BRPI0817312A2 - Polinucleotídeos e polipeptídeos de fago fimru e usos dos mesmo - Google Patents

Polinucleotídeos e polipeptídeos de fago fimru e usos dos mesmo

Info

Publication number: BRPI0817312A2
Authority: BR; Brazil
Prior art keywords: phageru; polynucleotides; polypeptides; phageru polynucleotides
Prior art date: 2007-09-25

Application number

Other languages

English (en)

Inventor

Eric Heinz Altermann

Graeme Trevor Attwood

Sinead Leahy

Robert Starr Ronimus

Dong Li

Zhanhao Kong

Linley Rose Schofield

Debjit Dey

Catherine Mary Tootill

Carrie Sang

Christina Diana Moon

Petrus Hendricus Janssen

Original Assignee

Pastoral Greenhouse Gas Res Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-09-25

Filing date

2008-09-25

Publication date

2015-03-17

2008-09-25 Application filed by Pastoral Greenhouse Gas Res Ltd filed Critical Pastoral Greenhouse Gas Res Ltd

2015-03-17 Publication of BRPI0817312A2 publication Critical patent/BRPI0817312A2/pt

2018-05-29 Publication of BRPI0817312B1 publication Critical patent/BRPI0817312B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/641—Cysteine endopeptidases (3.4.22)
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/10—Detection of antigens from microorganism in sample from host
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/20—Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
- Y02P60/22—Methane [CH4], e.g. from rice paddies

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Virology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Hematology (AREA)
Analytical Chemistry (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)

BRPI0817312-5A 2007-09-25 2008-09-25 Métodos de inibição de uma célula metanógena, e composição farmacêutica BRPI0817312B1 (pt)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US97510407P	2007-09-25	2007-09-25
US60/975,104		2007-09-25
US98984107P	2007-11-22	2007-11-22
US98984007P	2007-11-22	2007-11-22
US60/989,841		2007-11-22
US60/989,840		2007-11-22
PCT/NZ2008/000248 WO2009041831A1 (en)	2007-09-25	2008-09-25	PHAGE ϕ-MRU POLYNUCLEOTIDES AND POLYPEPTIDES AND USES THEREOF

Publications (2)

Publication Number	Publication Date
BRPI0817312A2 true BRPI0817312A2 (pt)	2015-03-17
BRPI0817312B1 BRPI0817312B1 (pt)	2018-05-29

Family

ID=40511642

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
BRPI0817312-5A BRPI0817312B1 (pt)	2007-09-25	2008-09-25	Métodos de inibição de uma célula metanógena, e composição farmacêutica
BR122021010729-7A BR122021010729B1 (pt)	2007-09-25	2008-09-25	Composição de vacina
BRPI0817299A BRPI0817299A8 (pt)	2007-09-25	2008-09-25	vacinas e componentes de vacina para inibição de células microbianas
BR122020023381-8A BR122020023381B1 (pt)	2007-09-25	2008-09-25	Composição de vacina e kit para reduzir o crescimento de metanogênio ou a produção de metano em um ruminante
BR122021010737-8A BR122021010737B1 (pt)	2007-09-25	2008-09-25	Composição de vacina

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
BR122021010729-7A BR122021010729B1 (pt)	2007-09-25	2008-09-25	Composição de vacina
BRPI0817299A BRPI0817299A8 (pt)	2007-09-25	2008-09-25	vacinas e componentes de vacina para inibição de células microbianas
BR122020023381-8A BR122020023381B1 (pt)	2007-09-25	2008-09-25	Composição de vacina e kit para reduzir o crescimento de metanogênio ou a produção de metano em um ruminante
BR122021010737-8A BR122021010737B1 (pt)	2007-09-25	2008-09-25	Composição de vacina

Country Status (17)

Country	Link
US (7)	US8592556B2 (pt)
EP (5)	EP2203470A4 (pt)
JP (5)	JP5558356B2 (pt)
CN (4)	CN101918431B (pt)
AR (3)	AR068552A1 (pt)
AU (4)	AU2008304018A1 (pt)
BR (5)	BRPI0817312B1 (pt)
CA (3)	CA2700164C (pt)
CL (3)	CL2008002861A1 (pt)
DK (3)	DK2203467T3 (pt)
ES (3)	ES2625144T3 (pt)
MX (3)	MX2010003321A (pt)
NZ (1)	NZ745324A (pt)
RU (1)	RU2528854C2 (pt)
UY (3)	UY31361A1 (pt)
WO (3)	WO2009041832A2 (pt)
ZA (1)	ZA201001933B (pt)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2009041832A2 (en) *	2007-09-25	2009-04-02	Pastoral Greenhouse Gas Research Ltd	Vaccines and vaccine components for inhibition of microbial cells
GB0815484D0 (en)	2008-08-26	2008-10-01	Univ Leuven Kath	Antibacterial agents
KR101701890B1 (ko) *	2009-06-26	2017-02-02	뤼산도 아게	항균제
DK2445515T3 (en)	2009-06-26	2016-07-04	Univ Leuven Kath	antimicrobial agents
NZ750559A (en) *	2009-08-27	2023-01-27	Pastoral Greenhouse Gas Res Ltd	Complete genome sequence of the methanogen methanobrevibacter ruminantium
US9534223B2 (en) *	2010-04-27	2017-01-03	Lysando Ag	Method of reducing biofilms
TWI655204B (zh) *	2012-09-19	2019-04-01	韓商傑姆維克斯＆凱爾有限公司	穿膜胜肽以及包含該胜肽之共軛物及組成物(三)
CN114634950A (zh) *	2012-12-12	2022-06-17	布罗德研究所有限公司	用于序列操纵的crispr-cas组分系统、方法以及组合物
US10760064B2 (en)	2013-03-15	2020-09-01	The General Hospital Corporation	RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
WO2014204578A1 (en)	2013-06-21	2014-12-24	The General Hospital Corporation	Using rna-guided foki nucleases (rfns) to increase specificity for rna-guided genome editing
US10378027B2 (en)	2013-03-15	2019-08-13	The General Hospital Corporation	RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
CN106459995B (zh)	2013-11-07	2020-02-21	爱迪塔斯医药有限公司	使用统治型gRNA的CRISPR相关方法和组合物
JP6823593B2 (ja) *	2014-11-06	2021-02-03	イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．ＤｕＰｏｎｔＤｅＮｅｍｏｕｒｓＡｎｄＣｏｍｐａｎｙ	Ｒｎａ誘導型エンドヌクレアーゼの細胞へのペプチド媒介輸送
CN104789675A (zh) *	2015-04-15	2015-07-22	江苏师范大学	一种检测荷斯坦奶牛瘤胃微生物的方法
CN108026566A (zh) *	2015-05-04	2018-05-11	特拉维夫大学拉莫特有限公司	用于使dna片段化的方法和试剂盒
US9512446B1 (en)	2015-08-28	2016-12-06	The General Hospital Corporation	Engineered CRISPR-Cas9 nucleases
US9926546B2 (en)	2015-08-28	2018-03-27	The General Hospital Corporation	Engineered CRISPR-Cas9 nucleases
DK3484996T3 (da) *	2016-07-14	2020-12-07	Basf Se	Fermenteringsmedium, der omfatter et chelateringsmiddel
CA3048863A1 (en) *	2016-12-29	2018-07-05	Illumina, Inc.	Analysis system for orthogonal access to and tagging of biomolecules in cellular compartments
CN112986589B (zh)	2017-01-05	2023-01-24	深圳迈瑞生物医疗电子股份有限公司	网织红细胞模拟粒子、血小板模拟粒子制备方法及质控物
US10745439B2 (en) *	2017-03-20	2020-08-18	Regents Of The University Of Minnesota	Kinase substrates and methods of use thereof
WO2019147743A1 (en)	2018-01-26	2019-08-01	Massachusetts Institute Of Technology	Structure-guided chemical modification of guide rna and its applications
KR20240038811A (ko) *	2018-03-19	2024-03-25	리제너론 파마슈티칼스 인코포레이티드	CRISPR/Cas 시스템을 사용한 동물에서의 전사 조절
EP3880698A4 (en)	2018-11-14	2022-11-30	RubrYc Therapeutics, Inc.	MANIPULATED CD25 POLYPEPTIDES AND USES THEREOF
CN113677359A (zh)	2018-11-14	2021-11-19	鲁比克治疗股份有限公司	Cd25抗体
CN109627301B (zh) *	2019-02-18	2022-08-05	浙江新银象生物工程有限公司	Nisin固体稳定剂开发及应用
JP2023518377A (ja) *	2020-03-19	2023-05-01	マイクレオスヒューマンヘルスビー．ブイ．	安定化された対象となるタンパク質
US20230072496A1 (en) *	2020-04-10	2023-03-09	Liberty Biosecurity, Llc	Polypeptide compositions and uses thereof
CN112143747B (zh) *	2020-09-09	2022-09-13	昆明理工大学	一种噬菌体裂解酶及其基因、基因重组表达载体与应用
PT4037666T (pt)	2020-12-08	2024-06-25	Ruminant Biotech Corp Ltd	Aperfeiçoamentos de dispositivos e métodos para administração de substâncias a animais
CN112961217B (zh) *	2021-03-19	2022-11-08	江苏元本生物科技有限公司	一种靶向Siglec-15的噬菌体多肽
CN113121705B (zh) *	2021-04-19	2023-03-24	成都英普博集生物科技有限公司	用于制备短肽混合物的融合蛋白、目的多肽、短肽混合物的制备方法及应用
CA3261760A1 (en) *	2022-07-11	2024-01-18	Arkea Bio Corp.	COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS
CN115417927A (zh) *	2022-09-08	2022-12-02	南京松天盛科生物科技有限公司	小鼠腹水致敏物及其应用
CN120225671A (zh) *	2022-11-03	2025-06-27	螺旋纳米技术公司	瘤胃和产甲烷菌疫苗及其用途
CN115938486B (zh) *	2022-12-06	2023-11-10	内蒙古农业大学	基于图神经网络的抗菌性乳酸菌株筛选方法
WO2025207521A1 (en) *	2024-03-25	2025-10-02	Silage Labs, Inc.	Bacteria expressing lysins for inhibition of methanogenesis
WO2025219570A1 (en)	2024-04-17	2025-10-23	Johannes Kepler Universität Linz	Composition for inhibiting protein translocation and methods using the same
WO2025233675A1 (en) *	2024-05-10	2025-11-13	Institut Pasteur	Use of talosaminidase to regulate populations of archaeal methanogens in industrial, agricultural and medical settings
CN120249257B (zh) *	2025-05-08	2026-05-05	浙江大学	与PeiR裂解酶具有相同蛋白家族注释的产甲烷菌裂解酶及其应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US159861A (en) *		1875-02-16		Improvement in brooms
NZ207394A (en)	1983-03-08	1987-03-06	Commw Serum Lab Commission	Detecting or determining sequence of amino acids
ZA843277B (en) *	1983-05-03	1984-12-24	Ssm Int Chem Co Ltd	A composition of improved pharmaceutical activity and utilization thereof for veterinary use
GB8815968D0 (en) *	1988-07-05	1988-08-10	Pfizer Ltd	Veterinary devices
JPH05219927A (ja) *	1992-02-14	1993-08-31	Gumma Pref Gov	飼料の混合装置及び混合飼料の製造方法
JP3651915B2 (ja) *	1993-06-30	2005-05-25	財団法人神奈川科学技術アカデミー	シグナル配列ペプチドをコードするｄｎａ断片の探索法及びそのためのベクター
ATE262349T1 (de) *	1993-10-19	2004-04-15	Commw Scient Ind Res Org	Methode zur verbesserung der nahrungsverwertung von wiederkäuern oder wiederkäuer-ähnlichen tieren
DE69433180T2 (de)	1993-10-26	2004-06-24	Affymetrix, Inc., Santa Clara	Felder von nukleinsaeuresonden auf biologischen chips
BR9506533A (pt)	1994-01-20	1997-09-16	Pastoral Agric Res Inst Nz Ltd	Dispositivo para administração de materiais benéficos a ruminantes
NZ278977A (en)	1994-01-20	1997-03-24	Pastoral Agric Res Inst Nz Ltd	Sustained release bolus for ruminants
US6015880A (en)	1994-03-16	2000-01-18	California Institute Of Technology	Method and substrate for performing multiple sequential reactions on a matrix
AUPN353695A0 (en)	1995-06-14	1995-07-06	Commonwealth Scientific And Industrial Research Organisation	Immunogenic preparation and method for improving the productivity of ruminant animals
WO1998007830A2 (en) *	1996-08-22	1998-02-26	The Institute For Genomic Research	COMPLETE GENOME SEQUENCE OF THE METHANOGENIC ARCHAEON, $i(METHANOCOCCUS JANNASCHII)
US5985907A (en) *	1998-08-12	1999-11-16	Health Research, Inc.	Method for inhibiting growth of methanogens
AU2002306849A1 (en) *	2001-03-21	2002-10-08	Elitra Pharmaceuticals, Inc.	Identification of essential genes in microorganisms
AU2002326949A1 (en)	2001-09-18	2003-05-12	The Board Of Regents Of The University Of Nebraska	Method for the inhibition of methanogenesis
US7314974B2 (en) *	2002-02-21	2008-01-01	Monsanto Technology, Llc	Expression of microbial proteins in plants for production of plants with improved properties
WO2003076575A2 (en) *	2002-03-04	2003-09-18	Fidelity Systems, Inc., Et Al.	The complete genome and protein sequence of the hyperthermophile methanopyrus kandleri av19 and monophyly of archael methanogens and methods of use thereof
SE523209C2 (sv) *	2002-05-14	2004-04-06	Akzo Nobel Nv	Förfarande för att reducera metanbildningen från matspjälkningsaktiviteter hos djur
EP1861490A4 (en)	2005-03-23	2010-11-17	Univ St Louis	USE OF ARCHAEA FOR MODULATING NUTRITIONAL FUNCTIONALITY OF GASTROINTESTINAL BIOZOOSIS
WO2009041832A2 (en) *	2007-09-25	2009-04-02	Pastoral Greenhouse Gas Research Ltd	Vaccines and vaccine components for inhibition of microbial cells
CN101434924A (zh) *	2008-12-17	2009-05-20	中南大学	一种分离严格厌氧产甲烷古菌的方法
NZ750559A (en) *	2009-08-27	2023-01-27	Pastoral Greenhouse Gas Res Ltd	Complete genome sequence of the methanogen methanobrevibacter ruminantium
CN101864362B (zh) *	2010-05-19	2012-05-09	江苏加德绿色能源有限公司	一种复合微生物菌剂及其应用
DE102011119230B4 (de) *	2011-11-23	2013-07-11	Audi Ag	Kraftwagen-Blinkleuchte und Verfahren zum Betreiben einer Blinkleuchte
EP2935364A2 (en) *	2012-12-21	2015-10-28	Danisco US Inc.	Production of isoprene, isoprenoid, and isoprenoid precursors using an alternative lower mevalonate pathway

