BRPI0417220A - processo de purificação de beta interferon humano - Google Patents

processo de purificação de beta interferon humano

Info

Publication number: BRPI0417220A
Authority: BR; Brazil
Prior art keywords: beta interferon; human beta; interferon; purification process; affinity chromatography
Prior art date: 2003-12-04

Application number

BRPI0417220-5A

Other languages

English (en)

Portuguese (pt)

Inventor

Ji Sook Park

Jong Sang Chung

Min Ji Baek

Jee Won Ahn

Ki Wan Kim

Hyung Ki Park

Dong Eok Lee

Myung Suk Oh

Original Assignee

Cj Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-04

Filing date

2004-12-04

Publication date

2007-02-21

2004-12-04 Application filed by Cj Corp filed Critical Cj Corp

2007-02-21 Publication of BRPI0417220A publication Critical patent/BRPI0417220A/pt

Links

101001033280 Homo sapiens Cytokine receptor common subunit beta Proteins 0.000 title abstract 4
102000014150 Interferons Human genes 0.000 title abstract 4
108010050904 Interferons Proteins 0.000 title abstract 4
102000055647 human CSF2RB Human genes 0.000 title abstract 4
229940079322 interferon Drugs 0.000 title abstract 4
238000000746 purification Methods 0.000 title abstract 2
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 6
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
238000001042 affinity chromatography Methods 0.000 abstract 3
102000003996 Interferon-beta Human genes 0.000 abstract 2
108090000467 Interferon-beta Proteins 0.000 abstract 2
239000007853 buffer solution Substances 0.000 abstract 2
239000011780 sodium chloride Substances 0.000 abstract 2
239000011534 wash buffer Substances 0.000 abstract 2
238000000034 method Methods 0.000 abstract 1
QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 abstract 1
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
238000004366 reverse phase liquid chromatography Methods 0.000 abstract 1
238000004007 reversed phase HPLC Methods 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BRPI0417220-5A 2003-12-04 2004-12-04 processo de purificação de beta interferon humano BRPI0417220A (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR10-2003-0087552A KR100524871B1 (ko)	2003-12-04	2003-12-04	인터페론 베타의 정제방법
PCT/KR2004/003179 WO2005054288A1 (en)	2003-12-04	2004-12-04	Process for purifying interferon beta

Publications (1)

Publication Number	Publication Date
BRPI0417220A true BRPI0417220A (pt)	2007-02-21

Family

ID=36647277

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0417220-5A BRPI0417220A (pt)	2003-12-04	2004-12-04	processo de purificação de beta interferon humano

Country Status (14)

Country	Link
US (1)	US7780960B2 (de)
EP (1)	EP1697411B1 (de)
JP (1)	JP2007530447A (de)
KR (1)	KR100524871B1 (de)
CN (1)	CN100462370C (de)
AT (1)	ATE521712T1 (de)
AU (1)	AU2004295265B2 (de)
BR (1)	BRPI0417220A (de)
CA (1)	CA2548160C (de)
ES (1)	ES2369911T3 (de)
MX (1)	MXPA06006357A (de)
PL (1)	PL1697411T3 (de)
RU (1)	RU2346003C2 (de)
WO (1)	WO2005054288A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007022799A1 (en) *	2005-08-26	2007-03-01	Ares Trading S.A.	Process for the preparation of glycosylated interferon beta
KR100848600B1 (ko) *	2007-02-28	2008-07-28	인하대학교 산학협력단	완충용액을 이용한 재조합 단백질 대량생산 방법
RU2392282C1 (ru) *	2008-10-06	2010-06-20	Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН	СПОСОБ ОЧИСТКИ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА β-1b
CN114573679B (zh) *	2022-03-29	2024-10-11	深圳科兴药业有限公司	分离重组人干扰素α1b异构体的纯化方法
CN114814000B (zh) *	2022-03-30	2024-07-23	深圳科兴药业有限公司	重组人干扰素的含量检测方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5564799A (en)	1978-11-07	1980-05-15	Toray Ind Inc	Multi-stage concentration and purification of interferon originated from human fibroblast
US4289689A (en) *	1980-03-14	1981-09-15	Hoffmann-La Roche Inc.	Preparation of homogeneous human fibroblast interferon
US4278661A (en)	1979-10-12	1981-07-14	E. I. Du Pont De Nemours And Company	Purification of interferon
NL7907791A (nl)	1979-10-23	1981-04-27	Stichting Rega V Z W	Werkwijze voor het zuiveren van interferon.
JPS58201794A (ja)	1982-05-17	1983-11-24	Toray Ind Inc	ヒトインターフェロンβの濃縮精製法
US4966843A (en)	1982-11-01	1990-10-30	Cetus Corporation	Expression of interferon genes in Chinese hamster ovary cells
US4483849A (en) *	1983-01-07	1984-11-20	Carter William A	Stabilization and purification of interferon with propylene glycol, resulting in a non-toxic product
US4658017A (en)	1984-02-14	1987-04-14	Health Research, Inc. (Roswell Park Division)	Method for the large scale purification of human fibroblast interferon
US4808523A (en) *	1984-11-07	1989-02-28	Yeda Research And Development Co., Ltd.	Constitutive production of human IFN-β1 by mammalian cells transformed by the IFN-β1 gene fused to an SV40 early promoter
FR2617763B1 (fr)	1987-07-07	1989-12-01	Essilor Int	Procede de fabrication de lentille de contact en un polymere proteique naturel, par moulage avant reticulation
IT1222427B (it)	1987-07-31	1990-09-05	Sclavo Spa	Procedimento per la purificazione di interferone
DE4128319A1 (de) *	1991-08-27	1993-03-04	Bioferon Biochem Substanz	Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
EP0551535A1 (de) *	1992-01-13	1993-07-21	SCLAVO S.p.A.	Verfahren zur Reinigung von rekombinant-menschlichem Interferon-Beta, dadurch gereinigtes Interferon-Beta und pharmazeutische Zusammensetzungen, die diese enthalten
US7144574B2 (en)	1999-08-27	2006-12-05	Maxygen Aps	Interferon β variants and conjugates

