BRPI0906261A2 - "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" - Google Patents
"métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente"Info
- Publication number
- BRPI0906261A2 BRPI0906261A2 BRPI0906261-0A BRPI0906261A BRPI0906261A2 BR PI0906261 A2 BRPI0906261 A2 BR PI0906261A2 BR PI0906261 A BRPI0906261 A BR PI0906261A BR PI0906261 A2 BRPI0906261 A2 BR PI0906261A2
- Authority
- BR
- Brazil
- Prior art keywords
- patient sample
- asthma subtype
- diagnosing
- methods
- therapeutic agent
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 2
- 239000013610 patient sample Substances 0.000 title 2
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7257208P | 2008-03-31 | 2008-03-31 | |
| US4148008P | 2008-04-01 | 2008-04-01 | |
| US12838308P | 2008-05-20 | 2008-05-20 | |
| US20539209P | 2009-01-16 | 2009-01-16 | |
| PCT/US2009/039033 WO2009124090A1 (en) | 2008-03-31 | 2009-03-31 | Compositions and methods for treating and diagnosing asthma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0906261A2 true BRPI0906261A2 (pt) | 2015-07-07 |
Family
ID=40695508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0906261-0A BRPI0906261A2 (pt) | 2008-03-31 | 2009-03-31 | "métodos de diagnóstico de um subtipo de asma em uma amostra de paciente, usos de um agente terapêutico e kits de diagnóstico de um subtipo de asma em uma amostra de paciente" |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20110123530A1 (pt) |
| EP (2) | EP2271770B1 (pt) |
| JP (3) | JP6161233B2 (pt) |
| KR (2) | KR102070761B1 (pt) |
| CN (2) | CN112481367A (pt) |
| AU (1) | AU2009231733B2 (pt) |
| BR (1) | BRPI0906261A2 (pt) |
| CA (1) | CA2718120A1 (pt) |
| IL (1) | IL208366A0 (pt) |
| MX (1) | MX348362B (pt) |
| NZ (2) | NZ601815A (pt) |
| PH (1) | PH12018500045A1 (pt) |
| RU (2) | RU2607569C2 (pt) |
| SG (1) | SG2014014138A (pt) |
| WO (1) | WO2009124090A1 (pt) |
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| DK2805728T3 (da) | 2003-12-23 | 2020-04-20 | Genentech Inc | Hidtil ukendte anti-IL13-antistoffer og anvendelser deraf |
| WO2010136481A1 (en) | 2009-05-28 | 2010-12-02 | Glaxo Group Limited | Il-13 binding protein |
| KR101135173B1 (ko) | 2010-01-19 | 2012-04-16 | 한국생명공학연구원 | Ｓｈ３ｒｆ２ 발현 또는 활성 억제제를 함유하는 암의 예방 또는 치료용 조성물 |
| KR101180879B1 (ko) | 2010-06-21 | 2012-09-07 | 중앙대학교 산학협력단 | 천식 진단용 유전자 마커 및 이를 이용한 천식 진단에 필요한 정보를 제공하는 방법 |
| KR101366612B1 (ko) | 2010-10-12 | 2014-02-25 | 한국생명공학연구원 | 시스타틴 ｃ를 유효성분으로 함유하는 천식 예방 및 치료용 조성물 |
| JP6005657B2 (ja) * | 2010-12-16 | 2016-10-12 | ジェネンテック， インコーポレイテッド | Ｔｈ２阻害に関連する診断及び治療 |
| AU2013204894B2 (en) * | 2010-12-16 | 2016-11-10 | Genentech, Inc. | Diagnosis and treatments relating to TH2 inhibition |
| AU2012272559C1 (en) | 2011-06-23 | 2017-04-20 | Children's Hospital Medical Center | Molecular diagnostic panel of eosinophilic gastrointestinal disorders |
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| EP2708898A1 (de) | 2012-09-14 | 2014-03-19 | Sterna Biologicals GmbH & Co. Kg | Verfahren zur Diagnose eines molekularen Phänotyps eines an einer mit chronischen Entzündungen einhergehenden Erkrankung leidenden Patienten |
| WO2014059178A1 (en) * | 2012-10-10 | 2014-04-17 | Rhode Island Hospital | Differential expression of novel protein markers for the diagnosis and treatment of eosinophilic esophagitis |
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| EP2931920B1 (en) * | 2012-12-14 | 2018-03-07 | The University of Newcastle | Biomarkers of asthma inflammatory phenotypes and response to therapy |
| KR20150127591A (ko) * | 2013-03-15 | 2015-11-17 | 리제너론 파아마슈티컬스, 인크. | Il-33 길항제 및 이의 용도 |
