BRPI0508485A - compostos de pentafluorsulfanila, sua fabricação e uso como agentes farmacêuticos - Google Patents

compostos de pentafluorsulfanila, sua fabricação e uso como agentes farmacêuticos

Info

Publication number
BRPI0508485A
BRPI0508485A BRPI0508485-7A BRPI0508485A BRPI0508485A BR PI0508485 A BRPI0508485 A BR PI0508485A BR PI0508485 A BRPI0508485 A BR PI0508485A BR PI0508485 A BRPI0508485 A BR PI0508485A
Authority
BR
Brazil
Prior art keywords
compounds
manufacture
pharmaceutical agents
pentafluorsulfanyl
above compounds
Prior art date
Application number
BRPI0508485-7A
Other languages
English (en)
Inventor
Birgit Bossenmaier
Walter-Gunar Friebe
Guy Georges
Matthias Rueth
Edgar Voss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0508485A publication Critical patent/BRPI0508485A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPOSTOS DE PENTAFLUORSULFANILA, SUA FABRICAçãO E USO COMO AGENTES FARMACêUTICOS. Os objetivos da presente invenção são os compostos de fórmula I-A(I),, seus sais famaceuticamente aceitáveis, formas enantioméricas, diastereoisómeros e racematos, a preparação dos composto acima mencionados, medicamentos contendo os mesmos e sua fabricação, bem como o uso dos compostos acima mencionados no controle ou prevenção de doenças tais como câncer.
BRPI0508485-7A 2004-03-05 2005-03-04 compostos de pentafluorsulfanila, sua fabricação e uso como agentes farmacêuticos BRPI0508485A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04005275 2004-03-05
PCT/EP2005/002310 WO2005095388A1 (en) 2004-03-05 2005-03-04 Pentafluorosulfanyl compounds, their manufacture and use as pharmaceutical agents

Publications (1)

Publication Number Publication Date
BRPI0508485A true BRPI0508485A (pt) 2007-07-31

Family

ID=34895965

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0508485-7A BRPI0508485A (pt) 2004-03-05 2005-03-04 compostos de pentafluorsulfanila, sua fabricação e uso como agentes farmacêuticos

Country Status (12)

Country Link
US (1) US7235574B2 (pt)
EP (1) EP1725549A1 (pt)
JP (1) JP2007526275A (pt)
KR (1) KR20060124746A (pt)
CN (1) CN1930153A (pt)
AR (1) AR047922A1 (pt)
AU (1) AU2005229352A1 (pt)
BR (1) BRPI0508485A (pt)
CA (1) CA2557402A1 (pt)
RU (1) RU2006135084A (pt)
TW (1) TW200531688A (pt)
WO (1) WO2005095388A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7317124B2 (en) 2003-11-13 2008-01-08 Sanofi-Aventis Deutschland Gmbh Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates
TW200533657A (en) 2004-02-17 2005-10-16 Esteve Labor Dr Substituted pyrazoline compounds, their preparation and use as medicaments
TW200612914A (en) * 2004-03-05 2006-05-01 Hoffmann La Roche Novel oxidized thioether derivatives, their manufacture and use as pharmaceutical agents
TW200533346A (en) * 2004-03-18 2005-10-16 Hoffmann La Roche Novel ether derivatives, their manufacture and use as pharmaceutical agents
AR050652A1 (es) * 2004-09-24 2006-11-08 Hoffmann La Roche Derivados de oxazol, preparacion y uso como inhibidores de la tirosina quinasa
WO2008101212A2 (en) * 2007-02-16 2008-08-21 State University Of New York At Albany Pentafluorosulfanyl containing amino acids
WO2009028514A1 (ja) * 2007-08-28 2009-03-05 Ube Industries, Ltd. ペンタフルオロスルファニルベンゼン化合物の製造方法、及び新規なペンタフルオロスルファニルベンゼン化合物
CN101981034B (zh) * 2008-02-05 2013-08-14 赛诺菲-安万特 作为par1抑制剂的三唑并哒嗪、其制备及其制备药物的用途
SI2242740T1 (sl) * 2008-02-05 2013-03-29 Sanofi SF5-derivati kot PAR1 inhibitorji, njihova priprava in uporaba kot zdravila
BRPI0907487A2 (pt) * 2008-02-05 2015-07-14 Sanofi Aventis Sais de triazólio como inibidores de par1, produção dos mesmos e uso como medicamentos
WO2012094451A1 (en) * 2011-01-06 2012-07-12 Beta Pharma Canada Inc. Novel ureas for the treatment and prevention of cancer
CN104557646B (zh) 2011-02-15 2017-08-29 宇部兴产株式会社 生产芳基硫五氟化物的工业方法
US9682931B2 (en) * 2013-11-01 2017-06-20 Ube Industries, Ltd. Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof
CN112920133B (zh) * 2021-01-29 2022-09-16 中国医科大学 (e)-4-甲基-2-(4-(三氟甲基)苯乙烯基)噁唑类化合物及其制备方法与用途
CN120097880B (zh) * 2025-05-09 2025-07-25 内蒙古大学 一种烯丙基五氟硫基化合物及其制备方法和应用
CN121850978A (zh) * 2026-03-16 2026-04-14 苏州大学 一种五氟硫基硫鎓盐固体试剂及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2260999C (en) 1996-07-19 2006-07-11 Takeda Chemical Industries, Ltd. Heterocyclic compounds, their production and use in tyrosine kinase inhibition
PE20011178A1 (es) 2000-04-07 2001-11-19 Takeda Chemical Industries Ltd Compuestos heterociclicos y su produccion
EP1439178A4 (en) * 2001-10-05 2005-11-16 Takeda Pharmaceutical Heterocyclic compounds, oxazole derivatives, process for their preparation and their use
JP2003277379A (ja) * 2002-01-17 2003-10-02 Takeda Chem Ind Ltd 含窒素複素環化合物、その製造法および用途
JP2004059452A (ja) * 2002-07-25 2004-02-26 Asahi Glass Co Ltd ペンタフルオロサルファー置換ベンズイミダゾール化合物およびその製造方法
US7596415B2 (en) * 2002-12-06 2009-09-29 Medtronic, Inc. Medical devices incorporating carbon nanotube material and methods of fabricating same
US7259262B2 (en) * 2003-10-24 2007-08-21 Hoffmann-La Roche Inc. Arylazole derivatives, their manufacture and use as pharmaceutical agents
TW200612914A (en) * 2004-03-05 2006-05-01 Hoffmann La Roche Novel oxidized thioether derivatives, their manufacture and use as pharmaceutical agents
US7288557B2 (en) * 2004-09-21 2007-10-30 Hoffmann-La Roche Inc. Triazole derivatives
AR050652A1 (es) * 2004-09-24 2006-11-08 Hoffmann La Roche Derivados de oxazol, preparacion y uso como inhibidores de la tirosina quinasa
US20060116407A1 (en) * 2004-11-22 2006-06-01 Birgit Bossenmaier Amide derivatives

Also Published As

Publication number Publication date
US20050197370A1 (en) 2005-09-08
CA2557402A1 (en) 2005-10-13
CN1930153A (zh) 2007-03-14
EP1725549A1 (en) 2006-11-29
KR20060124746A (ko) 2006-12-05
TW200531688A (en) 2005-10-01
WO2005095388A1 (en) 2005-10-13
AU2005229352A1 (en) 2005-10-13
AR047922A1 (es) 2006-03-01
JP2007526275A (ja) 2007-09-13
US7235574B2 (en) 2007-06-26
RU2006135084A (ru) 2008-04-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A E 6A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE A 8.6 NA RPI 2099 DE 29/03/2011.