BRPI0507988A - compostos e composições imunossupressores - Google Patents
compostos e composições imunossupressoresInfo
- Publication number
- BRPI0507988A BRPI0507988A BRPI0507988-8A BRPI0507988A BRPI0507988A BR PI0507988 A BRPI0507988 A BR PI0507988A BR PI0507988 A BRPI0507988 A BR PI0507988A BR PI0507988 A BRPI0507988 A BR PI0507988A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- immunosuppressive compounds
- compounds
- immunosuppressive
- diseases
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 230000001506 immunosuppresive effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 102000036530 EDG receptors Human genes 0.000 abstract 1
- 108091007263 EDG receptors Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
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- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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Abstract
COMPOSTOS E COMPOSIçõES IMUNOSSUPRESSORES . A presente invenção refere-se a imunossupressor, a processo para sua produção, a seus usos e a composições farmacêuticas contendo eles. A invenção provê uma nova classe de compostos úteis no tratamento ou na prevenção de doenças ou distúrbios mediados por interações de linfócito, particularmente doenças associadas à tradução de sinal mediada de receptor de EDG.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54775704P | 2004-02-24 | 2004-02-24 | |
| PCT/US2005/006311 WO2005082089A2 (en) | 2004-02-24 | 2005-02-24 | Immunosuppressant compounds and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0507988A true BRPI0507988A (pt) | 2007-07-31 |
Family
ID=34910935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0507988-8A BRPI0507988A (pt) | 2004-02-24 | 2005-02-24 | compostos e composições imunossupressores |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7572811B2 (pt) |
| EP (1) | EP1718307A4 (pt) |
| JP (1) | JP4891095B2 (pt) |
| CN (1) | CN1921863B (pt) |
| AR (1) | AR047976A1 (pt) |
| AU (1) | AU2005216540B2 (pt) |
| BR (1) | BRPI0507988A (pt) |
| CA (1) | CA2554627A1 (pt) |
| MX (1) | MXPA06009622A (pt) |
| PE (1) | PE20060283A1 (pt) |
| TW (1) | TW200538433A (pt) |
| WO (1) | WO2005082089A2 (pt) |
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| AU2005292984B2 (en) | 2004-10-12 | 2011-01-20 | Kyorin Pharmaceutical Co., Ltd. | Process for producing 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol hydrochloride or hydrate thereof and intermediate for the same |
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| JP2020507610A (ja) | 2017-02-16 | 2020-03-12 | アリーナ ファーマシューティカルズ, インコーポレイテッド | 腸管外症状を伴う炎症性腸疾患の治療のための化合物および方法 |
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| WO2019032632A1 (en) | 2017-08-09 | 2019-02-14 | Bristol-Myers Squibb Company | ALKYLPHENYL COMPOUNDS |
| US11059784B2 (en) | 2017-08-09 | 2021-07-13 | Bristol-Myers Squibb Company | Oxime ether compounds |
| AU2019280822A1 (en) | 2018-06-06 | 2021-01-07 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| EP3847158A1 (en) | 2018-09-06 | 2021-07-14 | Arena Pharmaceuticals, Inc. | Compounds useful in the treatment of autoimmune and inflammatory disorders |
| CN113072474A (zh) * | 2018-12-06 | 2021-07-06 | 上海济煜医药科技有限公司 | 作为免疫调节剂的化合物及其制备方法和应用 |
| AU2020417293A1 (en) | 2020-01-03 | 2022-09-01 | Berg Llc | Polycyclic amides as UBE2K modulators for treating cancer |
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| IL86632A0 (en) | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
| US5633250A (en) * | 1991-12-18 | 1997-05-27 | Schering Corporation | Imidazoylalkyl substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms |
| DE19911510A1 (de) * | 1999-03-15 | 2000-09-21 | Boehringer Ingelheim Pharma | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| ATE441654T1 (de) * | 2002-01-18 | 2009-09-15 | Merck & Co Inc | Edg-rezeptoragonisten |
| JP2005533058A (ja) * | 2002-06-17 | 2005-11-04 | メルク エンド カムパニー インコーポレーテッド | Edg受容体アゴニストとしての1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)アゼチジン−3−カルボキシラートおよび1−((5−アリール−1,2,4−オキサジアゾール−3−イル)ベンジル)ピロリジン−3−カルボキシラート |
| AU2004251146A1 (en) | 2003-05-19 | 2005-01-06 | Irm, Llc | Immunosuppressant compounds and compositions |
| WO2004113330A1 (en) * | 2003-05-19 | 2004-12-29 | Irm Llc | Immunosuppressant compounds and compositions |
| CN1787817B (zh) | 2003-05-19 | 2011-09-07 | Irm责任有限公司 | 免疫抑制剂化合物及组合物 |
| MY150088A (en) * | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
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2005
- 2005-02-23 TW TW094105492A patent/TW200538433A/zh unknown
- 2005-02-24 BR BRPI0507988-8A patent/BRPI0507988A/pt not_active IP Right Cessation
- 2005-02-24 JP JP2006554340A patent/JP4891095B2/ja not_active Expired - Fee Related
- 2005-02-24 WO PCT/US2005/006311 patent/WO2005082089A2/en not_active Ceased
- 2005-02-24 AR ARP050100680A patent/AR047976A1/es unknown
- 2005-02-24 CA CA002554627A patent/CA2554627A1/en not_active Abandoned
- 2005-02-24 CN CN2005800059894A patent/CN1921863B/zh not_active Expired - Fee Related
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- 2005-02-24 US US10/590,618 patent/US7572811B2/en not_active Expired - Fee Related
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- 2005-02-24 EP EP05723960A patent/EP1718307A4/en not_active Withdrawn
- 2005-02-24 AU AU2005216540A patent/AU2005216540B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1718307A2 (en) | 2006-11-08 |
| WO2005082089A3 (en) | 2006-05-04 |
| AR047976A1 (es) | 2006-03-15 |
| PE20060283A1 (es) | 2006-05-06 |
| CA2554627A1 (en) | 2005-09-09 |
| JP4891095B2 (ja) | 2012-03-07 |
| AU2005216540B2 (en) | 2008-06-26 |
| AU2005216540A1 (en) | 2005-09-09 |
| CN1921863B (zh) | 2013-04-03 |
| WO2005082089A2 (en) | 2005-09-09 |
| EP1718307A4 (en) | 2009-04-29 |
| JP2007523910A (ja) | 2007-08-23 |
| CN1921863A (zh) | 2007-02-28 |
| US7572811B2 (en) | 2009-08-11 |
| MXPA06009622A (es) | 2007-03-26 |
| US20070203100A1 (en) | 2007-08-30 |
| TW200538433A (en) | 2005-12-01 |
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