BRPI0812865A2 - Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados. - Google Patents

Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados.

Info

Publication number
BRPI0812865A2
BRPI0812865A2 BRPI0812865-0A2A BRPI0812865A BRPI0812865A2 BR PI0812865 A2 BRPI0812865 A2 BR PI0812865A2 BR PI0812865 A BRPI0812865 A BR PI0812865A BR PI0812865 A2 BRPI0812865 A2 BR PI0812865A2
Authority
BR
Brazil
Prior art keywords
derivatives
anylinopurine
cytokinine
oxidase
preparations containing
Prior art date
Application number
BRPI0812865-0A2A
Other languages
English (en)
Inventor
Lukas Spichal
Marketa Gemrotova
Marek Zatloukal
Jitka Frebortova
Petr Galuszka
Tomas Werner
Thomas Schmulling
Karel Dolezal
Miroslav Strnad
Original Assignee
Univ Berlin Freie
Univerzita Palackecho V Olomouci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Berlin Freie, Univerzita Palackecho V Olomouci filed Critical Univ Berlin Freie
Publication of BRPI0812865A2 publication Critical patent/BRPI0812865A2/pt
Publication of BRPI0812865B1 publication Critical patent/BRPI0812865B1/pt
Publication of BRPI0812865B8 publication Critical patent/BRPI0812865B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BRPI0812865A 2007-07-04 2008-07-02 derivados de 6-anilinopurina substituída BRPI0812865B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20070453A CZ302225B6 (cs) 2007-07-04 2007-07-04 Substituované 6-anilinopurinové deriváty jako inhibitory cytokinin oxidasy a prípravky obsahující tyto slouceniny
PCT/CZ2008/000074 WO2009003428A2 (en) 2007-07-04 2008-07-02 Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase/dehydrogenase and preparations containing these derivatives

Publications (3)

Publication Number Publication Date
BRPI0812865A2 true BRPI0812865A2 (pt) 2014-10-07
BRPI0812865B1 BRPI0812865B1 (pt) 2019-09-03
BRPI0812865B8 BRPI0812865B8 (pt) 2022-09-20

Family

ID=40226563

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812865A BRPI0812865B8 (pt) 2007-07-04 2008-07-02 derivados de 6-anilinopurina substituída

Country Status (13)

