BRPI0812064A2 - Formulação farmacêutica, tabletes, e, processo para a produção de uma formulação farmacêutica - Google Patents
Formulação farmacêutica, tabletes, e, processo para a produção de uma formulação farmacêuticaInfo
- Publication number
- BRPI0812064A2 BRPI0812064A2 BRPI0812064-1A2A BRPI0812064A BRPI0812064A2 BR PI0812064 A2 BRPI0812064 A2 BR PI0812064A2 BR PI0812064 A BRPI0812064 A BR PI0812064A BR PI0812064 A2 BRPI0812064 A2 BR PI0812064A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical formulation
- tables
- production
- formulation
- pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07109722 | 2007-06-06 | ||
| PCT/EP2008/056805 WO2008148742A2 (de) | 2007-06-06 | 2008-06-03 | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0812064A2 true BRPI0812064A2 (pt) | 2014-11-25 |
| BRPI0812064B1 BRPI0812064B1 (pt) | 2019-08-13 |
| BRPI0812064B8 BRPI0812064B8 (pt) | 2021-05-25 |
Family
ID=39643971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812064A BRPI0812064B8 (pt) | 2007-06-06 | 2008-06-03 | formulação farmacêutica na forma de aglomerados, comprimidos, e, processo para a produção de uma formulação farmacêutica |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10406105B2 (pt) |
| EP (1) | EP2164462B1 (pt) |
| JP (2) | JP5627455B2 (pt) |
| KR (2) | KR101903781B1 (pt) |
| CN (1) | CN101707930B (pt) |
| AU (1) | AU2008258627A1 (pt) |
| BR (1) | BRPI0812064B8 (pt) |
| CA (1) | CA2686964A1 (pt) |
| ES (1) | ES2639130T3 (pt) |
| MX (1) | MX2009013063A (pt) |
| WO (1) | WO2008148742A2 (pt) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| AUPS088702A0 (en) * | 2002-03-04 | 2002-03-28 | Borody, Thomas Julius | Electrolyte purgative |
| UA95093C2 (uk) | 2005-12-07 | 2011-07-11 | Нікомед Фарма Ас | Спосіб одержання кальцієвмісної сполуки |
| MX2009013063A (es) | 2007-06-06 | 2010-01-15 | Basf Se | Formulacion farmaceutica para la produccion de tabletas de desintegracion rapida. |
| EP2164460B1 (de) | 2007-06-06 | 2017-08-09 | Basf Se | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
| CN102988318A (zh) * | 2008-11-25 | 2013-03-27 | 田边三菱制药株式会社 | 口腔速崩片及其制备方法 |
| TW201028168A (en) * | 2008-12-19 | 2010-08-01 | Solvay Pharm Bv | Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability |
| TWI455733B (zh) * | 2009-03-30 | 2014-10-11 | Toray Industries | 口腔內崩壞性被覆錠劑 |
| WO2010119851A1 (ja) * | 2009-04-14 | 2010-10-21 | ライオン株式会社 | 口腔内崩壊錠 |
| JP6073543B2 (ja) * | 2010-07-08 | 2017-02-01 | 沢井製薬株式会社 | ロラタジン含有口腔内崩壊錠の製造方法 |
| EP3424515A3 (en) | 2010-08-04 | 2019-06-19 | Thomas Julius Borody | Stool collection devices and methods for using them |
| AU2011342368B2 (en) | 2010-12-13 | 2016-11-17 | Rite-Prep Pty Ltd | Gastric and colonic formulations and methods for making and using them |
| CN107252419A (zh) * | 2010-12-22 | 2017-10-17 | 巴斯夫欧洲公司 | 快速崩解的固体包衣剂型 |
| US8715729B2 (en) | 2010-12-22 | 2014-05-06 | Basf Se | Rapidly disintegrating, solid coated dosage form |
| US9968638B2 (en) | 2011-03-09 | 2018-05-15 | Regents Of The University Of Minnesota | Compositions and methods for transplantation of colon microbiota |
| JP6245786B2 (ja) * | 2011-10-17 | 2017-12-13 | 大同化成工業株式会社 | 医薬用結合剤及び該結合剤を用いた製剤 |
| IN2014DN07797A (pt) | 2012-03-29 | 2015-05-15 | Daicel Corp | |
| US9719144B2 (en) | 2012-05-25 | 2017-08-01 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| WO2013181694A1 (en) | 2012-06-04 | 2013-12-12 | Gaurav Agrawal | Compositions and methods for treating crohn's disease and related conditions and infections |
| PT2877163T (pt) | 2012-07-27 | 2019-05-24 | Redhill Biopharma Ltd | Formulações e métodos de fabrico de formulações para utilização na evacuação colónica |
| JP6230539B2 (ja) | 2012-09-20 | 2017-11-15 | 株式会社ダイセル | 酸型カルボキシメチルセルロース及び結晶セルロースを含む崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 |
| ITMI20121628A1 (it) * | 2012-09-28 | 2014-03-29 | Pharmafilm Srl | Film orodisperdibili autosupportanti a rapida dissoluzione per uso terapeutico o alimentare |
| WO2014176632A1 (en) | 2013-04-30 | 2014-11-06 | Borody Thomas J | Compositions and methods for treating microbiota-related psychotropic conditions and diseases |
| WO2015046223A1 (ja) * | 2013-09-27 | 2015-04-02 | 株式会社ダイセル | 二段階の湿式造粒工程で製造される崩壊性粒子組成物及び該組成物を含む口腔内崩壊錠剤 |
| EP3135300B1 (en) | 2014-04-21 | 2022-03-30 | Daicel Corporation | Disintegrating particle composition including microfibrous cellulose |
| EP3206671B1 (en) * | 2014-10-16 | 2024-06-12 | Cargill, Incorporated | Process for preparing a directly compressible erythritol and uses thereof |
| BR112017024264B1 (pt) | 2015-05-14 | 2022-07-12 | Crestovo Holdings Llc | Composições para transplante de flora fecal e métodos de preparação e utilização das mesmas, e dispositivos para sua administração |
| KR102534545B1 (ko) | 2015-05-22 | 2023-05-18 | 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 | 자폐 스펙트럼 장애 및 관련된 증상을 치료하는 방법 |
| US11214773B2 (en) | 2015-09-24 | 2022-01-04 | San Diego State University (Sdsu) Foundation | Antibacterial and protective bacteriophage formulations and methods for making and using them |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| WO2018071537A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| WO2018071536A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating primary sclerosing cholangitis and related disorders |
| US11040073B2 (en) | 2017-04-05 | 2021-06-22 | Finch Therapeutics Holdings Llc | Compositions and methods for treating diverticulitis and related disorders |
| EP3606541A1 (en) | 2017-04-05 | 2020-02-12 | Crestovo Holdings LLC | Compositions and methods for treating parkinson's disease (pd) and related disorders |
| JP2020521760A (ja) | 2017-05-26 | 2020-07-27 | クレストヴォ・ホールディングス・エルエルシー | 糞便微生物ベースの治療剤を含む凍結乾燥組成物ならびにそれを製造および使用する方法 |
| JP2020530494A (ja) | 2017-08-07 | 2020-10-22 | フィンチ セラピューティクス、インコーポレイテッド. | 健康な腸バリアを維持及び回復するための組成物及び方法 |
| US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
| EP3856212A1 (en) | 2018-09-27 | 2021-08-04 | Finch Therapeutics Holdings LLC | Compositions and methods for treating epilepsy and related disorders |
| WO2020211915A1 (en) * | 2019-04-17 | 2020-10-22 | Nordiccan A/S | Fast disintegrating cannabinoid tablets |
| US11633351B2 (en) * | 2019-12-13 | 2023-04-25 | Nordiccan A/S | Fast disintegrating cannabinoid tablets |
| PH12021553137A1 (en) | 2019-07-19 | 2022-07-25 | Finch Therapeutics Holdings Llc | Methods and products for treatment of gastrointestinal disorders |
| US11179331B1 (en) * | 2020-04-21 | 2021-11-23 | Cure Pharmaceutcai Holding Corp | Oral soluble film containing sildenafil citrate |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3434138A1 (de) | 1984-09-18 | 1986-03-27 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von unloeslichen, nur wenig quellbaren pulverfoermigen polymerisaten |
| US5569469A (en) | 1984-10-16 | 1996-10-29 | Vectorpharma International, S.P.A. | Poorly soluble medicaments supported on polymer substances in a form suitable for increasing their dissolving rate |
| GB8518301D0 (en) | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| CA2159419C (en) | 1994-10-17 | 2006-07-04 | Pieter De Haan | Solid pharmaceutical composition comprising an excipient capable of binding water |
| US5879342A (en) | 1996-10-21 | 1999-03-09 | Kelley; Gregory S. | Flexible and reinforced tubing |
| EP0839526A3 (en) | 1996-10-31 | 1999-01-07 | Takeda Chemical Industries, Ltd. | Solid pharmaceutical preparation with fast buccal disintegration or dissolution |
| JP2001504342A (ja) | 1996-11-15 | 2001-04-03 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 成形されたまたは未成形のポリオール材料の製造方法 |
| DE19709663A1 (de) * | 1997-03-10 | 1998-09-17 | Basf Ag | Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten als Bindemittel zur Herstellung von festen pharmazeutischen Darreichungsformen |
| US5874418A (en) | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
| FR2781152B1 (fr) | 1998-07-20 | 2001-07-06 | Permatec Tech Ag | Utilisation d'un polymere de type acrylique en tant qu'agent de desagregation |
| TW585786B (en) * | 1998-07-28 | 2004-05-01 | Takeda Chemical Industries Ltd | Lansoprazole-containing rapidly disintegrable solid pharmaceutical composition |
| DE19912031A1 (de) | 1999-03-17 | 2000-09-21 | Basf Ag | Verwendung von quervernetztem Polyvinylpyrrolidon zur Erhöhung der Zerfallgeschwindigkeit von kompakten teilchenförmigen Wasch- und Reinigungsmitteln |
| US20020071864A1 (en) * | 1999-03-25 | 2002-06-13 | Yuhan Corporation | Rapidly disintegrable tablet for oral administration |
| US6495177B1 (en) | 1999-08-13 | 2002-12-17 | Warner Chilcott Laboratories Ireland Limited | Orally dissolvable nutritional supplement |
| DE10011137A1 (de) | 2000-03-10 | 2001-09-13 | Basf Ag | Verfahren zur Einstellung der Teilchengröße von Popcornpolymeren während der Popcornpolymerisation |
| US20020147232A1 (en) * | 2000-05-26 | 2002-10-10 | Claus Sundgreen | Pharmaceutical compositions comprising desglymidodrine as an active drug substance |
| US7147869B2 (en) | 2000-12-07 | 2006-12-12 | Altana Pharma Ag | Rapidly disintegrating tablet comprising an acid-labile active ingredient |
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| US20020127277A1 (en) | 2000-12-22 | 2002-09-12 | Yihong Qiu | Solid dosage forms of divalproex sodium |
| EP1429736A2 (en) * | 2001-09-26 | 2004-06-23 | Pharmacia Corporation | Organoleptically acceptable intraorally disintegrating compositions |
| GB0124953D0 (en) | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
| FR2831820B1 (fr) * | 2001-11-05 | 2004-08-20 | Ethypharm Sa | Comprime orodispersible presentant une grande homogeneite et son procede de preparation |
| US6723348B2 (en) | 2001-11-16 | 2004-04-20 | Ethypharm | Orodispersible tablets containing fexofenadine |
| US7118765B2 (en) | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
| EP1455813B1 (en) | 2001-12-18 | 2015-07-15 | mondoBIOTECH AG | Interferon gamma in combination with a diagnostic array for use in the improved treatment of idiopathic pulmonary fibrosis |
| BRPI0307786B8 (pt) * | 2002-02-26 | 2021-05-25 | Astrazeneca Ab | composição farmacêutica, método para preparar a mesma, métodos para inibir a taxa de precipitação do agente da solução no trato gi, e para reduzir variabilidade inter-pacientes no que se refere à biodisponibilidade e/ou concentrações plásmáticas do agente, e, uso de um celulose éter solúvel em água ou de um éster de um celulose éter solúvel em água |
| GB0204771D0 (en) * | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
| JP2004026521A (ja) | 2002-06-21 | 2004-01-29 | Mitsubishi Chemicals Corp | フラーレンの製造設備及びフラーレンの製造方法 |
| JP2006508134A (ja) | 2002-11-08 | 2006-03-09 | グラクソ グループ リミテッド | 医薬組成物 |
| WO2004073687A1 (en) * | 2003-02-19 | 2004-09-02 | H. Lundbeck A/S | Method for preparation of an agglomerate using melt agglomeration |
| JP2004265216A (ja) | 2003-03-03 | 2004-09-24 | Seiko Epson Corp | 印刷装置、受信装置、中継装置、印刷システムおよび印刷方法 |
| US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
| US20050244343A1 (en) | 2004-04-30 | 2005-11-03 | Withiam Michael C | Oral care products comprising silica |
| US20050244492A1 (en) * | 2004-04-30 | 2005-11-03 | Mehra Dev K | Rapidly disintegrating tablets comprising titanium dioxide |
| JP2006076971A (ja) * | 2004-09-13 | 2006-03-23 | Basf Ag | 口腔内崩壊錠 |
| JP4446177B2 (ja) * | 2005-01-21 | 2010-04-07 | 東和薬品株式会社 | 耐湿性口腔内崩壊錠の製造方法 |
| ES2403167T3 (es) * | 2005-12-21 | 2013-05-14 | Basf Se | Polivinilpirrolidona entrelazada finamente dividida como agente desintegrador de tabletas |
| US8425935B2 (en) | 2005-12-21 | 2013-04-23 | Basf Se | Pharmaceutical formulation for producing rapidly disintegrating tablets |
| MX2009013063A (es) | 2007-06-06 | 2010-01-15 | Basf Se | Formulacion farmaceutica para la produccion de tabletas de desintegracion rapida. |
| CN102046147B (zh) | 2007-06-06 | 2013-03-20 | 巴斯夫欧洲公司 | 用于制备快速崩解的片剂的药物配制剂 |
| JP2010529073A (ja) | 2007-06-06 | 2010-08-26 | ビーエーエスエフ ソシエタス・ヨーロピア | チュアブル錠及びトローチ剤製造のための医薬製剤 |
| EP2164460B1 (de) | 2007-06-06 | 2017-08-09 | Basf Se | Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten |
| DE102008038678B4 (de) * | 2008-08-12 | 2012-03-08 | Continental Automotive Gmbh | Verfahren und Vorrichtung zum Schätzen einer Emission mindestens einer Abgaskomponente |
-
2008
- 2008-06-03 MX MX2009013063A patent/MX2009013063A/es not_active Application Discontinuation
- 2008-06-03 CN CN2008800188988A patent/CN101707930B/zh active Active
- 2008-06-03 BR BRPI0812064A patent/BRPI0812064B8/pt active IP Right Grant
- 2008-06-03 WO PCT/EP2008/056805 patent/WO2008148742A2/de not_active Ceased
- 2008-06-03 EP EP08760389.0A patent/EP2164462B1/de active Active
- 2008-06-03 KR KR1020107000103A patent/KR101903781B1/ko active Active
- 2008-06-03 AU AU2008258627A patent/AU2008258627A1/en not_active Abandoned
- 2008-06-03 ES ES08760389.0T patent/ES2639130T3/es active Active
- 2008-06-03 US US12/663,046 patent/US10406105B2/en active Active
- 2008-06-03 CA CA002686964A patent/CA2686964A1/en not_active Abandoned
- 2008-06-03 JP JP2010510759A patent/JP5627455B2/ja active Active
- 2008-06-03 KR KR1020167017268A patent/KR20160083132A/ko not_active Ceased
-
2014
- 2014-02-21 JP JP2014031168A patent/JP2014114322A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2014114322A (ja) | 2014-06-26 |
| KR101903781B1 (ko) | 2018-11-13 |
| EP2164462A2 (de) | 2010-03-24 |
| EP2164462B1 (de) | 2017-05-31 |
| BRPI0812064B1 (pt) | 2019-08-13 |
| KR20100028624A (ko) | 2010-03-12 |
| WO2008148742A2 (de) | 2008-12-11 |
| MX2009013063A (es) | 2010-01-15 |
| KR20160083132A (ko) | 2016-07-11 |
| JP2010529074A (ja) | 2010-08-26 |
| ES2639130T3 (es) | 2017-10-25 |
| AU2008258627A1 (en) | 2008-12-11 |
| BRPI0812064B8 (pt) | 2021-05-25 |
| CN101707930B (zh) | 2013-10-30 |
| WO2008148742A3 (de) | 2009-08-13 |
| JP5627455B2 (ja) | 2014-11-19 |
| CN101707930A (zh) | 2010-05-12 |
| CA2686964A1 (en) | 2008-12-11 |
| US10406105B2 (en) | 2019-09-10 |
| US20100178349A1 (en) | 2010-07-15 |
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