BRPI0909439A2 - preparação sólida de desintegração oral, e, método para suprimir a ruptura de grânulos finos - Google Patents

preparação sólida de desintegração oral, e, método para suprimir a ruptura de grânulos finos

Info

Publication number
BRPI0909439A2
BRPI0909439A2 BRPI0909439A BRPI0909439A BRPI0909439A2 BR PI0909439 A2 BRPI0909439 A2 BR PI0909439A2 BR PI0909439 A BRPI0909439 A BR PI0909439A BR PI0909439 A BRPI0909439 A BR PI0909439A BR PI0909439 A2 BRPI0909439 A2 BR PI0909439A2
Authority
BR
Brazil
Prior art keywords
solid preparation
fine granule
oral disintegration
suppressing fine
granule rupture
Prior art date
Application number
BRPI0909439A
Other languages
English (en)
Inventor
Takashi Kurasawa
Yasuko Watanabe
Yoshihiro Omachi
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40791576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0909439(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of BRPI0909439A2 publication Critical patent/BRPI0909439A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0909439A 2008-03-11 2009-03-10 preparação sólida de desintegração oral, e, método para suprimir a ruptura de grânulos finos BRPI0909439A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008061673 2008-03-11
JP2008334920 2008-12-26
PCT/JP2009/054983 WO2009113703A2 (en) 2008-03-11 2009-03-10 Orally-disintegrating solid preparation

Publications (1)

Publication Number Publication Date
BRPI0909439A2 true BRPI0909439A2 (pt) 2015-12-15

Family

ID=40791576

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909439A BRPI0909439A2 (pt) 2008-03-11 2009-03-10 preparação sólida de desintegração oral, e, método para suprimir a ruptura de grânulos finos

Country Status (26)

