BRPI0816705A2 - Derivatido de 6-pirimidinil-pirimid-2-ona - Google Patents

Derivatido de 6-pirimidinil-pirimid-2-ona

Info

Publication number: BRPI0816705A2
Authority: BR; Brazil
Prior art keywords: pyrimid; ona; pyrimidinyl; derivative; ona derivative
Prior art date: 2007-09-14

Application number

Other languages

English (en)

Inventor

Kenji Fukunaga

Kazutoshi Watanabe

Pascal Barneoud

Jesus Benavides

Jeremy Pratt

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-14

Filing date

2008-09-12

Publication date

2015-03-17

2008-01-11 Priority claimed from EP08290028A external-priority patent/EP2078717A1/en

2008-09-12 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2015-03-17 Publication of BRPI0816705A2 publication Critical patent/BRPI0816705A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Obesity (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Psychology (AREA)
Child & Adolescent Psychology (AREA)
Dermatology (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

BRPI0816705 2007-09-14 2008-09-12 Derivatido de 6-pirimidinil-pirimid-2-ona BRPI0816705A2 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2007269485		2007-09-14
JP2007275713		2007-09-25
EP08290028A EP2078717A1 (en)	2008-01-11	2008-01-11	6-Pyrimidinyl-pyrimid-2-one derivative
PCT/JP2008/066936 WO2009035162A1 (en)	2007-09-14	2008-09-12	6-pyrimidinyl-pyrimid-2-one derivative

Publications (1)

Publication Number	Publication Date
BRPI0816705A2 true BRPI0816705A2 (pt)	2015-03-17

Family

ID=39874051

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816705 BRPI0816705A2 (pt)	2007-09-14	2008-09-12	Derivatido de 6-pirimidinil-pirimid-2-ona

Country Status (15)

Country	Link
US (2)	US8198437B2 (pt)
EP (1)	EP2193129B1 (pt)
JP (1)	JP5249320B2 (pt)
KR (1)	KR20100074182A (pt)
CN (1)	CN101883770A (pt)
AR (1)	AR068439A1 (pt)
AU (1)	AU2008297817A1 (pt)
BR (1)	BRPI0816705A2 (pt)
CA (1)	CA2698819A1 (pt)
EA (1)	EA201070367A1 (pt)
MX (1)	MX2010002765A (pt)
NZ (1)	NZ584277A (pt)
TW (1)	TW200927134A (pt)
WO (1)	WO2009035162A1 (pt)
ZA (1)	ZA201002213B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200813015A (en) *	2006-03-15	2008-03-16	Mitsubishi Pharma Corp	2-(cyclic amino)-pyrimidone derivatives
EP2193129B1 (en)	2007-09-14	2012-10-24	Mitsubishi Tanabe Pharma Corporation	6-pyrimidinyl-pyrimid-2-one derivative
TW201043618A (en)	2009-03-10	2010-12-16	Sanofi Aventis	Intermediate compound for synthesizing pharmaceutical agent and production method thereof
EP2464632A1 (en)	2009-08-13	2012-06-20	Mitsubishi Tanabe Pharma Corporation	Pyrimidone derivatives used as tau protein kinase 1 inhibitors
EP2464639A1 (en) *	2009-08-13	2012-06-20	Mitsubishi Tanabe Pharma Corporation	Pyrimidone derivatives used as tau protein kinase 1 inhibitors
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP3453706A1 (en)	2017-09-08	2019-03-13	Basf Se	Pesticidal imidazole compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2116460A1 (en)	1993-03-02	1994-09-03	Mitsubishi Chemical Corporation	Preventive or therapeutic agents for alzheimer's disease, a screening method of alzheimer's disease and tau-protein kinase i originated from human being
MXPA04002661A (es)	2001-09-21	2004-11-22	Sanofi Aventis	Derivados de pirimidona 4, 3-sustituida.
ES2323576T3 (es) *	2001-09-21	2009-07-21	Mitsubishi Tanabe Pharma Corporation	Derivados de 4-pirimidona 3-sustituida.
TWI357408B (en) *	2003-03-26	2012-02-01	Mitsubishi Tanabe Pharma Corp	3-substituted-4-pyrimidone derivatives
AR050865A1 (es) *	2004-09-09	2006-11-29	Sanofi Aventis	Derivados de 2- morfolino-4-pirimidona
JP5186213B2 (ja)	2004-09-29	2013-04-17	田辺三菱製薬株式会社	タウプロテインキナーゼ１阻害剤としての６−ピリジニル−４−ピリミドン誘導体
TW200740779A (en)	2005-07-22	2007-11-01	Mitsubishi Pharma Corp	Intermediate compound for synthesizing pharmaceutical agent and production method thereof
TW200813015A (en) *	2006-03-15	2008-03-16	Mitsubishi Pharma Corp	2-(cyclic amino)-pyrimidone derivatives
AR064660A1 (es) *	2006-12-26	2009-04-15	Mitsubishi Tanabe Pharma Corp	Derivados de pirimidinona 6-heterociclica 2-sustituida, medicamentos que los contienen y usos para prevenir y/o tratar enfermedades neurodegenerativas entre otras
EP2193129B1 (en)	2007-09-14	2012-10-24	Mitsubishi Tanabe Pharma Corporation	6-pyrimidinyl-pyrimid-2-one derivative
AR076014A1 (es)	2009-04-02	2011-05-11	Sanofi Aventis	Derivados de 3- (1,4) oxazepan -4-pirimidona

