BRPI0606802A2 - uso de compostos de morfolino para a prevenção de contaminação bacteriana - Google Patents

uso de compostos de morfolino para a prevenção de contaminação bacteriana

Info

Publication number
BRPI0606802A2
BRPI0606802A2 BRPI0606802-2A BRPI0606802A BRPI0606802A2 BR PI0606802 A2 BRPI0606802 A2 BR PI0606802A2 BR PI0606802 A BRPI0606802 A BR PI0606802A BR PI0606802 A2 BRPI0606802 A2 BR PI0606802A2
Authority
BR
Brazil
Prior art keywords
bacterial contamination
carbon atoms
prevent bacterial
compounds
morpholino compounds
Prior art date
Application number
BRPI0606802-2A
Other languages
English (en)
Inventor
Jonathan Lane
Olof Torgny Sjidin
Original Assignee
Sinclair Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34307787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0606802(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sinclair Pharmaceuticals Ltd filed Critical Sinclair Pharmaceuticals Ltd
Publication of BRPI0606802A2 publication Critical patent/BRPI0606802A2/pt
Publication of BRPI0606802B1 publication Critical patent/BRPI0606802B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/08—Amines; Quaternary ammonium compounds containing oxygen or sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Eyeglasses (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

USO DE COMPOSTOS DE MORFOLINO PARA A PREVENçãO DE CONTAMINAçãO BACTERIANA. Um composto da fórmula 1: onde R2 12 é um grupo alguila linear ou ramificado contendo 8 a 16 átomos de carbono na posição 2 ou 3 do anel morfolino, e R2 22 é um grupo alquila linear ou ramificado contendo 2 a 10 átomos de carbono, substituído com um grupo hidróxi exceto na posição alfa, a soma dos átomos de carbono nos grupos R2 12 e R2 22 sendo pelo menos 10 e preferivelmente 10 a 20, é utilizado para evitar a formação de biofilme em uma superfície. Os compostos são particularmente úteis para revestimentos ou tratamentos de dispositivos médicos, incluindo stents, cateteres e fios-guia.
BRPI0606802-2A 2005-02-01 2006-02-01 uso de compostos de morfolino para a prevenção de contaminação bacteriana BRPI0606802B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0502046.6 2005-02-01
GBGB0502046.6A GB0502046D0 (en) 2005-02-01 2005-02-01 Method
PCT/GB2006/000335 WO2006082393A1 (en) 2005-02-01 2006-02-01 Use of morpholino compounds for the prevention of bacterial contamination

Publications (2)

Publication Number Publication Date
BRPI0606802A2 true BRPI0606802A2 (pt) 2009-07-14
BRPI0606802B1 BRPI0606802B1 (pt) 2021-02-02

Family

ID=34307787

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606802-2A BRPI0606802B1 (pt) 2005-02-01 2006-02-01 uso de compostos de morfolino para a prevenção de contaminação bacteriana

Country Status (20)

Country Link
US (2) US8999365B2 (pt)
EP (1) EP1850837B1 (pt)
JP (1) JP5209322B2 (pt)
KR (3) KR20070107078A (pt)
CN (1) CN101111221B (pt)
AR (1) AR056267A1 (pt)
AT (1) ATE435011T1 (pt)
AU (1) AU2006210711B2 (pt)
BR (1) BRPI0606802B1 (pt)
CA (1) CA2594836C (pt)
DE (1) DE602006007549D1 (pt)
GB (1) GB0502046D0 (pt)
IL (1) IL184412A0 (pt)
MX (1) MX2007009146A (pt)
NO (1) NO338610B1 (pt)
NZ (1) NZ556323A (pt)
RU (1) RU2375043C2 (pt)
TW (1) TWI365875B (pt)
WO (1) WO2006082393A1 (pt)
ZA (1) ZA200705983B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0502046D0 (en) 2005-02-01 2005-03-09 Sinclair Pharmaceuticals Ltd Method
GB0615814D0 (en) 2006-08-09 2006-09-20 Sinclair Pharmaceuticals Ltd Medicament
GB0714338D0 (en) * 2007-07-23 2007-09-05 Sinclair Pharmaceuticals Ltd method
KR101594202B1 (ko) 2008-09-24 2016-02-15 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． 세포 유착 방지를 위한 펩티드와 조성물 및 그것의 사용 방법
US20150010479A1 (en) 2012-03-20 2015-01-08 Sinclair Pharmaceuticals Limited Treatment of microbial infections
USD908214S1 (en) 2018-07-10 2021-01-19 United States Endoscopy Group, Inc. Tip protector
US11780818B2 (en) 2020-01-31 2023-10-10 You First Services, Inc. Methods of making delmopinol and salts thereof
US20250221412A1 (en) * 2022-03-23 2025-07-10 You First Services, Inc. Methods for irrigation using delmopinol and delmopinol salts

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT320163B (de) * 1973-01-24 1975-01-27 Hurka Wilhelm Desinfektionstüchlein
SU536220A1 (ru) 1974-06-14 1976-11-25 Экспериментально-Конструкторский И Технологический Институт Автомобильной Промышленности Моющее средство дл очстки металлической поверхности
SE439011B (sv) * 1980-03-21 1985-05-28 Ferrosan Ab Morfolinoforeningar, kompositioner innehallande dessa och anvendning derav
DE3017767C2 (de) * 1980-05-09 1984-11-15 Deutsche Gesellschaft für Wiederaufarbeitung von Kernbrennstoffen mbH, 3000 Hannover Schutzbehälter zum Transport, zur Lagerung und zur Strahlungsabschirmung von mit abgebrannten Reaktor-Brennelementen beladenen Brennelementbehältern
ATE11869T1 (de) * 1980-12-18 1985-03-15 Smith & Nephew Ass Sterilisationszubereitungen fuer linsen und ihre anwendung.
US4894221A (en) * 1981-03-19 1990-01-16 Ab Ferrosan Method of treating plaque using morpholine compounds
WO1987005779A1 (en) * 1986-03-28 1987-10-08 Jonah Shacknai Prophylaxis method and composition therefor
NZ233503A (en) * 1989-05-15 1991-06-25 Janssen Pharmaceutica Nv Substituted (thio)morpholinyl and piperazinyl alkylphenol ethers
AU1325792A (en) 1992-02-03 1993-09-01 Samuel Solomon Granulins from leukocytes
US5500206A (en) * 1994-04-29 1996-03-19 The Procter & Gamble Company Oral compositions comprising actinomyces viscosus fimbriae
US6096328A (en) * 1997-06-06 2000-08-01 The Procter & Gamble Company Delivery system for an oral care substance using a strip of material having low flexural stiffness
US6132702A (en) * 1998-02-27 2000-10-17 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US6350438B1 (en) 1998-02-27 2002-02-26 The Procter & Gamble Company Oral care compositions comprising chlorite and methods
US7087661B1 (en) * 1998-09-23 2006-08-08 Cernofina, Llc Safe and effective biofilm inhibitory compounds and health-related uses thereof
CZ20014709A3 (cs) * 1999-07-02 2002-09-11 The Procter & Gamble Company Dávkovací systém pro dodávání látky ústní hygieny do dutiny ústní a způsob dávkování
CN1189012C (zh) * 2000-07-18 2005-02-09 松下电器产业株式会社 图象读取装置及图象处理装置
US6509007B2 (en) * 2001-03-19 2003-01-21 The Procter & Gamble Company Oral care kits and compositions
FI20021126A0 (fi) 2002-06-12 2002-06-12 Pekka Vallittu Antimikrobinen prepreg, komposiitti ja niiden käyttö
US20060105000A1 (en) * 2002-11-21 2006-05-18 J.P.M.E.D. Ltd Compositions for treating infected skin and mucous membrane comprising an anti-microbial agent and an essential oil
ATE483724T1 (de) 2003-02-26 2010-10-15 A & G Pharmaceuticals Inc Verfahren zur erhöhung der ausbreitung von b- zellen
BRPI0410505A (pt) * 2003-05-07 2006-06-20 Dmi Biosciences Inc métodos e produtos para cuidados orais
GB0502046D0 (en) 2005-02-01 2005-03-09 Sinclair Pharmaceuticals Ltd Method
WO2007000924A1 (ja) 2005-06-28 2007-01-04 Osaka University プログラニュリン活性を抑制または促進する物質を含む医薬組成物、およびプログラニュリン活性を抑制または促進する物質のスクリーニング方法
GB0515138D0 (en) 2005-07-22 2005-08-31 Sinclair Pharmaceuticals Acne treatment
JP4994387B2 (ja) 2005-11-22 2012-08-08 シンクレア ファーマシューティカルズ リミテッド 歯肉縁下ポケット感染症の治療
EP2037948B1 (en) 2006-05-30 2016-04-13 Mayo Foundation For Medical Education And Research Detecting and treating dementia
GB0708960D0 (en) 2007-05-09 2007-06-20 Sinclair Pharmaceuticals Ltd Method
GB0714338D0 (en) * 2007-07-23 2007-09-05 Sinclair Pharmaceuticals Ltd method