Country Link
US (1) US8222260B2 (pt)
EP (1) EP2173173B1 (pt)
JP (1) JP5539866B2 (pt)
AU (1) AU2008271800B2 (pt)
BR (1) BRPI0812865B8 (pt)
CA (1) CA2691625C (pt)
CZ (1) CZ302225B6 (pt)
DK (1) DK2173173T3 (pt)
ES (1) ES2431926T3 (pt)
NZ (1) NZ582642A (pt)
PL (1) PL2173173T3 (pt)
PT (1) PT2173173E (pt)
WO (1) WO2009003428A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5584133B2 (ja) * 2008-10-20 2014-09-03 株式会社理研グリーン イネ科雑草用の生育調節剤
CZ306894B6 (cs) 2013-02-08 2017-08-30 Univerzita PalackĂ©ho v Olomouci 2-Substituované-6-biarylmethylamino-9-cyklopentyl-9H-purinové deriváty, jejich použití jako léčiva a farmaceutické přípravky tyto sloučeniny obsahující
US9938279B2 (en) * 2013-04-09 2018-04-10 Energenesis Biomedical Co., Ltd Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK)
CA2932027C (en) 2013-12-11 2021-10-19 Fine Agrochemicals Ltd. Water-dispersible plant growth regulating concentrate and processes for making and using same
WO2016095881A1 (en) 2014-12-15 2016-06-23 Univerzita Palackeho V Olomouci Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress
ITUB20153115A1 (it) * 2015-08-13 2017-02-13 Diapath S P A Nuova composizione fissativa per campioni di materiale biologico.
GB201610264D0 (en) * 2016-06-13 2016-07-27 Syngenta Participations Ag Pesticidal compositions
MY190800A (en) * 2016-06-14 2022-05-12 Syngenta Participations Ag Use of 6-anilino purine derivatives to improve heat stress tolerance of rice seedlings
MY198859A (en) 2016-06-14 2023-10-02 Syngenta Participations Ag Abiotic stress tolerance
EP3528816A4 (en) * 2016-10-21 2020-04-08 Nimbus Lakshmi, Inc. TYK2 INHIBITORS AND USES THEREOF
WO2018217884A1 (en) 2017-05-23 2018-11-29 Regents Of The University Of Minnesota Antibacterial agents including histidine kinase inhibitors
CN111801015B (zh) 2017-12-12 2022-03-18 先正达参股股份有限公司 植物生长调节
CN108371662B (zh) * 2018-02-06 2023-03-03 中国药科大学 一种五元杂环并嘧啶类化合物的应用
CN110407836B (zh) * 2019-08-15 2022-03-29 沈阳化工研究院有限公司 一种9-（2-甲氧基乙基）-9h-嘌呤-6-胺衍生物及其应用
CN110642859B (zh) * 2019-10-11 2021-11-09 青岛科技大学 一种含嘧啶硫酮嘌呤类化合物及其用途
CZ309368B6 (cs) 2020-05-17 2022-10-12 Univerzita Palackého v Olomouci Mesylátové soli heterocyklických cytokininů, přípravky obsahující tyto deriváty a jejich použití
EP4178959B1 (en) 2020-07-13 2025-09-10 Univerzita Palackého v Olomouci Nitrogen heterocyclic cytokinin derivatives, compositions containing these derivatives and use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118753A (en) * 1961-04-14 1964-01-21 Shive William Plant growth stimulating composition and method employing mixtures of a gibberellic acid and purine compound
EP0155911A1 (de) * 1984-03-19 1985-09-25 Ciba-Geigy Ag Purinderivate zur Regulierung des Pflanzenwachstums
WO1992020341A1 (en) * 1991-05-16 1992-11-26 Senetek, Plc Method and composition for ameliorating the adverse effects of aging
DE69324244T2 (de) * 1992-01-06 1999-09-30 The Wellcome Foundation Ltd., Greenford Therapeutische nukleoside der 2',3'-dideoxy-3'-fluor -purin reihe
AU7296896A (en) * 1995-11-01 1997-05-22 Novartis Ag Purine derivatives and processes for their preparation
DE69706530T2 (de) 1996-03-15 2002-04-18 Syngenta Participations Ag, Basel Herbizide synergistische zusammensetzung und verfahren zur unkrautbekämpfung
CZ294535B6 (cs) * 2001-08-02 2005-01-12 Ústav Experimentální Botaniky Avčr Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
US20070161582A1 (en) * 2003-08-08 2007-07-12 Dusan Mijikovic Pharmaceutical compositions and methods for metabolic modulation
MXPA06001758A (es) * 2003-08-15 2006-08-11 Irm Llc Anilino purinas sustituidas en la posicion 6 utiles como inhibidores de rtk.
GB0407723D0 (en) * 2004-04-05 2004-05-12 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
AU2008271800B2 (en) 2013-10-17
PT2173173E (pt) 2013-10-22
EP2173173B1 (en) 2013-07-24
NZ582642A (en) 2011-06-30
US20100190806A1 (en) 2010-07-29
BRPI0812865B8 (pt) 2022-09-20
WO2009003428A3 (en) 2009-09-03
BRPI0812865B1 (pt) 2019-09-03
JP5539866B2 (ja) 2014-07-02
ES2431926T3 (es) 2013-11-28
PL2173173T3 (pl) 2014-07-31
US8222260B2 (en) 2012-07-17
JP2010531818A (ja) 2010-09-30
CZ2007453A3 (cs) 2009-02-11
CA2691625A1 (en) 2009-01-08
WO2009003428A2 (en) 2009-01-08
CA2691625C (en) 2014-12-09
DK2173173T3 (da) 2013-11-04
CZ302225B6 (cs) 2010-12-29
EP2173173A2 (en) 2010-04-14
AU2008271800A1 (en) 2009-01-08

Similar Documents

Publication Publication Date Title
BRPI0812865A2 (pt) Derivados de 6-anilinopurina substituída como inibidores de citoquinina oxidase/desidrogenase e preparações contendo esses derivados.
LTC2137143I2 (lt) Pleuromutilino dariniai, skirti mikrobų sukeltų ligų gydymui
LTPA2018510I1 (lt) Dioksa-biciklo[3.2.1]oktan-2,3,4-triolio dariniai
BRPI1015568A2 (pt) derivados de imidazolidin-2-ona 1,3-dissubstituído como inibidores de cyp 17.
CR10400A (es) Derivados de lactamas de ciclohexilpirazol como inhibidores de 11-beta -hidroxiesteroide deshidrogenasa 1
GT200900014A (es) Derivados de i-(-d-glucopiranosil)-3-(4-ciclopropilfenilmetil)-4-halogeno indoly uso de los mismos como inhibidores de los transportadores de glucosa dependientes de sodio.
BRPI0718266A2 (pt) Compostos heterocíclicos como agentes anti-inflamatórios.
IL210195A0 (en) Benzoxazines, benzothazines, and related compounds having nos inhibitory activity
DK2545918T3 (da) Pyrazolopyridinderivater som NADPH-oxidaseinhibitorer
BRPI0922073A2 (pt) Compostos de éter com heterociclo de 5 membros contendo nitrogênio e usos dos mesmos.
SMAP201000115A (it) Nuovi composti eterociclici e loro usi.
MX2009004883A (es) Piridil sulfoximinas multi-substituidas y su uso como insecticidas.
BRPI0919328A2 (pt) derivados de pirazolo piridina como inibidores de nadph oxidase
BRPI1016150A2 (pt) compostos heterocíclicos e seus usos.
IL211889A (en) Pyrazolo pyridine derivatives, preparations containing them and their use as nadph oxidase inhibitors
WO2011084803A3 (en) Coloring agents and methods of use thereof
BRPI1015967A2 (pt) "unidade de dobradiça, e, peça de mobília."
BRPI1016117A8 (pt) derivados de isoxazol-isoxazol e isoxazol-isotiazol.
BRPI0807897A2 (pt) Derivados de pirimidina-2,4-diamina e seus usos como inibidores de jak2 quinase.
DK2108260T3 (da) Sammensætning med biocid aktivitet til vandige præparater
ATE545417T1 (de) Pyrazoloä3,4-büpyridin-derivate als phosphodiesterasehemmer
BRPI0917446A2 (pt) derivados de acilaminobenzamida.
DK2344486T3 (da) Alkylthiazolcarbamatderivater, fremstilling deraf og anvendelse deraf som hæmmere af enzymet FAAH
BRPI0916363A2 (pt) derivados de 4,5-di-hidro-oxazol-2-ila
WO2011115809A3 (en) High energy radiation insensitive analyte sensors

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: UNIVERZITA PALACKECHO V OLOMOUCI (CZ)

B25A Requested transfer of rights approved

Owner name: SYNGENTA PARTICIPATIONS AG (CH)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/07/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B15V Prolongation of time limit allowed
B22E Other requirements [chapter 22.5 patent gazette]

Free format text: FORMULADA EXIGENCIA PARA ADEQUACAO OU CUMPRIMENTO DE DISPOSICOES LEGAIS NO PRAZO DE 60 (SESSENTA) DIAS DESTA DATA.

B16B Notification of grant cancelled [chapter 16.2 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 16.3 NA RPI NO 2629 DE 25/05/2021 POR TER SIDO INDEVIDA.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: RETIFICACAO REF. RPI 2539, DE 03/09/2019. PRAZO DE VALIDADE: 10 ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME A ADI 5.529/DF, COM APOSTILAMENTO DO PRAZO DE VALIDADE DA PROTECAO DA MATERIA RELATIVA A PRODUTOS E PROCESSOS FARMACEUTICOS E EQUIPAMENTOS E/OU MATERIAIS DE USO EM SAUDE, PARA APLICACAO EM HUMANOS.

B25A Requested transfer of rights approved

Owner name: SYNGENTA CROP PROTECTION AG (CH)