BRPI0509901A - aparelho e método para liberação transdérmica de agentes com base em fentanila - Google Patents

aparelho e método para liberação transdérmica de agentes com base em fentanila

Info

Publication number
BRPI0509901A
BRPI0509901A BRPI0509901-3A BRPI0509901A BRPI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A
Authority
BR
Brazil
Prior art keywords
fentanyl
microprojection member
based agent
based agents
contained
Prior art date
Application number
BRPI0509901-3A
Other languages
English (en)
Inventor
Mahmoud Ameri
Michel J N Cormier
Yuh-Fun Maa
Peter Daddona
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0509901A publication Critical patent/BRPI0509901A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

APARELHO E MéTODO PARA LIBERAçãO TRANSDéRMICA DE AGENTES COM BASE EM FENTANILA. A presente invenção refere-se a um aparelho e método para transdermicamente liberar um agente biologicamente ativo compreendendo um sistema de liberação tendo um membro de microprojeção (ou sistema) que inclui uma pluralidade de microprojeções (ou conjunto destas) que são adaptadas para perfurar através do stratum corneum na camada da epiderme subjacente, ou camadas da epiderme e da derme. Em uma modalidade, o agente com base em fentanila está contido em um revestimento biocompatível que é aplicado ao membro de microprojeção. Em uma outra modalidade, o sistema de liberação inclui um pacote de gel tendo uma formulação de hidrogel contendo agente com base em fentanila que é disposta no membro de microprojeção após aplicação à pele de um paciente. Em uma modalidade alternativa, o agente com base em fentanila está contido tanto no revestimento quanto na formulação de hidrogel.
BRPI0509901-3A 2004-04-13 2005-03-18 aparelho e método para liberação transdérmica de agentes com base em fentanila BRPI0509901A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56194904P 2004-04-13 2004-04-13
PCT/US2005/009153 WO2005102334A2 (en) 2004-04-13 2005-03-18 Apparatus and method for transdermal delivery of fentany-based agents

Publications (1)

Publication Number Publication Date
BRPI0509901A true BRPI0509901A (pt) 2007-08-07

Family

ID=35197490

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509901-3A BRPI0509901A (pt) 2004-04-13 2005-03-18 aparelho e método para liberação transdérmica de agentes com base em fentanila

Country Status (12)

Country Link
US (1) US20050226922A1 (pt)
EP (1) EP1737434A2 (pt)
JP (1) JP2007532645A (pt)
KR (1) KR20070011469A (pt)
CN (1) CN101027045A (pt)
AR (1) AR048827A1 (pt)
AU (1) AU2005235075A1 (pt)
BR (1) BRPI0509901A (pt)
CA (1) CA2562731A1 (pt)
MX (1) MXPA06011972A (pt)
TW (1) TW200602099A (pt)
WO (1) WO2005102334A2 (pt)

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AU2012202731B2 (en) * 2005-06-17 2014-06-19 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
CN101198362B (zh) 2005-06-17 2014-03-12 威斯康星校友研究基金会 在癌症化疗和放疗时保护细胞的局部血管收缩剂制品和方法
AU2014202738B2 (en) * 2005-06-17 2016-05-12 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
WO2007068045A1 (en) * 2005-12-14 2007-06-21 Ariana Holdings Pty Ltd Chemical applicator
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
HUP0700828A2 (en) * 2007-12-20 2010-01-28 Richter Gedeon Nyrt Transdermal pharmaceutical compositions containing tolperisone alone and in combination
CA2734333A1 (en) * 2008-09-16 2010-03-25 Nektar Therapeutics Pegylated opioids with low potential for abuse
US8439896B2 (en) * 2009-11-13 2013-05-14 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8888761B2 (en) 2009-11-13 2014-11-18 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8894630B2 (en) 2009-11-13 2014-11-25 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
WO2011096468A1 (ja) 2010-02-05 2011-08-11 株式会社ニチレイバイオサイエンス 免疫組織化学染色用前処理液及びその濃縮液
CN105815785A (zh) * 2016-03-31 2016-08-03 常州大学 一种从黄瓜中提取丙醇二酸制备除脂粉的方法
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
IL269957B (en) 2017-04-18 2022-08-01 Breakthrough Tech Llc Sulfur production
JP7837672B2 (ja) * 2017-12-14 2026-03-31 エルテーエス ローマン テラピー－ジステーメ アーゲー 塩形態の有効成分を含むマイクロニードルアレイ
CN108318646A (zh) * 2018-03-27 2018-07-24 苏州桓晨医疗科技有限公司 一种模拟药物体外释放的释放介质
JP2023522699A (ja) * 2020-04-22 2023-05-31 エマージェクス ユーエスエー コーポレーション コロナウイルスワクチンでコーティングされた微小突起を有する経皮活性剤送達デバイス

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Also Published As

Publication number Publication date
WO2005102334A2 (en) 2005-11-03
CN101027045A (zh) 2007-08-29
EP1737434A2 (en) 2007-01-03
TW200602099A (en) 2006-01-16
KR20070011469A (ko) 2007-01-24
MXPA06011972A (es) 2007-04-16
AR048827A1 (es) 2006-05-31
JP2007532645A (ja) 2007-11-15
AU2005235075A1 (en) 2005-11-03
WO2005102334A3 (en) 2006-02-09
CA2562731A1 (en) 2005-11-03
US20050226922A1 (en) 2005-10-13

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]