BRPI0603072A - materiais e métodos para produção eficiente de ácido lático - Google Patents

materiais e métodos para produção eficiente de ácido lático

Info

Publication number
BRPI0603072A
BRPI0603072A BRPI0603072-6A BRPI0603072A BRPI0603072A BR PI0603072 A BRPI0603072 A BR PI0603072A BR PI0603072 A BRPI0603072 A BR PI0603072A BR PI0603072 A BRPI0603072 A BR PI0603072A
Authority
BR
Brazil
Prior art keywords
lactic acid
materials
methods
acid production
coli
Prior art date
Application number
BRPI0603072-6A
Other languages
English (en)
Inventor
Shengde Zhou
Lonnie O Neal Ingram
Keelnatham T Shanmugam
Lorraine P Yomano
Tammy B Grabar
Jonathan C Moore
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of BRPI0603072A publication Critical patent/BRPI0603072A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MATERIAIS E MéTODOS PARA PRODUçãO EFICIENTE DE áCIDO LáTICO". A presente invenção refere-se a derivados de Escherichia coli K011 etanologênica construídos para a produção de ácido lático. As E. coli transformadas da invenção são preparadas por deleção dos genes que codificam vias competitivas, seguido por uma seleção à base de crescimento de mutantes com melhor desempenho. Essas E. coli transformadas são úteis para fornecer um suprimento aumentado de ácido lático para uso em aplicações alimentares e industriais.
BRPI0603072-6A 2005-08-10 2006-08-09 materiais e métodos para produção eficiente de ácido lático BRPI0603072A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70688705P 2005-08-10 2005-08-10
US76157606P 2006-01-24 2006-01-24
US79961906P 2006-05-11 2006-05-11

Publications (1)

Publication Number Publication Date
BRPI0603072A true BRPI0603072A (pt) 2007-03-27

Family

ID=37488414

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0603072-6A BRPI0603072A (pt) 2005-08-10 2006-08-09 materiais e métodos para produção eficiente de ácido lático

Country Status (8)

Country Link
US (2) US7629162B2 (pt)
EP (2) EP1760156B1 (pt)
JP (2) JP4991205B2 (pt)
CN (2) CN103396974B (pt)
BR (1) BRPI0603072A (pt)
DK (2) DK2305826T3 (pt)
ES (2) ES2401339T3 (pt)
PL (2) PL2305826T3 (pt)

Families Citing this family (31)

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AU2003287625A1 (en) 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
EP1669460B1 (en) * 2003-09-30 2016-12-21 Mitsui Chemicals, Inc. Biocatalyst for producing d-lactic acid
ES2401339T3 (es) * 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
EP2121915B1 (en) * 2007-03-20 2012-08-08 University of Florida Research Foundation, Inc. Materials and methods for efficient succinate and malate production
US20090082600A1 (en) * 2007-06-06 2009-03-26 Shengde Zhou Native homoethanol Pathway for ethanol production in E. coli
BRPI0913901A2 (pt) 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
CN102333859B (zh) 2008-09-16 2015-04-22 三井化学株式会社 由来自植物的原料生产乳酸的方法及生产乳酸的细菌
WO2010059616A2 (en) * 2008-11-18 2010-05-27 University Of Florida Research Foundation, Inc. Biocatalysts and methods for conversion of hemicellulose hydrolsates to biobased products
WO2010095600A1 (ja) * 2009-02-18 2010-08-26 関西化学機械製作株式会社 ペントースからのホモ乳酸発酵
AU2010232533A1 (en) 2009-04-02 2011-10-13 University Of Florida Research Foundation, Inc. Engineering the pathway for succinate production
WO2011005554A2 (en) 2009-06-23 2011-01-13 Verenium Corporation Recombinant ethanologenic bacteria
CN102575235B (zh) 2009-07-30 2015-05-20 代谢探索者公司 用于通过发酵生产生物化学品的突变甲基乙二醛合酶(mgs)
US8871489B2 (en) 2009-11-18 2014-10-28 Myriant Corporation Metabolic evolution of Escherichia coli strains that produce organic acids
US10017793B2 (en) 2009-11-18 2018-07-10 Myriant Corporation Metabolic evolution of Escherichia coli strains that produce organic acids
EP2501797A4 (en) 2009-11-18 2013-04-17 Myriant Corp TECHNIQUES OF MICROBES FOR THE EFFECTIVE MANUFACTURE OF CHEMICALS
WO2011063157A2 (en) 2009-11-18 2011-05-26 Myriant Technologies Llc Organic acid production in microorganisms by combined reductive and oxidative tricarboxylic acid cycle pathways
JP6061862B2 (ja) 2010-11-22 2017-01-18 カーギル，インコーポレイティド ３‐ヒドロキシプロピオン酸生産用の組成物及び方法
WO2013009679A2 (en) 2011-07-08 2013-01-17 University Of Florida Research Foundation, Inc. Over-expression of a putative oxidoreductase (ucpa) for increasing furfural or 5-hydroxymethylfurfural tolerance
WO2013015770A1 (en) 2011-07-22 2013-01-31 Myriant Corporation Fermentation of glycerol to organic acids
JPWO2014017469A1 (ja) * 2012-07-23 2016-07-11 三井化学株式会社 Ｄ−乳酸の生産方法およびポリマーの生産方法
JP2015536669A (ja) 2012-11-30 2015-12-24 ノボザイムス，インコーポレイティド 組換え酵母による３−ヒドロキシプロピオン酸の生産
KR20140075044A (ko) 2012-12-07 2014-06-19 삼성전자주식회사 불포화 카르복실산의 제조방법
CN104278003B (zh) * 2013-07-12 2018-12-18 中国科学院天津工业生物技术研究所 生产d-乳酸的重组大肠杆菌及其应用
BR112016001778A2 (pt) 2013-07-31 2017-09-05 Novozymes As Célula transgênica de levedura, composição, e, métodos de produção de 3-hp e de produção de ácido acrílico ou um sal do mesmo
EP3194592B1 (en) * 2014-07-23 2020-07-08 Purac Biochem bv Genetically modified (r)-lactic acid producing thermophilic bacteria
EP2977471A1 (en) * 2014-07-23 2016-01-27 PURAC Biochem BV Genetic modification of (S)-lactic acid producing thermophilic bacteria
KR102581464B1 (ko) 2015-05-28 2023-09-21 삼성전자주식회사 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법
JP2017121184A (ja) * 2016-01-04 2017-07-13 花王株式会社 変異リゾプス属菌
EP3752627A4 (en) 2018-02-16 2021-12-22 PTT Global Chemical Public Company Limited MICRO-ORGANISMS AND PROCESSES FOR THE PRODUCTION OF LACTIC ACID
CN109280652A (zh) * 2018-09-13 2019-01-29 四川自豪时代药业有限公司 一种外源高表达乳酸脱氢酶突变体的高密度发酵方法
CN109321590B (zh) * 2018-10-19 2022-06-21 北京化工大学 利用乙酸生产l-乳酸的基因工程菌及其构建方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821093A (en) * 1988-08-31 1998-10-13 University Of Florida Research Foundation, Inc. Recombinant cells that highly express chromosomally-integrated heterologous genes
US4963486A (en) 1989-04-21 1990-10-16 Cornell Research Foundation, Inc. Direct fermentation of corn to L(+)-lactic acid by Rhizopus oryzae
CN1156180A (zh) * 1995-09-05 1997-08-06 底古萨股份公司 用大肠杆菌生产色氨酸
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6849444B2 (en) 2001-04-26 2005-02-01 Archer Daniels Midland Company Strains of Rhizopus oryzae and uses thereof
WO2003102201A2 (en) 2002-05-30 2003-12-11 Cargill Dow Llc Methods and materials for the production of d-lactic acid in yeast
US7300787B2 (en) 2002-07-05 2007-11-27 Archer-Daniels-Midland Company Lactobacillus strains and use thereof in fermentation for L-lactic acid production
AU2003287625A1 (en) * 2002-11-06 2004-06-03 University Of Florida Materials and methods for the efficient production of acetate and other products
US20050112737A1 (en) 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
ES2401339T3 (es) * 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico

Also Published As

Publication number Publication date
US20100203602A1 (en) 2010-08-12
ES2401339T3 (es) 2013-04-18
JP4991205B2 (ja) 2012-08-01
US8426191B2 (en) 2013-04-23
EP1760156A3 (en) 2007-04-04
EP1760156B1 (en) 2012-12-19
ES2573980T3 (es) 2016-06-13
CN1912107B (zh) 2013-03-13
CN103396974B (zh) 2016-12-07
EP1760156A2 (en) 2007-03-07
US20070037265A1 (en) 2007-02-15
PL2305826T3 (pl) 2016-10-31
PL1760156T3 (pl) 2013-05-31
CN1912107A (zh) 2007-02-14
JP2007049993A (ja) 2007-03-01
US7629162B2 (en) 2009-12-08
JP2012010715A (ja) 2012-01-19
DK1760156T3 (da) 2013-03-18
CN103396974A (zh) 2013-11-20
EP1760156A9 (en) 2007-04-25
JP5798441B2 (ja) 2015-10-21
EP2305826A1 (en) 2011-04-06
DK2305826T3 (en) 2016-06-27
EP2305826B1 (en) 2016-03-30

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]