BRPI0619325B8 - célula hospedeira microbiana recombinante e método para produção de isobutanol - Google Patents

célula hospedeira microbiana recombinante e método para produção de isobutanol

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Publication number
BRPI0619325B8
BRPI0619325B8 BRPI0619325A BRPI0619325A BRPI0619325B8 BR PI0619325 B8 BRPI0619325 B8 BR PI0619325B8 BR PI0619325 A BRPI0619325 A BR PI0619325A BR PI0619325 A BRPI0619325 A BR PI0619325A BR PI0619325 B8 BRPI0619325 B8 BR PI0619325B8
Authority
BR
Brazil
Prior art keywords
isobutanol
microbial host
host cell
recombinant microbial
isobutanol production
Prior art date
Application number
BRPI0619325A
Other languages
English (en)
Inventor
C Eliot Andrew
Flint Dennis
K Donaldson Gail
Ann Maggio-Hall Lori
Nagarajan Vasantha
Original Assignee
Butamax Advanced Biofuels Llc
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37835200&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0619325(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Butamax Advanced Biofuels Llc, Du Pont filed Critical Butamax Advanced Biofuels Llc
Publication of BRPI0619325A2 publication Critical patent/BRPI0619325A2/pt
Publication of BRPI0619325B1 publication Critical patent/BRPI0619325B1/pt
Publication of BRPI0619325B8 publication Critical patent/BRPI0619325B8/pt

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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
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    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
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    • C12Y101/01002—Alcohol dehydrogenase (NADP+) (1.1.1.2), i.e. aldehyde reductase
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    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01086—Ketol-acid reductoisomerase (1.1.1.86)
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    • C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04004—3-Methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (1.2.4.4), i.e. branched-chain-alpha-ketoacid dehydrogenase
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    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01003—Aldehyde dehydrogenase (NAD+) (1.2.1.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

células hospedeiras microbianas recombinantes, métodos para produção de isobutanol e meio de fermentação que contém isobutanol. a presente invenção se refere a métodos para produção fermentativa de alcoóis de quatro carbonos. especificamente, butanol, preferencialmente isobutanol é produzido pelo crescimento fermentativo de uma bactéria recombinante que expressa uma via biossintética do isobutanol.
BRPI0619325A 2005-10-26 2006-10-25 célula hospedeira microbiana recombinante e método para produção de isobutanol BRPI0619325B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73029005P 2005-10-26 2005-10-26
US60/730,290 2005-10-26
PCT/US2006/041602 WO2007050671A2 (en) 2005-10-26 2006-10-25 Fermentive production of four carbon alcohols

Publications (3)

Publication Number Publication Date
BRPI0619325A2 BRPI0619325A2 (pt) 2011-10-04
BRPI0619325B1 BRPI0619325B1 (pt) 2020-09-15
BRPI0619325B8 true BRPI0619325B8 (pt) 2020-11-17

Family

ID=37835200

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0619325A BRPI0619325B8 (pt) 2005-10-26 2006-10-25 célula hospedeira microbiana recombinante e método para produção de isobutanol

Country Status (12)

Country Link
US (14) US7851188B2 (pt)
EP (2) EP3301182B1 (pt)
JP (1) JP5276986B2 (pt)
CN (1) CN101297042A (pt)
BR (1) BRPI0619325B8 (pt)
CA (1) CA2622026C (pt)
MX (2) MX359740B (pt)
NZ (2) NZ593809A (pt)
RU (1) RU2394913C2 (pt)
UA (3) UA96928C2 (pt)
WO (1) WO2007050671A2 (pt)
ZA (1) ZA200803755B (pt)

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EP3301182B1 (en) * 2005-10-26 2020-03-18 Butamax (TM) Advanced Biofuels LLC Fermentative production of four carbon alcohols
US8956850B2 (en) * 2008-06-05 2015-02-17 Butamax Advanced Biofuels Llc Enhanced pyruvate to acetolactate conversion in yeast
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
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WO2008098227A2 (en) * 2007-02-09 2008-08-14 The Regents Of The University Of California Biofuel production by recombinant microorganisms
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US8431374B2 (en) * 2007-10-31 2013-04-30 Gevo, Inc. Methods for the economical production of biofuel from biomass
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