BRPI0906261A2 - "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" - Google Patents
"métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente"Info
- Publication number
- BRPI0906261A2 BRPI0906261A2 BRPI0906261-0A BRPI0906261A BRPI0906261A2 BR PI0906261 A2 BRPI0906261 A2 BR PI0906261A2 BR PI0906261 A BRPI0906261 A BR PI0906261A BR PI0906261 A2 BRPI0906261 A2 BR PI0906261A2
- Authority
- BR
- Brazil
- Prior art keywords
- patient sample
- asthma subtype
- diagnosing
- methods
- therapeutic agent
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 2
- 239000013610 patient sample Substances 0.000 title 2
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7257208P | 2008-03-31 | 2008-03-31 | |
| US4148008P | 2008-04-01 | 2008-04-01 | |
| US12838308P | 2008-05-20 | 2008-05-20 | |
| US20539209P | 2009-01-16 | 2009-01-16 | |
| PCT/US2009/039033 WO2009124090A1 (en) | 2008-03-31 | 2009-03-31 | Compositions and methods for treating and diagnosing asthma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0906261A2 true BRPI0906261A2 (pt) | 2015-07-07 |
Family
ID=40695508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0906261-0A BRPI0906261A2 (pt) | 2008-03-31 | 2009-03-31 | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110123530A1 (pt) |
| EP (2) | EP2631302A3 (pt) |
| JP (3) | JP6161233B2 (pt) |
| KR (2) | KR102070761B1 (pt) |
| CN (2) | CN102232113A (pt) |
| AU (1) | AU2009231733B2 (pt) |
| BR (1) | BRPI0906261A2 (pt) |
| CA (1) | CA2718120A1 (pt) |
| IL (1) | IL208366A0 (pt) |
| MX (1) | MX348362B (pt) |
| NZ (2) | NZ588853A (pt) |
| PH (1) | PH12018500045A1 (pt) |
| RU (2) | RU2607569C2 (pt) |
| SG (1) | SG2014014138A (pt) |
| WO (1) | WO2009124090A1 (pt) |
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| US7291331B1 (en) | 2002-09-11 | 2007-11-06 | La Jolla Institute For Allergy And Immunology | Methods of treating OX40 medicated recall immune responses |
| PL3718564T3 (pl) | 2003-12-23 | 2024-03-18 | Genentech, Inc. | Nowe przeciwciała anty-IL 13 i ich zastosowania |
| BRPI1016061A2 (pt) | 2009-05-28 | 2016-09-13 | Glaxo Group Ltd | "proteína de ligação de antígeno, célula hospedeira transfectada ou transformada recombinante, composição farmacêutica, método de tratamento de um paciente humano, uso de uma proteína de ligação de antígeno, método para a redução da agregação de um domínio variável simples de imunoglobulina, vk dab humano derivado de uma estrutura da linha germinativa, e, domínio variável simples de imunoglobulina." |
| KR101135173B1 (ko) | 2010-01-19 | 2012-04-16 | 한국생명공학연구원 | Sh3rf2 발현 또는 활성 억제제를 함유하는 암의 예방 또는 치료용 조성물 |
| KR101180879B1 (ko) | 2010-06-21 | 2012-09-07 | 중앙대학교 산학협력단 | 천식 진단용 유전자 마커 및 이를 이용한 천식 진단에 필요한 정보를 제공하는 방법 |
| KR101366612B1 (ko) | 2010-10-12 | 2014-02-25 | 한국생명공학연구원 | 시스타틴 c를 유효성분으로 함유하는 천식 예방 및 치료용 조성물 |
| RU2578468C2 (ru) | 2010-12-16 | 2016-03-27 | Дженентек, Инк. | Способы диагностики и лечения, связанные с ингибированием th2 |
| AU2013204900B2 (en) * | 2010-12-16 | 2016-11-10 | Genentech, Inc. | Diagnosis and treatments relating to TH2 inhibition |