2008
- 2008-09-12 EP EP08831179A patent/EP2193129B1/en active Active
- 2008-09-12 KR KR1020107008065A patent/KR20100074182A/ko not_active Withdrawn
- 2008-09-12 BR BRPI0816705 patent/BRPI0816705A2/pt not_active IP Right Cessation
- 2008-09-12 AU AU2008297817A patent/AU2008297817A1/en not_active Abandoned
- 2008-09-12 AR ARP080103982A patent/AR068439A1/es not_active Application Discontinuation
- 2008-09-12 MX MX2010002765A patent/MX2010002765A/es not_active Application Discontinuation
- 2008-09-12 US US12/677,213 patent/US8198437B2/en not_active Expired - Fee Related
- 2008-09-12 WO PCT/JP2008/066936 patent/WO2009035162A1/en not_active Ceased
- 2008-09-12 CA CA2698819A patent/CA2698819A1/en not_active Abandoned
- 2008-09-12 JP JP2010510582A patent/JP5249320B2/ja not_active Expired - Fee Related
- 2008-09-12 EA EA201070367A patent/EA201070367A1/ru unknown
- 2008-09-12 TW TW097135175A patent/TW200927134A/zh unknown
- 2008-09-12 NZ NZ584277A patent/NZ584277A/en not_active IP Right Cessation
- 2008-09-12 CN CN2008801137447A patent/CN101883770A/zh active Pending
2010
- 2010-03-29 ZA ZA2010/02213A patent/ZA201002213B/en unknown
2012
- 2012-05-09 US US13/467,302 patent/US8518939B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP2010538969A (ja)	2010-12-16
KR20100074182A (ko)	2010-07-01
US8518939B2 (en)	2013-08-27
MX2010002765A (es)	2010-05-19
ZA201002213B (en)	2011-06-29
US20110021773A1 (en)	2011-01-27
TW200927134A (en)	2009-07-01
US8198437B2 (en)	2012-06-12
EP2193129B1 (en)	2012-10-24
US20120252812A1 (en)	2012-10-04
EA201070367A1 (ru)	2010-08-30
EP2193129A1 (en)	2010-06-09
AU2008297817A1 (en)	2009-03-19
CA2698819A1 (en)	2009-03-19
CN101883770A (zh)	2010-11-10
NZ584277A (en)	2011-11-25
WO2009035162A1 (en)	2009-03-19
AR068439A1 (es)	2009-11-18
JP5249320B2 (ja)	2013-07-31

Publication	Publication Date	Title
CY2024031I2 (el)	2026-02-25	Παραγωγο 4-πυριμιδινοσουλφαμιδης
EP2226315A4 (en)	2012-01-25	2-aminoquinazoline DERIVATIVE
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
EP2376493A4 (en)	2012-05-30	DIHYDROPYRIMIDOPYRIMIDINDERIVAT
EP2380877A4 (en)	2012-06-27	PYRIDINE-3-CARBONSÄUREAMIDDERIVAT
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
DK2209786T3 (da)	2013-06-03	Pyrimidinsubstituerede purinderivater
EP2170350A4 (en)	2011-09-28	SUBSTITUTED IMIDAZOHETEROCYCLES
ATE542825T1 (de)	2012-02-15	Substituierte piperidino-dihydrothienopyrimidine
BRPI0818380A2 (pt)	2014-10-07	Combinação de herbicida-protetor
BRPI0813836A2 (pt)	2015-01-06	Derivados pirazólicos
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
EP2072519A4 (en)	2009-10-21	DIARYLKETIMINDERIVAT
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
EP2336132A4 (en)	2012-03-21	MORPHOLINPURINDERIVAT
DK2152370T3 (da)	2011-08-15	Aryletherpyridazinonderivater
BRPI0814718A2 (pt)	2015-02-24	Derivados de isoxazol-imidazol
ATE546446T1 (de)	2012-03-15	5-aminocyclylmethyl-oxazolidin-2-eins-derivativ
EP2058570A4 (en)	2013-01-16	Marine hose
BRPI0909425A2 (pt)	2015-12-01	derivado de hidroxiquinoxalinacarboxamida

Legal Events

Date	Code	Title	Description
2015-12-01	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.