BRPI0918959A2 - proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária - Google Patents

proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária

Info

Publication number: BRPI0918959A2
Authority: BR; Brazil
Prior art keywords: platelet aggregation; recombinant proteins; hemostatic activity; inducing platelet; inducing
Prior art date: 2008-09-24

Application number

BRPI0918959A

Other languages

English (en)

Inventor

David Vandroux

Edourd Prost

Emmanuel De Maistre

Original Assignee

Ct Hospitalier Universitaire De Dijon

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-09-24

Filing date

2009-09-22

Publication date

2015-12-01

2009-09-22 Application filed by Ct Hospitalier Universitaire De Dijon filed Critical Ct Hospitalier Universitaire De Dijon

2015-12-01 Publication of BRPI0918959A2 publication Critical patent/BRPI0918959A2/pt

2021-07-27 Publication of BRPI0918959B1 publication Critical patent/BRPI0918959B1/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Toxicology (AREA)
Hematology (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Cosmetics (AREA)

BRPI0918959-9A 2008-09-24 2009-09-22 Proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária BRPI0918959B1 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0856423A FR2936247B1 (fr)	2008-09-24	2008-09-24	Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.
FR0856423		2008-09-24
PCT/EP2009/062271 WO2010034718A1 (fr)	2008-09-24	2009-09-22	Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquett aire

Publications (2)

Publication Number	Publication Date
BRPI0918959A2 true BRPI0918959A2 (pt)	2015-12-01
BRPI0918959B1 BRPI0918959B1 (pt)	2021-07-27

Family

ID=40613031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0918959-9A BRPI0918959B1 (pt)	2008-09-24	2009-09-22	Proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária

Country Status (14)

Country	Link
US (2)	US8557774B2 (pt)
EP (1)	EP2337796B1 (pt)
JP (1)	JP5675620B2 (pt)
KR (1)	KR101700970B1 (pt)
CN (1)	CN102224167B (pt)
AU (1)	AU2009295917B2 (pt)
BR (1)	BRPI0918959B1 (pt)
CA (1)	CA2738209C (pt)
DK (1)	DK2337796T3 (pt)
ES (1)	ES2419657T3 (pt)
FR (1)	FR2936247B1 (pt)
IL (1)	IL211740A (pt)
WO (1)	WO2010034718A1 (pt)
ZA (1)	ZA201101989B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUE044239T2 (hu)	2008-03-27	2019-10-28	Purdue Research Foundation	Kollagén-kötõ szintetikus peptidoglikánok, elõállításuk és alkalmazási eljárásaik
FR2936247B1 (fr) *	2008-09-24	2010-10-22	Ct Hospitalier Universitaire De Dijon	Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.
WO2010129547A1 (en) *	2009-05-04	2010-11-11	Purdue Research Foundation	Collagen-binding synthetic peptidoglycans for wound healing
AU2011270862B2 (en) *	2010-06-23	2017-05-11	Purdue Research Foundation	Collagen-binding synthetic peptidoglycans for use in vascular intervention
JP5747493B2 (ja) *	2010-12-13	2015-07-15	Jnc株式会社	血小板放出促進剤および血小板放出促進方法
US9217016B2 (en)	2011-05-24	2015-12-22	Symic Ip, Llc	Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
FR2997083B1 (fr)	2012-10-19	2014-12-12	Nvh Medicinal	Proteines recombinantes derivees du collagene a activite de liaison au facteur willebrand
WO2014144969A1 (en)	2013-03-15	2014-09-18	Purdue Research Foundation	Extracellular matrix-binding synthetic peptidoglycans
FR3014319B1 (fr) *	2013-12-11	2016-12-09	Nvh Medicinal	Preparations injectables a base de collagenes capables de controler les saignements et/ou de se substituer a des plaquettes dans le cas de syndromes hemorragiques
WO2015164822A1 (en)	2014-04-25	2015-10-29	Purdue Research Foundation	Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
CN109311956A (zh)	2015-08-25	2019-02-05	伊斯迪德股份公司	诱导组织形成的化合物及其应用
KR20200026263A (ko)	2017-07-07	2020-03-10	시믹 아이피, 엘엘씨	합성 생체접합체
CN108503694B (zh) *	2017-07-10	2019-12-24	昆明医科大学第一附属医院	一种促血小板聚集的多肽8496
CN108503692B (zh) *	2017-07-10	2019-12-31	昆明医科大学第一附属医院	一种促血小板聚集的多肽pep1
CN108570095B (zh) *	2017-07-10	2019-12-31	昆明医科大学第一附属医院	一种促血小板聚集的多肽site2
CN108503693B (zh) *	2017-07-10	2019-12-31	昆明医科大学第一附属医院	一种促血小板聚集的多肽km17
CN107653244B (zh) *	2017-11-30	2020-06-02	海默斯（重庆）医学生物技术有限公司	一种止血蛋白及其制备方法和应用
CN109456989B (zh) *	2018-10-31	2022-03-29	陕西慧康生物科技有限责任公司	一种提高毕赤酵母分泌表达的载体的构建方法
FR3112942A1 (fr)	2020-08-03	2022-02-04	Nvh Medicinal	Ligands protéiques immunomodulateurs dérivés du collagène utilisables par voie injectable
CN118359701B (zh) *	2024-04-26	2025-03-28	河北纳科生物科技有限公司	一种重组人ii型胶原蛋白及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2399371A1 (en) *	1999-11-12	2001-05-17	Fibrogen, Inc.	Animal collagens and gelatins
RU2002112750A (ru) *	1999-11-12	2004-01-27	Файброджен, Инк. (Us)	Коллагены и желатины животного происхождения
US20040151731A1 (en) *	2003-02-04	2004-08-05	Jicha Douglas L.	Methods and compositions involving T-lymphocyte reactivity with collagen in aortic tissue of abdominal aortic aneurysm patients
ATE465747T1 (de) *	2003-03-28	2010-05-15	Fujifilm Mfg Europe Bv	Rgd-angereicherte gelatineähnliche proteine zur verhinderung der blutplättchenaggregation
JP2005058499A (ja) *	2003-08-13	2005-03-10	Masao Tanihara	生体材料
FR2936247B1 (fr) *	2008-09-24	2010-10-22	Ct Hospitalier Universitaire De Dijon	Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire.

2008
- 2008-09-24 FR FR0856423A patent/FR2936247B1/fr not_active Expired - Fee Related
2009
- 2009-09-22 ES ES09736873T patent/ES2419657T3/es active Active
- 2009-09-22 CA CA2738209A patent/CA2738209C/en active Active
- 2009-09-22 WO PCT/EP2009/062271 patent/WO2010034718A1/fr not_active Ceased
- 2009-09-22 US US13/120,838 patent/US8557774B2/en not_active Expired - Fee Related
- 2009-09-22 EP EP09736873.2A patent/EP2337796B1/fr active Active
- 2009-09-22 DK DK09736873.2T patent/DK2337796T3/da active
- 2009-09-22 BR BRPI0918959-9A patent/BRPI0918959B1/pt not_active IP Right Cessation
- 2009-09-22 JP JP2011528308A patent/JP5675620B2/ja not_active Expired - Fee Related
- 2009-09-22 KR KR1020117006538A patent/KR101700970B1/ko not_active Expired - Fee Related
- 2009-09-22 AU AU2009295917A patent/AU2009295917B2/en not_active Ceased
- 2009-09-22 CN CN200980146800.1A patent/CN102224167B/zh not_active Expired - Fee Related
2011
- 2011-03-15 IL IL211740A patent/IL211740A/en active IP Right Grant
- 2011-03-16 ZA ZA2011/01989A patent/ZA201101989B/en unknown
2013
- 2013-06-07 US US13/913,306 patent/US9115183B2/en active Active

Also Published As

Publication number	Publication date
FR2936247A1 (fr)	2010-03-26
AU2009295917A1 (en)	2010-04-01
FR2936247B1 (fr)	2010-10-22
US8557774B2 (en)	2013-10-15
CA2738209A1 (en)	2010-04-01
EP2337796A1 (fr)	2011-06-29
US9115183B2 (en)	2015-08-25
JP2012503481A (ja)	2012-02-09
CN102224167B (zh)	2014-04-02
WO2010034718A1 (fr)	2010-04-01
ES2419657T3 (es)	2013-08-21
AU2009295917B2 (en)	2014-02-06
CA2738209C (en)	2018-02-20
CN102224167A (zh)	2011-10-19
JP5675620B2 (ja)	2015-02-25
IL211740A0 (en)	2011-06-30
BRPI0918959B1 (pt)	2021-07-27
US20110207669A1 (en)	2011-08-25
KR101700970B1 (ko)	2017-01-31
US20130260456A1 (en)	2013-10-03
ZA201101989B (en)	2012-01-25
IL211740A (en)	2014-12-31
EP2337796B1 (fr)	2013-04-17
DK2337796T3 (da)	2013-07-15
WO2010034718A8 (fr)	2010-12-23
KR20110069020A (ko)	2011-06-22

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-24	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2018-10-02	B06T	Formal requirements before examination [chapter 6.20 patent gazette]
2019-06-25	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2020-12-15	B06G	Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
2021-06-08	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2021-07-27	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/09/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.
2025-07-22	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 16A ANUIDADE.
2025-11-18	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2846 DE 22-07-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0918959A2 (pt)	2015-12-01	proteínas recombinantes tendo atividade hemostática e capazes de induzir agregação plaquetária
EP3711771C0 (en)	2025-09-03	ATTENTION OF TISSUE DAMAGE AND FIBROSIS VIA THE BETA-BINDING PROTEIN (LTBP4) OF A LATENT TRANSFORMATION GROWTH FACTOR
EP2408921A4 (en)	2012-10-10	MODIFICATION OF CXCR4 USING MODIFIED ZINC FINGER PROTEINS
IL264649B (en)	2021-01-31	Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)
EP2502939A4 (en)	2013-07-10	UNNATURAL COLLAGEN ARTICLE PROTEIN AND ITS USE
BRPI0906501A2 (pt)	2017-06-13	composição compreendendo proteína e gordura dispersas
EA201171494A1 (ru)	2012-06-29	Миметики белка smac
HRP20260055T1 (hr)	2026-03-13	Nehemolitički llo fuzioni proteini i njihova upotreba
EP2638534A4 (en)	2016-04-06	Cognitive increase in the presence of distraction and / or interruption
BR112012011464A2 (pt)	2015-09-15	proteínas encapsuladas de óleo modificadas e seu uso
BRPI1009413A2 (pt)	2016-03-01	emulsões e adesivos contendo proteína e produção e uso dos mesmos
EP2575857A4 (en)	2014-01-01	INNOVATIVE DETECTION OF THERAPEUTIC, DIAGNOSTIC AND ANTIBODY COMPOSITIONS ASSOCIATED WITH PROTEIN FRAGMENTS OF LYSYL TRNA SYNTHETASES
ATE466537T1 (de)	2010-05-15	System zur spaltung und entfernung von proteinösem gewebe
EP2512221A4 (en)	2013-10-09	COMBINED USE OF CRY1DA AND CRY1FA PROTEINS FOR INSECTROSIVE MANAGEMENT
PT2651975T (pt)	2017-11-14	Anticorpo monoclonal humano com especificidade para a proteína do vírus do dengue de seroptipo 1 e suas utilizações
BR112012031416A2 (pt)	2016-11-08	solução aceleradora e uso de uma solução aceleradora
IL232073A0 (en)	2014-05-28	Recombinant human naglu protein and its uses
BRPI0912768A2 (pt)	2016-05-17	vacinas de poliproteínas recombinante para o tratamento e diagnóstico de leishmaniose
IL208979B (en)	2018-02-28	Humanized antibodies against human interferon-alpha
BRPI1007940A2 (pt)	2016-07-26	"peptídeos relacionados ao colágeno e usos dos mesmos e substratos de espumas hemostáticas"
EP2068941A4 (en)	2009-09-30	IMPROVING CONCENTRATIONS OR ACTIVITY OF ARGINASE
IL232645B (en)	2021-01-31	Recombinant proteins and their therapeutic uses
BR112012030941A2 (pt)	2017-06-06	proteína de fusão tendo atividade de fator vii
FR2917629B1 (fr)	2009-09-11	Utilisation cosmetique de proteines de type apolipoproteine d
SI2170877T1 (sl)	2013-03-29	Substutuirani (oksazolidinon-5-il-metil)-2-tiofen-karboksamidi in njihova uporaba na področju koagulacije krvi