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DK2203466T3 (en)	2016-07-25
CA2700129C (en)	2021-07-20
EP2203466B1 (en)	2016-04-06
ZA201001933B (en)	2013-10-30
NZ745324A (en)	2023-02-24
CA2700164A1 (en)	2009-04-02
CN101932595B (zh)	2016-02-10
ES2625144T3 (es)	2017-07-18
WO2009041831A1 (en)	2009-04-02
AU2008305846A1 (en)	2009-04-02
US10590170B2 (en)	2020-03-17
JP2017046704A (ja)	2017-03-09
CA2700164C (en)	2018-05-29
RU2528854C2 (ru)	2014-09-20
UY31359A1 (es)	2009-04-30
EP2203467A1 (en)	2010-07-07
EP2203466A4 (en)	2011-04-13
CL2008002860A1 (es)	2009-06-05
AU2014210649B2 (en)	2016-09-08
JP2010539926A (ja)	2010-12-24
CN101918431B (zh)	2014-10-08
WO2009041830A2 (en)	2009-04-02
EP3936516A1 (en)	2022-01-12
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CL2008002859A1 (es)	2009-03-06
CN102015755A (zh)	2011-04-13
AU2008304018A1 (en)	2009-04-02
US20140220636A1 (en)	2014-08-07
AR068552A1 (es)	2009-11-18
AR068553A1 (es)	2009-11-18
BRPI0817312B1 (pt)	2018-05-29
AR068551A1 (es)	2009-11-18
EP2203470A4 (en)	2011-04-13
CN101932595A (zh)	2010-12-29
US8586709B2 (en)	2013-11-19
UY31360A1 (es)	2009-04-30
CN107129524B (zh)	2023-11-21
JP2010539928A (ja)	2010-12-24
WO2009041832A9 (en)	2009-10-22
US20210332087A1 (en)	2021-10-28
US20100209999A1 (en)	2010-08-19
AU2014210649A1 (en)	2014-09-04
NZ780936A (en)	2024-08-30
CA2700162C (en)	2018-08-14
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DK2203467T3 (en)	2017-03-27
US20170342112A1 (en)	2017-11-30
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US8592556B2 (en)	2013-11-26
EP2203466A2 (en)	2010-07-07
US10995120B2 (en)	2021-05-04
US20100221185A1 (en)	2010-09-02
EP3327030A1 (en)	2018-05-30
BRPI0817299A8 (pt)	2019-01-29
WO2009041832A2 (en)	2009-04-02
JP6067209B2 (ja)	2017-01-25
MX2010003321A (es)	2010-08-03
CN101918431A (zh)	2010-12-15
CN107129524A (zh)	2017-09-05
DK3327030T3 (da)	2021-10-04
AU2008304019A1 (en)	2009-04-02
US9296789B2 (en)	2016-03-29
BR122020023381B1 (pt)	2021-09-08
JP2010539927A (ja)	2010-12-24
MX2010003319A (es)	2010-09-10
UY31361A1 (es)	2009-04-30
US20100209998A1 (en)	2010-08-19
EP3327030B1 (en)	2021-07-21
EP2203470A2 (en)	2010-07-07
WO2009041831A9 (en)	2009-11-05
WO2009041832A3 (en)	2009-06-11
US20200325180A1 (en)	2020-10-15
CL2008002861A1 (es)	2009-03-06
BR122021010737B1 (pt)	2021-09-21
BR122021010729B1 (pt)	2022-02-15
CA2700129A1 (en)	2009-04-02
WO2009041830A9 (en)	2009-08-27
ES2587595T3 (es)	2016-10-25
EP2203467B1 (en)	2016-12-14
JP2015042166A (ja)	2015-03-05
MX2010003328A (es)	2010-08-16
MX340736B (es)	2016-07-22
JP5558356B2 (ja)	2014-07-23
CA2700162A1 (en)	2009-04-02
BRPI0817299A2 (pt)	2015-06-16

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