BRPI0416589A - métodos para a produção de apolipoproteìnas em plantas transgências - Google Patents
métodos para a produção de apolipoproteìnas em plantas transgênciasInfo
- Publication number
- BRPI0416589A BRPI0416589A BRPI0416589-6A BRPI0416589A BRPI0416589A BR PI0416589 A BRPI0416589 A BR PI0416589A BR PI0416589 A BRPI0416589 A BR PI0416589A BR PI0416589 A BRPI0416589 A BR PI0416589A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- apolipoprotein
- methods
- apolipoproteins
- production
- Prior art date
Links
- 102000007592 Apolipoproteins Human genes 0.000 title abstract 6
- 108010071619 Apolipoproteins Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Botany (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"MéTODOS PARA A PRODUçãO DE APOLIPOPROTEìNAS EM PLANTAS TRANSGêNCIAS". Métodos para a produção de uma apolipoproteína em plantas são descritos. Em uma forma de realização, a presente invenção provê um método para a expressão de apolipoproteína em plantas compreendendo: (a) prover uma construção de ácido nucleico quimérico compreendendo na direção 5<39> a 3<39> de transcrição, como componentes ligados de modo operativo: (i) uma seqüência de ácido nucleico capaz de controlar a expressão em células de plantas; e (ii) uma seqüência de ácido nucleico codificando um polipeptídeo de apolipoproteína; (b) introduzir a construção de ácido nucleico quimérico em uma célula de planta; e cultivar a célula de planta em uma planta madura capaz de produzir sementes em que a semente expressa apolipoproteína.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51960603P | 2003-11-14 | 2003-11-14 | |
| US57973304P | 2004-06-16 | 2004-06-16 | |
| PCT/CA2004/001960 WO2005047455A2 (en) | 2003-11-14 | 2004-11-15 | Methods for the production of apolipoproteins in transgenic plants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0416589A true BRPI0416589A (pt) | 2007-01-30 |
Family
ID=34594972
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416589-6A BRPI0416589A (pt) | 2003-11-14 | 2004-11-15 | métodos para a produção de apolipoproteìnas em plantas transgências |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7786352B2 (pt) |
| EP (1) | EP1682664A4 (pt) |
| JP (1) | JP2007510420A (pt) |
| KR (1) | KR20060124633A (pt) |
| CN (1) | CN1906296B (pt) |
| AR (1) | AR047769A1 (pt) |
| AU (1) | AU2004289720B2 (pt) |
| BR (1) | BRPI0416589A (pt) |
| CA (1) | CA2544239A1 (pt) |
| EA (1) | EA015167B1 (pt) |
| IL (1) | IL175248A0 (pt) |
| MX (1) | MXPA06005363A (pt) |
| NO (1) | NO20062480L (pt) |
| NZ (1) | NZ547024A (pt) |
| TW (1) | TW200526778A (pt) |
| WO (1) | WO2005047455A2 (pt) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2833076C1 (ru) * | 2024-05-28 | 2025-01-14 | Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук | Способ выращивания обогащенного антоцианами листового салата |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ526822A (en) * | 2000-12-19 | 2005-03-24 | Sembiosys Genetics Inc | Methods for the production of multimeric proteins for producing an oil body associated with a recombinant protein complex preferably thioredoxin or an immunoglobin, in transgenic plants and their use in compositons for reducing allergenicity of food |
| WO2012047930A2 (en) * | 2010-10-04 | 2012-04-12 | The Regents Of The University Of California | Compositions and methods for treatment of gynecologic cancers |
| BRPI0613726A2 (pt) | 2005-07-01 | 2011-02-01 | Cornell Res Foundation Inc | molécula de ácido nucléico de café (coffea spp), molécula de mrna e cdna, oligonucleotìdeo, vetor, método para modular o sabor ou aroma de grãos de café, promotor, gene quimérico |
| US9637753B2 (en) * | 2006-08-10 | 2017-05-02 | Plantechno S.R.L. | In-plant production of oligomeric (comprising three or more units) forms of human Apo A-1 protein muteins |
