BRPI0415967A - aplicação de conjugados de polìmero de peptìdeos e proteìnas terapêuticos através de microprojeções revestidas - Google Patents

aplicação de conjugados de polìmero de peptìdeos e proteìnas terapêuticos através de microprojeções revestidas

Info

Publication number
BRPI0415967A
BRPI0415967A BRPI0415967-5A BRPI0415967A BRPI0415967A BR PI0415967 A BRPI0415967 A BR PI0415967A BR PI0415967 A BRPI0415967 A BR PI0415967A BR PI0415967 A BRPI0415967 A BR PI0415967A
Authority
BR
Brazil
Prior art keywords
application
therapeutic proteins
polymer conjugates
peptide polymer
microprojections
Prior art date
Application number
BRPI0415967-5A
Other languages
English (en)
Inventor
Samuel Zalipsky
Johanna H Bentz
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0415967A publication Critical patent/BRPI0415967A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00893—Material properties pharmaceutically effective
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

"APLICAçãO DE CONJUGADOS DE POLìMERO DE PEPTìDEOS E PROTEìNAS TERAPêUTICOS ATRAVéS DE MICROPROJEçõES REVESTIDAS". A presente invenção refere-se a um aparelho para aplicar transdermalmente um agente biologicamente ativo a um paciente compreendendo um membro de microprojeção tendo uma pluralidade de microprojeções que são adaptadas para perfurar o estrato córneo do paciente, o membro da microprojeção tendo um revestimento biocompatível disposto sobre ele que inclui um agente biologicamente ativo selecionado do grupo consistindo em conjugados de peptídeo e proteína.
BRPI0415967-5A 2003-10-28 2004-10-21 aplicação de conjugados de polìmero de peptìdeos e proteìnas terapêuticos através de microprojeções revestidas BRPI0415967A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51539803P 2003-10-28 2003-10-28
PCT/US2004/034925 WO2005044985A2 (en) 2003-10-28 2004-10-21 Delivery of polymer conjugates of therapeutic peptides and proteins via coated microporjections

Publications (1)

Publication Number Publication Date
BRPI0415967A true BRPI0415967A (pt) 2007-01-23

Family

ID=34572834

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0415967-5A BRPI0415967A (pt) 2003-10-28 2004-10-21 aplicação de conjugados de polìmero de peptìdeos e proteìnas terapêuticos através de microprojeções revestidas

Country Status (11)

Country Link
US (1) US20050106227A1 (pt)
EP (1) EP1677687A4 (pt)
JP (1) JP2007535337A (pt)
KR (1) KR20070001886A (pt)
CN (1) CN1897883A (pt)
AR (1) AR047229A1 (pt)
AU (1) AU2004287059A1 (pt)
BR (1) BRPI0415967A (pt)
CA (1) CA2543280A1 (pt)
TW (1) TW200539907A (pt)
WO (1) WO2005044985A2 (pt)

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US20050090009A1 (en) * 2003-10-23 2005-04-28 Cormier Michel J. Compositions of stabilized DNA for coating microprojctions
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KR101724655B1 (ko) * 2014-06-02 2017-04-13 주식회사 아모라이프사이언스 마이크로 니들 패치 및 그의 제조 방법
KR102676629B1 (ko) 2015-04-29 2024-06-18 래디어스 파마슈티컬스, 인코포레이티드 암을 치료하는 방법
CN105833424A (zh) * 2016-03-21 2016-08-10 南通纺织丝绸产业技术研究院 一种丝素蛋白微针贴及其制备方法
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Also Published As

Publication number Publication date
TW200539907A (en) 2005-12-16
US20050106227A1 (en) 2005-05-19
EP1677687A4 (en) 2008-09-17
CN1897883A (zh) 2007-01-17
AR047229A1 (es) 2006-01-11
WO2005044985A2 (en) 2005-05-19
AU2004287059A1 (en) 2005-05-19
CA2543280A1 (en) 2005-05-19
KR20070001886A (ko) 2007-01-04
JP2007535337A (ja) 2007-12-06
WO2005044985A3 (en) 2005-10-20
EP1677687A2 (en) 2006-07-12

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012.