Also Published As

Publication number Publication date
NZ556323A (en) 2010-06-25
JP2008528160A (ja) 2008-07-31
DE602006007549D1 (de) 2009-08-13
US20080152688A1 (en) 2008-06-26
EP1850837A1 (en) 2007-11-07
US8999365B2 (en) 2015-04-07
KR20150041177A (ko) 2015-04-15
CN101111221B (zh) 2011-07-20
NO20074291L (no) 2007-10-19
IL184412A0 (en) 2007-10-31
RU2375043C2 (ru) 2009-12-10
BRPI0606802B1 (pt) 2021-02-02
JP5209322B2 (ja) 2013-06-12
KR20140032498A (ko) 2014-03-14
AR056267A1 (es) 2007-10-03
TWI365875B (en) 2012-06-11
EP1850837B1 (en) 2009-07-01
KR20070107078A (ko) 2007-11-06
TW200639153A (en) 2006-11-16
CA2594836C (en) 2014-03-11
MX2007009146A (es) 2007-09-06
AU2006210711B2 (en) 2010-05-13
RU2007127905A (ru) 2009-03-10
GB0502046D0 (en) 2005-03-09
ZA200705983B (en) 2009-01-28
CA2594836A1 (en) 2006-08-10
HK1110527A1 (en) 2008-07-18
AU2006210711A1 (en) 2006-08-10
NO338610B1 (no) 2016-09-12
US20150164080A1 (en) 2015-06-18
WO2006082393A1 (en) 2006-08-10
ATE435011T1 (de) 2009-07-15
CN101111221A (zh) 2008-01-23

Similar Documents

Publication Publication Date Title
BR112013031371A2 (pt) glicolipídios de cadeias longas úteis para evitar a deterioração ou a contaminação microbiana de materiais
BR0016555A (pt) Composições farmacêuticas que proporcionam concentrações acrescidas de droga
BRPI0517423A (pt) composto, composição farmacêutica, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com disfunção do glutamato em um animal, e, uso em um composto
GT200400092A (es) Preparacion y uso de derivados de alquilarilo para el tratamiento de la obesidad
SI2020996T1 (sl) Postopek in sestavki za zdravljenje hematološkihmalignosti
TW200641539A (en) Salt suitable for an acid generator and a chemically amplified resist composition containing the same
MY142018A (en) Thiophene derivatives as chk 1 inihibitors
TW200731013A (en) Salt suitable for an acid generator and a chemically amplified resist composition containing the same
BR9812095A (pt) Compostos de indol como inibidores de cox-2
BR0306615A (pt) Composição de cuidado pessoal e composição cosmética
BRPI1012219B8 (pt) produto, substrato, composição farmacêutica, usos de um produto, e de um peptídeo antimicrobiano, métodos para tratar ou prevenir formação de biofilme em um ambiente, e, uso de uma cisteamina
PE20050015A1 (es) Derivados (3-oxo-morfolin-4-il)-fenilamida como inhibidores de factores de coagulacion y compuestos intermediarios en su preparacion
BRPI0606802A2 (pt) uso de compostos de morfolino para a prevenção de contaminação bacteriana
ATE451351T1 (de) Vitamin-d-analogon nel, verfahren und seine verwendung
BRPI0412259A (pt) composto de 1h-pirazol 3,4-dissubstituìdos e seu uso como modulares de quinases dependentes de ciclina (cdk) e quinase-3 de sintase de glicogênio (gsk-3)
DOP2009000272A (es) Metodos y composiciones para inhibir el factor de edema y la adenilil ciclasa y kit
ATE451352T1 (de) Vitamin-d-analog-rak, verfahren dafür und anwendungen davon
BRPI0807749B8 (pt) composto, composição farmacêutica, e, método para a prevenção, tratamento ou melhora de doenças ou condições dérmicas, ou distúrbios de ferida cutânea agudos ou crônicos
BRPI0408353A (pt) composto, composição farmacêutica, métodos para o tratamento de neoplasias suscetìveis e para o tratamento de infecções virais, e, uso de um composto
BR0311460A (pt) Composição farmacêutica de liberação modificada, uso de uma formulação, e, método para tratar um distúrbio cardiovascular em um paciente
BR112022001054A2 (pt) Inibidores enzimáticos
BR112022001390A2 (pt) Inibidores de enzima
BR9914355A (pt) Derivados de mononitrato de isosorbida e sua utilização como agentes vasodilatadores com tolerância reduzida
BR112022010054A2 (pt) Compostos heterocíclicos como inibidores de delta-5 dessaturase e métodos de uso
BRPI0720684A8 (pt) Composto, medicamento, composição farmacêutica que contém e uso do composto

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8 E 13 DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25G Requested change of headquarter approved

Owner name: SINCLAIR PHARMACEUTICALS LIMITED (GB)

B25A Requested transfer of rights approved

Owner name: MAELOR LABORATOIES LIMITED (GB)

B25G Requested change of headquarter approved

Owner name: MAELOR LABORATOIES LIMITED (GB)

B25A Requested transfer of rights approved

Owner name: MERIAL LIMITED (US) ; MERIAL, INC. (US)

B25A Requested transfer of rights approved

Owner name: MERIAL, INC. (US)

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/02/2021, OBSERVADAS AS CONDICOES LEGAIS.