BRPI0510840A - composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide - Google Patents
composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróideInfo
- Publication number
- BRPI0510840A BRPI0510840A BRPI0510840-3A BRPI0510840A BRPI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A
- Authority
- BR
- Brazil
- Prior art keywords
- corticosteroid
- vitamin
- composition
- pharmaceutical composition
- pressurized
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000003246 corticosteroid Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 229930003316 Vitamin D Natural products 0.000 title abstract 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
- 239000000443 aerosol Substances 0.000 title abstract 2
- 235000019166 vitamin D Nutrition 0.000 title abstract 2
- 239000011710 vitamin D Substances 0.000 title abstract 2
- 150000003710 vitamin D derivatives Chemical class 0.000 title abstract 2
- 229940046008 vitamin d Drugs 0.000 title abstract 2
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 238000005187 foaming Methods 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSIçãO FARMACêUTICA, COMPOSIçãO PRESSURIZADA, BOMBA AEROSSOL E USO DE UMA MISTURA DE ANáLOGO DE VITAMINA D E DE UM CORTICOSTERóIDE A presente invenção tem por objeto uma composição farmacêutica espumante de uso tópico, estável, destinada ao tratamento da psoríase, que compreende uma fase hidrófila, pelo menos uma fase hidrófoba, um agente tensoativo, e a título de princípio ativo uma associação de análogo de vitamina D e de corticosteróide e pelo menos um gás propulsor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0406613A FR2871696B1 (fr) | 2004-06-17 | 2004-06-17 | Composition topique pour le traitement du psoriasis |
| PCT/FR2005/001496 WO2006005844A1 (fr) | 2004-06-17 | 2005-06-15 | Composition moussante pressurisee pour le traitement topique du psoriasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0510840A true BRPI0510840A (pt) | 2007-11-27 |
Family
ID=34949090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0510840-3A BRPI0510840A (pt) | 2004-06-17 | 2005-06-15 | composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20050281755A1 (pt) |
| EP (1) | EP1778185A1 (pt) |
| JP (1) | JP2008502663A (pt) |
| KR (1) | KR20070024598A (pt) |
| CN (1) | CN1968681A (pt) |
| AU (1) | AU2005261571A1 (pt) |
| BR (1) | BRPI0510840A (pt) |
| CA (1) | CA2567687A1 (pt) |
| FR (1) | FR2871696B1 (pt) |
| MX (1) | MXPA06014409A (pt) |
| RU (1) | RU2007101540A (pt) |
| WO (1) | WO2006005844A1 (pt) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263580B2 (en) * | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| AUPP583198A0 (en) * | 1998-09-11 | 1998-10-01 | Soltec Research Pty Ltd | Mousse composition |
| US8512718B2 (en) | 2000-07-03 | 2013-08-20 | Foamix Ltd. | Pharmaceutical composition for topical application |
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US8119150B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Non-flammable insecticide composition and uses thereof |
| US8900554B2 (en) | 2002-10-25 | 2014-12-02 | Foamix Pharmaceuticals Ltd. | Foamable composition and uses thereof |
| ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| US20060018937A1 (en) * | 2002-10-25 | 2006-01-26 | Foamix Ltd. | Steroid kit and foamable composition and uses thereof |
| US8486376B2 (en) | 2002-10-25 | 2013-07-16 | Foamix Ltd. | Moisturizing foam containing lanolin |
| US7820145B2 (en) | 2003-08-04 | 2010-10-26 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US8119109B2 (en) | 2002-10-25 | 2012-02-21 | Foamix Ltd. | Foamable compositions, kits and methods for hyperhidrosis |
| US7575739B2 (en) | 2003-04-28 | 2009-08-18 | Foamix Ltd. | Foamable iodine composition |
| US8795693B2 (en) | 2003-08-04 | 2014-08-05 | Foamix Ltd. | Compositions with modulating agents |
| US8486374B2 (en) | 2003-08-04 | 2013-07-16 | Foamix Ltd. | Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses |
| US8211449B2 (en) * | 2004-06-24 | 2012-07-03 | Dpt Laboratories, Ltd. | Pharmaceutically elegant, topical anhydrous aerosol foam |
| WO2007039825A2 (en) | 2005-05-09 | 2007-04-12 | Foamix Ltd. | Saccharide foamable compositions |
| EP2526930B1 (en) * | 2005-06-01 | 2013-12-25 | GlaxoSmithKline Intellectual Property Development Limited | Vitamin formulation |
| US20080064669A1 (en) * | 2006-08-29 | 2008-03-13 | Rakefet Cohen | Stable pharmacologically active compositions including vitamin D-containing and corticosteroid compounds with low pH compatibility |
| GB2443161B (en) * | 2006-10-28 | 2011-03-23 | Nupharm Lab Ltd | Clobetasol spray |
| GB2443162B (en) * | 2006-10-28 | 2011-02-09 | Nupharm Lab Ltd | Betamethasone spray |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US9532936B2 (en) * | 2007-03-08 | 2017-01-03 | Strength Of Nature, Llc | Compositions and methods for removing hair styling aids |
| EP1970048A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D |
| EP1970049A1 (en) * | 2007-03-15 | 2008-09-17 | Drug Delivery Solutions Limited | Polyaphron topical composition with vitamin D and corticosteroid |
| US10265265B2 (en) * | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
| FR2915097B1 (fr) * | 2007-04-18 | 2012-09-28 | Fabre Pierre Dermo Cosmetique | Mousse antifongique a base de ciclopiroxolamine et de pyrithione de zinc et ses applications medicales et cosmetiques. |
| EP2008651A1 (en) | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| US8518376B2 (en) | 2007-12-07 | 2013-08-27 | Foamix Ltd. | Oil-based foamable carriers and formulations |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| EP2242476A2 (en) | 2008-01-14 | 2010-10-27 | Foamix Ltd. | Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses |
| EP2343978A4 (en) * | 2008-10-03 | 2013-11-27 | Nexmed Holdings Inc | STABILIZED COMPOSITION FOR TREATING PSORIASIS |
| US20120238535A1 (en) * | 2009-02-23 | 2012-09-20 | Smith Jan G | Topical formulation of low level clobetasol propionate for treating disorders of the skin and mucous membranes |
| PT2400951T (pt) * | 2009-02-25 | 2018-11-26 | Mayne Pharma Llc | Composições de espuma tópica |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
| KR101749514B1 (ko) | 2010-06-11 | 2017-06-21 | 레오 파마 에이/에스 | 비타민 d 유사체 및 코르티코스테로이드를 포함하는 약제학적 분무 조성물 |
| AU2015203836B2 (en) * | 2010-06-11 | 2016-09-01 | Leo Pharma A/S | A pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid |
| HRP20191711T1 (hr) | 2011-03-14 | 2019-12-13 | Drug Delivery Solutions Ltd | Oftalmološki pripravak |
| EP2951164B1 (en) | 2013-01-29 | 2019-06-05 | Avexxin AS | Antiinflammatory and antitumor 2-oxothiazoles compounds |
| JP6396229B2 (ja) * | 2014-01-27 | 2018-09-26 | 株式会社ポーラファルマ | 使用時泡状を呈する外用医薬組成物 |
| JP6396230B2 (ja) * | 2014-01-27 | 2018-09-26 | 株式会社ポーラファルマ | 使用時泡状を呈する外用医薬組成物 |
| GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
| FR3041538B1 (fr) * | 2015-09-29 | 2018-11-30 | Galderma Research & Development | Mousse chimique non rincee contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis. |
| GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
| GB201604316D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| CN109789111B (zh) | 2016-09-21 | 2021-11-16 | 埃维克辛公司 | 药物组合物 |
| EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
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| US3949098A (en) * | 1974-06-05 | 1976-04-06 | Nabisco, Inc. | Nutritious orange drink concentrate, process and drink resultant therefrom |
| US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
| US5223244A (en) * | 1988-06-20 | 1993-06-29 | Shiseido Company, Ltd. | Aerosol composition |
| WO1990006060A1 (fr) * | 1988-12-07 | 1990-06-14 | San-Ei Chemical Industries, Ltd. | Procede de preparation d'un concentre de lait/mineraux et boisson mineralisee |
| US5158761A (en) * | 1989-04-05 | 1992-10-27 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| GB9004544D0 (en) * | 1990-03-01 | 1990-04-25 | Leo Pharm Prod Ltd | Novel treatment ii |
| US5087620A (en) * | 1990-05-17 | 1992-02-11 | Bristol-Myers Squibb Co. | Controlled dermal penetration enhancement using imidazoles |
| GB9300763D0 (en) * | 1993-01-15 | 1993-03-03 | Leo Pharm Prod Ltd | Chemical compound |
| FR2701396B1 (fr) * | 1993-02-12 | 1995-04-21 | Oreal | Procédé de stabilisation de vésicules de lipide(s) amphiphile(s) et composition pour application topique contenant lesdites vésicules stabilisées. |
| FR2740038B1 (fr) * | 1995-10-20 | 1998-01-02 | Lafon Labor | Composition pour l'administration transdermique |
| US6126949A (en) * | 1998-04-06 | 2000-10-03 | Bernel Chemical Company, Inc. | Di-behenyl fumarate and its use in dermatological products |
| US6106874A (en) * | 1998-11-18 | 2000-08-22 | Abbott Laboratories | Calcium fortified juice-based nutritional supplement and process of making |
| PT3146969T (pt) * | 1999-04-23 | 2018-10-18 | Leo Pharma As | Composição farmacêutica para aplicação dérmica para uso no tratamento da psoríase compreendendo vitamina d e um corticosteroide |
| US7074747B1 (en) * | 1999-07-01 | 2006-07-11 | Johnson & Johnson Consumer Companies, Inc. | Cleansing compositions |
| KR100844285B1 (ko) * | 2000-10-27 | 2008-07-09 | 레오 파마 에이/에스 | 하나 이상의 비타민 d 또는 비타민 d 동족체 및 하나이상의 코르티코스테로이드를 함유하는 국부용 조성물 |
| US20030059446A1 (en) * | 2001-09-18 | 2003-03-27 | Kulkarni Arun B. | Physically stable sprayable gel composition |
| FR2848454B1 (fr) * | 2002-12-17 | 2007-03-30 | Galderma Res & Dev | Composition pharmaceutique comprenant une association de calcitriol et d'un corticosteroide |
| MXPA05003805A (es) * | 2002-12-17 | 2005-06-08 | Galderma Sa | Composiciones farmaceuticas que comprenden una combinacion de calcitriol y propionato de clobetasol. |
-
2004
- 2004-06-17 FR FR0406613A patent/FR2871696B1/fr not_active Expired - Fee Related
- 2004-10-15 US US10/965,195 patent/US20050281755A1/en not_active Abandoned
-
2005
- 2005-06-15 MX MXPA06014409A patent/MXPA06014409A/es not_active Application Discontinuation
- 2005-06-15 CA CA002567687A patent/CA2567687A1/fr not_active Abandoned
- 2005-06-15 EP EP05777132A patent/EP1778185A1/fr not_active Withdrawn
- 2005-06-15 AU AU2005261571A patent/AU2005261571A1/en not_active Abandoned
- 2005-06-15 CN CNA2005800199993A patent/CN1968681A/zh active Pending
- 2005-06-15 KR KR1020067026292A patent/KR20070024598A/ko not_active Withdrawn
- 2005-06-15 BR BRPI0510840-3A patent/BRPI0510840A/pt not_active Application Discontinuation
- 2005-06-15 RU RU2007101540/15A patent/RU2007101540A/ru unknown
- 2005-06-15 JP JP2007515998A patent/JP2008502663A/ja not_active Withdrawn
- 2005-06-15 WO PCT/FR2005/001496 patent/WO2006005844A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR20070024598A (ko) | 2007-03-02 |
| FR2871696A1 (fr) | 2005-12-23 |
| MXPA06014409A (es) | 2007-02-19 |
| FR2871696B1 (fr) | 2006-11-10 |
| JP2008502663A (ja) | 2008-01-31 |
| EP1778185A1 (fr) | 2007-05-02 |
| US20050281755A1 (en) | 2005-12-22 |
| WO2006005844A1 (fr) | 2006-01-19 |
| RU2007101540A (ru) | 2008-07-27 |
| CN1968681A (zh) | 2007-05-23 |
| AU2005261571A1 (en) | 2006-01-19 |
| CA2567687A1 (fr) | 2006-01-19 |
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