BRPI0910461A2 - fsh recombinante incluindo sialilação alfa 2,3 e alfa 2,6 - Google Patents

fsh recombinante incluindo sialilação alfa 2,3 e alfa 2,6

Info

Publication number: BRPI0910461A2
Authority: BR; Brazil
Prior art keywords: alpha; sialylation; recombinant fsh; fsh including; including alpha
Prior art date: 2008-04-16

Application number

BRPI0910461A

Other languages

English (en)

Inventor

Cottingham Ian

Plaksin Daniel

Boyd White Richard

Original Assignee

Ferring International Center S.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-16

Filing date

2009-04-16

Publication date

2018-03-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0910461(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-04-16 Application filed by Ferring International Center S.A. filed Critical Ferring International Center S.A.

2018-03-27 Publication of BRPI0910461A2 publication Critical patent/BRPI0910461A2/pt

2018-10-16 Publication of BRPI0910461A8 publication Critical patent/BRPI0910461A8/pt

2021-02-23 Publication of BRPI0910461B1 publication Critical patent/BRPI0910461B1/pt

2021-05-25 Publication of BRPI0910461B8 publication Critical patent/BRPI0910461B8/pt

Links

230000009450 sialylation Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Reproductive Health (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Toxicology (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Immunology (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

BRPI0910461A 2008-04-16 2009-04-16 hormônio de estimulação do folículo recombinante, sua composição farmacêutica, seu método de produção e seu uso BRPI0910461B8 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US4542408P	2008-04-16	2008-04-16
US61/045,424		2008-04-16
EP08251528		2008-04-25
EP08251528.9		2008-04-25
PCT/GB2009/000978 WO2009127826A1 (en)	2008-04-16	2009-04-16	Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (4)

Publication Number	Publication Date
BRPI0910461A2 true BRPI0910461A2 (pt)	2018-03-27
BRPI0910461A8 BRPI0910461A8 (pt)	2018-10-16
BRPI0910461B1 BRPI0910461B1 (pt)	2021-02-23
BRPI0910461B8 BRPI0910461B8 (pt)	2021-05-25

Family

ID=39717519

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0910461A BRPI0910461B8 (pt)	2008-04-16	2009-04-16	hormônio de estimulação do folículo recombinante, sua composição farmacêutica, seu método de produção e seu uso

Country Status (29)

Country	Link
US (7)	US8951967B2 (pt)
EP (7)	EP3098234B1 (pt)
JP (7)	JP2011519359A (pt)
KR (5)	KR102108377B1 (pt)
CN (3)	CN105906703A (pt)
AR (1)	AR071479A1 (pt)
AU (5)	AU2009237479B2 (pt)
BR (1)	BRPI0910461B8 (pt)
CA (1)	CA2725257A1 (pt)
CY (1)	CY1115413T1 (pt)
DK (6)	DK3098234T3 (pt)
ES (5)	ES2989729T3 (pt)
FI (4)	FI4015527T3 (pt)
FR (3)	FR17C1020I2 (pt)
HR (5)	HRP20241187T1 (pt)
HU (9)	HUE033830T2 (pt)
IL (2)	IL208538A (pt)
LT (8)	LT3045471T (pt)
MX (3)	MX348622B (pt)
NO (4)	NO2017025I1 (pt)
NZ (1)	NZ588381A (pt)
PL (6)	PL2808340T3 (pt)
PT (6)	PT3144318T (pt)
RU (3)	RU2682270C2 (pt)
SA (1)	SA109300228B1 (pt)
SI (6)	SI2808340T1 (pt)
TW (1)	TWI488640B (pt)
WO (1)	WO2009127826A1 (pt)
ZA (1)	ZA201007373B (pt)

Families Citing this family (29)

