BRPI0606447A - estrutura de receptor de estrogênio - Google Patents

estrutura de receptor de estrogênio

Info

Publication number
BRPI0606447A
BRPI0606447A BRPI0606447-7A BRPI0606447A BRPI0606447A BR PI0606447 A BRPI0606447 A BR PI0606447A BR PI0606447 A BRPI0606447 A BR PI0606447A BR PI0606447 A BRPI0606447 A BR PI0606447A
Authority
BR
Brazil
Prior art keywords
estrogen receptor
receptor structure
ligand polypeptide
polypeptide complexes
crystals
Prior art date
Application number
BRPI0606447-7A
Other languages
English (en)
Inventor
Lidia Mosyak
Zhang Bao Xu
Mark L Stahl
Wah-Tung Hum
William Stuart Somers
Eric Steven Manas
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BRPI0606447A publication Critical patent/BRPI0606447A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ESTRUTURA DE RECEPTOR DE ESTROGêNIO A presente invenção refere-se a ligandos receptores de estrogênio, complexos de polipeptídeo receptor de estrogênio/ligante, cristais de complexos de polipeptídeo receptor de estrogênio/ligante, e métodos relacionados e sistemas de software.
BRPI0606447-7A 2005-01-19 2006-01-18 estrutura de receptor de estrogênio BRPI0606447A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64489705P 2005-01-19 2005-01-19
PCT/US2006/001761 WO2006078733A2 (en) 2005-01-19 2006-01-18 Estrogen receptor structure

Publications (1)

Publication Number Publication Date
BRPI0606447A true BRPI0606447A (pt) 2008-03-11

Family

ID=36283733

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606447-7A BRPI0606447A (pt) 2005-01-19 2006-01-18 estrutura de receptor de estrogênio

Country Status (9)

Country Link
US (1) US7555415B2 (pt)
EP (1) EP1856151A2 (pt)
JP (1) JP2008527045A (pt)
CN (1) CN101142235A (pt)
AU (1) AU2006206534A1 (pt)
BR (1) BRPI0606447A (pt)
CA (1) CA2594890A1 (pt)
MX (1) MX2007008495A (pt)
WO (1) WO2006078733A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6046147B2 (ja) * 2011-09-22 2016-12-14 エクスプレッション、パソロジー、インコーポレイテッドＥｘｐｒｅｓｓｉｏｎ Ｐａｔｈｏｌｏｇｙ， Ｉｎｃ． がんの評価のための多重ｍｒｍアッセイ
SG11201509142UA (en) * 2013-05-06 2015-12-30 Univ Stellenbosch Detecting endocrine disrupting compounds
CN114874326B (zh) * 2022-06-21 2023-01-17 图凌(杭州)生物医药有限公司 一种检测雌激素受体α的单克隆抗体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002506433A (ja) * 1997-06-10 2002-02-26 カロ バイオ アクチェブラーグ エストロゲン・レセプター・リガンド
TW200409759A (en) * 2002-09-25 2004-06-16 Wyeth Corp Substituted 4-(indazol-3-yl)phenols
US6894061B2 (en) * 2002-12-04 2005-05-17 Wyeth Substituted dihydrophenanthridinesulfonamides

Also Published As

Publication number Publication date
WO2006078733A3 (en) 2006-12-21
JP2008527045A (ja) 2008-07-24
MX2007008495A (es) 2007-09-14
CA2594890A1 (en) 2006-07-27
AU2006206534A1 (en) 2006-07-27
US20060160836A1 (en) 2006-07-20
EP1856151A2 (en) 2007-11-21
WO2006078733A2 (en) 2006-07-27
CN101142235A (zh) 2008-03-12
US7555415B2 (en) 2009-06-30

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: ARQUIVAMENTO DEFINITIVO

B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2268 DE 24/06/2014 POR TER SIDO INDEVIDA.