BRPI0907228A2 - Compostos de tienopiridazina, suas preparações, composições farmacêuticas e usos - Google Patents

Compostos de tienopiridazina, suas preparações, composições farmacêuticas e usos

Info

Publication number: BRPI0907228A2
Authority: BR; Brazil
Prior art keywords: preparations; pharmaceutical compositions; thienopyridazine; compounds; thienopyridazine compounds
Prior art date: 2008-01-08

Application number

BRPI0907228-4A

Other languages

English (en)

Inventor

Zhanggui Wu

Original Assignee

Zhe Jiang Medicine Co Ltd Xinchang Pharmaceutical Factory

Zhanggui Wu

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-08

Filing date

2009-01-07

Publication date

2015-07-14

2009-01-07 Application filed by Zhe Jiang Medicine Co Ltd Xinchang Pharmaceutical Factory, Zhanggui Wu filed Critical Zhe Jiang Medicine Co Ltd Xinchang Pharmaceutical Factory

2015-07-14 Publication of BRPI0907228A2 publication Critical patent/BRPI0907228A2/pt

2021-08-03 Publication of BRPI0907228B1 publication Critical patent/BRPI0907228B1/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Immunology (AREA)
Oncology (AREA)
Hematology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0907228-4A 2008-01-08 2009-01-07 Compostos de tienopiridazina, suas preparações, composições farmacêuticas e usos BRPI0907228B1 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
CN200810000936.9		2008-01-08
CN200810000936		2008-01-08
CN2009100003371A CN101481380B (zh)	2008-01-08	2009-01-06	噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途
CN200910000337.1		2009-01-06
PCT/CN2009/000021 WO2009092278A1 (zh)	2008-01-08	2009-01-07	噻吩并哒嗪类化合物及其制备方法、药物组合物及其用途

Publications (2)

Publication Number	Publication Date
BRPI0907228A2 true BRPI0907228A2 (pt)	2015-07-14
BRPI0907228B1 BRPI0907228B1 (pt)	2021-08-03

Family

ID=40878690

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0907228-4A BRPI0907228B1 (pt)	2008-01-08	2009-01-07	Compostos de tienopiridazina, suas preparações, composições farmacêuticas e usos

Country Status (11)

Country	Link
US (3)	US8962626B2 (pt)
EP (1)	EP2241569B1 (pt)
JP (1)	JP5456694B2 (pt)
KR (1)	KR101512530B1 (pt)
CN (1)	CN101481380B (pt)
AU (1)	AU2009207968B2 (pt)
BR (1)	BRPI0907228B1 (pt)
CA (1)	CA2711629C (pt)
MX (1)	MX2010007502A (pt)
RU (1)	RU2494103C2 (pt)
WO (1)	WO2009092278A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2481791T3 (es) *	2009-09-18	2014-07-31	Zhanggui Wu	Compuestos novedosos y uso terapéutico para la inhibición de proteína cinasa
CN105358155A (zh)	2013-05-10	2016-02-24	尼普斯阿波罗有限公司	Acc抑制剂和其用途
CA2911932A1 (en)	2013-05-10	2014-11-13	Nimbus Apollo, Inc.	Acc inhibitors and uses thereof
CA2911818A1 (en) *	2013-05-10	2014-11-13	Nimbus Apollo, Inc.	Acc inhibitors and uses thereof
MX2015015417A (es)	2013-05-10	2016-06-21	Nimbus Apollo Inc	Inhibidores de acetil-coa carboxilasa (acc) y usos de los mismos.
EP3483167A1 (en) *	2013-06-26	2019-05-15	AbbVie Inc.	Primary carboxamides as btk inhibitors
CN103288614B (zh) *	2013-06-27	2014-09-17	中国科学院昆明植物研究所	具有抗肿瘤活性的间苯三酚类化合物及其药物组合物
CA2928568A1 (en)	2013-07-26	2015-01-29	Update Pharma Inc.	Combinatorial methods to improve the therapeutic benefit of bisantrene
CN103694217A (zh) *	2013-12-20	2014-04-02	华东师范大学	一种2,4-二取代噻吩衍生物及其制备方法和应用
WO2021141974A2 (en) *	2020-01-07	2021-07-15	Fan Wu	Combination cancer therapy using chk inhibitor
US20230183259A1 (en) *	2020-04-17	2023-06-15	Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory	Crystal Form Of Thiofuran Pyridazine Compound, Preparation Method Therefor And Application Thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CO5200835A1 (es) *	1999-09-28	2002-09-27	Bayer Corp	Piridinas y piridacinas sustituidas con actividad de inhibicion de angiogenesis
AU2004265140A1 (en) *	2003-08-15	2005-02-24	Astrazeneca Ab	Substituted thiophenes and uses thereof
WO2005066163A2 (en) *	2004-01-05	2005-07-21	Astrazeneca Ab	Thiophene derivatives as chk 1 inihibitors
EP1745051A1 (en) *	2004-05-04	2007-01-24	F.Hoffmann-La Roche Ag	Thienopyridazines as ikk inhibitors
WO2006106326A1 (en) *	2005-04-06	2006-10-12	Astrazeneca Ab	Substituted heterocycles and their use as chk1, pdk1 and pak inhibitors
EP2038289A2 (en) *	2006-04-21	2009-03-25	Amgen Inc.	Thieno-[2,3-d]pyrimidine and thieno-pyridazine compounds and methods of use
JP2010525077A (ja) *	2007-04-25	2010-07-22	ブリストル−マイヤーズスクイブカンパニー	非塩基性メラニン凝集ホルモン受容体−１アンタゴニスト
WO2009003911A1 (en) *	2007-06-29	2009-01-08	4Sc Ag	Thiophene-imidazopyridines

2009
- 2009-01-06 CN CN2009100003371A patent/CN101481380B/zh active Active
- 2009-01-07 JP JP2010541010A patent/JP5456694B2/ja active Active
- 2009-01-07 US US12/811,898 patent/US8962626B2/en active Active
- 2009-01-07 BR BRPI0907228-4A patent/BRPI0907228B1/pt active IP Right Grant
- 2009-01-07 AU AU2009207968A patent/AU2009207968B2/en active Active
- 2009-01-07 RU RU2010128221/04A patent/RU2494103C2/ru active
- 2009-01-07 WO PCT/CN2009/000021 patent/WO2009092278A1/zh not_active Ceased
- 2009-01-07 EP EP09703313A patent/EP2241569B1/en active Active
- 2009-01-07 KR KR1020107017631A patent/KR101512530B1/ko not_active Expired - Fee Related
- 2009-01-07 US US12/349,888 patent/US8318740B2/en active Active
- 2009-01-07 CA CA2711629A patent/CA2711629C/en active Active
- 2009-01-07 MX MX2010007502A patent/MX2010007502A/es active IP Right Grant
2012
- 2012-11-02 US US13/668,197 patent/US9249154B2/en active Active

Also Published As

Publication number	Publication date
CA2711629C (en)	2017-10-24
AU2009207968A1 (en)	2009-07-30
JP2011508750A (ja)	2011-03-17
KR20100117069A (ko)	2010-11-02
EP2241569B1 (en)	2012-05-23
US8318740B2 (en)	2012-11-27
WO2009092278A8 (zh)	2010-07-22
CA2711629A1 (en)	2009-07-30
WO2009092278A1 (zh)	2009-07-30
BRPI0907228B1 (pt)	2021-08-03
US20090275585A1 (en)	2009-11-05
RU2494103C2 (ru)	2013-09-27
EP2241569A1 (en)	2010-10-20
US9249154B2 (en)	2016-02-02
JP5456694B2 (ja)	2014-04-02
RU2010128221A (ru)	2012-02-20
MX2010007502A (es)	2010-10-15
KR101512530B1 (ko)	2015-04-15
US20130143887A1 (en)	2013-06-06
CN101481380A (zh)	2009-07-15
US20110009415A1 (en)	2011-01-13
US8962626B2 (en)	2015-02-24
EP2241569A4 (en)	2011-01-12
CN101481380B (zh)	2012-10-17
AU2009207968B2 (en)	2014-04-24

Legal Events

Date	Code	Title	Description
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-10-30	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-10-15	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]	Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.
2020-10-20	B07E	Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2021-01-26	B06A	Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
2021-05-18	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2021-08-03	B16A	Patent or certificate of addition of invention granted	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 07/01/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

Publication	Publication Date	Title
BRPI0910503A2 (pt)	2015-09-29	compostos, composições farmacêuticas e respectivos usos.
BRPI1009372A2 (pt)	2016-05-31	compostos, composição farmacêutica e respectivos usos
BRPI0908021A2 (pt)	2015-07-21	Composto, composição farmacêutica, e, usos do composto ou da composição farmacêutica
BRPI0918360A2 (pt)	2017-10-10	composto, composição farmacêutica e usos de um composto
BRPI1009324A2 (pt)	2015-11-24	compostos e/ou farmaceuticamente aceitáveis dos mesmos, composição farmacêutica e respectivos usos
BRPI0906962A2 (pt)	2015-07-14	Composto, e, composição farmacêutica
BRPI0906556A2 (pt)	2015-07-07	Composto, e, composição farmacêutica
BRPI1010772A2 (pt)	2016-11-01	composto,e, composição farmacêutica.
BRPI0918652A2 (pt)	2015-08-25	Composições farmacêuticas e métodos de libração relacionadas.
BRPI0820381A2 (pt)	2015-05-19	Formulações farmacêuticas
BRPI1010621A2 (pt)	2016-06-21	derivado de imidazoquinolinonas, sua composição farmacêutica e seu uso
BRPI0915897A2 (pt)	2015-11-03	compostos derivados triazóis, composições farmacêuticas e combinações dos mesmos e seus usos
DK3492069T3 (da)	2022-03-14	Farmaceutiske sammensætninger omfattende jern-oxy-hydroxid
BRPI0917681A2 (pt)	2015-08-04	Composto, e, composição farmacêutica
BRPI0822337A2 (pt)	2015-06-16	Folatos, composições e usos dos mesmos
BR112012004335A2 (pt)	2015-09-08	composto, composição farmacêutica, e, uso do composto.
BR112012003842A2 (pt)	2016-03-22	composição farmacêutica, método de formulação e uso da mesma
DK2285357T3 (da)	2014-06-02	Farmaceutisk sammensætning omfattende brivaracetam
BR112012031226A2 (pt)	2018-03-06	composto, uso do composto, composição farmacêutica, e uso de composição farmacêutica
BRPI0807078A2 (pt)	2014-04-08	Composto, e, formulação farmacêutica
BR112012003800A2 (pt)	2016-11-22	composição, peptídeo, e formulação farmacêutica.
BRPI0921654A2 (pt)	2016-02-10	formulação farmacêutica
DK2285413T3 (da)	2012-08-27	Farmaceutisk sammensætning
BR112012000831A2 (pt)	2019-09-24	compostos, composições farmacêuticas e métodos relacionados
BRPI0921313A2 (pt)	2015-12-29	composição farmaucêutica