| WO2008028121A1 (en) | 2006-08-31 | 2008-03-06 | Monsanto Technology Llc | Plant transformation without selection |
| JP2009201435A (ja) * | 2008-02-28 | 2009-09-10 | Toyota Motor Corp | 種子中の油脂量の評価方法及び油脂含量が変化した植物体のスクリーニング方法 |
| EP2298883B1 (en) * | 2008-05-28 | 2016-07-27 | Kyoto University | Novel selection marker gene and use thereof |
| US9714937B2 (en) | 2009-10-13 | 2017-07-25 | Nanostring Technologies, Inc. | Protein detection via nanoreporters |
| CN102127562B (zh) * | 2009-12-09 | 2013-01-30 | 安胜军 | 一种种子特异型表达载体及其构建方法与应用 |
| EP2468871A1 (en) * | 2010-12-23 | 2012-06-27 | Philip Morris Products S.A. | Method for producing apolipoprotein in plants |
| KR20210095240A (ko) | 2011-07-12 | 2021-07-30 | 임파서블 푸즈 인크. | 소비재를 위한 방법 및 조성물 |
| US10039306B2 (en) | 2012-03-16 | 2018-08-07 | Impossible Foods Inc. | Methods and compositions for consumables |
| US20140220217A1 (en) | 2011-07-12 | 2014-08-07 | Maraxi, Inc. | Method and compositions for consumables |
| BR112014000681B1 (pt) | 2011-07-12 | 2020-03-10 | Maraxi, Inc. | Réplica de queijo contendo proteínas de origem vegetal e gorduras derivadas de nozes, leguminosas ou sementes, bactéria, fungo ou alga |
| US9539300B2 (en) | 2012-03-31 | 2017-01-10 | The Regents Of The University Of California | Modulating disease through genetic engineering of plants |
| PL2943072T3 (pl) | 2013-01-11 | 2018-05-30 | Impossible Foods Inc. | Sposoby i kompozycje do wpływania na profil smakowy i zapachowy artykułów konsumpcyjnych |
| AU2014205122B2 (en) | 2013-01-11 | 2017-11-02 | Impossible Foods Inc. | Non-dairy cheese replica comprising a coacervate |
| CN106455626A (zh) | 2014-03-31 | 2017-02-22 | 非凡食品有限公司 | 碎肉仿品 |
| RU2016144908A (ru) | 2014-05-02 | 2018-06-05 | Серени Терапеутикс Холдинг Са | Маркеры hdl-терапии |
| JP2017537904A (ja) * | 2014-11-21 | 2017-12-21 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 合成ペプチド |
| US20160208274A1 (en) * | 2015-01-21 | 2016-07-21 | Northeastern State University | Blood clot-dissolving proteins produced in seeds |
| EP3088414A1 (de) * | 2015-04-30 | 2016-11-02 | Euroimmun Medizinische Labordiagnostika AG | Verbesserter nachweis von nussallergien |
| IT201600081193A1 (it) * | 2016-08-02 | 2018-02-02 | Grg Gene Tech Sa | COMPOSIZIONI PER SOMMINISTRAZIONE DI ApoA1 E DOSAGGI |
| US12454705B2 (en) | 2018-03-25 | 2025-10-28 | Emendobio Inc. | Differential knockout of an allele of a heterozygous apolipoprotein A1 (APO1A) gene |
| CN114470234A (zh) * | 2022-01-14 | 2022-05-13 | 川北医学院附属医院 | 一种负载阿托伐他汀的靶向纳米材料制备方法和应用 |
| CN114990134B (zh) * | 2022-05-30 | 2023-07-25 | 扬州大学 | 一种水稻油体蛋白基因OsOle6及其编码蛋白与应用 |
| CN115290776A (zh) * | 2022-07-26 | 2022-11-04 | 云南大学 | 瘤牛锥虫病抗性蛋白的应用 |
| CN119842804B (zh) * | 2023-10-17 | 2025-12-05 | 南京农业大学 | 大豆Caleosin编码基因GmCLO1的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3971856A (en) | 1975-03-03 | 1976-07-27 | Archer Daniels Midland Company | Process for preparing soy protein concentrate |
| US4956282A (en) | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
| NL8901932A (nl) | 1989-07-26 | 1991-02-18 | Mogen Int | Produktie van heterologe eiwitten in planten of plantecellen. |
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| US5202422A (en) | 1989-10-27 | 1993-04-13 | The Scripps Research Institute | Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use |
| US5650554A (en) | 1991-02-22 | 1997-07-22 | Sembiosys Genetics Inc. | Oil-body proteins as carriers of high-value peptides in plants |
| US6750046B2 (en) * | 1991-02-22 | 2004-06-15 | Sembiosys Genetics, Inc. | Preparation of thioredoxin and thioredoxin reductase proteins on oil bodies |