Country Link
US (2) US9241910B2 (pt)
EP (1) EP2254556A2 (pt)
JP (1) JP5604304B2 (pt)
KR (1) KR20100129761A (pt)
CN (2) CN104127368A (pt)
AR (1) AR070863A1 (pt)
AU (1) AU2009224254A1 (pt)
BR (1) BRPI0909439A2 (pt)
CA (1) CA2717947C (pt)
CL (1) CL2009000557A1 (pt)
CO (1) CO6321224A2 (pt)
CR (1) CR11709A (pt)
DO (1) DOP2010000273A (pt)
EA (1) EA021792B1 (pt)
EC (1) ECSP10010538A (pt)
GE (1) GEP20135845B (pt)
IL (1) IL207989A0 (pt)
MA (1) MA32174B1 (pt)
MX (1) MX2010009824A (pt)
MY (1) MY173730A (pt)
NZ (1) NZ588407A (pt)
PE (2) PE20091620A1 (pt)
TW (1) TWI441658B (pt)
UY (1) UY31698A (pt)
WO (1) WO2009113703A2 (pt)
ZA (1) ZA201006679B (pt)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY173730A (en) 2008-03-11 2020-02-18 Takeda Pharmaceuticals Co Orally-disintegrating solid preparation
CA2729015A1 (en) * 2008-06-26 2009-12-30 Mcneil-Ppc, Inc. Coated particles containing pharmaceutically active agents
JP5753661B2 (ja) 2009-01-26 2015-07-22 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース水分散液を用いた湿式造粒打錠法
EP2319504A1 (en) * 2009-11-07 2011-05-11 Laboratorios Del. Dr. Esteve, S.A. Pharmaceutical solid dosage form
US20130216617A1 (en) * 2010-06-29 2013-08-22 Cadila Healthcare Limited Pharmaceutical compositions of (r)-lansoprazole
JP2014501224A (ja) * 2010-12-27 2014-01-20 武田薬品工業株式会社 口腔内崩壊錠
CN102716097A (zh) * 2012-05-29 2012-10-10 浙江华海药业股份有限公司 控制口腔崩解片药物释放速率的方法
FI126168B (en) 2012-09-18 2016-07-29 Novaldmedical Ltd Oy A method for coating pharmaceutical substrates
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
AU2015290098B2 (en) 2014-07-17 2018-11-01 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
US20160106737A1 (en) 2014-10-20 2016-04-21 Pharmaceutical Manufacturing Research Services, Inc. Extended Release Abuse Deterrent Liquid Fill Dosage Form
EP3257511B1 (en) * 2015-02-10 2018-10-24 FUJIFILM Corporation Orally disintegrating tablet and method for manufacturing same
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US20190054029A1 (en) * 2016-02-23 2019-02-21 Nipro Corporation Pharmaceutical composition particles, orally disintegrating preparation including same, and method for producing pharmaceutical composition particles
US10751408B2 (en) 2016-02-23 2020-08-25 The Regents Of The University Of Colorado, A Body Corporate Compositions and methods for making and using thermostable immunogenic formulations with increased compatibility of use as vaccines against one or more pathogens
GB201607548D0 (en) * 2016-04-29 2016-06-15 Univ Central Lancashire Solid dosage form
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JOP20190008A1 (ar) 2016-07-26 2019-01-24 Purdue Pharma Lp علاج ومنع اضطرابات النوم
EP3563847B1 (en) * 2016-12-28 2023-09-20 FUJIFILM Toyama Chemical Co., Ltd. Pharmaceutical composition
WO2018155435A1 (ja) * 2017-02-21 2018-08-30 Ｅａファーマ株式会社 顆粒製剤
JP7235193B2 (ja) * 2017-04-26 2023-03-08 大正製薬株式会社 固形組成物
JP7009288B2 (ja) * 2017-05-18 2022-01-25 エルメッド株式会社 湿製錠剤の製造方法及び湿製錠剤の品質向上方法
JP7336187B2 (ja) * 2017-11-30 2023-08-31 日本ケミファ株式会社 多層構造を有する粒子状医薬組成物
WO2019143744A1 (en) 2018-01-16 2019-07-25 Applied Materials, Inc. Metal oxide encapsulated drug compositions and methods of preparing the same
CN111601591A (zh) 2018-01-24 2020-08-28 普渡制药公司 睡眠障碍的治疗和预防
TW201940171A (zh) * 2018-02-08 2019-10-16 景凱生物科技股份有限公司 類鴉片受體拮抗劑之固體劑型用之醫藥劑型
US12371427B2 (en) 2019-01-31 2025-07-29 Purdue Pharma L.P. Polymorphic forms of a substituted-quinoxaline-type bridged-piperidine compound
US12233169B2 (en) 2019-08-27 2025-02-25 Applied Materials, Inc. Vapor phase coating technology for pharmaceutical abuse deterrent formulations
JP2022545279A (ja) 2019-08-27 2022-10-26 アプライド マテリアルズ インコーポレイテッド 医薬品の溶解度制御のための気相コーティング
GB202001237D0 (en) * 2020-01-29 2020-03-11 Sisteks D O O Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product
