BRPI0818457A2 - Derivados de oxadiazol - Google Patents

Derivados de oxadiazol

Info

Publication number: BRPI0818457A2
Authority: BR; Brazil
Prior art keywords: oxadiazol derivatives; oxadiazol; derivatives
Prior art date: 2007-10-04

Application number

Other languages

English (en)

Inventor

Anna Quattropani

Wolfgang Sauer

Mathilde Muzerelle

Delphine Marin

Cyril Montagne

Stefano Crosignani

Agnes Bombrun

Jérôme Dorbais

Jérôme Gonzalez

Patrick Gerber

Original Assignee

Merck Serono Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-04

Filing date

2008-10-01

Publication date

2015-04-14

2008-10-01 Application filed by Merck Serono Sa filed Critical Merck Serono Sa

2015-04-14 Publication of BRPI0818457A2 publication Critical patent/BRPI0818457A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Oncology (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Neurology (AREA)
Communicable Diseases (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Gastroenterology & Hepatology (AREA)
Cardiology (AREA)
Transplantation (AREA)
Tropical Medicine & Parasitology (AREA)
Biotechnology (AREA)

BRPI0818457 2007-10-04 2008-10-01 Derivados de oxadiazol BRPI0818457A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP07117921		2007-10-04
US99825407P	2007-10-09	2007-10-09
PCT/EP2008/063180 WO2009043889A2 (en)	2007-10-04	2008-10-01	Oxadiazole derivatives

Publications (1)

Publication Number	Publication Date
BRPI0818457A2 true BRPI0818457A2 (pt)	2015-04-14

Family

ID=38984441

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0818457 BRPI0818457A2 (pt)	2007-10-04	2008-10-01	Derivados de oxadiazol

Country Status (15)

Country	Link
US (1)	US8202865B2 (pt)
EP (1)	EP2193125B1 (pt)
JP (2)	JP6144450B2 (pt)
KR (1)	KR20100075608A (pt)
CN (1)	CN101970420B (pt)
AR (1)	AR068731A1 (pt)
AU (1)	AU2008306885B2 (pt)
BR (1)	BRPI0818457A2 (pt)
CA (1)	CA2696863C (pt)
EA (1)	EA201070422A1 (pt)
ES (1)	ES2622423T3 (pt)
IL (1)	IL204521A0 (pt)
MX (1)	MX2010003612A (pt)
WO (1)	WO2009043889A2 (pt)
ZA (2)	ZA201001121B (pt)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
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EP4101846B1 (en)	2003-04-11	2023-08-02	PTC Therapeutics, Inc.	1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease
DK2125797T3 (da)	2007-03-16	2014-02-10	Actelion Pharmaceuticals Ltd	Aminopyridinderivater som s1p1/edg1-receptoragonister
US8404676B2 (en) *	2007-10-04	2013-03-26	Merck Serono Sa	Oxadiazole diaryl compounds
EP2250165B1 (en) *	2007-12-21	2018-07-25	Merck Serono S.A.	Triazole oxadiazoles derivatives
MX2010009645A (es)	2008-03-07	2010-09-28	Actelion Pharmaceuticals Ltd	Derivados novedosos de aminometil benceno.
ES2405054T3 (es)	2009-01-23	2013-05-30	Bristol-Myers Squibb Company	Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato
WO2010085581A1 (en)	2009-01-23	2010-07-29	Bristol-Myers Squibb Company	Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
EP2389377B1 (en)	2009-01-23	2014-07-16	Bristol-Myers Squibb Company	Substituted oxadiazole derivatives as s1p agonists in the treatment of autoimmune and inflammatory diseases
EP2241558A1 (en) *	2009-04-03	2010-10-20	Merck Serono SA	Oxadiazole derivatives
TW201107302A (en) *	2009-06-26	2011-03-01	Glaxo Group Ltd	Compounds
GB0911130D0 (en) *	2009-06-26	2009-08-12	Glaxo Group Ltd	Novel compounds
TWI410421B (zh)	2009-07-16	2013-10-01	Actelion Pharmaceuticals Ltd	吡啶－４－基衍生物
US8399451B2 (en)	2009-08-07	2013-03-19	Bristol-Myers Squibb Company	Heterocyclic compounds
AU2010319879A1 (en)	2009-10-29	2012-06-14	Bristol-Myers Squibb Company	Tricyclic heterocyclic compounds
WO2011054530A1 (en)	2009-11-05	2011-05-12	Fibrostatin, S.L.	Gpbp inhibition using q2 peptidomimetics
US20130012491A1 (en) *	2010-03-17	2013-01-10	Glaxo Group Limited	Pyrimidine derivatives for use as sphingosine 1-phosphate 1 (s1p1) receptor agonists
JP5735634B2 (ja)	2010-04-23	2015-06-17	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	スフィンゴシン−１−リン酸受容体１アゴニストとしての４−（５−イソオキサゾリルまたは５−ピラゾリル−１，２，４−オキサジアゾール−３−イル）−マンデル酸アミド化合物
TW201206429A (en) *	2010-07-08	2012-02-16	Merck Serono Sa	Substituted oxadiazole derivatives
JP5788507B2 (ja)	2010-07-20	2015-09-30	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	置換３−フェニル−１，２，４−オキサジアゾール化合物
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JP2013544811A (ja)	2010-11-03	2013-12-19	ブリストル−マイヤーズスクイブカンパニー	自己免疫疾患および血管疾患の治療用のｓ１ｐ１アゴニストとしての複素環式化合物
RU2013127636A (ru)	2010-11-22	2014-12-27	Аллерган, Инк.	Новые соединения в качестве модуляторов рецепторов с терапевтической полезностью
CA2818470C (en)	2011-01-19	2019-03-05	Actelion Pharmaceuticals Ltd	2-methoxy-pyridin-4-yl derivatives
EP2511275A1 (en) *	2011-04-12	2012-10-17	Bioprojet	Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists
CN102250035A (zh) *	2011-06-10	2011-11-23	北京富卡生物技术有限公司	二芳基取代-1，3，4-噁二唑化合物的合成方法和其药物用途
TWI613182B (zh)	2013-02-21	2018-02-01	必治妥美雅史谷比公司	雙環化合物
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CA2696863C (en)	2016-10-18
EP2193125B1 (en)	2017-01-11
MX2010003612A (es)	2010-04-30
EP2193125A2 (en)	2010-06-09
JP6144450B2 (ja)	2017-06-07
CN101970420A (zh)	2011-02-09
CN101970420B (zh)	2014-09-24
ZA201104423B (en)	2012-03-28
JP2010540592A (ja)	2010-12-24
JP6148263B2 (ja)	2017-06-14
ES2622423T3 (es)	2017-07-06
AR068731A1 (es)	2009-12-02
US20100240658A1 (en)	2010-09-23
WO2009043889A3 (en)	2009-08-20
AU2008306885B2 (en)	2013-12-05
WO2009043889A2 (en)	2009-04-09
JP2015063571A (ja)	2015-04-09
KR20100075608A (ko)	2010-07-02
IL204521A0 (en)	2010-11-30
US8202865B2 (en)	2012-06-19
AU2008306885A1 (en)	2009-04-09
CA2696863A1 (en)	2009-04-09
EA201070422A1 (ru)	2010-12-30
ZA201001121B (en)	2011-10-26

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