BRPI1005176A2 - ensaio de insulina, reagente de ensaio de insulina, anticorpo monoclonal, e, método de triar anticorpos monoclonais. - Google Patents

ensaio de insulina, reagente de ensaio de insulina, anticorpo monoclonal, e, método de triar anticorpos monoclonais.

Info

Publication number
BRPI1005176A2
BRPI1005176A2 BRPI1005176A BRPI1005176A BRPI1005176A2 BR PI1005176 A2 BRPI1005176 A2 BR PI1005176A2 BR PI1005176 A BRPI1005176 A BR PI1005176A BR PI1005176 A BRPI1005176 A BR PI1005176A BR PI1005176 A2 BRPI1005176 A2 BR PI1005176A2
Authority
BR
Brazil
Prior art keywords
insulin assay
monoclonal antibody
screening
monoclonal antibodies
insulin
Prior art date
Application number
BRPI1005176A
Other languages
English (en)
Inventor
Junichi Kondou
Mitsuaki Yamamoto
Tomo Shimizu
Yasushi Nakamura
Original Assignee
Sekisui Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sekisui Medical Co Ltd filed Critical Sekisui Medical Co Ltd
Publication of BRPI1005176A2 publication Critical patent/BRPI1005176A2/pt
Publication of BRPI1005176B1 publication Critical patent/BRPI1005176B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/62—Insulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI1005176-7A 2009-07-21 2010-07-21 ensaio de insulina e reagente de ensaio de insulina BRPI1005176B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009-170292 2009-07-21
JP2009170292 2009-07-21
PCT/JP2010/062261 WO2011010673A1 (ja) 2009-07-21 2010-07-21 インスリン測定方法

Publications (2)

Publication Number Publication Date
BRPI1005176A2 true BRPI1005176A2 (pt) 2016-12-06
BRPI1005176B1 BRPI1005176B1 (pt) 2021-06-08

Family

ID=43499145

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1005176-7A BRPI1005176B1 (pt) 2009-07-21 2010-07-21 ensaio de insulina e reagente de ensaio de insulina

Country Status (11)

Country Link
US (1) US9476891B2 (pt)
EP (1) EP2458378B1 (pt)
JP (2) JP4782249B2 (pt)
KR (1) KR101366353B1 (pt)
CN (1) CN102246039A (pt)
AU (1) AU2010274320B2 (pt)
BR (1) BRPI1005176B1 (pt)
CA (1) CA2739310C (pt)
MX (1) MX2011003927A (pt)
MY (1) MY151976A (pt)
WO (1) WO2011010673A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2853103C (en) * 2011-10-21 2020-01-07 Decimadx, Llc Point-of-care immunoassay for quantitative small analyte detection
EP2885639B1 (en) * 2012-08-17 2019-04-10 MorphoSys AG Complex-specific antibodies and antibody fragments and their use
US20160274092A1 (en) * 2013-03-29 2016-09-22 Sekisui Medical Co., Ltd. Insulin assay
JP6182027B2 (ja) * 2013-09-10 2017-08-16 デンカ生研株式会社 Ｂ型インフルエンザウイルスの測定方法
CN105866420B (zh) * 2015-01-22 2018-11-16 艾托金生物医药（苏州）有限公司 一种检测免疫原的方法和装置
CN106918708A (zh) * 2015-12-28 2017-07-04 北京九强生物技术股份有限公司 一种用于检测胰岛素的竞争法胶乳增强免疫透射比浊试剂盒
JP6862845B2 (ja) * 2016-01-22 2021-04-21 日立化成ダイアグノスティックス・システムズ株式会社 可溶性インターロイキン−２受容体の測定方法及び測定用試薬
AU2017301763B2 (en) * 2016-07-29 2023-07-06 Diazyme Laboratories, Inc. Methods and compositions for assaying vitamin D
SG11202103370RA (en) * 2018-10-09 2021-05-28 Sekisui Medical Co Ltd IMMUNOASSAY AND MEASUREMENT REAGENT FOR LEUCINE-RICH α2 GLYCOPROTEIN
CN111690064A (zh) * 2020-06-24 2020-09-22 合肥天麦生物科技发展有限公司 一种胰岛素原前体蛋白的检测方法及其ppi单克隆抗体的制备方法
CN114195892B (zh) * 2020-09-18 2024-08-13 苏州鲲鹏生物技术有限公司 一种人胰岛素单链前体残留检测控制方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
JPH0619352B2 (ja) * 1985-06-10 1994-03-16 帝人株式会社 ヒト・プロテインｃの測定方法
DE3636724A1 (de) * 1986-10-29 1988-06-23 Joern Dr Med Kekow Enzymimmunoassay (elisa) zur insulinbestimmung im mikrotiterplattensystem
JPH0198968A (ja) * 1987-10-12 1989-04-17 Tosoh Corp ヒス・インスリンの測定方法
JPH01148962A (ja) 1987-12-07 1989-06-12 Tosoh Corp インスリン免疫測定法
DE3806430A1 (de) * 1988-02-29 1989-09-07 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines proteins nach dem prinzip des fluoreszenz-polarisations-immunoassays
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
JPH03118472A (ja) 1989-09-29 1991-05-21 Sekisui Chem Co Ltd インスリン定量方法及び定量試薬
JPH05504841A (ja) * 1990-09-14 1993-07-22 バイオサイト・ダイアグノスティックス・インコーポレイテッド リガンドレセプター及びリガンドのコンプレックスに対する抗体及びリガンド―レセプターアッセーでのそれらの用途
JPH05297000A (ja) * 1992-04-17 1993-11-12 S R L:Kk インスリン抗体の測定方法
JP3479100B2 (ja) * 1993-06-02 2003-12-15 帝国臓器製薬株式会社 免疫化学的簡易半定量方法および装置
US5561049A (en) * 1994-09-21 1996-10-01 Behringwerke Ag Method for detecting antibodies
US6103536A (en) * 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
EP2023141B1 (en) * 2001-07-02 2014-04-09 Sekisui Medical Co., Ltd. Assay reagent comprising carrier particle latex
FI20022048A0 (fi) 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
JP4088328B2 (ja) * 2004-12-28 2008-05-21 第一化学薬品株式会社 抗ヒト可溶性フィブリンモノクローナル抗体及び当該抗体を用いる免疫学的測定方法
JP4448149B2 (ja) * 2007-02-19 2010-04-07 浜松ホトニクス株式会社 蛍光免疫測定方法
WO2009089181A1 (en) * 2008-01-04 2009-07-16 Blodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
JP5115852B2 (ja) 2008-04-28 2013-01-09 国立大学法人電気通信大学 コグニティブ無線通信システム、通信方法、および通信機器
CA2964771C (en) * 2008-09-05 2019-01-15 Sekisui Medical Co., Ltd. Anti-human igm monoclonal antibody and immunoassay using the same

Also Published As

Publication number Publication date
JP2011237442A (ja) 2011-11-24
CA2739310C (en) 2014-07-08
WO2011010673A1 (ja) 2011-01-27
KR20110095349A (ko) 2011-08-24
AU2010274320A1 (en) 2011-01-27
JPWO2011010673A1 (ja) 2013-01-07
JP4782249B2 (ja) 2011-09-28
AU2010274320B2 (en) 2013-08-01
CN102246039A (zh) 2011-11-16
US20110195438A1 (en) 2011-08-11
MY151976A (en) 2014-07-31
CA2739310A1 (en) 2011-01-27
EP2458378A4 (en) 2013-01-02
BRPI1005176B1 (pt) 2021-06-08
US9476891B2 (en) 2016-10-25
JP5661572B2 (ja) 2015-01-28
MX2011003927A (es) 2011-07-20
KR101366353B1 (ko) 2014-02-21
EP2458378A1 (en) 2012-05-30
EP2458378B1 (en) 2017-12-06

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25G Requested change of headquarter approved

Owner name: SEKISUI MEDICAL CO., LTD. (JP)

B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/07/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2784 DE 14-05-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.