EP4096791A1 (en) 2020-01-31 2022-12-07 Nanocopoeia LLC Amorphous nilotinib microparticles and uses thereof
IL297776A (en) 2020-04-30 2022-12-01 Nanocopoeia Llc Orally disintegrating tablets containing an amorphous solid dispersion of nalotinib
TWI870622B (zh) 2020-10-02 2025-01-21 美商應用材料股份有限公司 製備氧化矽塗佈藥品的低溫處理
CN112121067A (zh) * 2020-11-16 2020-12-25 深圳科兴药业有限公司 一种婴儿型双歧杆菌微胶囊及其制备方法
JP2023553010A (ja) 2020-12-03 2023-12-20 バテル・メモリアル・インスティテュート 非ウイルス性送達のためのポリマーナノ粒子およびｄｎａナノ構造組成物ならびに方法
EP4320233A4 (en) 2021-04-07 2025-08-13 Battelle Memorial Institute RAPID DESIGN, BUILD, TEST, AND LEARNING TECHNOLOGIES TO IDENTIFY AND USE NON-VIRAL VECTORS
BR112023023702A2 (pt) 2021-05-21 2024-01-30 Purdue Pharma Lp Métodos de tratamento da cistite intersticial/síndrome da dor na bexiga
US12491165B2 (en) 2021-09-30 2025-12-09 Applied Materials, Inc. Low temperature silicon oxide coating for pharmaceutical applications
US20250195417A1 (en) * 2022-03-22 2025-06-19 Daicel Corporation Additive composition for orally disintegrating tablet
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
AU2024364388A1 (en) 2023-10-19 2026-03-19 Purdue Pharma L.P. Sunobinop for use in method of treating alcohol use disorder
WO2025122954A1 (en) 2023-12-08 2025-06-12 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems
CN117860699A (zh) * 2024-01-07 2024-04-12 长沙晶易医药科技股份有限公司 一种细粒剂及其制备方法
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62277322A (ja) 1986-02-13 1987-12-02 Takeda Chem Ind Ltd 安定化された腸溶性抗潰瘍固形組成物
CA1327010C (en) 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
FR2679451B1 (fr) 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
SE9402431D0 (sv) 1994-07-08 1994-07-08 Astra Ab New tablet formulation
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US6096340A (en) 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
EP2263660B1 (en) 1998-05-18 2017-09-27 Takeda Pharmaceutical Company Limited Orally disintegrable tablets
DE69942777D1 (de) 1998-07-28 2010-10-28 Takeda Pharmaceutical Leicht zerfallende feste Zubereitung
EP2266542A3 (en) 1998-10-01 2013-07-31 Elan Pharma International Limited Controlled release nanoparticulate compositions
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
GB0025208D0 (en) 2000-10-13 2000-11-29 Euro Celtique Sa Delayed release pharmaceutical formulations
HU229291B1 (en) * 2001-01-31 2013-10-28 Evonik Roehm Gmbh Multi-particulate form of medicament, comprising at least two differently coated forms of pellet
HUP0401941A3 (en) 2001-07-16 2008-04-28 Astrazeneca Ab Pharmaceutical formulation comprising a proton pomp inhibitor and antacids and process for its preparation
DE10208335A1 (de) 2002-02-27 2003-09-04 Roehm Gmbh Arzneiform und Verfahren zu ihrer Herstellung
AUPS167602A0 (en) 2002-04-12 2002-05-16 F.H. Faulding & Co. Limited An improved modified release preparation
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
JP4493970B2 (ja) 2002-10-16 2010-06-30 武田薬品工業株式会社 持続性製剤
US20040096497A1 (en) 2002-11-19 2004-05-20 Ponder Garratt W. Methods of providing controlled-release pharmaceutical compositions and controlled-release pharmaceutical compositions
MXPA04010956A (es) 2003-01-30 2005-01-25 Roehm Gmbh Forma de dosis farmaceutica y metodo para la produccion de la misma.
WO2005009410A2 (en) 2003-07-17 2005-02-03 Dr. Reddy's Laboratories, Inc. Pharmaceutical compositions having a swellable coating
AU2004275835B2 (en) 2003-09-26 2011-06-23 Alza Corporation Controlled release formulations exhibiting an ascending rate of release
GB0323232D0 (en) * 2003-10-03 2003-11-05 Rolls Royce Plc Electrical machine
EP1750717B1 (en) 2004-02-11 2017-07-19 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
US20050181052A1 (en) 2004-02-17 2005-08-18 Patel Satishkumar A. Lansoprazole microtablets
US20050214371A1 (en) 2004-03-03 2005-09-29 Simona Di Capua Stable pharmaceutical composition comprising an acid labile drug