| US5948682A (en) | 1991-02-22 | 1999-09-07 | Sembiosys Genetics Inc. | Preparation of heterologous proteins on oil bodies |
| US6753167B2 (en) | 1991-02-22 | 2004-06-22 | Sembiosys Genetics Inc. | Preparation of heterologous proteins on oil bodies |
| US6288304B1 (en) | 1991-02-22 | 2001-09-11 | Sembiosys Genetics Inc. | Expression of somatotropin in plant seeds |
| SE9500778D0 (sv) | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
| GB9926084D0 (en) * | 1999-11-03 | 2000-01-12 | King S College London | Recombinant fusion molecules |
| WO2001042441A2 (en) * | 1999-12-08 | 2001-06-14 | International Centre For Genetic Engineering And Biotechnology | Plastid transformation |
| GB2364705A (en) * | 2000-07-14 | 2002-02-06 | Icgeb | Fusion protein expression in plastids |
| NZ526822A (en) * | 2000-12-19 | 2005-03-24 | Sembiosys Genetics Inc | Methods for the production of multimeric proteins for producing an oil body associated with a recombinant protein complex preferably thioredoxin or an immunoglobin, in transgenic plants and their use in compositons for reducing allergenicity of food |
| TWI345587B (en) * | 2003-06-17 | 2011-07-21 | Sembiosys Genetics Inc | Methods for the production of insulin in plants |
-
2004
- 2004-11-12 TW TW093134564A patent/TW200526778A/zh unknown
- 2004-11-15 MX MXPA06005363 patent/MXPA06005363A/es active IP Right Grant
- 2004-11-15 WO PCT/CA2004/001960 patent/WO2005047455A2/en not_active Ceased
- 2004-11-15 AR ARP040104214A patent/AR047769A1/es not_active Application Discontinuation
- 2004-11-15 EP EP04797212A patent/EP1682664A4/en not_active Withdrawn
- 2004-11-15 NZ NZ547024A patent/NZ547024A/en not_active IP Right Cessation
- 2004-11-15 BR BRPI0416589-6A patent/BRPI0416589A/pt not_active IP Right Cessation
- 2004-11-15 CA CA002544239A patent/CA2544239A1/en not_active Abandoned
- 2004-11-15 AU AU2004289720A patent/AU2004289720B2/en not_active Ceased
- 2004-11-15 EA EA200600946A patent/EA015167B1/ru not_active IP Right Cessation
- 2004-11-15 KR KR1020067011765A patent/KR20060124633A/ko not_active Ceased
- 2004-11-15 US US10/987,454 patent/US7786352B2/en not_active Expired - Fee Related
- 2004-11-15 CN CN2004800404508A patent/CN1906296B/zh not_active Expired - Fee Related
- 2004-11-15 JP JP2006538622A patent/JP2007510420A/ja active Pending
-
2006
- 2006-04-27 IL IL175248A patent/IL175248A0/en unknown
- 2006-05-30 NO NO20062480A patent/NO20062480L/no not_active Application Discontinuation
-
2010
- 2010-06-18 US US12/819,068 patent/US20120059150A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2833076C1 (ru) * | 2024-05-28 | 2025-01-14 | Федеральное государственное бюджетное научное учреждение Уфимский федеральный исследовательский центр Российской академии наук | Способ выращивания обогащенного антоцианами листового салата |
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06005363A (es) | 2006-07-19 |
| EA200600946A1 (ru) | 2006-12-29 |
| US7786352B2 (en) | 2010-08-31 |
| US20050172359A1 (en) | 2005-08-04 |
| CN1906296B (zh) | 2013-09-11 |
| US20120059150A1 (en) | 2012-03-08 |
| JP2007510420A (ja) | 2007-04-26 |
| IL175248A0 (en) | 2006-09-05 |
| AU2004289720B2 (en) | 2011-02-03 |
| TW200526778A (en) | 2005-08-16 |
| WO2005047455A2 (en) | 2005-05-26 |
| WO2005047455A3 (en) | 2005-07-21 |
| EP1682664A2 (en) | 2006-07-26 |
| CN1906296A (zh) | 2007-01-31 |
| AU2004289720A1 (en) | 2005-05-26 |
| EA015167B1 (ru) | 2011-06-30 |
| NO20062480L (no) | 2006-08-09 |
| EP1682664A4 (en) | 2008-04-02 |
| AR047769A1 (es) | 2006-02-22 |
| KR20060124633A (ko) | 2006-12-05 |
| CA2544239A1 (en) | 2005-05-26 |
| NZ547024A (en) | 2009-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: SEMBIOSYS GENETICS INC. (CA) , MAURICE M. MOLONEY |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |