BRPI0514409A - redobra de proteìnas da famìlia de fator de crescimento transformante beta - Google Patents

redobra de proteìnas da famìlia de fator de crescimento transformante beta

Info

Publication number
BRPI0514409A
BRPI0514409A BRPI0514409-4A BRPI0514409A BRPI0514409A BR PI0514409 A BRPI0514409 A BR PI0514409A BR PI0514409 A BRPI0514409 A BR PI0514409A BR PI0514409 A BRPI0514409 A BR PI0514409A
Authority
BR
Brazil
Prior art keywords
growth factor
transforming growth
factor beta
beta family
refolding proteins
Prior art date
Application number
BRPI0514409-4A
Other languages
English (en)
Inventor
Anthony Rossomando
Banjian Gong
R Blake Pepinsky
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of BRPI0514409A publication Critical patent/BRPI0514409A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

REDOBRA DE PROTEìNAS DA FAMìLIA DE FATOR DE CRESCIMENTO TRANSFORMANTE BETA. A presente invenção refere-se a composições e métodos para dobra de proteínas pertencentes à superfamília de fator de crescimento transformante beta que são descritas. As composições e métodos permitem a dobra de tais proteínas quando produzidas em um sistema de expressão que não produziu um produto biologicamente ativo, apropriadamente dobrado.
BRPI0514409-4A 2004-08-19 2005-08-18 redobra de proteìnas da famìlia de fator de crescimento transformante beta BRPI0514409A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60282504P 2004-08-19 2004-08-19
PCT/US2005/029638 WO2006023782A2 (en) 2004-08-19 2005-08-18 Refolding transforming growth factor beta family proteins

Publications (1)

Publication Number Publication Date
BRPI0514409A true BRPI0514409A (pt) 2008-06-10

Family

ID=35968236

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514409-4A BRPI0514409A (pt) 2004-08-19 2005-08-18 redobra de proteìnas da famìlia de fator de crescimento transformante beta

Country Status (15)

Country Link
US (2) US8722862B2 (pt)
EP (1) EP1784203B1 (pt)
JP (1) JP4959566B2 (pt)
KR (1) KR101241551B1 (pt)
CN (2) CN101043899B (pt)
AT (1) ATE472333T1 (pt)
AU (1) AU2005277227B2 (pt)
BR (1) BRPI0514409A (pt)
CA (1) CA2577690C (pt)
DE (1) DE602005022082D1 (pt)
ES (1) ES2349043T3 (pt)
IL (1) IL181312A (pt)
IS (1) IS8609A (pt)
NZ (1) NZ553420A (pt)
WO (1) WO2006023782A2 (pt)

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US8969042B2 (en) 2015-03-03
US20080249287A1 (en) 2008-10-09
US8722862B2 (en) 2014-05-13
JP2008510720A (ja) 2008-04-10
EP1784203A4 (en) 2008-08-20
WO2006023782A2 (en) 2006-03-02
CN101123978A (zh) 2008-02-13
JP4959566B2 (ja) 2012-06-27
ES2349043T3 (es) 2010-12-22
HK1103988A1 (en) 2008-01-04
CA2577690C (en) 2013-08-06
IL181312A (en) 2013-12-31
CA2577690A1 (en) 2006-03-02
IS8609A (is) 2007-02-14
CN101123978B (zh) 2012-12-12
EP1784203A2 (en) 2007-05-16
US20140322752A1 (en) 2014-10-30
ATE472333T1 (de) 2010-07-15
WO2006023782A3 (en) 2007-01-04
KR101241551B1 (ko) 2013-03-11
DE602005022082D1 (de) 2010-08-12
AU2005277227B2 (en) 2011-10-06
KR20070050965A (ko) 2007-05-16
EP1784203B1 (en) 2010-06-30
AU2005277227A1 (en) 2006-03-02
CN101043899A (zh) 2007-09-26
IL181312A0 (en) 2007-07-04
NZ553420A (en) 2010-02-26
CN101043899B (zh) 2011-03-30

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