BRPI0514724A - inibidores da enzima hiv integrase - Google Patents

inibidores da enzima hiv integrase

Info

Publication number
BRPI0514724A
BRPI0514724A BRPI0514724-7A BRPI0514724A BRPI0514724A BR PI0514724 A BRPI0514724 A BR PI0514724A BR PI0514724 A BRPI0514724 A BR PI0514724A BR PI0514724 A BRPI0514724 A BR PI0514724A
Authority
BR
Brazil
Prior art keywords
enzyme inhibitors
hiv integrase
integrase enzyme
compounds
formula
Prior art date
Application number
BRPI0514724-7A
Other languages
English (en)
Inventor
Klaus Dress
Jon Edward Kuehler
Michael Bruno Plewe
Anle Yang
Junhu Zhang
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BRPI0514724A publication Critical patent/BRPI0514724A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

INIBIDORES DA ENZIMA HIV INTEGRASE A presente invenção se refere a compostos da fórmula (I) ou a um sal ou solvato seu farmaceuticamente aceitável, a composições farmacêuticas que compreendem os compostos da fórmula (I) e a métodos do seu uso no tratamento de mamíferos infectados com HIV.
BRPI0514724-7A 2004-09-07 2005-08-26 inibidores da enzima hiv integrase BRPI0514724A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60779104P 2004-09-07 2004-09-07
PCT/IB2005/002967 WO2006027694A1 (en) 2004-09-07 2005-08-26 Inhibitors of the hiv integrase enzyme

Publications (1)

Publication Number Publication Date
BRPI0514724A true BRPI0514724A (pt) 2008-06-24

Family

ID=35539318

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0514724-7A BRPI0514724A (pt) 2004-09-07 2005-08-26 inibidores da enzima hiv integrase

Country Status (7)

Country Link
US (1) US20070232644A1 (pt)
EP (1) EP1802619A1 (pt)
JP (1) JP2008512442A (pt)
BR (1) BRPI0514724A (pt)
CA (1) CA2578841A1 (pt)
MX (1) MX2007002731A (pt)
WO (1) WO2006027694A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8586801A1 (es) 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
DE602005002746T2 (de) 2004-04-26 2008-02-07 Pfizer Inc. Inhibitoren des hiv-integrase-enzyms
CA2564356A1 (en) 2004-04-26 2005-11-03 Pfizer Inc. Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors
CA2623534A1 (en) * 2005-10-03 2007-04-12 Pfizer Products Inc. Inhibitors of the hiv integrase enzyme
JP2009511463A (ja) * 2005-10-07 2009-03-19 ファイザー・プロダクツ・インク Ｈｉｖインテグラーゼ酵素の阻害剤
JP2009543865A (ja) 2006-07-19 2009-12-10 ユニバーシティ オブ ジョージア リサーチ ファウンデーション， インコーポレーテッド ピリジノンジケト酸：併用療法におけるｈｉｖ複製の阻害剤
FR2928150A1 (fr) 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (en) 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
EA201270651A1 (ru) 2009-12-07 2013-01-30 Юниверсити Оф Джорджия Рисерч Фаундейшн, Инк. Карбоксамиды пиридинон гидроксициклопентила: ингибиторы вич интегразы и области терапевтического применения
US8283366B2 (en) * 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8586801A1 (es) * 2002-10-31 2005-02-04 Pfizer Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
CA2564356A1 (en) * 2004-04-26 2005-11-03 Pfizer Inc. Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors

Also Published As

Publication number Publication date
US20070232644A1 (en) 2007-10-04
CA2578841A1 (en) 2006-03-16
WO2006027694A1 (en) 2006-03-16
EP1802619A1 (en) 2007-07-04
JP2008512442A (ja) 2008-04-24
MX2007002731A (es) 2007-04-23

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]