EP1721604A4 (en) 2004-03-04 2008-04-30 Takeda Pharmaceutical STABLE CAPSULE PREPARATION
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
EP1787640A4 (en) * 2004-04-30 2012-04-11 Astellas Pharma Inc GRAINED PHARMACEUTICAL COMPOSITION WITH TEMPORARY DELIVERY FOR ORAL ADMINISTRATION AND FAST-DECREASING INTRAORAL TABLET WITH THE COMPOSITION
DE102004035936A1 (de) 2004-07-23 2006-03-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
WO2006101536A1 (en) * 2004-11-04 2006-09-28 Akina, Inc. Fast-melting tablets having taste-masking and sustained release properties
WO2006070845A1 (ja) 2004-12-28 2006-07-06 Eisai R & D Management Co., Ltd. 速崩壊性錠剤及びその製造方法
GB0502479D0 (en) 2005-02-07 2005-03-16 Sb Pharmco Inc Novel compositions
FR2885526B1 (fr) 2005-05-13 2007-07-27 Flamel Technologies Sa Medicament oral a base d'inhibiteur de pompe a protons
DE102005024614A1 (de) 2005-05-25 2006-11-30 Röhm Gmbh Verwendung von Polymermischungen zur Herstellung von überzogenen Arzneiformen sowie Arzneiform mit polymerem Mischüberzug
CA2614526A1 (en) 2005-07-11 2006-10-12 Nycomed Danmark Aps Benzimidazole formulation
DE102005032806A1 (de) 2005-07-12 2007-01-18 Röhm Gmbh Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten
WO2007037259A1 (ja) 2005-09-29 2007-04-05 Eisai R & D Management Co., Ltd. 生体内での崩壊性を向上させたパルス製剤
FR2891459B1 (fr) 2005-09-30 2007-12-28 Flamel Technologies Sa Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
EP1813275A1 (en) * 2005-12-20 2007-08-01 Teva Pharmaceutical Industries Ltd Lansoprazole orally disintegrating tablets
CA2633825A1 (en) 2005-12-20 2007-07-05 Teva Pharmaceutical Industries Ltd. Lansoprazole orally disintegrating tablets
JP2009519334A (ja) 2005-12-20 2009-05-14 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール経口崩壊錠剤
US20070141151A1 (en) 2005-12-20 2007-06-21 Silver David I Lansoprazole orally disintegrating tablets
JP5053865B2 (ja) 2005-12-28 2012-10-24 武田薬品工業株式会社 口腔内崩壊性固形製剤の製造法
KR100762847B1 (ko) 2006-01-27 2007-10-04 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
EP1837016A3 (en) 2006-03-08 2008-01-02 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical multiple-unit composition
US20090068263A1 (en) 2006-04-20 2009-03-12 Themis Laboratories Private Limited Multiple unit compositions
JP5826456B2 (ja) 2006-04-26 2015-12-02 アルファファーム ピーティーワイ リミテッド コーティングされていない分離したユニットおよび延長放出マトリクスを含む制御放出配合物
ES2466441T3 (es) 2006-04-28 2014-06-10 Wockhardt Limited Composiciones farmacéuticas que comprenden fármaco antiinflamatorio no esteroideo, acetaminofén e inhibidor de la bomba de protones
US20070292510A1 (en) 2006-06-19 2007-12-20 Hugh Huang Enteric coated particles containing an active ingredient
US20090291136A1 (en) 2006-07-11 2009-11-26 Lek Pharmaceuticals D.D. Multiple Unit Tablets
WO2008014175A2 (en) 2006-07-28 2008-01-31 Dr. Reddy's Laboratories Ltd. Granular pharmaceutical compositions
WO2008025535A1 (en) 2006-08-30 2008-03-06 Jagotec Ag Controlled release oral dosage formulations comprising a core and one or more barrier layers
WO2008081891A1 (ja) * 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤
DE102007009243A1 (de) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets
DE102007009242A1 (de) * 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit magensaftresistenter Wirkstoff-Matix
PT2152250T (pt) 2007-05-07 2019-12-12 Evonik Operations Gmbh Formas farmacêuticas sólidas que compreendem um revestimento entérico com libertação acelerada do fármaco
MY173730A (en) 2008-03-11 2020-02-18 Takeda Pharmaceuticals Co Orally-disintegrating solid preparation
WO2010008569A1 (en) 2008-07-17 2010-01-21 Barr Laboratories, Inc. Orally disintegrating solid pharmaceutical dosage forms comprising delayed-release lansoprazole and methods of making and using the same
JP2014501224A (ja) 2010-12-27 2014-01-20 武田薬品工業株式会社 口腔内崩壊錠

