BRPI0616659A8 - droga terapêutica antituberculose, medicamento, e, kit para o tratamento de tuberculose - Google Patents
droga terapêutica antituberculose, medicamento, e, kit para o tratamento de tuberculose Download PDFInfo
- Publication number
- BRPI0616659A8 BRPI0616659A8 BRPI0616659A BRPI0616659A BRPI0616659A8 BR PI0616659 A8 BRPI0616659 A8 BR PI0616659A8 BR PI0616659 A BRPI0616659 A BR PI0616659A BR PI0616659 A BRPI0616659 A BR PI0616659A BR PI0616659 A8 BRPI0616659 A8 BR PI0616659A8
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- tuberculosis
- antituberculosis
- group
- drugs
- Prior art date
Links
- 230000002365 anti-tubercular Effects 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 3
- 201000008827 tuberculosis Diseases 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 125000005843 halogen group Chemical group 0.000 abstract 3
- 229940126585 therapeutic drug Drugs 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940072185 drug for treatment of tuberculosis Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000002916 oxazoles Chemical class 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
- A61K31/06—Phenols the aromatic ring being substituted by nitro groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
droga terapêutica antituberculose, medicamento, e, kit para o tratamento de tuberculose. a presente invenção provê drogas terapêuticas antituberculose com uma potência mais alta. a presente invenção provê também drogas terapêuticas antituberculose contendo compostos de oxazol, representados pela fórmula geral (1): [em que r1 representa um átomo de hidrogênio ou um grupo alquila c1-6, n representa um inteiro de 0-6, e r2 representa a fórmula geral (a) ou os similares, em que r3 representa um grupo fenóxi (pelo menos um grupo selecionado a partir do grupo, que consiste de um átomo de halogênio, um grupo alquila c1-6 opcionalmente substituído por halogênio e um grupo alcóxi c1-6 opcionalmente substituído por halogênio que pode ser substituído no anel fenila) ou os similares, formas opticamente ativas dos mesmos ou sais dos mesmos, e drogas (ii), tais como drogas antituberculose primárias.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005-292461 | 2005-10-05 | ||
| JP2005292461 | 2005-10-05 | ||
| PCT/JP2006/320239 WO2007043542A1 (en) | 2005-10-05 | 2006-10-04 | Antituberculous composition comprising oxazole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0616659A2 BRPI0616659A2 (pt) | 2012-12-25 |
| BRPI0616659A8 true BRPI0616659A8 (pt) | 2018-05-08 |
Family
ID=37561307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0616659A BRPI0616659A8 (pt) | 2005-10-05 | 2006-10-04 | droga terapêutica antituberculose, medicamento, e, kit para o tratamento de tuberculose |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8987304B2 (pt) |
| EP (2) | EP1931425A1 (pt) |
| JP (2) | JP5925065B2 (pt) |
| KR (1) | KR101118942B1 (pt) |
| CN (2) | CN101277740B (pt) |
| AR (1) | AR056872A1 (pt) |
| AU (2) | AU2006300320B2 (pt) |
| BR (1) | BRPI0616659A8 (pt) |
| CA (2) | CA2624497C (pt) |
| IL (1) | IL189944A0 (pt) |
| PH (1) | PH12015501098A1 (pt) |
| RU (2) | RU2434632C2 (pt) |
| SG (1) | SG165361A1 (pt) |
| TW (3) | TW201233389A (pt) |
| UA (1) | UA93888C2 (pt) |
| WO (1) | WO2007043542A1 (pt) |
| ZA (1) | ZA200802883B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2208705B1 (en) * | 2007-09-20 | 2015-06-17 | Kyowa Chemical Industry Co., Ltd. | Calcium secondary phosphate anhydride particle and method for producing the same |
| RU2403041C2 (ru) * | 2008-12-18 | 2010-11-10 | Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") | Лекарственное средство пролонгированного действия с дозированным высвобождением в органы-мишени на основе d-циклосерина для лечения резистентных форм туберкулеза |
| GB201012209D0 (en) * | 2010-05-31 | 2010-09-08 | Ge Healthcare Ltd | In vivo imaging agent |
| HK1218861A1 (zh) | 2013-07-26 | 2017-03-17 | Sanofi | 包含异烟肼颗粒和利福喷汀颗粒的呈可分散的片剂形式的抗结核病的稳定的药物组合物及其制备方法 |
| SG11201510699WA (en) | 2013-07-26 | 2016-01-28 | Sanofi Sa | Antitubercular composition comprising rifampicin, isoniazid, ethambutol and pyrazinamide and its process of preparation. |
| JP6467042B2 (ja) * | 2014-10-21 | 2019-02-06 | カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ | 抗マイコバクテリア剤としての置換１，２，３−トリアゾール−１−イル−メチル−２，３−ジヒドロ−２−メチル−６−ニトロイミダゾ［２，１−ｂ］オキサゾールとその調製方法 |
| RU2606839C1 (ru) * | 2015-10-26 | 2017-01-10 | Федеральное государственное бюджетное учреждение "Национальный исследовательский центр "Курчатовский институт" | Лекарственный препарат противотуберкулезного действия на основе D-циклосерина в виде лиофилизата и способ получения лекарственного препарата |
| GB201519054D0 (en) * | 2015-10-28 | 2015-12-09 | Univ Dundee | Composition |
| RU2627611C2 (ru) * | 2015-10-30 | 2017-08-09 | Акционерное общество "Фармасинтез" (АО "Фармасинтез") | Противотуберкулезная фармацевтическая композиция, содержащая тиоацетазон |
| CN112236141A (zh) * | 2018-06-11 | 2021-01-15 | 大塚制药株式会社 | 包含德拉马尼的组合物 |
| TW202227064A (zh) * | 2020-09-24 | 2022-07-16 | 李建璋 | 使用鈣離子阻斷劑預防肺結核復發 |
| KR102534846B1 (ko) | 2021-12-14 | 2023-05-19 | 재단법인 환동해산업연구원 | 결핵균에 항균 활성을 가지는 해조류 추출물 |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3911263A1 (de) | 1989-04-07 | 1990-10-11 | Saarstickstoff Fatol Gmbh | Kombinationspraeparate |
| ES2095772T3 (es) | 1993-05-05 | 1997-02-16 | Palo Alto Medical Found | Utilizacion de derivados de rifamicina para producir un medicamento destinado al tratamiento de la toxoplasmosis. |
| AR041198A1 (es) * | 2002-10-11 | 2005-05-04 | Otsuka Pharma Co Ltd | Compuesto 2,3-dihidro-6-nitroimidazo[2,1-b] oxaxol, y composiciones farmaceuticas que lo contienen |
| SI1678185T1 (sl) | 2003-10-31 | 2009-02-28 | Otsuka Pharma Co Ltd | Spojine 2,3-dihidro-6-nitroimidazo (2,1-b) oksazol za zdravljenje tuberkuloze |
| NO319656B1 (no) * | 2003-11-03 | 2005-09-05 | Polymers Holding As | Prosess for produksjon av vinylklorid |
| TWI380975B (zh) | 2004-03-25 | 2013-01-01 | Otsuka Pharma Co Ltd | 製造胺基酚類化合物的方法 |
-
2006
- 2006-10-03 TW TW101111055A patent/TW201233389A/zh unknown
- 2006-10-03 TW TW095136754A patent/TWI368509B/zh not_active IP Right Cessation
- 2006-10-03 TW TW102144417A patent/TW201434467A/zh unknown
- 2006-10-04 CA CA2624497A patent/CA2624497C/en not_active Expired - Fee Related
- 2006-10-04 WO PCT/JP2006/320239 patent/WO2007043542A1/en not_active Ceased
- 2006-10-04 KR KR1020087008171A patent/KR101118942B1/ko not_active Expired - Fee Related
- 2006-10-04 SG SG201006561-3A patent/SG165361A1/en unknown
- 2006-10-04 AR ARP060104358A patent/AR056872A1/es unknown
- 2006-10-04 EP EP20060811551 patent/EP1931425A1/en not_active Withdrawn
- 2006-10-04 BR BRPI0616659A patent/BRPI0616659A8/pt not_active IP Right Cessation
- 2006-10-04 ZA ZA200802883A patent/ZA200802883B/xx unknown
- 2006-10-04 EP EP10182000A patent/EP2269694A3/en not_active Withdrawn
- 2006-10-04 AU AU2006300320A patent/AU2006300320B2/en not_active Ceased
- 2006-10-04 CN CN2006800367870A patent/CN101277740B/zh not_active Expired - Fee Related
- 2006-10-04 RU RU2008117427/15A patent/RU2434632C2/ru not_active IP Right Cessation
- 2006-10-04 UA UAA200805407A patent/UA93888C2/uk unknown
- 2006-10-04 US US12/088,867 patent/US8987304B2/en not_active Expired - Fee Related
- 2006-10-04 CN CN2012103986117A patent/CN102895230A/zh active Pending
- 2006-10-04 CA CA2862193A patent/CA2862193C/en not_active Expired - Fee Related
-
2008
- 2008-03-04 IL IL189944A patent/IL189944A0/en unknown
-
2010
- 2010-11-17 AU AU2010241497A patent/AU2010241497A1/en not_active Abandoned
-
2011
- 2011-07-13 RU RU2011129167/15A patent/RU2560676C2/ru not_active Application Discontinuation
-
2012
- 2012-06-21 JP JP2012139686A patent/JP5925065B2/ja not_active Expired - Fee Related
-
2014
- 2014-03-14 JP JP2014051786A patent/JP2014132023A/ja active Pending
-
2015
- 2015-02-13 US US14/622,700 patent/US20150224099A1/en not_active Abandoned
- 2015-05-18 PH PH12015501098A patent/PH12015501098A1/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112012033770A2 (pt) | novo derivado de nicotinamida ou sal do mesmo | |
| DK1519724T3 (da) | Fredericamycin-derivater som lægemidler til behandling af tumorer | |
| BRPI0517803A (pt) | pirazolpirimidinas 1,4-substituìdas como inibidores de cinase | |
| BR0208678A (pt) | Composto, composição farmacêutica, uso de um composto | |
| SE0402735D0 (sv) | Novel compounds | |
| TW200615266A (en) | Organic compounds | |
| BRPI0413452A (pt) | composto, composição farmacêutica, kit, artigo de fabricação, e, métodos de inibir dpp-iv, terapêutico e de tratar um estado de doença, cáncer, distúrbios autoimunes, uma condição einfecção por hiv | |
| UY28369A1 (es) | Agentes terapéuticos | |
| BRPI0510414A (pt) | uso de derivados de quinolina substituìdos para o tratamento de doenças micobacterianas resistentes a fármacos | |
| BRPI0409227C1 (pt) | composto, composição farmacêutica, uso de um composto e processo para a preparação de um composto de fórmula (i) | |
| NO20081482L (no) | Delta- og epsilon-krystallformer for imatinibmesylat | |
| BR0010716A (pt) | Compostos de fenila substituìdos com atividade imunossupressora e composições farmacêuticas | |
| DE60034240D1 (de) | Drogen zur behandlung maligner tumoren | |
| CY1113890T1 (el) | Φαρμακευτικοι συνδυασμοι που περιεχουν βενζοξαζινες για τη θεραπεια νοσων των αναπνευστικων οδων | |
| PH12015501098A1 (en) | Antituberculous composition comprising oxazole compounds | |
| BRPI0418099A (pt) | compostos, composição farmacêutica, e uso de um composto | |
| ATE442349T1 (de) | Diacylglycerol-acyltransferase-hemmer | |
| NO20045486L (no) | Nye forbindelser og deres anvendelse | |
| NO20082112L (no) | 3-Amino-2-arylpropylazaindoler og deres anvendelse | |
| BRPI0510084A (pt) | benzoxazina para tratamento de doenças do trato respiratório | |
| BRPI0515885A (pt) | derivados de ftalazinona, sua preparação e uso como agentes farmacêuticos | |
| EA200900269A1 (ru) | Лекарственные комбинации для лечения заболеваний дыхательных путей | |
| BR0318533A (pt) | azolidinacarbonitrilas e seu uso como inibidores de dpp-iv | |
| DK1970372T3 (da) | Salte af 9-oxoacridin-10-eddikesyre med 1-alkylamino-1-deoxy-polyoler | |
| ATE391710T1 (de) | Substituierte azetidinverbindungen als cyclooxigenase-1-cyclooxygenase-2-inhibitoren und deren herstellung und verwendung als medikament |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO NO ORIGINAL, TRASLADO OU FOTOCOPIA AUTENTICADA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/424 (2006.01), A61P 31/06 (2006.01), A61K |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |