BRPI0814339A2 - composição farmacêutica, kit para a preparação da composição farmacêutica, conjugado, e, métodos de formação de imagem óptica in vivo do corpo de mamíferos, e de detecção, estabilização, diagnóstico, monitoramento do progresso da doença ou monitoramento do tratamento de um estado doentio do corpon dos mamíferos - Google Patents

composição farmacêutica, kit para a preparação da composição farmacêutica, conjugado, e, métodos de formação de imagem óptica in vivo do corpo de mamíferos, e de detecção, estabilização, diagnóstico, monitoramento do progresso da doença ou monitoramento do tratamento de um estado doentio do corpon dos mamíferos

Info

Publication number
BRPI0814339A2
BRPI0814339A2 BRPI0814339A BRPI0814339A BRPI0814339A2 BR PI0814339 A2 BRPI0814339 A2 BR PI0814339A2 BR PI0814339 A BRPI0814339 A BR PI0814339A BR PI0814339 A BRPI0814339 A BR PI0814339A BR PI0814339 A2 BRPI0814339 A2 BR PI0814339A2
Authority
BR
Brazil
Prior art keywords
monitoring
pharmaceutical composition
conjugate
stabilization
diagnosis
Prior art date
Application number
BRPI0814339A
Other languages
English (en)
Inventor
John Healey Andrew
James Domett Nairne Robert
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2007/002907 external-priority patent/WO2008015415A2/en
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BRPI0814339A2 publication Critical patent/BRPI0814339A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0056—Peptides, proteins, polyamino acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4842—Monitoring progression or stage of a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Endoscopes (AREA)
  • Peptides Or Proteins (AREA)
BRPI0814339A 2007-07-31 2008-07-29 composição farmacêutica, kit para a preparação da composição farmacêutica, conjugado, e, métodos de formação de imagem óptica in vivo do corpo de mamíferos, e de detecção, estabilização, diagnóstico, monitoramento do progresso da doença ou monitoramento do tratamento de um estado doentio do corpon dos mamíferos BRPI0814339A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/GB2007/002907 WO2008015415A2 (en) 2006-07-31 2007-07-31 Asymmetric fluoro-substituted polymethine dyes
GBGB0718957.4A GB0718957D0 (en) 2007-09-28 2007-09-28 Optical imaging agents
US97681707P 2007-10-02 2007-10-02
PCT/EP2008/059942 WO2009016181A2 (en) 2007-07-31 2008-07-29 Optical imaging agents

Publications (1)

Publication Number Publication Date
BRPI0814339A2 true BRPI0814339A2 (pt) 2017-10-24

Family

ID=38701832

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814339A BRPI0814339A2 (pt) 2007-07-31 2008-07-29 composição farmacêutica, kit para a preparação da composição farmacêutica, conjugado, e, métodos de formação de imagem óptica in vivo do corpo de mamíferos, e de detecção, estabilização, diagnóstico, monitoramento do progresso da doença ou monitoramento do tratamento de um estado doentio do corpon dos mamíferos

Country Status (12)

Country Link
US (1) US20100196282A1 (pt)
EP (1) EP2190931A2 (pt)
JP (1) JP2010534712A (pt)
KR (1) KR20100051640A (pt)
CN (1) CN101952369A (pt)
AU (1) AU2008281818A1 (pt)
BR (1) BRPI0814339A2 (pt)
CA (1) CA2694102A1 (pt)
GB (1) GB0718957D0 (pt)
MX (1) MX2010001247A (pt)
RU (1) RU2484111C9 (pt)
WO (1) WO2009016181A2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
EP2588541A1 (en) * 2010-06-29 2013-05-08 GE Healthcare AS Dye compositions and dye syntheses
GB201010878D0 (en) * 2010-06-29 2010-08-11 Ge Healthcare As Dye compositiion and dye syntheses
EP2598174B1 (de) * 2010-07-30 2019-03-27 SmartDyeLivery GmbH Messverfahren zur bestimmung einer organfunktion
GB201013808D0 (en) 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
US10053447B2 (en) 2010-12-21 2018-08-21 Pierce Biotechnology, Inc Fluorescent compounds
US8889884B1 (en) 2011-07-14 2014-11-18 Pierce Biotechnology, Inc. Phosphine derivatives of fluorescent compounds
US9249307B2 (en) 2011-08-16 2016-02-02 Pierce Biotechnology, Inc. Benzocyanine compounds
US9751868B2 (en) 2012-02-28 2017-09-05 Pierce Biotechnology, Inc. Benzocyanine compounds
CN104395306B (zh) 2012-03-02 2019-04-23 皮尔斯生物科技有限公司 作为生物分子的标记染料的吲哚衍生物
US9676787B2 (en) 2012-08-28 2017-06-13 Pierce Biotechnology, Inc. Benzopyrylium compounds
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
JP2016156804A (ja) * 2015-12-25 2016-09-01 ユニヴェルシテッツクリニクム イエーナ 臓器機能を判定するための測定方法

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
ATE264694T1 (de) * 1995-01-30 2004-05-15 Daiichi Pure Chemicals Co Ltd Diagnostisches markierungsmittel
DE19534177A1 (de) * 1995-09-15 1997-03-20 Merck Patent Gmbh Cyclische Adhäsionsinhibitoren
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
AU6581101A (en) * 2000-05-23 2001-12-03 Dyomics Gmbh Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds
DE10038237A1 (de) * 2000-08-04 2002-02-14 Aventis Res & Tech Gmbh & Co Verfahren zum Nachweis von Mutationen in Nucleotidsequenzen
CN1622830A (zh) * 2001-07-10 2005-06-01 安盛药业有限公司 肽基化合物
EP1281767A3 (en) * 2001-07-31 2003-05-28 Aladar A. Szalay Light emitting microorganisms and cells for diagnosis and therapy of tumors
RU2297409C2 (ru) * 2001-09-14 2007-04-20 Эмджен Инк. Диарильные соединения с мостиковой связью
JP2003261464A (ja) * 2002-03-07 2003-09-16 Fuji Photo Film Co Ltd 近赤外蛍光造影剤および蛍光造影法
DE10258150A1 (de) * 2002-12-10 2004-07-08 Dyomics Gmbh Hydrophile Marker auf der Basis von Benzopyrylo-Polymethinen
ES2557286T3 (es) * 2003-03-03 2016-01-25 Dyax Corp. Usos de péptidos que se unen específicamente al receptor del HGF (cMet)
GB0327494D0 (en) * 2003-11-26 2003-12-31 Amersham Plc Novel imaging agents
RU2393167C2 (ru) * 2004-06-16 2010-06-27 Джи-И Хелткер АС Пептидные соединения
WO2006036071A2 (en) * 2004-09-29 2006-04-06 Ge Healthcare As Urokinase plasminogen activator receptor targeted contrast agent
EP1674478A1 (en) * 2004-12-22 2006-06-28 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Fusion proteins and method for determining protein-protein-interactions in living cells and cell lysates, nucleic acids encoding these fusion proteins, as well as vectors and kits containing these
JP5400297B2 (ja) * 2005-12-27 2014-01-29 古河電気工業株式会社 蛍光ナノシリカ粒子、ナノ蛍光材料、それを用いたバイオチップ及びそのアッセイ法
WO2007139815A2 (en) * 2006-05-23 2007-12-06 Purdue Research Foundation Imaging and therapeutic method using progenitor cells
GB0615211D0 (en) * 2006-07-31 2006-09-06 Ge Healthcare Uk Ltd Asymmetric flouro-substituted polymethine dyes
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents

Also Published As

Publication number Publication date
RU2484111C9 (ru) 2013-09-20
MX2010001247A (es) 2010-03-01
EP2190931A2 (en) 2010-06-02
GB0718957D0 (en) 2007-11-07
CN101952369A (zh) 2011-01-19
RU2484111C2 (ru) 2013-06-10
JP2010534712A (ja) 2010-11-11
CA2694102A1 (en) 2009-02-05
RU2010101931A (ru) 2011-09-10
AU2008281818A1 (en) 2009-02-05
US20100196282A1 (en) 2010-08-05
WO2009016181A2 (en) 2009-02-05
WO2009016181A3 (en) 2010-02-25
KR20100051640A (ko) 2010-05-17

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Legal Events

Date Code Title Description
B15I Others concerning applications: loss of priority
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C09B 23/02 (2006.01), C09B 23/06 (2006.01), C09B 2