| WO2012178188A2 (en) * | 2011-06-23 | 2012-12-27 | Children's Hospital Medical Center | Molecular diagnostic panel of eosinophilic gastrointestinal disorders |
| US9732151B2 (en) * | 2011-11-03 | 2017-08-15 | Merck Sharp & Dohme Corp. | Biomarkers for TSLP treatment |
| JP6192122B2 (ja) * | 2012-01-09 | 2017-09-06 | スージョウ マイクロダイアグ バイオメディスン カンパニー リミテッド | 結腸直腸癌診断および予測のためのバイオマーカー |
| CN107099581B (zh) * | 2012-03-27 | 2021-07-13 | 弗·哈夫曼-拉罗切有限公司 | 预测、诊断和治疗特发性肺纤维化的方法 |
| AR091069A1 (es) | 2012-05-18 | 2014-12-30 | Amgen Inc | Proteinas de union a antigeno dirigidas contra el receptor st2 |
| EP2708898A1 (de) | 2012-09-14 | 2014-03-19 | Sterna Biologicals GmbH & Co. Kg | Verfahren zur Diagnose eines molekularen Phänotyps eines an einer mit chronischen Entzündungen einhergehenden Erkrankung leidenden Patienten |
| US10132809B2 (en) | 2012-10-10 | 2018-11-20 | Rhote Island Hospital | Differential expression of protein markers for the diagnosis and treatment of eosinophilic esophagitis |
| DK3199552T3 (da) | 2012-11-20 | 2020-03-30 | Sanofi Sa | Anti-ceacam5-antistoffer og anvendelser heraf |
| EP2931920B1 (en) * | 2012-12-14 | 2018-03-07 | The University of Newcastle | Biomarkers of asthma inflammatory phenotypes and response to therapy |
| EP2968454B1 (en) * | 2013-03-15 | 2019-02-13 | Regeneron Pharmaceuticals, Inc. | Il-33 antagonists and uses thereof |
| WO2015009996A1 (en) * | 2013-07-19 | 2015-01-22 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating eosinophilic esophagitis |
| CN120904322A (zh) | 2013-09-13 | 2025-11-07 | 豪夫迈·罗氏有限公司 | 包含纯化的重组多肽的方法和组合物 |
| RU2016107435A (ru) | 2013-09-13 | 2017-10-18 | Дженентек, Инк. | Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты |
| US20160304866A1 (en) * | 2013-09-27 | 2016-10-20 | Aqua Therapeutics Co., Ltd. | Drug for Disease Caused by Expression of Periostin Except Eye Disease, and Use Thereof |
| AR098155A1 (es) * | 2013-10-23 | 2016-05-04 | Genentech Inc | Métodos para diagnosticar y tratar trastornos eosinofílicos |
| CA2937387A1 (en) | 2014-01-27 | 2015-07-30 | Medimmune, Llc | Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung |
| CN103792375B (zh) * | 2014-01-29 | 2017-07-07 | 华中科技大学同济医学院附属同济医院 | 外周血白细胞介素25水平在哮喘分型中的应用及分型方法 |
| HK1232290A1 (zh) | 2014-02-07 | 2018-01-05 | Medimmune, Llc | 检测人类骨膜蛋白的新型测定 |
| WO2015126750A1 (en) * | 2014-02-19 | 2015-08-27 | Array Biopharma Inc. | BIOMARKERS PREDICTIVE OF RESPONSIVENESS TO TREATMENT WITH A CRTh2 INHIBITOR |
| UA117608C2 (uk) | 2014-02-21 | 2018-08-27 | Дженентек, Інк. | Спосіб лікування еозинофільного захворювання у пацієнта шляхом застосування біспецифічного анти-il-13/il-17 антитіла |
| JP7231326B2 (ja) * | 2014-11-10 | 2023-03-01 | ジェネンテック, インコーポレイテッド | Il-33媒介性障害のための治療及び診断方法 |
| AU2016205188A1 (en) | 2015-01-09 | 2017-06-22 | Medimmune, Llc | Assay to detect human DPP-4 |
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| JP6531629B2 (ja) * | 2015-11-17 | 2019-06-19 | 株式会社ダイフク | 物品搬送設備 |
| WO2017123401A1 (en) | 2016-01-13 | 2017-07-20 | Children's Hospital Medical Center | Compositions and methods for treating allergic inflammatory conditions |
| EP3417079A4 (en) * | 2016-02-17 | 2019-07-10 | Icahn School of Medicine at Mount Sinai | NASAL BIOMARKERS FOR ASTHMA |
| WO2017147492A1 (en) * | 2016-02-26 | 2017-08-31 | National Jewish Health | Methods of detecting and treating airway inflammatory diseases |
| JP6871948B2 (ja) | 2016-04-27 | 2021-05-19 | アッヴィ・インコーポレイテッド | 抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法 |
| MX2018013038A (es) | 2016-04-27 | 2019-03-28 | Pfizer | Anticuerpos anti-il-33, composiciones, metodos y usos de los mismos. |
| TW201842933A (zh) * | 2017-05-05 | 2018-12-16 | 瑞士商諾華公司 | 使用il-17拮抗劑選擇性治療氣喘的方法 |
| KR101967826B1 (ko) * | 2017-06-30 | 2019-04-11 | 아주대학교산학협력단 | 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법 |
| ES2753602R1 (es) * | 2017-07-19 | 2020-05-20 | Fundacion Instituto De Investig Sanitaria Fundacion Jimenez Diaz | Biomarcadores diferenciales de asma |
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| US12297501B2 (en) | 2019-02-25 | 2025-05-13 | Children's Hospital Medical Center | Methods for diagnosing and treating eosinophilic gastritis |
| US20220146500A1 (en) * | 2019-02-27 | 2022-05-12 | Yale University | Compositions and methods for enhancing mucosal immunity |
| CN110672858A (zh) * | 2019-10-18 | 2020-01-10 | 郑湘榕 | 一种检测试剂盒在制备用于婴幼儿喘息性疾病的检测试剂盒中的应用 |
| CN111690061B (zh) * | 2020-06-28 | 2022-08-23 | 中国人民解放军东部战区疾病预防控制中心 | 人源化抗鼠疫耶尔森菌抗原f1的抗体及应用 |
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- 2009-03-31 EP EP13162396.9A patent/EP2631302A3/en not_active Withdrawn
- 2009-03-31 MX MX2010010746A patent/MX348362B/es active IP Right Grant
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- 2009-03-31 CA CA2718120A patent/CA2718120A1/en not_active Abandoned
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|---|---|
| RU2607569C2 (ru) | 2017-01-10 |
| AU2009231733B2 (en) | 2015-12-24 |
| SG2014014138A (en) | 2014-07-30 |
| MX2010010746A (es) | 2010-10-15 |
| IL208366A0 (en) | 2010-12-30 |
| JP2011523350A (ja) | 2011-08-11 |
| JP6037515B2 (ja) | 2016-12-07 |
| JP2014204725A (ja) | 2014-10-30 |
| NZ588853A (en) | 2013-07-26 |
| RU2014110413A (ru) | 2015-09-27 |
| CN112481367A (zh) | 2021-03-12 |
| CN102232113A (zh) | 2011-11-02 |
| MX348362B (es) | 2017-06-07 |
| KR102070761B1 (ko) | 2020-01-29 |
| EP2271770A1 (en) | 2011-01-12 |
| EP2271770B1 (en) | 2018-08-22 |
| JP2015166738A (ja) | 2015-09-24 |
| CA2718120A1 (en) | 2009-10-08 |
| PH12018500045A1 (en) | 2019-10-28 |
| AU2009231733A1 (en) | 2009-10-08 |
| NZ601815A (en) | 2014-10-31 |
| KR20100131003A (ko) | 2010-12-14 |
| KR20170063996A (ko) | 2017-06-08 |
| RU2010144502A (ru) | 2012-05-10 |
| EP2631302A3 (en) | 2014-01-08 |
| WO2009124090A1 (en) | 2009-10-08 |
| JP6161233B2 (ja) | 2017-07-12 |
| EP2631302A2 (en) | 2013-08-28 |
| US20110123530A1 (en) | 2011-05-26 |
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