BRPI0810613A2 - derivados de tetra-hidrocarbazol como ligantes de receptores acoplados à proteína g - Google Patents

derivados de tetra-hidrocarbazol como ligantes de receptores acoplados à proteína g

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Publication number
BRPI0810613A2
BRPI0810613A2 BRPI0810613A BRPI0810613A BRPI0810613A2 BR PI0810613 A2 BRPI0810613 A2 BR PI0810613A2 BR PI0810613 A BRPI0810613 A BR PI0810613A BR PI0810613 A BRPI0810613 A BR PI0810613A BR PI0810613 A2 BRPI0810613 A2 BR PI0810613A2
Authority
BR
Brazil
Prior art keywords
coupled receptor
protein coupled
receptor ligands
tetrahydrocarbazole derivatives
tetrahydrocarbazole
Prior art date
Application number
BRPI0810613A
Other languages
English (en)
Inventor
Günther Eckhard
Polymeropoulos Emmanuel
Paulini Klaus
Teifel Michael
Schmidt Peter
Baasner Silke
Schuster Tlmamm
Original Assignee
Aeterna Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris Gmbh filed Critical Aeterna Zentaris Gmbh
Publication of BRPI0810613A2 publication Critical patent/BRPI0810613A2/pt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
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  • Psychiatry (AREA)
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BRPI0810613A 2007-04-27 2008-04-25 derivados de tetra-hidrocarbazol como ligantes de receptores acoplados à proteína g BRPI0810613A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91442407P 2007-04-27 2007-04-27
EP07107094A EP1988098A1 (en) 2007-04-27 2007-04-27 Novel Tetrahydrocarbazole Derivatives as Ligands of G-protein Coupled Receptors
PCT/EP2008/055039 WO2008132153A1 (en) 2007-04-27 2008-04-25 Novel tetrahydrocarbazole derivatives as ligands of g-protein coupled receptors

Publications (1)

Publication Number Publication Date
BRPI0810613A2 true BRPI0810613A2 (pt) 2017-05-09

Family

ID=38529386

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810613A BRPI0810613A2 (pt) 2007-04-27 2008-04-25 derivados de tetra-hidrocarbazol como ligantes de receptores acoplados à proteína g

Country Status (17)

Country Link
US (2) US8148546B2 (pt)
EP (2) EP1988098A1 (pt)
JP (1) JP5371956B2 (pt)
KR (1) KR20100015967A (pt)
CN (1) CN101668769B (pt)
AR (1) AR066145A1 (pt)
AU (1) AU2008244305B2 (pt)
BR (1) BRPI0810613A2 (pt)
CA (1) CA2685428A1 (pt)
IL (1) IL200851A0 (pt)
MX (1) MX2009011348A (pt)
NZ (1) NZ579671A (pt)
RU (1) RU2497806C9 (pt)
TW (1) TWI432454B (pt)
UA (1) UA99618C2 (pt)
WO (1) WO2008132153A1 (pt)
ZA (1) ZA200906241B (pt)

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US8748470B2 (en) * 2011-03-17 2014-06-10 The University Of Chicago Methods for treating ovarian cancer by inhibiting fatty acid binding proteins
CN102139107B (zh) * 2011-03-23 2012-10-03 浙江理工大学 神经激肽受体拮抗剂在制备抗癌药物中的用途
CN103142593B (zh) * 2011-03-23 2014-07-16 浙江理工大学 神经激肽受体2的拮抗剂在白血病治疗中的用途
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9815819B2 (en) 2012-06-28 2017-11-14 Novartis Ag Complement pathway modulators and uses thereof
CN104379579B (zh) 2012-06-28 2017-03-08 诺华股份有限公司 吡咯烷衍生物及其作为补体途径调节剂的用途
ES2644700T3 (es) 2012-06-28 2017-11-30 Novartis Ag Derivados de pirrolidina y su uso como moduladores de la ruta del complemento
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