| WO2015009996A1 (en) * | 2013-07-19 | 2015-01-22 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating eosinophilic esophagitis |
| SG10201802525QA (en) | 2013-09-13 | 2018-04-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| KR102332302B1 (ko) | 2013-09-13 | 2021-12-01 | 제넨테크, 인크. | 세포주에서 숙주 세포 단백질 및 재조합 폴리펩티드 생성물을 검출 및 정량화하기 위한 조성물 및 방법 |
| US20160304866A1 (en) * | 2013-09-27 | 2016-10-20 | Aqua Therapeutics Co., Ltd. | Drug for Disease Caused by Expression of Periostin Except Eye Disease, and Use Thereof |
| BR112016008694A2 (pt) * | 2013-10-23 | 2017-10-03 | Genentech Inc | Métodos de previsão da reação de pacientes com asma, de previsão da capacidade de reação de pacientes com asma, de identificação de pacientes com asma, de tratamento de pacientes portadores de asma e de tratamento de asma, uso de um kit e kit |
| EP3099323A4 (en) | 2014-01-27 | 2017-10-04 | Medlmmune, LLC | Dipeptidyl peptidase-4 (dpp4/cd26) as a peripheral biomarker of il-13 activation in asthmatic lung |
| CN103792375B (zh) * | 2014-01-29 | 2017-07-07 | 华中科技大学同济医学院附属同济医院 | 外周血白细胞介素25水平在哮喘分型中的应用及分型方法 |
| MX2016009490A (es) | 2014-02-07 | 2017-05-12 | Medimmune Llc | Ensayo novedoso para detectar periostina humana. |
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| EA037960B1 (ru) | 2016-04-27 | 2021-06-15 | Эббви Инк. | Способ лечения эозинофильного эзофагита с применением антитела против il-13 |
| TW201842933A (zh) | 2017-05-05 | 2018-12-16 | 瑞士商諾華公司 | 使用il-17拮抗劑選擇性治療氣喘的方法 |
| KR101967826B1 (ko) * | 2017-06-30 | 2019-04-11 | 아주대학교산학협력단 | 페리오스틴을 이용한 아이소사이아네이트 직업성 천식의 진단방법 |
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| CN109161590B (zh) * | 2017-08-23 | 2022-03-18 | 中南大学 | 整合素β4基因DNA甲基化位点在制备哮喘和或COPD早期诊断的生物标志物的应用 |
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| CN110672858A (zh) * | 2019-10-18 | 2020-01-10 | 郑湘榕 | 一种检测试剂盒在制备用于婴幼儿喘息性疾病的检测试剂盒中的应用 |
| CN111690061B (zh) * | 2020-06-28 | 2022-08-23 | 中国人民解放军东部战区疾病预防控制中心 | 人源化抗鼠疫耶尔森菌抗原f1的抗体及应用 |
| TWI896700B (zh) * | 2020-07-10 | 2025-09-11 | 大陸商上海濟煜醫藥科技有限公司 | 一種抗IgE的工程化抗體及其應用 |
| JP2022061491A (ja) * | 2020-10-06 | 2022-04-18 | 国立大学法人福井大学 | 慢性副鼻腔炎の患者を分類するためのデータの取得方法、およびその利用 |
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| KR20250017928A (ko) * | 2023-07-28 | 2025-02-04 | 재단법인 아산사회복지재단 | 객담 단백체를 이용한 생물학적 제제에 대한 천식 치료 반응성 예측을 위한 바이오마커 및 이의 용도 |
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- 2009-03-31 US US12/935,822 patent/US20110123530A1/en not_active Abandoned
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2631302A3 (en) | 2014-01-08 |
| JP2015166738A (ja) | 2015-09-24 |
| MX348362B (es) | 2017-06-07 |
| US20110123530A1 (en) | 2011-05-26 |
| KR20170063996A (ko) | 2017-06-08 |
| RU2607569C2 (ru) | 2017-01-10 |
| SG2014014138A (en) | 2014-07-30 |
| EP2271770A1 (en) | 2011-01-12 |
| KR20100131003A (ko) | 2010-12-14 |
| EP2271770B1 (en) | 2018-08-22 |
| NZ601815A (en) | 2014-10-31 |
| IL208366A0 (en) | 2010-12-30 |
| CN112481367A (zh) | 2021-03-12 |
| JP6161233B2 (ja) | 2017-07-12 |
| MX2010010746A (es) | 2010-10-15 |
| CN102232113A (zh) | 2011-11-02 |
| PH12018500045A1 (en) | 2019-10-28 |
| NZ588853A (en) | 2013-07-26 |
| JP2014204725A (ja) | 2014-10-30 |
| RU2014110413A (ru) | 2015-09-27 |
| RU2010144502A (ru) | 2012-05-10 |
| KR102070761B1 (ko) | 2020-01-29 |
| AU2009231733A1 (en) | 2009-10-08 |
| AU2009231733B2 (en) | 2015-12-24 |
| JP2011523350A (ja) | 2011-08-11 |
| EP2631302A2 (en) | 2013-08-28 |
| WO2009124090A1 (en) | 2009-10-08 |
| JP6037515B2 (ja) | 2016-12-07 |
| CA2718120A1 (en) | 2009-10-08 |
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