Also Published As

Publication number Publication date
CA2717947C (en) 2020-07-07
TWI441658B (zh) 2014-06-21
AR070863A1 (es) 2010-05-12
MX2010009824A (es) 2010-09-28
KR20100129761A (ko) 2010-12-09
PE20091620A1 (es) 2009-11-12
MA32174B1 (fr) 2011-03-01
CN102026627B (zh) 2016-10-26
EA021792B1 (ru) 2015-09-30
DOP2010000273A (es) 2010-09-30
CR11709A (es) 2010-11-04
WO2009113703A3 (en) 2010-06-17
MY173730A (en) 2020-02-18
US20150037423A1 (en) 2015-02-05
GEP20135845B (en) 2013-06-10
ZA201006679B (en) 2011-11-30
CO6321224A2 (es) 2011-09-20
NZ588407A (en) 2012-07-27
ECSP10010538A (es) 2010-11-30
WO2009113703A2 (en) 2009-09-17
CA2717947A1 (en) 2009-09-17
UY31698A (es) 2009-11-10
US9241910B2 (en) 2016-01-26
CL2009000557A1 (es) 2010-10-01
EP2254556A2 (en) 2010-12-01
PE20141034A1 (es) 2014-09-10
TW200944249A (en) 2009-11-01
AU2009224254A2 (en) 2010-11-18
IL207989A0 (en) 2010-12-30
JP5604304B2 (ja) 2014-10-08
JP2011513204A (ja) 2011-04-28
EA201071054A1 (ru) 2011-04-29
CN104127368A (zh) 2014-11-05
AU2009224254A1 (en) 2009-09-17
US20110091563A1 (en) 2011-04-21
CN102026627A (zh) 2011-04-20

Similar Documents

Publication Publication Date Title
BRPI0909439A2 (pt) preparação sólida de desintegração oral, e, método para suprimir a ruptura de grânulos finos
BR112012009609A2 (pt) método para fabricar uma dispersão sólida, dispersão sólida , preparação farmacêutica e composições
BRPI0912194A2 (pt) Adoçante, método para a preparação e adoçante e aplicações do mesmo
BRPI0817917A2 (pt) Implemento para cuidado oral, e, método para formar um implemento para cuidado oral
BRPI0822825A2 (pt) Implemento para cuidado oral, e, método para formar um implemento para cuidado oral
BRPI0718974A2 (pt) Copolímero, e, método para preparar um copolímero
BRPI0914918A2 (pt) forma de dosagem farmacêutica, e, método para preparar uma forma de dosagem sólida.
BRPI0817923A2 (pt) Implemento para cuidado oral, e, método
BRPI0908092A2 (pt) Edulcorante, método para preparar uma composição edulcorante, e, composição edulcorante
BRPI0909780A2 (pt) Composições e métodos para liberação de fármaco
BRPI0816513A2 (pt) Composição farmacêutica e método para preparar a suspensão sólida
BR112012005422A2 (pt) cápsula de alginato sem costura, e, método para fabricar uma cápsula de alginato sem costura
BRPI0909691A8 (pt) composto, método para preparar um composto, e, composição farmacêutica
BRPI0818883A2 (pt) Sistema intra-uterino, e, método para a formação do mesmo
BRPI0908192A2 (pt) Dispositivo funcional, e, método para produzir um dispositivo funcional
BRPI0912384A2 (pt) composição, e, método para preparar uma composição
BRPI0814381A2 (pt) Dispositivo de segurança, documento de segurança, e, método para fabricar um dispositivo de segurança
BR112012004178A2 (pt) implemento para cuidado oral, e, aparelho para um implemento oral
BR112012005452A2 (pt) cápsula de alginato sem costura, e, método para fabricar uma cápsula de alginato sem costura
BRPI0818680A2 (pt) composição farmacêutica, preparação farmacêutica, e método para preparar um forma de dosagem oral farmacêutica
BRPI1014035A2 (pt) método para contracepção.
BRPI0907646A2 (pt) Composição sólida solúvel efervescente, e, método para limpar um disposotivo dental
BR112012004297A2 (pt) concentrado perolado e método para a fabricação do mesmo.
BR112012016364A2 (pt) "método para fabricar produtos embutidos, embutidos e dispositivo de produção de embutidos"
BRPI1007211A2 (pt) composição farmacêutica oral em uma forma sólida, e, processo para preparar uma composição.

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL