BRPI0821508A2 - Secreção de ácidos graxos por micro-organismos fotossintéticos - Google Patents
Secreção de ácidos graxos por micro-organismos fotossintéticosInfo
- Publication number
- BRPI0821508A2 BRPI0821508A2 BRPI0821508-1A2A BRPI0821508A BRPI0821508A2 BR PI0821508 A2 BRPI0821508 A2 BR PI0821508A2 BR PI0821508 A BRPI0821508 A BR PI0821508A BR PI0821508 A2 BRPI0821508 A2 BR PI0821508A2
- Authority
- BR
- Brazil
- Prior art keywords
- organisms
- section
- fatty acids
- photosynthetic micro
- photosynthetic
- Prior art date
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
- 230000000243 photosynthetic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/649—Biodiesel, i.e. fatty acid alkyl esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02T—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO TRANSPORTATION
- Y02T50/00—Aeronautics or air transport
- Y02T50/60—Efficient propulsion technologies, e.g. for aircraft
- Y02T50/678—Aviation using fuels of non-fossil origin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US733307P | 2007-12-11 | 2007-12-11 | |
| PCT/US2008/086485 WO2009076559A1 (en) | 2007-12-11 | 2008-12-11 | Secretion of fatty aicds by photosynthetic microorganisms |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0821508A2 true BRPI0821508A2 (pt) | 2014-11-04 |
| BRPI0821508B1 BRPI0821508B1 (pt) | 2018-12-26 |
Family
ID=40755894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821508A BRPI0821508B1 (pt) | 2007-12-11 | 2008-12-11 | cultura celular compreendendo uma cianobactéria recombinante da espécie synechococcus elongatus e método para converter carbono inorgânico em ácidos graxos. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090298143A1 (pt) |
| EP (1) | EP2231864B1 (pt) |
| JP (1) | JP5465183B2 (pt) |
| CN (1) | CN101952452B (pt) |
| AU (1) | AU2008335089B2 (pt) |
| BR (1) | BRPI0821508B1 (pt) |
| MX (1) | MX2010006539A (pt) |
| MY (1) | MY154028A (pt) |
| WO (1) | WO2009076559A1 (pt) |
| ZA (1) | ZA201004253B (pt) |
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| TW200826924A (en) * | 2006-09-08 | 2008-07-01 | Kaneka Corp | Composition containing reduced coenzyme Q10 and lysolecithin |
| US8272669B2 (en) * | 2006-10-24 | 2012-09-25 | Timothy J. Flynn | Label assembly for applying a label to an object |
| CN104212844A (zh) | 2007-06-01 | 2014-12-17 | 索拉兹米公司 | 在微生物中生产油 |
| MX2010006539A (es) | 2007-12-11 | 2011-02-23 | Synthetic Genomics Inc | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. |
| US8048654B2 (en) | 2010-06-09 | 2011-11-01 | Joule Unlimited Technologies, Inc. | Methods and compositions for the recombinant biosynthesis of fatty acids and esters |
| AU2013201607B2 (en) * | 2008-04-28 | 2015-03-12 | Naturally Scientific Technologies Limited | Production of biofuel from tissue culture sources |
| GB0807619D0 (en) * | 2008-04-28 | 2008-06-04 | Whitton Peter A | Production of bio fuels from plant tissue culture sources |
| WO2010011754A2 (en) * | 2008-07-22 | 2010-01-28 | Board Of Regents, The University Of Texas System | Continuous production and excretion of waxy products from photosynthetic organisms |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| WO2010048568A1 (en) | 2008-10-23 | 2010-04-29 | Targeted Growth, Inc. | Modified photosynthetic microorganisms for producing triglycerides |
| EP2370554B1 (en) | 2008-11-28 | 2019-05-15 | Corbion Biotech, Inc. | Manufacturing of tailored oils in recombinant heterotrophic microorganisms |
| US8835137B2 (en) * | 2008-12-23 | 2014-09-16 | Matrix Genetics, Llc | Modified photosynthetic microorganisms with reduced glycogen and their use in producing carbon-based products |
| WO2011008565A1 (en) * | 2009-06-29 | 2011-01-20 | Synthetic Genomics, Inc. | Acyl-acp thioesterase genes and uses therefor |
| WO2011011568A2 (en) * | 2009-07-24 | 2011-01-27 | The Regenst Of The University Of California | Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms |
| WO2011127069A1 (en) | 2010-04-06 | 2011-10-13 | Targeted Growth, Inc. | Modified photosynthetic microorganisms for producing lipids |
| JP2011246605A (ja) * | 2010-05-26 | 2011-12-08 | Hitachi Plant Technologies Ltd | バイオ燃料製造方法 |
| EP2576800B1 (en) * | 2010-05-28 | 2019-01-30 | Corbion Biotech, Inc. | Method for producing oils from Prototheca |
| AU2011323288B2 (en) | 2010-11-03 | 2016-05-26 | Corbion Biotech, Inc. | Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods |
| WO2012071439A1 (en) * | 2010-11-22 | 2012-05-31 | The Regents Of The University Of California | Host cells and methods for producing diacid compounds |
| EP2655615A4 (en) | 2010-12-23 | 2014-04-23 | Exxonmobil Res & Eng Co | PROKARYOTIC ACYL ACP THIOESTERASES FOR THE PREPARATION OF FATTY ACIDS IN GENETICALLY MODIFIED MICROORGANISMS |
| US9187726B2 (en) * | 2010-12-23 | 2015-11-17 | Exxonmobil Research And Engineering Company | Culturing a microorganism in a medium with an elevated level of a carboxylate counterion source |
| AU2012212079B2 (en) | 2011-02-02 | 2016-07-28 | Corbion Biotech, Inc. | Tailored oils produced from recombinant oleaginous microorganisms |
| US20130040340A1 (en) | 2011-02-07 | 2013-02-14 | E. I. Du Pont De Nemours And Company | Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms |
| WO2012135668A1 (en) | 2011-03-31 | 2012-10-04 | Exxonmobil Research And Engineering Company | Metabolic pathway targeting by transcription factor overexpression |
| MX339607B (es) | 2011-05-06 | 2016-05-31 | Solazyme Inc | Microorganismos geneticamente modificados que metabolizan xilosa. |
| US20140230091A1 (en) * | 2011-06-28 | 2014-08-14 | Brookhaven Science Associates, Llc | Modified plants with increased oil content |
| MX2013015327A (es) | 2011-06-30 | 2014-01-31 | Exxonmobil Res & Eng Co | Regulacion de genes toxina y antitoxina para contencion biologica. |
| US9399768B2 (en) | 2011-07-27 | 2016-07-26 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl-acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| US8951762B2 (en) | 2011-07-27 | 2015-02-10 | Iowa State University Research Foundation, Inc. | Materials and methods for using an acyl—acyl carrier protein thioesterase and mutants and chimeras thereof in fatty acid synthesis |
| DE102011110946A1 (de) | 2011-08-15 | 2016-01-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen |
| DE102011110945A1 (de) | 2011-08-15 | 2013-02-21 | Evonik Degussa Gmbh | Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt |
| CN103975070A (zh) | 2011-09-27 | 2014-08-06 | 艾克森美孚研究与工程公司 | 酰基-酰基载体蛋白(acyl-acp)蜡酯合酶 |
| PT2814972T (pt) | 2012-02-24 | 2020-06-16 | Exxonmobil Res & Eng Co | Produção melhorada de ácidos gordos e derivados de ácidos gordos por micro-organismos recombinantes |
| US9096834B2 (en) | 2012-02-24 | 2015-08-04 | Exxonmobil Research And Engineering Company | Recombinant microorganisms comprising thioesterase and lysophosphatidic acid acyltransferase genes for fatty acid production |
| US8962299B2 (en) | 2012-02-29 | 2015-02-24 | Exxonmobil Research And Engineering Company | Four-gene pathway for wax ester synthesis |
| US9719114B2 (en) | 2012-04-18 | 2017-08-01 | Terravia Holdings, Inc. | Tailored oils |
| EP2839018B1 (en) | 2012-04-18 | 2019-06-05 | Corbion Biotech, Inc. | Tailored oils |
| US9181568B2 (en) | 2012-04-23 | 2015-11-10 | Exxonmobil Research And Engineering Company | Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases |
| EP2929030B1 (en) * | 2012-12-04 | 2018-10-31 | ExxonMobil Research and Engineering Company | Tetraselmis promoters and terminators for use in eukaryotic cells |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| US9249252B2 (en) | 2013-04-26 | 2016-02-02 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
| DE102013208228A1 (de) | 2013-05-06 | 2014-11-06 | Siemens Aktiengesellschaft | Verfahren zum Kultivieren eines Mikroorganismus in einer in vitro Kultur und Verfahren zum Herstellen eines Sekundärmetabolits |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| CN105829521A (zh) | 2013-10-04 | 2016-08-03 | 索拉兹米公司 | 定制油 |
| JP6341676B2 (ja) * | 2014-01-31 | 2018-06-13 | 花王株式会社 | 改変シアノバクテリア |
| WO2015149026A1 (en) | 2014-03-28 | 2015-10-01 | Solazyme, Inc. | Lauric ester compositions |
| EP3167053B1 (en) | 2014-07-10 | 2019-10-09 | Corbion Biotech, Inc. | Novel ketoacyl acp synthase genes and uses thereof |
| KR101735632B1 (ko) * | 2014-12-10 | 2017-05-16 | 한국과학기술연구원 | 시아노박테리아 발현 벡터 |
| US10287612B2 (en) | 2014-12-22 | 2019-05-14 | Kao Corporation | Modified cyanobacteria |
| JP6568718B2 (ja) * | 2015-05-22 | 2019-08-28 | 花王株式会社 | 脂質の製造方法 |
| JP6587468B2 (ja) | 2015-09-11 | 2019-10-09 | 花王株式会社 | 脂質の製造方法 |
| EP3377057A4 (en) | 2016-01-07 | 2018-12-05 | Conagen Inc. | Methods of making capsinoids by biosynthetic processes |
| US10418697B2 (en) * | 2016-02-25 | 2019-09-17 | Toshiba Client Solutions Co. Ltd. | Antenna apparatus and electronic device |
| JP6734112B2 (ja) | 2016-05-10 | 2020-08-05 | 花王株式会社 | 脂質の製造方法 |
| HUE056799T2 (hu) | 2016-07-19 | 2022-03-28 | Conagen Inc | Módszer specifikus természetes kapszaicinoidok mikrobiális elõállítására |
| JP6971607B2 (ja) * | 2016-12-19 | 2021-11-24 | 花王株式会社 | 脂質の製造方法 |
| EP3559219A4 (en) * | 2016-12-22 | 2020-09-09 | Conagen Inc. | PROCESS FOR THE MICROBIAL PRODUCTION OF 8-METHYL NONANOIC ACID |
| JP6934303B2 (ja) | 2017-02-08 | 2021-09-15 | 花王株式会社 | 脂肪族アルコールの生産方法 |
| EP3794017A4 (en) | 2018-05-17 | 2022-03-09 | Lumen Bioscience, Inc. | ARTHROSPIRA PLATENSIS ORAL VACCINE DELIVERY PLATFORM |
| US12252513B2 (en) | 2018-07-16 | 2025-03-18 | Lumen Bioscience, Inc. | Thermostable phycobiliproteins produced from recombinant arthrospira |
| AU2020298626A1 (en) | 2019-07-03 | 2022-02-24 | Lumen Bioscience, Inc. | Arthrospira platensis non-parenteral therapeutic delivery platform |
| JP7551990B2 (ja) * | 2020-08-28 | 2024-09-18 | 大成建設株式会社 | 遊離脂肪酸の分離方法と回収方法 |
| US11336975B1 (en) | 2021-02-01 | 2022-05-17 | Shure Acquisition Holdings, Inc. | Wearable device with detune-resilient antenna |
| JP7646964B2 (ja) * | 2021-08-20 | 2025-03-18 | 大成建設株式会社 | 遊離脂肪酸の回収方法、回収システム |
| GB2617381A (en) | 2022-04-07 | 2023-10-11 | Phycobloom Ltd | Engineered photosynthetic organisms |
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| US5298421A (en) * | 1990-04-26 | 1994-03-29 | Calgene, Inc. | Plant medium-chain-preferring acyl-ACP thioesterases and related methods |
| US5179219A (en) * | 1990-11-19 | 1993-01-12 | Uop | Process for separating fatty acids and triglycerides |
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| JP2729883B2 (ja) * | 1992-10-07 | 1998-03-18 | 工業技術院長 | 藍藻を用いる有機分泌物の製造方法 |
| US6150512A (en) * | 1995-05-15 | 2000-11-21 | Yuan; Ling | Engineering plant thioesterases and disclosure of plant thioesterases having novel substrate specificity |
| CA2281953C (en) | 1997-02-19 | 2012-11-27 | Enol Energy Inc. | Genetically modified cyanobacteria for the production of ethanol |
| US6495140B1 (en) * | 1998-01-12 | 2002-12-17 | Her Majesty In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Canada | Process for the isolation, recovery and purification of non-polar extractives |
| AU5850000A (en) * | 1999-07-07 | 2001-01-30 | Kyowa Hakko Kogyo Co. Ltd. | Process for producing hydroxylated fatty acid and delta-lactone |
| PL207026B1 (pl) * | 2000-02-09 | 2010-10-29 | Basf Ag | Wyizolowany kwas nukleinowy, konstrukt genowy zawierający ten kwas, sekwencja aminokwasowa kodowana przez wyizolowaną sekwencję tego kwasu nukleinowego, wektor zawierający kwas nukleinowy lub konstrukt genowy, roślina transgeniczna lub mikroorganizm transgeniczny zawierający kwas nukleinowy, konstrukt genowy lub wektor, przeciwciało specyficznie wiążące się z polipeptydem kodowanym przez kwas nukleinowy, cząsteczka antysensownego kwasu nukleinowego oraz sposób wytwarzania wielonienasyconych kwasów tłuszczowych (PUFA) |
| JP4071622B2 (ja) * | 2000-09-28 | 2008-04-02 | バイオリジナル フード アンド サイエンス コーポレーション | 脂肪酸不飽和化酵素ファミリーのメンバーであるfad4、fad5、fad5−2およびfad6、ならびにそれらの使用方法 |
| BRPI0506811A (pt) * | 2004-02-13 | 2008-07-15 | Martek Biosciences Corp | sintetase de ácido graxo (fas) de schizochytrium e produtos e métodos correlatos |
| EP1752532A1 (en) | 2005-08-09 | 2007-02-14 | Helmholtz-Zentrum für Infektionsforschung GmbH | Extracellular polyhydroxyalkanoates produced by genetically engineered microorganisms |
| US9297028B2 (en) * | 2005-09-29 | 2016-03-29 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US7470532B2 (en) * | 2005-10-19 | 2008-12-30 | E.I. Du Pont De Nemours And Company | Mortierella alpina C16/18 fatty acid elongase |
| WO2008119082A2 (en) * | 2007-03-28 | 2008-10-02 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
| ES2528482T3 (es) * | 2006-05-19 | 2015-02-10 | Ls9, Inc. | Producción de ácidos grasos y derivados de los mismos |
| CN104212844A (zh) | 2007-06-01 | 2014-12-17 | 索拉兹米公司 | 在微生物中生产油 |
| MX2010006539A (es) | 2007-12-11 | 2011-02-23 | Synthetic Genomics Inc | Secrecion de acidos grasos por parte de microorganismos fotosinteticos. |
| WO2010033921A2 (en) | 2008-09-19 | 2010-03-25 | President And Fellows Of Harvard College | Photoautotrophic adipogenesis technology (phat) |
-
2008
- 2008-12-11 MX MX2010006539A patent/MX2010006539A/es unknown
- 2008-12-11 MY MYPI2010002698A patent/MY154028A/en unknown
- 2008-12-11 WO PCT/US2008/086485 patent/WO2009076559A1/en not_active Ceased
- 2008-12-11 CN CN200880126568.0A patent/CN101952452B/zh not_active Expired - Fee Related
- 2008-12-11 JP JP2010538169A patent/JP5465183B2/ja not_active Expired - Fee Related
- 2008-12-11 BR BRPI0821508A patent/BRPI0821508B1/pt not_active IP Right Cessation
- 2008-12-11 EP EP08860168.7A patent/EP2231864B1/en not_active Not-in-force
- 2008-12-11 AU AU2008335089A patent/AU2008335089B2/en not_active Ceased
- 2008-12-11 US US12/333,280 patent/US20090298143A1/en not_active Abandoned
-
2010
- 2010-06-15 ZA ZA2010/04253A patent/ZA201004253B/en unknown
-
2011
- 2011-12-29 US US13/340,350 patent/US10233470B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MY154028A (en) | 2015-04-30 |
| MX2010006539A (es) | 2011-02-23 |
| US20130005003A1 (en) | 2013-01-03 |
| EP2231864A4 (en) | 2011-02-02 |
| ZA201004253B (en) | 2011-08-31 |
| CN101952452A (zh) | 2011-01-19 |
| CN101952452B (zh) | 2014-07-09 |
| AU2008335089B2 (en) | 2014-06-26 |
| EP2231864B1 (en) | 2017-05-24 |
| WO2009076559A8 (en) | 2010-05-20 |
| JP5465183B2 (ja) | 2014-04-09 |
| US10233470B2 (en) | 2019-03-19 |
| US20090298143A1 (en) | 2009-12-03 |
| AU2008335089A1 (en) | 2009-06-18 |
| BRPI0821508B1 (pt) | 2018-12-26 |
| EP2231864A1 (en) | 2010-09-29 |
| WO2009076559A1 (en) | 2009-06-18 |
| JP2011505838A (ja) | 2011-03-03 |
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