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TWI488640B (zh)	2008-04-16	2015-06-21	菲瑞茵國際中心股份有限公司	藥學製劑
TWI532495B (zh)	2009-10-05	2016-05-11	菲瑞茵國際中心股份有限公司	藥學製劑
EP2417982A1 (en)	2010-07-30	2012-02-15	Ferring B.V.	Stabilization of gonadotropins
WO2012016576A1 (en) *	2010-08-04	2012-02-09	Glycotope Gmbh	Improved recombinant human follicle-stimulating hormone
US9320778B2 (en)	2010-09-29	2016-04-26	Ferring B.V.	Method for controlled ovarian stimulation with combined FSH and hCG
CN103154243A (zh)	2010-10-15	2013-06-12	日本化学研究株式会社	糖链的非还原末端为甘露糖残基的糖蛋白的制造方法
CA3163525A1 (en)	2011-03-31	2012-10-04	Ferring Bv.	Pharmaceutical preparation
WO2012168680A1 (en)	2011-06-06	2012-12-13	Ferring B.V.	Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) *	2011-08-08	2017-03-15	Ferring Bv	مركب لتحفيز مسيطر عليه للمبيض
AU2012340501A1 (en) *	2011-12-19	2013-07-11	Grifols, S.A.	Compositions, methods, and kits for preparing sialylated recombinant proteins
JP6279466B2 (ja) *	2012-04-27	2018-02-14	Ｊｃｒファーマ株式会社	新規な発現ベクター
EP2824176A1 (en) *	2013-07-11	2015-01-14	Siamed'xpress	Methods for producing sialylated therapeutic proteins
JP6652334B2 (ja) *	2014-05-31	2020-02-19	Ｊｃｒファーマ株式会社	ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地
JP2018500934A (ja) *	2014-12-22	2018-01-18	エフ．ホフマン−ラロシュアーゲーＦ．Ｈｏｆｆｍａｎｎ−ＬａＲｏｃｈｅＡｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ	Ｃｍｐ依存性シアリダーゼ活性
HUE054300T2 (hu)	2015-04-17	2021-08-30	Ferring Bv	FSH-t tartalmazó, meddõség kezelésére szolgáló készítmény
US10906953B2 (en)	2015-06-26	2021-02-02	Ferring B.V.	Methods of purification and/or viral inactivation
EP3205719A1 (en) *	2016-02-15	2017-08-16	CEVEC Pharmaceuticals GmbH	Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins
GB201603280D0 (en)	2016-02-24	2016-04-13	Ferring Bv	Stable liquid gonadotropin formulation
EP3382014A1 (en)	2017-03-29	2018-10-03	CEVEC Pharmaceuticals GmbH	Recombinant glycoproteins with reduced antennary fucosylation
EP3441471A1 (en)	2017-08-08	2019-02-13	CEVEC Pharmaceuticals GmbH	Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
SI3973982T1 (sl)	2017-09-01	2024-10-30	Ferring B. V.	Sestavek za nadzorovano stimulacijo jajčnikov
WO2019211153A1 (en)	2018-04-30	2019-11-07	Ferring B.V.	Composition for controlled ovarian stimulation
TWI846743B (zh)	2018-10-17	2024-07-01	荷蘭商菲林公司	用於控制性卵巢刺激之組成物及方法
US20220380785A1 (en) *	2019-11-01	2022-12-01	The University Of British Columbia	Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh)	2020-12-09	2022-10-01	荷蘭商菲林公司	用於受控的卵巢刺激之組成物及方法
CN118922201A (zh)	2022-04-01	2024-11-08	辉凌公司	治疗不育症的混合方案
KR20250016113A (ko)	2022-05-26	2025-02-03	훼링 비.브이.	남성 불임 치료를 위한 조성물 및 방법
MA71382A (fr)	2022-07-08	2025-04-30	Ferring B.V.	Compositions et procédés d'insémination intra-utérine (iiu)
KR20260041113A (ko)	2023-07-20	2026-03-26	훼링 비.브이.	서방형의 약물-로딩된 마이크로입자

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CA2372714A1 (en)	1999-05-07	2000-11-16	Stephen Franks	The use of luteinizing hormone in the induction of pauci-or unifolliculogenesis
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EA008220B1 (ru)	2001-10-29	2007-04-27	Круселл Холланд Б.В.	Композиция, включающая эритропоэтинподобные молекулы, и способы ее применения
ATE384785T1 (de)	2001-12-07	2008-02-15	Crucell Holland Bv	Herstellung von viren, virusisolaten, und impfstoffen
US20040248784A1 (en)	2003-06-03	2004-12-09	Marco Filicori	Unitary combinations of FSH and hCG
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ATE476666T1 (de)	2004-02-04	2010-08-15	Centre Nat Rech Scient	Verfahren zur identifizierung von glykoformspezifischen antikörpern
CA2557725C (en)	2004-02-13	2015-06-30	Glycotope Gmbh	Highly active glycoproteins-process conditions and an efficient method for their production
TWI488640B (zh)	2008-04-16	2015-06-21	菲瑞茵國際中心股份有限公司	藥學製劑
TWI532495B (zh)	2009-10-05	2016-05-11	菲瑞茵國際中心股份有限公司	藥學製劑
EP2417982A1 (en)	2010-07-30	2012-02-15	Ferring B.V.	Stabilization of gonadotropins
US8790322B2 (en)	2010-08-03	2014-07-29	King Saud University	Stoma coat
WO2012016576A1 (en) *	2010-08-04	2012-02-09	Glycotope Gmbh	Improved recombinant human follicle-stimulating hormone
US9320778B2 (en)	2010-09-29	2016-04-26	Ferring B.V.	Method for controlled ovarian stimulation with combined FSH and hCG
CA3163525A1 (en)	2011-03-31	2012-10-04	Ferring Bv.	Pharmaceutical preparation
WO2012168680A1 (en)	2011-06-06	2012-12-13	Ferring B.V.	Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar)	2011-08-08	2017-03-15	Ferring Bv	مركب لتحفيز مسيطر عليه للمبيض
AR100132A1 (es)	2014-04-18	2016-09-14	Glycotope Gmbh	Un método para hiperestimulación ovárica controlada para estimular el desarrollo de múltiples folículos ováricos en un sujeto femenino

2009
- 2009-04-15 TW TW098112483A patent/TWI488640B/zh active
- 2009-04-16 CN CN201510933827.2A patent/CN105906703A/zh active Pending
- 2009-04-16 AR ARP090101333A patent/AR071479A1/es not_active Application Discontinuation
- 2009-04-16 MX MX2014011348A patent/MX348622B/es unknown
- 2009-04-16 CA CA2725257A patent/CA2725257A1/en active Pending
- 2009-04-16 RU RU2014141994A patent/RU2682270C2/ru active
- 2009-04-16 LT LTEP16158141.8T patent/LT3045471T/lt unknown
- 2009-04-16 PL PL14178729T patent/PL2808340T3/pl unknown
- 2009-04-16 RU RU2010141908/10A patent/RU2537268C2/ru active
- 2009-04-16 MX MX2010011343A patent/MX2010011343A/es active IP Right Grant
- 2009-04-16 US US12/988,218 patent/US8951967B2/en active Active
- 2009-04-16 EP EP16179121.5A patent/EP3098234B1/en active Active
- 2009-04-16 KR KR1020197022294A patent/KR102108377B1/ko not_active Expired - Fee Related
- 2009-04-16 SI SI200931547A patent/SI2808340T1/sl unknown
- 2009-04-16 SI SI200932094T patent/SI3144318T1/sl unknown
- 2009-04-16 EP EP16194925.0A patent/EP3144318B1/en active Active
- 2009-04-16 ES ES16179121T patent/ES2989729T3/es active Active
- 2009-04-16 WO PCT/GB2009/000978 patent/WO2009127826A1/en not_active Ceased
- 2009-04-16 CN CN201510933782.9A patent/CN105906702A/zh active Pending
- 2009-04-16 PL PL16158141T patent/PL3045471T3/pl unknown
- 2009-04-16 AU AU2009237479A patent/AU2009237479B2/en active Active
- 2009-04-16 HU HUE16158141A patent/HUE033830T2/en unknown
- 2009-04-16 PT PT161949250T patent/PT3144318T/pt unknown
- 2009-04-16 PT PT141787291T patent/PT2808340T/pt unknown
- 2009-04-16 HU HUE21212873A patent/HUE071059T2/hu unknown
- 2009-04-16 EP EP21212873.0A patent/EP4015527B1/en active Active
- 2009-04-16 BR BRPI0910461A patent/BRPI0910461B8/pt active IP Right Grant
- 2009-04-16 PL PL09733497T patent/PL2268666T3/pl unknown
- 2009-04-16 KR KR1020167012148A patent/KR20160056960A/ko not_active Ceased
- 2009-04-16 ES ES21212873T patent/ES3023526T3/es active Active
- 2009-04-16 HR HRP20241187TT patent/HRP20241187T1/hr unknown
- 2009-04-16 DK DK16179121.5T patent/DK3098234T3/da active
- 2009-04-16 LT LTEP14178729.1T patent/LT2808340T/lt unknown
- 2009-04-16 PL PL16179121.5T patent/PL3098234T3/pl unknown
- 2009-04-16 FI FIEP21212873.0T patent/FI4015527T3/fi active
- 2009-04-16 MX MX2017007881A patent/MX355457B/es unknown
- 2009-04-16 ES ES16158141.8T patent/ES2629392T3/es active Active
- 2009-04-16 PT PT161581418T patent/PT3045471T/pt unknown
- 2009-04-16 EP EP14178729.1A patent/EP2808340B1/en not_active Revoked
- 2009-04-16 HR HRP20250313TT patent/HRP20250313T1/hr unknown
- 2009-04-16 LT LTEP21212873.0T patent/LT4015527T/lt unknown
- 2009-04-16 PT PT97334973T patent/PT2268666E/pt unknown
- 2009-04-16 EP EP16158141.8A patent/EP3045471B1/en not_active Revoked
- 2009-04-16 HU HUE14178729A patent/HUE030652T4/en unknown
- 2009-04-16 DK DK14178729.1T patent/DK2808340T3/en active
- 2009-04-16 FI FIEP16179121.5T patent/FI3098234T3/fi active
- 2009-04-16 PT PT212128730T patent/PT4015527T/pt unknown
- 2009-04-16 KR KR1020107025581A patent/KR101622944B1/ko active Active
- 2009-04-16 LT LTEP16179121.5T patent/LT3098234T/lt unknown
- 2009-04-16 PL PL16194925T patent/PL3144318T3/pl unknown
- 2009-04-16 PT PT161791215T patent/PT3098234T/pt unknown
- 2009-04-16 SI SI200931670A patent/SI3045471T1/sl unknown
- 2009-04-16 KR KR1020187023820A patent/KR20180095140A/ko not_active Ceased
- 2009-04-16 KR KR1020177026920A patent/KR20170110741A/ko not_active Ceased
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EP2268666A1 (en)	2011-01-05
SI3045471T1 (sl)	2017-07-31
KR20110005863A (ko)	2011-01-19
LT2808340T (lt)	2016-11-10
HRP20170958T1 (hr)	2017-09-22
PL3098234T3 (pl)	2025-01-07
JP2011519359A (ja)	2011-07-07
HUS2500029I1 (hu)	2025-07-28
FI3098234T3 (fi)	2024-10-31
EP3045471B1 (en)	2017-03-29
LT3098234T (lt)	2024-09-10
RU2745557C1 (ru)	2021-03-29
US20110105398A1 (en)	2011-05-05
JP6762916B2 (ja)	2020-09-30
CA2725257A1 (en)	2009-10-22
DK4015527T3 (da)	2025-04-14
SI3144318T1 (sl)	2020-12-31
ES2629392T3 (es)	2017-08-09
SI4015527T1 (sl)	2025-05-30
AU2017204258A1 (en)	2017-07-20
US9546204B2 (en)	2017-01-17
FR25C1025I1 (fr)	2025-09-19
EP3098234B1 (en)	2024-07-31
NO2025006I1 (no)	2025-01-16
HUE068565T2 (hu)	2025-01-28
US11952407B2 (en)	2024-04-09
AU2014203277C1 (en)	2017-07-27
MX2010011343A (es)	2011-01-20
PL4015527T3 (pl)	2025-05-26
CY1115413T1 (el)	2017-01-04
NO2017025I1 (no)	2017-06-06
JP2017060476A (ja)	2017-03-30
HUS1700025I1 (hu)	2017-06-28
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WO2009127826A1 (en)	2009-10-22
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NO2025032I1 (no)	2025-07-14
EP3144318A1 (en)	2017-03-22
RU2745557C3 (ru)	2021-12-10
SI2808340T1 (sl)	2016-12-30
SI2268666T1 (sl)	2014-07-31
PT2808340T (pt)	2016-11-21
RU2537268C2 (ru)	2014-12-27
BRPI0910461A8 (pt)	2018-10-16
KR101622944B1 (ko)	2016-05-23
PL3045471T3 (pl)	2017-10-31
EP3045471A1 (en)	2016-07-20
LT3045471T (lt)	2017-07-10
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CN105906703A (zh)	2016-08-31
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JP7316905B2 (ja)	2023-07-28
AU2017225020B2 (en)	2019-11-14
LTPA2017018I1 (lt)	2017-06-26
ZA201007373B (en)	2011-06-29
FR17C1020I2 (fr)	2020-04-10
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TWI488640B (zh)	2015-06-21
BRPI0910461B8 (pt)	2021-05-25
CN102066414A (zh)	2011-05-18
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NZ588381A (en)	2012-05-25
MX355457B (es)	2018-04-19
PT2268666E (pt)	2014-06-25
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DK3045471T3 (en)	2017-06-26
EP2808340B1 (en)	2016-08-17
FI4015527T3 (fi)	2025-04-29
LTPA2025525I1 (pt)	2025-07-25
EP4015527A1 (en)	2022-06-22
EP2722339A1 (en)	2014-04-23

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