 109, 209, 309, 409, 509) e um dispositivo de descarga de fluido (8, 108, 208, 308, 408, 508) arranjado para ser atuado por uma ou mais alavancas (20, 21; 120, 121; 170; 220, 221; 321; 420, 421; 520) para causar a atuação de uma bomba que forma parte do dispositivo de dispensação de fluido. Um meio de pré-carga (28; 28; 28; 39,40; 41, 42, 44; 144, 47a 47b, 15, 152, 153; 224, 227; 342; 424x, 446; 425a, 427, 428; 560, 561) é usado para impedir a atuação da bomba até que uma força pré-determinada seja aplicada em cada alavanca de magnitude suficiente para garantir a produção de um jato eficiente bem desenvolvido pelo dispositivo de dispensação de fluido.
BRPI0416128A 2003-11-03 2004-11-02 dispositivo de dispensação de fluido BRPI0416128B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0325629.4 2003-11-03
GB0325629A GB0325629D0 (en) 2003-11-03 2003-11-03 A fluid dispensing device
GB0405477.1 2004-03-11
GBGB0405477.1A GB0405477D0 (en) 2004-03-11 2004-03-11 A fluid dispensing device
GB0420539A GB0420539D0 (en) 2004-09-17 2004-09-17 A fluid dispensing device
GB0420539.9 2004-09-17
PCT/GB2004/004626 WO2005044354A1 (en) 2003-11-03 2004-11-02 A fluid dispensing device

Publications (3)

Publication Number Publication Date
BRPI0416128A true BRPI0416128A (pt) 2007-01-02
BRPI0416128B1 BRPI0416128B1 (pt) 2018-08-07
BRPI0416128B8 BRPI0416128B8 (pt) 2021-06-22

Family

ID=36501884

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416128A BRPI0416128B8 (pt) 2003-11-03 2004-11-02 dispositivo de dispensação de fluido

Country Status (13)

Country Link
US (2) US8752543B2 (pt)
EP (1) EP1699512B1 (pt)
JP (1) JP4641526B2 (pt)
CN (2) CN102028994B (pt)
AU (2) AU2004287261B8 (pt)
BR (1) BRPI0416128B8 (pt)
CA (1) CA2544378A1 (pt)
CY (1) CY1113086T1 (pt)
DK (1) DK1699512T3 (pt)
ES (1) ES2388434T3 (pt)
PL (1) PL1699512T3 (pt)
PT (1) PT1699512E (pt)
WO (1) WO2005044354A1 (pt)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011109883A1 (en) * 2010-03-08 2011-09-15 Victor Esteve Medicine dispensing device
DE202012007318U1 (de) 2011-10-27 2012-08-29 Victor Esteve Medikamentenabgabevorr.chtung

Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ535873A (en) * 2002-05-09 2006-07-28 Glaxo Group Ltd A fluid dispensing device
GB0217802D0 (en) * 2002-08-01 2002-09-11 Glaxo Group Ltd A fluid dispensing device
GB0405477D0 (en) * 2004-03-11 2004-04-21 Glaxo Group Ltd A fluid dispensing device
PL1699512T3 (pl) 2003-11-03 2012-11-30 Glaxo Group Ltd Urządzenie do dozowania płynów
GB0418045D0 (en) 2004-08-12 2004-09-15 Glaxo Group Ltd Compounds
GB0507224D0 (en) 2005-04-09 2005-05-18 Glaxo Group Ltd A fluid dispensing device
SE529956C2 (sv) * 2005-07-12 2008-01-15 Medux Ab Sprejanordning, metod för sprejning samt sätt för tillverkning av anordning
GB0518770D0 (en) * 2005-09-14 2005-10-26 Glaxo Group Ltd A closure for a dispensing device
GB0521563D0 (en) 2005-10-21 2005-11-30 Glaxo Group Ltd Novel compounds
GB2434753B (en) 2005-11-22 2008-03-12 Bespak Plc Aerosol dispensing apparatus
WO2007062205A2 (en) * 2005-11-23 2007-05-31 S. C. Johnson & Son, Inc. Hand-held spray device
KR20090003349A (ko) 2006-04-20 2009-01-09 글락소 그룹 리미티드 화합물
GB2448839B (en) 2006-05-26 2009-05-27 Consort Medical Plc Improvements in or relating to dispensing apparatus
GB0610541D0 (en) 2006-05-26 2006-07-05 Bespak Plc Improvements in or relating to dispensing apparatus
GB0611587D0 (en) 2006-06-12 2006-07-19 Glaxo Group Ltd Novel compounds
CA2659539A1 (en) 2006-08-01 2008-02-07 Glaxo Group Limited Pyrazolo[3,4-b]pyridine compounds, and their use as pde4 inhibitors
CA2661132A1 (en) * 2006-08-22 2008-02-28 Glaxo Group Limited Drug dispenser
WO2008110584A2 (en) * 2007-03-13 2008-09-18 Glaxo Group Limited Drug dispenser
DE102007016503A1 (de) * 2007-03-26 2008-10-02 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
EP2197524B1 (en) 2007-08-21 2016-09-28 Glaxo Group Limited Drug dispenser
TW201513903A (zh) * 2007-11-29 2015-04-16 Glaxo Group Ltd 施配裝置
JP5502077B2 (ja) 2008-06-05 2014-05-28 グラクソ グループ リミテッド 新規な化合物
ES2566339T3 (es) 2008-06-05 2016-04-12 Glaxo Group Limited Derivados de 4-carboxamida indazol útiles como inhibidores de PI3-quinasas
FR2932399B1 (fr) * 2008-06-17 2011-10-28 Valois Sas Dispositif de distribution de produit fluide
KR101616396B1 (ko) 2008-08-11 2016-04-28 글락소스미스클라인 엘엘씨 신규의 아데닌 유도체
UA103195C2 (uk) 2008-08-11 2013-09-25 Глаксосмитклайн Ллк Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
EA201100114A1 (ru) 2008-08-11 2011-10-31 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Производные пурина для применения в лечении аллергических, воспалительных и инфекционных заболеваний
ES2433109T3 (es) 2009-01-13 2013-12-09 Glaxo Group Limited Derivados de pirimidin-carboxamida como inhibidores de la Syk cinasa
WO2010094643A1 (en) 2009-02-17 2010-08-26 Glaxo Group Limited Quinoline derivatives and their uses for rhinitis and urticaria
US8524751B2 (en) 2009-03-09 2013-09-03 GlaxoSmithKline Intellecutual Property Development 4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
EP2408769A1 (en) 2009-03-17 2012-01-25 Glaxo Group Limited Pyrimidine derivatives used as itk inhibitors
JP2012520685A (ja) 2009-03-19 2012-09-10 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いたGATA結合タンパク質3(GATA3)遺伝子発現のRNA干渉媒介性阻害
EP2408916A2 (en) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010107958A1 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EA201171144A1 (ru) 2009-03-19 2012-04-30 Мерк Шарп Энд Домэ Корп. ОПОСРЕДОВАННОЕ РНК-ИНТЕРФЕРЕНЦИЕЙ ИНГИБИРОВАНИЕ ЭКСПРЕССИИ ГЕНА ГОМОЛОГА 1 BTB И CNC, ОСНОВНОГО ФАКТОРА ТРАНСКРИПЦИИ С ЛЕЙЦИНОВОЙ МОЛНИЕЙ 1 (Bach1) С ИСПОЛЬЗОВАНИЕМ МАЛОЙ ИНТЕРФЕРИРУЮЩЕЙ НУКЛЕИНОВОЙ КИСЛОТЫ (миНК)
JP2012521760A (ja) 2009-03-27 2012-09-20 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いたアポトーシスシグナル調節キナーゼ1(ASK1)遺伝子発現のRNA干渉媒介性阻害
KR20110138223A (ko) 2009-03-27 2011-12-26 머크 샤프 앤드 돔 코포레이션 짧은 간섭 핵산 (siNA)을 사용한 세포간 부착 분자 1 (ICAM-1) 유전자 발현의 RNA 간섭 매개 억제
US20120022142A1 (en) 2009-03-27 2012-01-26 Merck Sharp & Dohme Corp. RNA Interference Mediated Inhibition of Signal Transducer and Activator of Transcription 1 (STAT1) Gene Expression Using Short Interfering Nucleic Acid (siNA)
US20120022143A1 (en) 2009-03-27 2012-01-26 Merck Sharp & Dohme Corp RNA Interference Mediated Inhibition of the Thymic Stromal Lymphopoietin (TSLP) Gene Expression Using Short Interfering Nucliec Acid (siNA)
WO2010111468A2 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
EP2421834A1 (en) 2009-04-24 2012-02-29 Glaxo Group Limited Pyrazole and triazole carboxamides as crac channel inhibitors
US20100273744A1 (en) 2009-04-24 2010-10-28 Paul Martin Gore Compounds
CN102459253B (zh) 2009-04-30 2015-03-25 葛兰素集团有限公司 作为pi3-激酶抑制剂的*唑取代的吲唑化合物
DE102009049902A1 (de) * 2009-10-13 2011-04-14 Ing. Erich Pfeiffer Gmbh Austragvorrichtung
GB0919431D0 (en) 2009-11-05 2009-12-23 Glaxosmithkline Llc Novel compounds
KR20120097508A (ko) 2009-11-05 2012-09-04 글락소스미스클라인 엘엘씨 벤조디아제핀 브로모도메인 억제제
WO2011054851A1 (en) 2009-11-05 2011-05-12 Glaxosmithkline Llc Novel process
MY160456A (en) 2009-11-05 2017-03-15 Glaxosmithkline Llc Benzodiazepine bromodomain inhibitor
GB0919423D0 (en) 2009-11-05 2009-12-23 Glaxosmithkline Llc Novel compounds
GB0919432D0 (en) 2009-11-05 2009-12-23 Glaxosmithkline Llc Use
GB0919434D0 (en) 2009-11-05 2009-12-23 Glaxosmithkline Llc Novel compounds
GB0919426D0 (en) 2009-11-05 2009-12-23 Glaxosmithkline Llc Novel compounds
US20120238559A1 (en) 2009-12-03 2012-09-20 Glaxo Group Limited Novel compounds
EP2507223A1 (en) 2009-12-03 2012-10-10 Glaxo Group Limited Benzpyrazole derivatives as inhibitors of p13 kinases
WO2011067366A1 (en) 2009-12-03 2011-06-09 Glaxo Group Limited Indazole derivatives as pi 3 - kinase inhibitors
MA33926B1 (fr) 2009-12-17 2013-01-02 Merck Sharp & Dohme Aminopyrimidines en tant qu'inhibiteurs de la syk
ES2652492T3 (es) * 2009-12-23 2018-02-02 Becton Dickinson & Company Dispositivo de administración de medicamento monodosis por vía nasal
EA021048B1 (ru) 2010-02-10 2015-03-31 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Малеат 6-амино-2-{[(1s)-1-метилбутил]окси}-9-[5-(1-пиперидинил)пентил]-7,9-дигидро-8н-пурин-8-она
US8575340B2 (en) 2010-02-10 2013-11-05 Glaxosmithkline Llc Purine derivatives and their pharmaceutical uses
WO2011110575A1 (en) 2010-03-11 2011-09-15 Glaxo Group Limited Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
GB201007203D0 (en) 2010-04-29 2010-06-16 Glaxo Group Ltd Novel compounds
US9211994B2 (en) * 2010-05-21 2015-12-15 S.C. Johnson & Son, Inc. Shroud and dispensing system for a handheld container
US9051108B2 (en) * 2010-05-21 2015-06-09 S.C. Johnson & Son, Inc. Shroud and dispensing system for a handheld container
US8578942B2 (en) * 2010-05-25 2013-11-12 British American Tobacco (Investments) Limited Aerosol generator
US8950395B2 (en) 2010-05-25 2015-02-10 Nicoventures Holdings Limited Aerosol generator
US8689786B2 (en) 2010-05-25 2014-04-08 British American Tobacco (Investments) Limited Aerosol generator
US9085582B2 (en) 2010-06-22 2015-07-21 Glaxosmithkline Llc Benzotriazolodiazepine compounds inhibitors of bromodomains
US8651046B1 (en) * 2010-07-23 2014-02-18 The Boeing Company Robotic sealant and end effector
US8459508B2 (en) 2010-07-30 2013-06-11 S.C. Johnson & Son, Inc. Shroud for a dispenser
US20120024894A1 (en) * 2010-07-30 2012-02-02 Westphal Nathan R Dispenser
MX2013001200A (es) * 2010-07-30 2013-05-09 Johnson & Son Inc S C Dispensador.
CN107090456B (zh) 2010-08-02 2022-01-18 瑟纳治疗公司 使用短干扰核酸的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1基因表达的抑制
JP2013537423A (ja) 2010-08-17 2013-10-03 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いたB型肝炎ウイルス(HBV)遺伝子発現のRNA干渉媒介性阻害
WO2012025473A1 (en) 2010-08-24 2012-03-01 Glaxo Group Limited Cc.chemokine receptor 4 antagonists
WO2012025474A1 (en) 2010-08-24 2012-03-01 Glaxo Group Limited Indazole compounds
WO2012027467A1 (en) 2010-08-26 2012-03-01 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2 (PHD2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2012032065A1 (en) 2010-09-08 2012-03-15 Glaxo Group Limited Indazole derivatives for use in the treatment of influenza virus infection
JP5965402B2 (ja) 2010-09-08 2016-08-03 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited N−[5−[4−(5−{[(2r,6s)−2,6−ジメチル−4−モルホリニル]メチル}−1,3−オキサゾール−2−イル)−1h−インダゾール−6−イル]−2−(メチルオキシ)−3−ピリジニル]メタンスルホンアミドの多形体および塩
WO2012035055A1 (en) 2010-09-17 2012-03-22 Glaxo Group Limited Novel compounds
WO2012045729A1 (en) 2010-10-05 2012-04-12 Glaxo Group Limited Imidazo [1, 2 -a] pyridine and pyrazolo [1, 5 -a] pyridine derivatives as trpv1 antagonists
EP2630126B1 (en) 2010-10-21 2015-01-07 Glaxo Group Limited Pyrazole compounds acting against allergic, immune and inflammatory conditions
EP2630127A1 (en) 2010-10-21 2013-08-28 Glaxo Group Limited Pyrazole compounds acting against allergic, inflammatory and immune disorders
GB201018124D0 (en) 2010-10-27 2010-12-08 Glaxo Group Ltd Polymorphs and salts
DK2632472T3 (en) 2010-10-29 2018-03-19 Sirna Therapeutics Inc RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
WO2012072512A1 (en) 2010-11-29 2012-06-07 Glaxo Group Limited N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists
GB201104153D0 (en) 2011-03-11 2011-04-27 Glaxo Group Ltd Novel compounds
US20140005188A1 (en) 2011-03-11 2014-01-02 Glaxo Group Limited Pyrido[3,4-b]pyrazine derivatives as syk inhibitors
FR2973011B1 (fr) * 2011-03-21 2013-04-26 Valois Sas Dispositif de distribution de produit fluide a actionnement lateral.
GB201106799D0 (en) 2011-04-21 2011-06-01 Glaxosmithkline Llc Novel compounds
GB201106750D0 (en) 2011-04-21 2011-06-01 Glaxosmithkline Llc Novel compounds
GB201106743D0 (en) 2011-04-21 2011-06-01 Glaxosmithkline Llc Novel compounds
BR112013028430A2 (pt) 2011-05-04 2017-08-01 Merck Sharp & Dohme composto, composição farmacêutica, método para tratar uma doença ou condição mediada por tirosina quinase do baço (syk), e, uso de uma quantidade terapeuticamente eficiente do composto
GB201107325D0 (en) 2011-05-04 2011-06-15 Glaxosmithkline Llc Novel compounds
WO2012154518A1 (en) 2011-05-10 2012-11-15 Merck Sharp & Dohme Corp. Bipyridylaminopyridines as syk inhibitors
WO2012153289A1 (en) * 2011-05-12 2012-11-15 Koninklijke Philips Electronics N.V. Patient interface device including a pneumatically adjusting forehead support
EP2548877A1 (en) 2011-07-19 2013-01-23 MSD Oss B.V. 4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors
PL2734186T3 (pl) 2011-07-22 2019-01-31 Glaxosmithkline Llc Kompozycja
GB201114103D0 (en) 2011-08-17 2011-09-28 Glaxosmithkline Llc Novel compounds
US8987456B2 (en) 2011-10-05 2015-03-24 Merck Sharp & Dohme Corp. 3-pyridyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
KR101496970B1 (ko) * 2012-04-20 2015-03-02 (주)연우 비강세척수 분사용기
EP2844261B1 (en) 2012-05-02 2018-10-17 Sirna Therapeutics, Inc. SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
FR2991185B1 (fr) * 2012-05-31 2015-06-26 Valois Sas Dispositif de distribution de produit fluide.
EP2863916B1 (en) 2012-06-22 2018-07-18 Merck Sharp & Dohme Corp. Substituted pyridine spleen tyrosine kinase (syk) inhibitors
WO2013192088A1 (en) 2012-06-22 2013-12-27 Merck Sharp & Dohme Corp. SUBSTITUTED DIAZINE AND TRIAZINE SPLEEN TYROSINE KINASE (Syk) INHIBITORS
CA2879341C (en) 2012-07-26 2019-06-11 Glaxo Group Limited 2- (azaindol-2-yl) benzimidazoles as pad4 inhibitors
CN104903213B (zh) * 2012-11-14 2017-11-24 维实洛克分配系统公司 儿童安全泵
DE102012023216A1 (de) * 2012-11-28 2014-05-28 Meadwestvaco Calmar Gmbh Austragvorrichtung für ein fluides Medium
CN104903307A (zh) 2012-12-06 2015-09-09 默沙东公司 二硫化物屏蔽的前体药物组合物和方法
DE102013000794B4 (de) 2013-01-17 2019-10-02 WestRock Dispensing Systems Hemer GmbH Austragvorrichtung für ein fluides Medium
TW201441234A (zh) 2013-01-23 2014-11-01 Merck Sharp & Dohme Btk抑制劑
WO2014113942A1 (en) 2013-01-23 2014-07-31 Merck Sharp & Dohme Corp. Btk inhibitors
KR20150128842A (ko) 2013-03-14 2015-11-18 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 브로모도메인 억제제로서의 퓨로피리딘
WO2014140076A1 (en) 2013-03-14 2014-09-18 Glaxosmithkline Intellectual Property (No.2) Limited 2,3-disubstituted 1 -acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors
EP2983773B1 (en) * 2013-03-14 2018-03-07 Trudell Medical International Metered dose inhaler applicator
RU2645451C2 (ru) * 2013-03-22 2018-02-26 Олтриа Клайент Сервисиз Ллк. Электронное курительное изделие
GB201305668D0 (en) 2013-03-28 2013-05-15 Glaxosmithkline Ip Dev Ltd Avs6 Integrin Antagonists
EP2988749B1 (en) 2013-04-26 2019-08-14 Merck Sharp & Dohme Corp. Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors
KR20160060100A (ko) 2013-09-22 2016-05-27 칼리토르 사이언시즈, 엘엘씨 치환된 아미노피리미딘 화합물 및 이용 방법
WO2015055691A1 (en) 2013-10-17 2015-04-23 Glaxosmithkline Intellectual Property Development Limited Pi3k inhibitor for treatment of respiratory disease
EP3057587A1 (en) 2013-10-17 2016-08-24 GlaxoSmithKline Intellectual Property Development Limited Pi3k inhibitor for treatment of respiratory disease
GB2519782A (en) * 2013-10-30 2015-05-06 British American Tobacco Co An inhaler
EP3082811B1 (en) 2013-12-20 2020-01-15 Merck Sharp & Dohme Corp. Btk inhibitors
EP3083559B1 (en) 2013-12-20 2021-03-10 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
US9670196B2 (en) 2013-12-20 2017-06-06 Merck Sharp & Dohme Corp. Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors
EP3082809B1 (en) 2013-12-20 2021-01-20 Merck Sharp & Dohme Corp. Btk inhibitors
JP6452711B2 (ja) 2014-02-20 2019-01-16 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited ヒトインターフェロンの誘導物質としてのピロロ[3,2]ピリミジン誘導体
JP2017533925A (ja) 2014-11-13 2017-11-16 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム アレルギー性疾患又は他の炎症状態の治療に有用なアデニン誘導体
WO2016106629A1 (en) 2014-12-31 2016-07-07 Merck Sharp & Dohme Corp. Btk inhibitors
WO2016106626A1 (en) 2014-12-31 2016-07-07 Merck Sharp & Dohme Corp. Imidazopyrazine analogs with 3-tertiary carbon substitutions as btk inhibitors
WO2016106628A1 (en) 2014-12-31 2016-07-07 Merck Sharp & Dohme Corp. Btk inhibitors
WO2016106624A1 (en) 2014-12-31 2016-07-07 Merck Sharp & Dohme Corp. Tertiary alcohol imidazopyrazine btk inhibitors
WO2016106623A1 (en) 2014-12-31 2016-07-07 Merck Sharp & Dohme Corp. Benzamide imidazopyrazine btk inhibitors
AU2016264958B2 (en) 2015-05-21 2020-10-29 Glaxosmithkline Intellectual Property Development Limited Benzoimidazole derivatives as PAD4 inhibitors
GB201516243D0 (en) 2015-09-14 2015-10-28 Glaxosmithkline Ip Dev Ltd Novel compounds
AU2016326864A1 (en) 2015-09-22 2018-03-22 Glaxosmithkline Intellectual Property (No.2) Limited Pyridinone dicarboxamide for use as bromodomain inhibitors
CA3006930A1 (en) 2015-12-03 2017-06-08 Glaxosmithkline Intellectual Property Development Limited Cyclic purine dinucleotides as modulators of sting
GB201602527D0 (en) 2016-02-12 2016-03-30 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201604680D0 (en) 2016-03-21 2016-05-04 Glaxosmithkline Ip Dev Ltd Chemical Compounds
KR20180132680A (ko) 2016-04-07 2018-12-12 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 브로모도메인 억제제로서 벤조[b]푸란
JP6954921B2 (ja) 2016-04-07 2021-10-27 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited ブロモドメイン阻害薬としてのピリジル誘導体
FR3049880B1 (fr) * 2016-04-08 2020-10-23 Aptar France Sas Ensemble de distribution de produit fluide.
DE102016206084B4 (de) * 2016-04-12 2018-04-26 Henkel Ag & Co. Kgaa Vorrichtung zum Herausdrücken eines Stoffes aus einer verformbaren Tube
AU2017269673A1 (en) 2016-05-24 2018-11-22 Glaxosmithkline Intellectual Property (No.2) Limited Pyridine dicarboxamide derivatives as bromodomain inhibitors
WO2018017938A1 (en) * 2016-07-22 2018-01-25 HCT Group Holdings Limited Pull down pump actuator
JP2019524792A (ja) 2016-08-08 2019-09-05 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited 化合物
GB201703282D0 (en) 2017-03-01 2017-04-12 Glaxosmithkline Intellectual Property (No 2) Ltd Compounds
GB201706102D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
US10414578B2 (en) * 2017-05-25 2019-09-17 Insys Development Company, Inc. Actuator for a package and method of use
GB201712081D0 (en) 2017-07-27 2017-09-13 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201716392D0 (en) 2017-10-06 2017-11-22 Glaxosmithkline Intellectual Property (No 2) Ltd Compounds
GB201716369D0 (en) 2017-10-06 2017-11-22 Glaxosmithkline Intellectual Property (No 2) Ltd Compounds
SG11202006453SA (en) 2018-01-17 2020-08-28 Glaxosmithkline Ip Dev Ltd Pi4kiiibeta inhibitors
CA3083040A1 (en) 2018-01-20 2019-07-25 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine compounds and methods of use
CN111867943B (zh) * 2018-03-22 2022-03-29 花王株式会社 包装容器和流体排出器
FR3082442B1 (fr) * 2018-06-13 2021-04-09 Aptar France Sas Dispositif de distribution de produit fluide
GB201814167D0 (en) 2018-08-31 2018-10-17 Glaxosmithkline Ip No 2 Ltd Compounds
FR3088224B1 (fr) 2018-11-14 2023-01-13 Aptar France Sas Dispositif de distribution de produit fluide.
US20220152319A1 (en) 2019-03-27 2022-05-19 ZETEO Biomedial, LLC Hand operated devices for administration of a medicament
EP3996784A1 (en) * 2019-07-12 2022-05-18 Sanofi Fluid dispensing device
FR3099070B1 (fr) * 2019-07-26 2021-11-12 Aptar France Sas Dispositif d'actionnement latéral pour distributeur de produit fluide
CN110329624B (zh) * 2019-08-14 2024-03-08 金东敏 定量挤压的胶水瓶
DE102019123737A1 (de) * 2019-09-04 2021-03-04 Henke-Sass, Wolf Gmbh Vorrichtung zum Applizieren eines Fluids
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
EP4166174B1 (de) * 2021-10-15 2025-02-12 Aptar Radolfzell GmbH Flüssigkeitsspender

Family Cites Families (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB173123A (en) 1920-10-22 1921-12-29 Alice Levy Improvements in atomizers
GB325629A (en) 1928-12-13 1930-02-27 Arthur Clarence Forster Improvements in and connected with closures or seals for jars, bottles, and similar containers, and in jars, bottles, and similar containers
GB405477A (en) 1932-05-09 1934-02-08 Rca Corp Photographic recording of sound
GB416671A (en) 1933-03-17 1934-09-17 Rudolf Lessing Improvements in and relating to the purification of combustion gases and apparatus therefor
GB659132A (en) 1949-04-19 1951-10-17 Rotherham & Sons Ltd Squirting or spraying devices
US2602569A (en) 1949-06-03 1952-07-08 Richard W Ryan Wall receptacle and dispenser for gaseous material
US2673008A (en) 1950-07-26 1954-03-23 Richard W Ryan Dispenser
US2904223A (en) 1957-10-16 1959-09-15 Richard W Ryan Operating plug for fragrance dispenser
GB906837A (en) 1960-02-23 1962-09-26 Alan Sidney Lewis Owensmith Dispenser for an aerosol device
FR1355588A (fr) 1963-01-07 1964-06-19 Oreal Nouveau dispositif de fixation pour flacons et en particulier pour flacons contenantune solution aérosol
GB1097254A (en) 1964-07-15 1968-01-03 Neotechnic Eng Ltd Improvements in or relating to actuators for pressurised aerosol dispensing containers
US3272391A (en) * 1965-02-18 1966-09-13 Meshberg Philip Actuator for dispensing package
US3405843A (en) 1966-11-23 1968-10-15 Cornelius B. Watson Jr. Container-dispenser for collapsible tubes
US3516424A (en) 1968-08-06 1970-06-23 Martin A Eagle Hair-care device
AT343788B (de) * 1973-11-30 1978-06-12 Thomae Gmbh Dr K Hemmvorrichtung fur pumpdosierventile
US4083476A (en) 1973-11-30 1978-04-11 Boehringer Ingelheim Gmbh Snap device for manually actuated liquid-atomizing pumps
DE7623770U1 (de) 1975-08-01 1979-08-30 Unilever Nv Behaelter fuer einen Aerosolspender
AU498046B2 (en) 1976-03-16 1979-02-01 3C Chemical Laboratories Pty Ltd A wall mountable actuator foran aerosal can
US4132359A (en) 1976-04-09 1979-01-02 Yoshino Kogyosho Co., Ltd. Manually operative atomizer
GB1531308A (en) 1976-11-22 1978-11-08 Johnson & Son Inc S C Dispensing receptacle for aerosol container
US4155487A (en) 1977-09-09 1979-05-22 Blake William S Trigger sprayer
US4402430A (en) 1980-09-29 1983-09-06 Alfred F. Washburn Mechanism for dispensing chemicals from a pressurized container
US4771769A (en) 1982-12-20 1988-09-20 Schering Corporation Hand held metered spray dispenser
NZ212911A (en) 1984-07-31 1988-06-30 Glaxo Group Ltd Aerosol dispensing device; actuator lever acts when cover in open position
FR2570000A1 (fr) 1984-09-12 1986-03-14 Valve Precision Sarl Dispositif de diffusion en matiere plastique pour recipient sous pression
US4648393A (en) 1984-11-02 1987-03-10 Ackrad Laboratories, Inc. Breath activated medication spray
DE8526339U1 (de) 1985-09-14 1987-05-07 Ing. Erich Pfeiffer GmbH & Co KG, 7760 Radolfzell Austragvorrichtung für fließfähige Medien
US4765515A (en) 1986-04-28 1988-08-23 Jerome Lippman Liquid dispensing combination
FR2606750B2 (fr) * 1986-07-07 1989-03-03 Oreal Recipient comprenant un col et une capsule manoeuvrable avec une seule main
US4944429A (en) 1987-08-28 1990-07-31 Schering Corporation Manually-operable spray dispenser with locking mechanism
DE3734306A1 (de) 1987-10-10 1989-04-27 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer fliessfaehige medien
DE3915397A1 (de) 1989-05-11 1990-11-15 Fraunhofer Ges Forschung Airless-spruehgeraet
JP2922935B2 (ja) * 1989-08-11 1999-07-26 東興薬品工業株式会社 粘稠液用鼻孔内噴霧容器の使捨てアダプタ
US5062549A (en) 1989-11-03 1991-11-05 Dowbrands Inc. Hand held, dip-tube style liquid dispenser
JPH0457264A (ja) 1990-06-22 1992-02-25 Sony Corp テープカセット
JPH0639808Y2 (ja) 1990-09-19 1994-10-19 小池化学株式会社 噴霧具
GB2251898A (en) 1990-11-29 1992-07-22 D M W Metered dose spray system
FR2671294A1 (fr) * 1991-01-09 1992-07-10 Savona Jean Louis Boitier rechargeable pour support de bombe anti-agression a gaz paralysant colore pour marquage et identification de l'agresseur.
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5273189A (en) 1991-02-14 1993-12-28 Societe Technique De Pulverisation - Step Device for spraying or dispensing a fluid, the device including a member sliding in its admission duct
US5377869A (en) * 1992-08-27 1995-01-03 Weiss; Stephan Pump dispenser with movable bottle
AU5376294A (en) 1992-11-11 1994-06-08 Tee Enterprises Limited An atomiser
FR2700279B1 (fr) 1993-01-14 1995-03-17 Valois Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé.
DE4436051C2 (de) * 1994-10-10 1996-08-14 Boehringer Ingelheim Kg Vorrichtung zum Betätigen von Aerosolabgabegeräten
JPH0948455A (ja) 1995-08-09 1997-02-18 Masashi Yuasa バスソープ容器
JPH09225363A (ja) 1996-02-23 1997-09-02 Lion Corp 手動式トリガータイプディスペンサーおよびそのノズル
DE19610456B4 (de) 1996-03-16 2006-10-19 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
JP3985064B2 (ja) 1996-05-29 2007-10-03 株式会社吉野工業所 トリガー式液体噴出器のノズルヘッド
DE19622124A1 (de) * 1996-06-01 1997-12-04 Alfred Von Schuckmann Gerät zum Aufbringen von Flüssigkeiten
JP3172993B2 (ja) 1996-06-15 2001-06-04 花王株式会社 ポンプ容器
JPH10179739A (ja) 1996-10-31 1998-07-07 Taisei Kako Kk 液体吐出容器
FR2758479B1 (fr) 1997-01-20 1999-03-26 Valois Dispositif pour distribuer un produit fluide ou pulverulent a une distance predeterminee
FR2761281B1 (fr) 1997-03-26 1999-05-21 Valois Sa Dispositif de pulverisation de produit fluide, tel q'un bidose
SE9701750D0 (sv) 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
IS4516A (is) * 1997-07-01 1999-01-02 Gizurarson Sveinbjörn Nýtt lyfjaform
DE19753147A1 (de) 1997-11-29 1999-06-02 Pfeiffer Erich Gmbh & Co Kg Spender mit manuell betätigbarer Ausbringeinrichtung
DE19756442A1 (de) 1997-12-18 1999-06-24 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
TR200002005T2 (tr) 1998-01-30 2000-11-21 Ig Spr�Htechnik Gmbh. Toz halindeki tıbbi uygulamada kullanılan ilaçların inhalasyonu için cihaz.
SE9801077D0 (sv) * 1998-03-27 1998-03-27 Shl Medical Ab Inhalator
GB9806937D0 (en) 1998-03-31 1998-05-27 Procter & Gamble A spray device
IE980530A1 (en) 1998-06-30 2000-02-09 Loctite R & D Ltd Device for Expressing Substances from a Deformable Tube
DE19831525A1 (de) 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
FR2781772B1 (fr) 1998-07-31 2000-10-13 Sofab Distributeur de produits liquides destines a etre delivres par pulverisation
GB9820938D0 (en) * 1998-09-26 1998-11-18 Glaxo Group Ltd Inhalation device
US6152330A (en) 1999-02-11 2000-11-28 Chester Labs, Inc. Hinged dispenser housing
GB0121568D0 (en) 2001-09-06 2001-10-24 Optinose As Nasal delivery device
JP2000355382A (ja) 1999-06-10 2000-12-26 Fujio Kutsuna スプレー缶入り殺虫剤
DE19944209A1 (de) 1999-09-15 2001-03-22 Pfeiffer Erich Gmbh & Co Kg Spender zum ggf. zerstäubten Ausbringen eines insbesondere flüssigen Mediums aus einem Behältnis
US6237812B1 (en) 1999-10-12 2001-05-29 Eiko-Sha Co. Ltd. Aerosol dispensing system
US6382204B1 (en) 1999-10-14 2002-05-07 Becton Dickinson And Company Drug delivery system including holder and drug container
US6382205B1 (en) 1999-11-02 2002-05-07 Robert E. Weinstein Method and device for organizing and coordinating the combined use of topical agents for the treatment of respiratory disorders
US6959708B1 (en) 1999-11-08 2005-11-01 Capnia, Incorporated Method for co-application of gases and drugs to potentiate their action in relieving headaches, angina and other ailments
US6302101B1 (en) 1999-12-14 2001-10-16 Daniel Py System and method for application of medicament into the nasal passage
US6644305B2 (en) 2000-04-14 2003-11-11 Trudell Medical International Nasal inhaler
FR2807954B1 (fr) 2000-04-20 2003-09-26 Cmc Jean Louis Vermeil Vaporisateur a actionnement lateral
DE10032976A1 (de) * 2000-07-06 2002-01-17 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
FR2812826B1 (fr) * 2000-08-11 2003-04-18 Valois Sa Dispositif de pulverisation a actionnement lateral, en particulier poussoir nasal
FR2813592B1 (fr) 2000-09-07 2003-03-21 Valois Sa Dispositif de distribution de produit fluide du type monodose ou bidose
FR2813593B1 (fr) 2000-09-07 2002-12-06 Valois Sa Dispositif de distribution de produit fluide de type multidose
US6338422B1 (en) 2000-10-11 2002-01-15 Saint-Gobain Calmar Inc. Actuation device for manually operated pump sprayer
DE10050982A1 (de) 2000-10-16 2002-04-18 Pfeiffer Erich Gmbh & Co Kg Spender und Verfahren zum Austragen von Medien
FR2817245B1 (fr) 2000-11-30 2003-05-02 Valois Sa Dispositif de distribution de produit fluide
SE0004751D0 (sv) 2000-12-19 2000-12-19 Astrazeneca Ab A delivery device
FR2818963B1 (fr) 2001-01-04 2003-04-11 Valois Sa Dispositif de distribution de produit fluide du type combidose
DE10110742A1 (de) 2001-02-28 2002-09-05 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
DE10121448A1 (de) 2001-05-02 2002-11-07 Alpla Werke Mit einem Flaschenbehältnis zusammenwirkende Verschlusskappe
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
US20020170923A1 (en) 2001-05-17 2002-11-21 Isaak Vatman Apparatus for dispensing paste material from a collapsible tube
WO2003011475A1 (en) 2001-07-31 2003-02-13 Canyon Co., Ltd. Pump dispenser and spray comprising it
DE10146815B4 (de) 2001-09-18 2005-05-04 Ing. Erich Pfeiffer Gmbh Spender für Medien
CA2460651C (en) 2001-09-21 2011-06-07 Ing. Erich Pfeiffer Gmbh Dosing device with a pumping device
US7182226B2 (en) 2001-09-21 2007-02-27 Ing. Erich Pfeiffer Gmbh Dosing device comprising a medium reservoir and corresponding pump device
CA2461006C (en) 2001-09-21 2007-07-31 Ing. Erich Pfeiffer Gmbh Dosing device with a medium reservoir and a pump device
FR2830522B1 (fr) * 2001-10-04 2004-02-13 Tebro Dispositif de distribution de produit fluide a actionnement lateral
FR2830519B1 (fr) 2001-10-04 2004-08-27 Valois Sa Dispositif de distribution de produit fluide a actionnement lateral
FR2832079B1 (fr) 2001-11-14 2004-07-30 Valois Sa Tete de distribution et distributeur de produit fluide comportant une telle tete de distribution
FR2832329B1 (fr) 2001-11-20 2004-11-19 Valois Sa Dispositif de pulverisation a actionnement lateral
DE10159692A1 (de) 2001-11-29 2003-06-12 Pfeiffer Erich Gmbh & Co Kg Dosiervorrichtung
FR2834920B1 (fr) 2002-01-22 2004-04-09 Valois Sa Dispositif de pulverisation a actionnement lateral
NZ535873A (en) * 2002-05-09 2006-07-28 Glaxo Group Ltd A fluid dispensing device
GB0217798D0 (en) 2002-08-01 2002-09-11 Glaxo Group Ltd A fluid dispensing device
GB0210605D0 (en) 2002-05-09 2002-06-19 Glaxo Group Ltd A fluid dispensing device
GB0217802D0 (en) 2002-08-01 2002-09-11 Glaxo Group Ltd A fluid dispensing device
US7635070B2 (en) 2002-08-06 2009-12-22 Ben Z. Cohen Dropper bottle and accessories therefor
GB0305583D0 (en) 2003-03-11 2003-04-16 Glaxo Group Ltd A fluid dispensing device
GB0322284D0 (en) 2003-09-23 2003-10-22 Glaxo Group Ltd Medicament dispenser
JP4196803B2 (ja) 2003-10-10 2008-12-17 日産自動車株式会社 内燃機関のシリンダブロック
PL1699512T3 (pl) 2003-11-03 2012-11-30 Glaxo Group Ltd Urządzenie do dozowania płynów
GB0405477D0 (en) 2004-03-11 2004-04-21 Glaxo Group Ltd A fluid dispensing device
GB0402695D0 (en) 2004-02-06 2004-03-10 Glaxo Group Ltd A metering pump system
GB0507224D0 (en) * 2005-04-09 2005-05-18 Glaxo Group Ltd A fluid dispensing device
JP5224209B2 (ja) * 2007-03-02 2013-07-03 孝仁 今川 二次元共鳴振動モーター

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011109883A1 (en) * 2010-03-08 2011-09-15 Victor Esteve Medicine dispensing device
GB2491326A (en) * 2010-03-08 2012-11-28 Victor Esteve Medicine dispensing device
DE202012007318U1 (de) 2011-10-27 2012-08-29 Victor Esteve Medikamentenabgabevorr.chtung
WO2013059889A1 (en) 2011-10-27 2013-05-02 Victor Esteve Medicine dispensing device
US9486592B2 (en) 2011-10-27 2016-11-08 Victor Esteve Medicine dispensing device

Also Published As

Publication number Publication date
US9320862B2 (en) 2016-04-26
BRPI0416128B8 (pt) 2021-06-22
CY1113086T1 (el) 2016-04-13
US20070131717A1 (en) 2007-06-14
WO2005044354A1 (en) 2005-05-19
JP2007510448A (ja) 2007-04-26
HK1094543A1 (en) 2007-04-04
US8752543B2 (en) 2014-06-17
CN102028994A (zh) 2011-04-27
CA2544378A1 (en) 2005-05-19
ES2388434T3 (es) 2012-10-15
AU2004287261A1 (en) 2005-05-19
DK1699512T3 (da) 2012-09-17
AU2004287261C1 (en) 2011-01-27
CN102028994B (zh) 2013-04-24
PT1699512E (pt) 2012-09-11
US20140290652A1 (en) 2014-10-02
CN1901958A (zh) 2007-01-24
AU2004287261B8 (en) 2011-01-27
AU2010246483A1 (en) 2010-12-23
JP4641526B2 (ja) 2011-03-02
BRPI0416128B1 (pt) 2018-08-07
PL1699512T3 (pl) 2012-11-30
EP1699512B1 (en) 2012-06-20
EP1699512A1 (en) 2006-09-13
CN1901958B (zh) 2011-03-09
AU2010246483B2 (en) 2013-05-02
AU2004287261B2 (en) 2010-08-26

Similar Documents

Publication Publication Date Title
BRPI0416128A (pt) dispositivo de dispensação de fluido, e, kit de partes
BR0309373A (pt) Dispositivo de dispensão de fluido, montagem de alojamento, e, conjunto de partes
BR0208404A (pt) Válvula
BRPI0413251A (pt) sistema de perfuração e método para perfurar um furo de sondagem em uma formação geológica
BRPI0413532A (pt) dispositivo de infusão tipo remendo
BRPI0818296B8 (pt) sistema de geração de aerossol e método de produzir aerossol
BRPI0414341A (pt) sistema de válvulas em estágios absorvedor de choque
BR9803640A (pt) Aparelho e processo para operar uma válvula de isolamento de formação posicionada em perfuração de poço
BR0308770A (pt) Cabeçote distribuidor montado em uma haste atuadora oca móvel
BR0312230A (pt) Dispositivos dispensador de fluido para pulverizar um fluido para dentro de uma cavidade de corpo, e de descarga de fluido, e, montagem de alojamento para os mesmos
BRPI0505491A (pt) conjunto para pré-carregar uma camisa de cilindro, método para pré-carregar uma camisa de cilindro, e, conjunto de cartucho de camisa de cilindro para inserção em um corpo de cilindro
BR112017015483A2 (pt) conjunto, coluna de ferramenta e método
BRPI0408812A (pt) distribuidor de produto fluido
BR0315909A (pt) Bomba dispensadora de lìquido viscoso
BR112015030744A2 (pt) dispositivo de controle para o comando de freios de uma combinação de veículo de tração e trailer
BRPI0410578A (pt) dispositivo de alìvio de pressão para uma bomba
BRPI0513182A (pt) unidade e dispositivo para dispensar fluidos, e, sistema para dispensar um fluido ou uma mistura
BR0004056A (pt) Válvula de bocal
AR074331A1 (es) Dispositivo dispensador de medicacion
BRPI0412610A (pt) Recipiente de fluido de impressão
BRPI0409245A (pt) dispositivo para acoplamento de um suprimento de refrigerante em um cilindro
BR0312328A (pt) Conjunto distribuidor de fluido
BRPI0417925A (pt) membro distribuidor de fluido
BR0308044A (pt) Distribuidor de fluido
BR0214127A (pt) Válvula, e, conjunto válvula

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/11/2004, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B25G Requested change of headquarter approved

Owner name: GLAXO GROUP LIMITED (GB)

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 21A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2854 DE 16-09-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.