BRPI0411479A - métodos para a produção de insulina em plantas - Google Patents

métodos para a produção de insulina em plantas

Info

Publication number
BRPI0411479A
BRPI0411479A BRPI0411479-5A BRPI0411479A BRPI0411479A BR PI0411479 A BRPI0411479 A BR PI0411479A BR PI0411479 A BRPI0411479 A BR PI0411479A BR PI0411479 A BRPI0411479 A BR PI0411479A
Authority
BR
Brazil
Prior art keywords
insulin
plants
methods
seed
nucleic acid
Prior art date
Application number
BRPI0411479-5A
Other languages
English (en)
Inventor
Maurice M Moloney
Joseph Boothe
Richard Keon
Cory Nykiforuk
Gijs Van Rooijen
Original Assignee
Sembiosys Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sembiosys Genetics Inc filed Critical Sembiosys Genetics Inc
Publication of BRPI0411479A publication Critical patent/BRPI0411479A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"MéTODOS PARA A PRODUçãO DE INSULINA EM PLANTAS". Esta invenção refere-se a métodos para produzir insulina em plantas. Em uma modalidade, a presente invenção fornece um método para a expressão de insulina, compreendendo: (a) fornecer um constructo de ácidos nucléicos quimérico que compreende na direção de 5<39>para 3<39> da transcrição como componentes ligados operacionalmente: (i) uma seqüência de ácidos nucléicos capaz de controlar a expressão em células de sementes vegetais; e (ii) uma seqüência de ácidos nucléicos que codifica um polipeptídeo de insulina; (b) introduzir a construção de ácidos nucléicos em uma célula vegetal; e (c) desenvolver a semente vegetal para dar uma planta madura capaz de formar semente, onde a semente expressa insulina.
BRPI0411479-5A 2003-06-17 2004-06-17 métodos para a produção de insulina em plantas BRPI0411479A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47881803P 2003-06-17 2003-06-17
US54953904P 2004-03-04 2004-03-04
PCT/CA2004/000896 WO2004111244A2 (en) 2003-06-17 2004-06-17 Methods for the production of insulin in plants

Publications (1)

Publication Number Publication Date
BRPI0411479A true BRPI0411479A (pt) 2006-07-25

Family

ID=33555509

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411479-5A BRPI0411479A (pt) 2003-06-17 2004-06-17 métodos para a produção de insulina em plantas

Country Status (23)

Country Link
US (2) US7547821B2 (pt)
EP (2) EP1959017A1 (pt)
JP (2) JP4864701B2 (pt)
KR (1) KR101216762B1 (pt)
CN (1) CN1836047B (pt)
AR (1) AR044803A1 (pt)
AT (1) ATE405660T1 (pt)
AU (1) AU2004247762B2 (pt)
BR (1) BRPI0411479A (pt)
CA (1) CA2528741A1 (pt)
CY (1) CY1108477T1 (pt)
DE (1) DE602004015980D1 (pt)
DK (1) DK1633876T3 (pt)
EA (1) EA014887B1 (pt)
ES (1) ES2313018T3 (pt)
IL (1) IL172469A (pt)
MX (1) MXPA05013723A (pt)
NO (1) NO20055885L (pt)
NZ (1) NZ544522A (pt)
PL (1) PL1633876T3 (pt)
PT (1) PT1633876E (pt)
TW (1) TWI345587B (pt)
WO (1) WO2004111244A2 (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393998B2 (en) 2002-03-08 2008-07-01 Prodigene, Inc. Commercial production of insulin and insulin-like proteins in plants
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
AU2003280870A1 (en) * 2002-11-12 2004-06-03 Ckd Bio Corp. Plasmids expressing human insulin and the preparation method for human insuling thereby
US20040173547A1 (en) * 2003-03-06 2004-09-09 Roth Michael Carl Bolt on attachment to facilitate hanging of pneumatic tool
TWI345587B (en) * 2003-06-17 2011-07-21 Sembiosys Genetics Inc Methods for the production of insulin in plants
JP2007535896A (ja) * 2003-06-20 2007-12-13 セムバイオシス ジェネティクス インコーポレイテッド 修飾されたオレオシン
TW200526778A (en) * 2003-11-14 2005-08-16 Sembiosys Genetics Inc Methods for the production of apolipoproteins in transgenic plants
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
NZ563676A (en) 2005-05-23 2011-01-28 Arcadia Biosciences Inc Safflower with elevated gamma-linolenic acid
US20080274143A1 (en) * 2005-05-27 2008-11-06 Henry Daniell Chloroplasts Engineering to Express Pharmaceutical Proteins
BRPI0613726A2 (pt) 2005-07-01 2011-02-01 Cornell Res Foundation Inc molécula de ácido nucléico de café (coffea spp), molécula de mrna e cdna, oligonucleotìdeo, vetor, método para modular o sabor ou aroma de grãos de café, promotor, gene quimérico
US8343914B2 (en) * 2006-01-06 2013-01-01 Case Western Reserve University Fibrillation resistant proteins
WO2008028121A1 (en) 2006-08-31 2008-03-06 Monsanto Technology Llc Plant transformation without selection
EP2074140B8 (en) 2006-10-04 2015-10-28 Case Western Reserve University Fibrillation-resistant insulin and insulin analogues
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
WO2009129250A2 (en) * 2008-04-14 2009-10-22 Case Western Reserve University Meal-time insulin analogues of enhanced stability
AU2009240636A1 (en) * 2008-04-22 2009-10-29 Case Western Reserve University Isoform-specific insulin analogues
PL219335B1 (pl) * 2008-07-04 2015-04-30 Inst Biotechnologii I Antybiotyków Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna
KR20120129875A (ko) 2008-07-31 2012-11-28 케이스 웨스턴 리저브 유니버시티 염소화 아미노산을 갖는 인슐린 유사체
US9200053B2 (en) 2008-07-31 2015-12-01 Case Western Reserve University Insulin analogues containing penta-fluoro-Phenylalanine at position B24
CN101736029B (zh) * 2008-11-21 2013-01-02 复旦大学 一种利用植物油体蛋白表达系统生产人胰岛素样生长因子-i的方法
US8399407B2 (en) * 2009-09-17 2013-03-19 Case Western Reserve University Non-standard insulin analogues
RU2012123642A (ru) 2009-12-11 2014-01-20 Кейз Вестерн Ризев Юнивесити Аналоги инсулина, содержащие хлорированные аминокислоты
CN102268451B (zh) * 2010-06-01 2014-03-12 安胜军 一种含有人胰岛素基因的表达载体及其构建方法与应用
US20130097731A1 (en) 2010-06-16 2013-04-18 Futuragene Israel Ltd. Pest-resistant plants containing a combination of a spider toxin and a chitinase
US20130164288A1 (en) 2010-09-07 2013-06-27 Protalix Ltd. Readthrough acetylcholinesterase (ache-r) for treating or preventing parkinson's disease
WO2013059213A1 (en) * 2011-10-18 2013-04-25 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
US9352456B2 (en) 2011-10-26 2016-05-31 Black & Decker Inc. Power tool with force sensing electronic clutch
EP2836508B1 (en) 2012-04-11 2016-06-29 Novo Nordisk A/S Insulin formulations
US9163073B2 (en) 2013-04-17 2015-10-20 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
KR101625746B1 (ko) 2013-09-23 2016-05-31 순천대학교 산학협력단 프로미니인슐린 재조합 단백질이 발현된 형질전환 식물 및 이의 제조방법
AU2015328222B9 (en) 2014-10-06 2020-12-24 Case Western Reserve University Biphasic single-chain insulin analogues
US20220096607A1 (en) * 2015-04-09 2022-03-31 Kinetiq Therapeutics, Llc Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
KR102642178B1 (ko) * 2017-08-08 2024-02-29 중앙대학교 산학협력단 돌연변이에 의해, 혈중 반감기 및 공수병 바이러스 중화 효능이 증대된 공수병 바이러스 중화 항체
US20210032307A1 (en) * 2018-02-09 2021-02-04 Jiangsu Hengrui Medicine Co., Ltd. Codon optimized precursor gene and signal peptide gene of human insulin analogue
US20220144915A1 (en) * 2019-04-19 2022-05-12 The Trustees Of Indiana University Stabilization of prandial or basal insulin analogues by an internal diselenide bridge
FI4069278T3 (fi) * 2019-12-06 2025-07-16 Dr Mary Morris & Ass Llc Menetelmiä ja koostumuksia tyypin 1 diabeteksen ehkäisemiseksi
IL299545A (en) * 2020-07-03 2023-02-01 Kriya Therapeutics Inc Different insulin and glucokinase nucleic acids for the treatment of diabetes
EP4190905A1 (en) 2021-12-01 2023-06-07 Core Biogenesis Method for the purification of recombinant proteins using oil body proteins
WO2026076425A1 (en) 2024-10-04 2026-04-09 Biodrive, Inc. Oral biodelivery platform

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3971856A (en) 1975-03-03 1976-07-27 Archer Daniels Midland Company Process for preparing soy protein concentrate
US6174724B1 (en) 1983-01-17 2001-01-16 Monsanto Company Chimeric genes suitable for expression in plant cells
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
DK58285D0 (da) 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US5008241A (en) 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
US4956282A (en) 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
CA1313830C (en) 1985-08-07 1993-02-23 Dilip Maganlal Shah Glyphosate-resistant plants
US5273894A (en) 1986-08-23 1993-12-28 Hoechst Aktiengesellschaft Phosphinothricin-resistance gene, and its use
US5268463A (en) 1986-11-11 1993-12-07 Jefferson Richard A Plant promoter α-glucuronidase gene construct
EP0292435B1 (en) 1987-05-20 1995-07-26 Ciba-Geigy Ag Zea mays plants and transgenic zea mays plants regenerated from protoplasts or protoplast-derived cells
DK336188D0 (da) 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
CA1341467C (en) 1988-07-29 2004-12-07 John C. Rogers Producing commercially valuable polypeptides with genetically transformed endosperm tissue
HUT56857A (en) 1988-12-23 1991-10-28 Novo Nordisk As Human insulin analogues
ES2199931T3 (es) 1989-03-24 2004-03-01 Syngenta Participations Ag Plantas transgenicas resistentes a enfermedades.
NL8901932A (nl) 1989-07-26 1991-02-18 Mogen Int Produktie van heterologe eiwitten in planten of plantecellen.
US4940935A (en) 1989-08-28 1990-07-10 Ried Ashman Manufacturing Automatic SMD tester
US5202422A (en) 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
KR910014790A (ko) 1990-01-10 1991-08-31 한태희 랩탑 컴퓨터의 기능선택방법 및 인터페이스회로
WO1991013993A1 (en) * 1990-03-05 1991-09-19 The Upjohn Company Protein expression via seed specific regulatory sequences
US5650554A (en) 1991-02-22 1997-07-22 Sembiosys Genetics Inc. Oil-body proteins as carriers of high-value peptides in plants
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
ES2187505T3 (es) 1992-04-02 2003-06-16 Sembiosys Genetics Inc Elementos cis de proteinas de cuerpo oleoso como señales reguladoras.
DE69332803T2 (de) * 1992-12-28 2004-03-04 Stichting Scheikundig Onderzoek In Nederland (Son) Verfahren zur herstellung transgener pflanzen mit modifiziertem fructanmuster
US5474978A (en) 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5461031A (en) 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
US5633437A (en) 1994-10-11 1997-05-27 Sandoz Ltd. Gene exhibiting resistance to acetolactate synthase inhibitor herbicides
US6040496A (en) 1995-06-30 2000-03-21 Novartis Finance Corporation Use of translationally altered RNA to confer resistance to maize dwarf mosaic virus and other monocotyledonous plant viruses
US5577474A (en) * 1995-11-29 1996-11-26 General Motors Corporation Torque estimation for engine speed control
WO1997029200A1 (de) * 1996-02-08 1997-08-14 Institut für Pflanzengenetik und Kulturpflanzenforschung Kassetten zur expression von lagerstabilen proteinen in pflanzen
US5856452A (en) * 1996-12-16 1999-01-05 Sembiosys Genetics Inc. Oil bodies and associated proteins as affinity matrices
MX219629B (es) 1997-04-25 2004-03-30 Sembiosys Genetics Inc Metodo para separar proteinas de fusion
DE69836552T3 (de) * 1997-09-30 2014-10-09 The Regents Of The University Of California Herstellung von proteinen in pflanzensamen
WO1999055890A1 (en) 1998-04-27 1999-11-04 Demegen, Inc. A method for increasing the protein content of plants
US6429357B1 (en) 1999-05-14 2002-08-06 Dekalb Genetics Corp. Rice actin 2 promoter and intron and methods for use thereof
MX248919B (es) 1999-08-27 2007-09-11 Sembiosys Genetics Inc Promotores especificos de semilla de lino.
US6521738B2 (en) 1999-12-29 2003-02-18 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogs
EP1274846A4 (en) * 2000-03-01 2004-09-29 Univ Auburn PLASTIDE TRANSFORMATION VECTOR FOR THE EXPRESSION OF HUMAN PROTEINS IN PLANTS
CN1295129A (zh) * 2000-08-25 2001-05-16 林忠平 利用转基因番茄生产人胰岛素的方法
NZ526822A (en) * 2000-12-19 2005-03-24 Sembiosys Genetics Inc Methods for the production of multimeric proteins for producing an oil body associated with a recombinant protein complex preferably thioredoxin or an immunoglobin, in transgenic plants and their use in compositons for reducing allergenicity of food
EP1261119A3 (en) 2001-05-22 2003-11-12 Powerdsine Limited Power factor corrector with efficient ripple attenuator
US7393998B2 (en) * 2002-03-08 2008-07-01 Prodigene, Inc. Commercial production of insulin and insulin-like proteins in plants
CN1382734A (zh) * 2002-03-15 2002-12-04 林忠平 利用转基因生菜生产人胰岛素的方法
TWI345587B (en) * 2003-06-17 2011-07-21 Sembiosys Genetics Inc Methods for the production of insulin in plants

Also Published As

Publication number Publication date
AU2004247762A1 (en) 2004-12-23
ATE405660T1 (de) 2008-09-15
US20090282583A1 (en) 2009-11-12
JP2007523611A (ja) 2007-08-23
DK1633876T3 (da) 2008-12-08
US7547821B2 (en) 2009-06-16
CN1836047A (zh) 2006-09-20
PT1633876E (pt) 2008-11-03
ES2313018T3 (es) 2009-03-01
CY1108477T1 (el) 2014-04-09
CA2528741A1 (en) 2004-12-23
IL172469A (en) 2011-08-31
HK1088037A1 (en) 2006-10-27
EA014887B1 (ru) 2011-02-28
KR101216762B1 (ko) 2013-01-02
CN1836047B (zh) 2010-12-22
JP4864701B2 (ja) 2012-02-01
TW200510529A (en) 2005-03-16
MXPA05013723A (es) 2006-03-13
PL1633876T3 (pl) 2009-01-30
IL172469A0 (en) 2006-04-10
DE602004015980D1 (de) 2008-10-02
US20050039235A1 (en) 2005-02-17
EP1633876A2 (en) 2006-03-15
WO2004111244A2 (en) 2004-12-23
EP1959017A1 (en) 2008-08-20
JP2011200251A (ja) 2011-10-13
EA200600050A1 (ru) 2006-06-30
EP1633876B1 (en) 2008-08-20
AU2004247762B2 (en) 2010-05-27
AR044803A1 (es) 2005-10-05
TWI345587B (en) 2011-07-21
NO20055885L (no) 2006-01-17
KR20060052705A (ko) 2006-05-19
WO2004111244A3 (en) 2005-02-03
NZ544522A (en) 2008-03-28

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