BRPI0717633A2 - Anticorpo, composição farmacêutica, e, métodos para detectar uma célula expressando cxcr7 em uma amostra biológica, para tratar, prevenir ou melhorar uma doença e para identificar um modulador de cxcr7 - Google Patents

Anticorpo, composição farmacêutica, e, métodos para detectar uma célula expressando cxcr7 em uma amostra biológica, para tratar, prevenir ou melhorar uma doença e para identificar um modulador de cxcr7

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Publication number
BRPI0717633A2
BRPI0717633A2 BRPI0717633-3A2A BRPI0717633A BRPI0717633A2 BR PI0717633 A2 BRPI0717633 A2 BR PI0717633A2 BR PI0717633 A BRPI0717633 A BR PI0717633A BR PI0717633 A2 BRPI0717633 A2 BR PI0717633A2
Authority
BR
Brazil
Prior art keywords
cxcr7
antibody
disease
identifying
treating
Prior art date
Application number
BRPI0717633-3A2A
Other languages
English (en)
Inventor
Brett Premack
Zhenhua Miao
Mark Penfold
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Publication of BRPI0717633A2 publication Critical patent/BRPI0717633A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07—ORGANIC CHEMISTRY
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    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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BRPI0717633-3A2A 2006-10-18 2007-10-12 Anticorpo, composição farmacêutica, e, métodos para detectar uma célula expressando cxcr7 em uma amostra biológica, para tratar, prevenir ou melhorar uma doença e para identificar um modulador de cxcr7 BRPI0717633A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85274506P 2006-10-18 2006-10-18
US11/869,883 US8088895B2 (en) 2006-10-18 2007-10-10 Antibodies that bind CXCR7 epitopes
PCT/US2007/021927 WO2008048519A2 (en) 2006-10-18 2007-10-12 Antibodies that bind cxcr7 epitopes

Publications (1)

Publication Number Publication Date
BRPI0717633A2 true BRPI0717633A2 (pt) 2014-02-18

Family

ID=39314617

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0717633-3A2A BRPI0717633A2 (pt) 2006-10-18 2007-10-12 Anticorpo, composição farmacêutica, e, métodos para detectar uma célula expressando cxcr7 em uma amostra biológica, para tratar, prevenir ou melhorar uma doença e para identificar um modulador de cxcr7

Country Status (10)

Country Link
US (1) US8088895B2 (pt)
EP (1) EP2086584A4 (pt)
JP (1) JP2010506912A (pt)
KR (1) KR20090088868A (pt)
AU (1) AU2007313274B2 (pt)
BR (1) BRPI0717633A2 (pt)
CA (1) CA2665534A1 (pt)
IL (1) IL198050A0 (pt)
MX (1) MX2009004167A (pt)
WO (1) WO2008048519A2 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012130874A1 (en) 2011-03-28 2012-10-04 Ablynx Nv Bispecific anti-cxcr7 immunoglobulin single variable domains
AU2007336242B2 (en) 2006-12-19 2012-08-30 Ablynx N.V. Amino acid sequences directed against GPCRs and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
US9512236B2 (en) 2006-12-19 2016-12-06 Ablynx N.V. Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
AU2009248049B2 (en) 2008-05-16 2015-07-23 Ablynx N.V. Amino acid sequences directed against CXCR4 and other GPCRs and compounds comprising the same
WO2010126169A1 (ja) * 2009-04-30 2010-11-04 協和発酵キリン株式会社 Alk1阻害剤を有効成分とする血管障害を抑制するための医薬組成物
WO2010141986A1 (en) * 2009-06-09 2010-12-16 Mabdesign Pty Ltd Novel antibodies and uses therefor
US8937164B2 (en) 2010-03-26 2015-01-20 Ablynx N.V. Biological materials related to CXCR7
KR102196374B1 (ko) 2012-11-29 2020-12-31 케모센트릭스, 인크. Cxcr7 길항제
SG10202111844VA (en) 2015-01-09 2021-12-30 Adalta Ltd Cxcr4 binding molecules
CN113149985B (zh) 2015-01-30 2025-01-28 昂克希尔迪克斯有限公司 六氢咪唑并吡啶并嘧啶酮、其类似物和盐、及其治疗用途
CN107614526A (zh) 2015-06-05 2018-01-19 诺华股份有限公司 靶向骨形成蛋白9(bmp9)的抗体及其方法
RS66519B1 (sr) 2016-01-29 2025-03-31 Oncoceutics Inc Modulacija g protein-spregnutog receptora (gpcr) pomoću imipridona
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
JP7590084B2 (ja) 2018-12-12 2024-11-26 ケモセントリックス，インコーポレイティド 癌治療のためのｃｘｃｒ７阻害剤
WO2024054992A1 (en) 2022-09-09 2024-03-14 Bristol-Myers Squibb Company Methods of separating chelator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020166133A1 (en) * 1998-02-10 2002-11-07 Millennium Pharmaceuticals, Inc Neokine protein and nucleic acid molecules and uses therefor
US7253007B2 (en) 2001-11-30 2007-08-07 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
WO2005074645A2 (en) 2004-02-03 2005-08-18 Chemocentryx, Inc. Methods and compositions for modulating angiogenesis
WO2006078780A2 (en) 2005-01-19 2006-07-27 Genzyme Corporation Rdc1 antibodies for the diagnosis of nsclc
ES2434852T3 (es) * 2005-04-21 2013-12-17 Chemocentryx, Inc. Anticuerpos que se unen a CCX-CKR2

Also Published As

Publication number Publication date
JP2010506912A (ja) 2010-03-04
EP2086584A4 (en) 2010-04-07
AU2007313274A1 (en) 2008-04-24
IL198050A0 (en) 2011-08-01
WO2008048519A2 (en) 2008-04-24
MX2009004167A (es) 2009-09-09
CA2665534A1 (en) 2008-04-24
WO2008048519A3 (en) 2008-09-25
US20090022717A1 (en) 2009-01-22
AU2007313274B2 (en) 2012-10-11
KR20090088868A (ko) 2009-08-20
US8088895B2 (en) 2012-01-03
EP2086584A2 (en) 2009-08-12

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