2003
- 2003-12-04 KR KR10-2003-0087552A patent/KR100524871B1/ko not_active Expired - Fee Related
2004
- 2004-12-04 ES ES04808310T patent/ES2369911T3/es not_active Expired - Lifetime
- 2004-12-04 AT AT04808310T patent/ATE521712T1/de not_active IP Right Cessation
- 2004-12-04 EP EP04808310A patent/EP1697411B1/de not_active Expired - Lifetime
- 2004-12-04 CN CNB2004800397241A patent/CN100462370C/zh not_active Expired - Fee Related
- 2004-12-04 BR BRPI0417220-5A patent/BRPI0417220A/pt not_active IP Right Cessation
- 2004-12-04 US US10/581,602 patent/US7780960B2/en not_active Expired - Fee Related
- 2004-12-04 MX MXPA06006357A patent/MXPA06006357A/es active IP Right Grant
- 2004-12-04 CA CA2548160A patent/CA2548160C/en not_active Expired - Fee Related
- 2004-12-04 WO PCT/KR2004/003179 patent/WO2005054288A1/en not_active Ceased
- 2004-12-04 AU AU2004295265A patent/AU2004295265B2/en not_active Ceased
- 2004-12-04 PL PL04808310T patent/PL1697411T3/pl unknown
- 2004-12-04 RU RU2006123539/13A patent/RU2346003C2/ru not_active IP Right Cessation
- 2004-12-04 JP JP2006542505A patent/JP2007530447A/ja active Pending

Also Published As

Publication number	Publication date
AU2004295265A1 (en)	2005-06-16
EP1697411A1 (de)	2006-09-06
KR100524871B1 (ko)	2005-10-31
CN1902225A (zh)	2007-01-24
US20070093649A1 (en)	2007-04-26
MXPA06006357A (es)	2006-08-23
CN100462370C (zh)	2009-02-18
EP1697411B1 (de)	2011-08-24
ES2369911T3 (es)	2011-12-09
JP2007530447A (ja)	2007-11-01
EP1697411A4 (de)	2008-08-27
AU2004295265B2 (en)	2009-01-08
ATE521712T1 (de)	2011-09-15
RU2346003C2 (ru)	2009-02-10
KR20050054209A (ko)	2005-06-10
CA2548160C (en)	2011-06-07
PL1697411T3 (pl)	2011-12-30
US7780960B2 (en)	2010-08-24
WO2005054288A1 (en)	2005-06-16
CA2548160A1 (en)	2005-06-16
RU2006123539A (ru)	2008-01-10

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Legal Events

Date	Code	Title	Description
2009-09-29	B25A	Requested transfer of rights approved	Owner name: CJ CHEILJEDANG CORPORATION (KR) Free format text: TRANSFERIDO DE: CJ CORPORATION
2012-04-03	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2015-03-17	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 11A ANUIDADE.
2016-03-29	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.