BRPI0810322A2 - "CÉLULA EBx DE AVE TRANSFECTADA, MÉTODO DE PRODUÇÃO DE PELO MENOS UM PRODUTO BIOLÓGICO DE INTERESSE, PRODUTO BIOLÓGICO DE INTERESSE, POPULAÇÃO DE ANTICORPO, ANTICORPOS, USOS DE UM PRODUTO BIOLÓGICO E DE UM ANTICORPO OU UM FRAGMENTO DESTE E COMPOSIÇÃO FARMACÊUTICA" - Google Patents
"CÉLULA EBx DE AVE TRANSFECTADA, MÉTODO DE PRODUÇÃO DE PELO MENOS UM PRODUTO BIOLÓGICO DE INTERESSE, PRODUTO BIOLÓGICO DE INTERESSE, POPULAÇÃO DE ANTICORPO, ANTICORPOS, USOS DE UM PRODUTO BIOLÓGICO E DE UM ANTICORPO OU UM FRAGMENTO DESTE E COMPOSIÇÃO FARMACÊUTICA"Info
- Publication number
- BRPI0810322A2 BRPI0810322A2 BRPI0810322-4A2A BRPI0810322A BRPI0810322A2 BR PI0810322 A2 BRPI0810322 A2 BR PI0810322A2 BR PI0810322 A BRPI0810322 A BR PI0810322A BR PI0810322 A2 BRPI0810322 A2 BR PI0810322A2
- Authority
- BR
- Brazil
- Prior art keywords
- biological product
- interest
- antibody
- ave
- antibodies
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Obesity (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07301058A EP1995309A1 (en) | 2007-05-21 | 2007-05-21 | Recombinant protein production in avian EBx® cells |
| US3278608P | 2008-02-29 | 2008-02-29 | |
| PCT/EP2008/056285 WO2008142124A1 (en) | 2007-05-21 | 2008-05-21 | Recombinant protein production in avian ebx® cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0810322A2 true BRPI0810322A2 (pt) | 2014-10-14 |
Family
ID=38521438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0810322-4A2A BRPI0810322A2 (pt) | 2007-05-21 | 2008-05-21 | "CÉLULA EBx DE AVE TRANSFECTADA, MÉTODO DE PRODUÇÃO DE PELO MENOS UM PRODUTO BIOLÓGICO DE INTERESSE, PRODUTO BIOLÓGICO DE INTERESSE, POPULAÇÃO DE ANTICORPO, ANTICORPOS, USOS DE UM PRODUTO BIOLÓGICO E DE UM ANTICORPO OU UM FRAGMENTO DESTE E COMPOSIÇÃO FARMACÊUTICA" |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20100226912A1 (pt) |
| EP (2) | EP1995309A1 (pt) |
| JP (1) | JP2010529833A (pt) |
| KR (1) | KR20100016540A (pt) |
| CN (1) | CN101688179A (pt) |
| AU (1) | AU2008252902B2 (pt) |
| BR (1) | BRPI0810322A2 (pt) |
| CA (1) | CA2687493A1 (pt) |
| EA (1) | EA017964B1 (pt) |
| IL (1) | IL202213A0 (pt) |
| MX (1) | MX2009012747A (pt) |
| MY (1) | MY159013A (pt) |
| NZ (1) | NZ580820A (pt) |
| WO (1) | WO2008142124A1 (pt) |
| ZA (1) | ZA200908195B (pt) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2539045T3 (es) | 2009-01-19 | 2015-06-25 | Innate Pharma | Anticuerpos anti-KIR3D |
| US8815242B2 (en) | 2009-05-27 | 2014-08-26 | Synageva Biopharma Corp. | Avian derived antibodies |
| WO2011015918A2 (en) * | 2009-08-03 | 2011-02-10 | Avesthagen Limited | Vectors and compounds for expression of recombinant cetuximab |
| WO2011015924A2 (en) * | 2009-08-03 | 2011-02-10 | Avesthagen Limited | Vectors and compounds for expression of recombinant trastuzumab |
| WO2011040526A1 (ja) * | 2009-09-30 | 2011-04-07 | 国立大学法人帯広畜産大学 | α-ガラクトースエピトープ発現ウイルス及びワクチンの作製方法 |
| EP2531592A1 (en) | 2010-02-04 | 2012-12-12 | Vivalis | Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells |
| EP2374816B1 (en) | 2010-04-07 | 2016-09-28 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
| WO2011124635A1 (en) | 2010-04-07 | 2011-10-13 | Humalys | Binding molecules against chikungunya virus and uses thereof |
| EP2603526A1 (en) | 2010-08-13 | 2013-06-19 | Medimmune Limited | Monomeric polypeptides comprising variant fc regions and methods of use |
| WO2012022734A2 (en) | 2010-08-16 | 2012-02-23 | Medimmune Limited | Anti-icam-1 antibodies and methods of use |
| NZ604510A (en) | 2010-08-17 | 2013-10-25 | Csl Ltd | Dilutable biocidal compositions and methods of use |
| WO2012095514A1 (en) * | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
| WO2013000982A1 (en) | 2011-06-27 | 2013-01-03 | Vivalis | Method for screening cells |
| MX2014003689A (es) | 2011-09-30 | 2014-12-05 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpos contra tl1a y sus usos. |
| AU2012327878A1 (en) | 2011-10-28 | 2014-05-29 | Patrys Limited | PAT-LM1 epitopes and methods for using same |
| ES2749349T3 (es) | 2011-11-07 | 2020-03-19 | Medimmune Llc | Proteínas de unión multiespecíficas y multivalentes y usos de las mismas |
| HRP20200744T1 (hr) * | 2011-12-22 | 2020-07-24 | F. Hoffmann - La Roche Ag | Organizacija ekspresijskog vektora, novi postupci generiranja proizvodnje stanica i njihova uporaba za rekombinantnu proizvodnju polipeptida |
| RU2756910C2 (ru) * | 2011-12-22 | 2021-10-06 | Ф. Хоффманн-Ля Рош Аг | Комбинации элементов экспрессионного вектора, новые способы получения клеток-продуцентов и их применение для рекомбинантного получения полипептидов |
| WO2013117647A1 (en) | 2012-02-07 | 2013-08-15 | Innate Pharma | Mica binding agents |
| TWI775096B (zh) | 2012-05-15 | 2022-08-21 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| KR20140015999A (ko) * | 2012-07-27 | 2014-02-07 | 한화케미칼 주식회사 | 신규 MARs 및 이를 이용하여 목적 단백질을 생산하는 방법 |
| US20160194660A1 (en) * | 2012-12-21 | 2016-07-07 | Merck Sharp & Dohme Corp. | Expression vectors for recombinant protein production in mammalian cells |
| PT2951208T (pt) | 2013-02-01 | 2019-12-30 | Univ California | Anticorpos anti-cd83 e sua utilização |
| KR102489953B1 (ko) | 2013-02-07 | 2023-01-20 | 씨에스엘 리미티드 | Il-11r 결합 단백질 및 이의 용도 |
| US9534041B2 (en) | 2013-02-12 | 2017-01-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Monoclonal antibodies that neutralize a norovirus |
| EP2956482B1 (en) | 2013-02-14 | 2017-06-28 | Innate Pharma | Treatment of peripheral t cell lymphoma |
| DK2958941T3 (da) | 2013-02-20 | 2019-06-24 | Innate Pharma | Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom |
| US9101597B2 (en) * | 2013-03-14 | 2015-08-11 | The Administration Of The Tulane Educational Fund | Immunoprotective primary mesenchymal stem cells and methods |
| EP3583950A1 (en) | 2013-05-09 | 2019-12-25 | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services | Single-domain vhh antibodies directed to norovirus gi.1 and gii.4 and their use |
| WO2015050959A1 (en) | 2013-10-01 | 2015-04-09 | Yale University | Anti-kit antibodies and methods of use thereof |
| PT3052192T (pt) | 2013-10-02 | 2020-09-24 | Medimmune Llc | Anticorpos neutralizantes anti-influenza a e suas utilizações |
| KR101591823B1 (ko) * | 2013-12-27 | 2016-02-04 | 재단법인 목암생명공학연구소 | 증가된 유전자 발현능을 갖는 발현벡터 |
| BR112016017817A2 (pt) | 2014-02-06 | 2017-10-10 | Genzyme Corp | composições e métodos para o tratamento e a prevenção de degeneração macular |
| EP3800191B1 (en) | 2014-03-17 | 2025-08-20 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| CA2954780A1 (en) | 2014-07-15 | 2016-01-21 | Medimmune, Llc | Neutralizing anti-influenza b antibodies and uses thereof |
| WO2016030488A1 (en) | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
| CA2963166C (en) | 2014-10-01 | 2023-10-03 | Medimmune Limited | Antibodies to ticagrelor and methods of use |
| CN104531699B (zh) * | 2014-10-09 | 2017-03-15 | 河南农业大学 | 一种增强外源基因表达的猪的ucoe调控元件片段 |
| US10870704B2 (en) | 2014-10-23 | 2020-12-22 | Kira Biotech Pty Limited | CD83 binding proteins and uses thereof |
| WO2016061632A1 (en) | 2014-10-23 | 2016-04-28 | La Trobe University | Fn14-binding proteins and uses thereof |
| WO2016090170A1 (en) | 2014-12-05 | 2016-06-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A potent anti-influenza a neuraminidase subtype n1 antibody |
| ES2784264T3 (es) | 2014-12-17 | 2020-09-23 | Fundacion Para La Investig Medica Aplicada | Construcciones de ácido nucleico y vectores de terapia génica para su uso en el tratamiento de la enfermedad de Wilson y otras afecciones |
| JP6865167B2 (ja) | 2014-12-17 | 2021-04-28 | フンダシオン パラ ラ インベスティガシオン メディカ アプリカダ | ウィルソン病の処置に使用するための核酸構築物及び遺伝子治療ベクター |
| JP7095994B2 (ja) | 2015-03-02 | 2022-07-05 | アドヴェラム バイオテクノロジーズ, インコーポレイテッド | ポリヌクレオチドを網膜錐体に硝子体内送達するための組成物及び方法 |
| EP3960761A1 (en) | 2015-06-01 | 2022-03-02 | MedImmune, LLC | Neutralizing anti-influenza binding molecules and uses thereof |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
| BR112018068678A2 (pt) | 2016-03-15 | 2019-01-15 | Innate Pharma | anticorpos anti-mica |
| CL2016001661A1 (es) * | 2016-06-29 | 2017-03-03 | Univ Chile | Promotor hibrido de ß-actina (de cricetulus griseus) y citomegalovirus (cmv), con región rica en dinucleótidos, citosina-guanina, vectores, líneas celulares, procedimiento para producir proteínas recombinantes. |
| EP3504237A1 (en) | 2016-08-23 | 2019-07-03 | Medimmune Limited | Anti-vegf-a and anti-ang2 antibodies and uses thereof |
| JP6949106B2 (ja) | 2016-08-23 | 2021-10-13 | メディミューン リミテッド | 抗vegf−a抗体ならびにそれらの使用 |
| CN109863175A (zh) | 2016-10-21 | 2019-06-07 | 依奈特制药公司 | 用抗-kir3dl2药剂进行的治疗 |
| GB201710838D0 (en) | 2017-07-05 | 2017-08-16 | Ucl Business Plc | Bispecific antibodies |
| JP7733443B2 (ja) | 2017-09-11 | 2025-09-03 | モナシュ ユニバーシティー | ヒトトロンビン受容体par4に対する結合タンパク質 |
| JP7401432B2 (ja) | 2017-12-01 | 2023-12-19 | エンコーデッド セラピューティクス, インコーポレイテッド | 操作されたdna結合タンパク質 |
| CN108300704B (zh) * | 2018-02-08 | 2022-04-05 | 华农(肇庆)生物产业技术研究院有限公司 | 一种用传代细胞系悬浮培养传染性支气管炎病毒的方法 |
| US20210180084A1 (en) | 2018-05-14 | 2021-06-17 | Vivet Therapeutics | Gene therapy vectors comprising s/mar sequences |
| WO2020034097A1 (en) * | 2018-08-14 | 2020-02-20 | Wuxi Biologics (Shanghai) Co., Ltd. | Transcriptional regulatory element and its use in enhancing the expression of exogenous protein |
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- 2008-05-21 KR KR1020097023743A patent/KR20100016540A/ko not_active Ceased
- 2008-05-21 AU AU2008252902A patent/AU2008252902B2/en not_active Ceased
- 2008-05-21 US US12/601,178 patent/US20100226912A1/en not_active Abandoned
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- 2008-05-21 NZ NZ580820A patent/NZ580820A/en not_active IP Right Cessation
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- 2008-05-21 EA EA200971056A patent/EA017964B1/ru not_active IP Right Cessation
- 2008-05-21 MY MYPI20094777A patent/MY159013A/en unknown
- 2008-05-21 JP JP2010508848A patent/JP2010529833A/ja active Pending
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| JP2010529833A (ja) | 2010-09-02 |
| US20100226912A1 (en) | 2010-09-09 |
| EP1995309A1 (en) | 2008-11-26 |
| MX2009012747A (es) | 2010-02-24 |
| AU2008252902A1 (en) | 2008-11-27 |
| EA017964B1 (ru) | 2013-04-30 |
| KR20100016540A (ko) | 2010-02-12 |
| AU2008252902B2 (en) | 2013-04-04 |
| CA2687493A1 (en) | 2008-11-27 |
| IL202213A0 (en) | 2010-06-16 |
| WO2008142124A1 (en) | 2008-11-27 |
| CN101688179A (zh) | 2010-03-31 |
| NZ580820A (en) | 2012-01-12 |
| MY159013A (en) | 2016-11-30 |
| EA200971056A1 (ru) | 2010-06-30 |
| ZA200908195B (en) | 2010-07-28 |
| EP2152855A1 (en) | 2010-02-17 |
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