BRPI0919426A2 - métodos melhorado de exposição de rna - Google Patents

métodos melhorado de exposição de rna

Info

Publication number
BRPI0919426A2
BRPI0919426A2 BRPI0919426A BRPI0919426A BRPI0919426A2 BR PI0919426 A2 BRPI0919426 A2 BR PI0919426A2 BR PI0919426 A BRPI0919426 A BR PI0919426A BR PI0919426 A BRPI0919426 A BR PI0919426A BR PI0919426 A2 BRPI0919426 A2 BR PI0919426A2
Authority
BR
Brazil
Prior art keywords
exposure methods
enhanced rna
rna exposure
enhanced
methods
Prior art date
Application number
BRPI0919426A
Other languages
English (en)
Inventor
Chungming Hsieh
John E Memmott
Yuliya A Kutskovva
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0919426A2 publication Critical patent/BRPI0919426A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0919426A 2008-09-30 2009-09-30 métodos melhorado de exposição de rna BRPI0919426A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10147108P 2008-09-30 2008-09-30
PCT/US2009/059057 WO2010039850A1 (en) 2008-09-30 2009-09-30 Improved method of rna display

Publications (1)

Publication Number Publication Date
BRPI0919426A2 true BRPI0919426A2 (pt) 2015-12-15

Family

ID=42073857

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919426A BRPI0919426A2 (pt) 2008-09-30 2009-09-30 métodos melhorado de exposição de rna

Country Status (16)

Country Link
US (1) US8916504B2 (pt)
EP (1) EP2342562B1 (pt)
JP (1) JP5968624B2 (pt)
KR (1) KR20110076906A (pt)
CN (1) CN102227638B (pt)
AU (1) AU2009298499A1 (pt)
BR (1) BRPI0919426A2 (pt)
CA (1) CA2737035A1 (pt)
ES (1) ES2434850T3 (pt)
IL (1) IL211551A (pt)
MX (1) MX2011003381A (pt)
NZ (1) NZ591544A (pt)
RU (1) RU2011117210A (pt)
TW (1) TW201024731A (pt)
WO (1) WO2010039850A1 (pt)
ZA (1) ZA201102120B (pt)

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US10370651B2 (en) * 2013-06-28 2019-08-06 X-Body, Inc. Target antigen discovery, phenotypic screens and use thereof for identification of target cell specific target epitopes
JP6814634B2 (ja) 2014-02-05 2021-01-20 モレキュラー テンプレーツ, インク.Molecular Templates, Inc. リボ毒性の一時的な減少に基づき、細胞毒性組換えポリペプチドをスクリーニングし、選択し、同定する方法
US10093733B2 (en) 2014-12-11 2018-10-09 Abbvie Inc. LRP-8 binding dual variable domain immunoglobulin proteins
EP3549606A1 (en) * 2015-05-28 2019-10-09 Bio-rad Laboratories, Inc. Affinity ligands and methods relating thereto
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗vegf、pdgf及/或其受體之結合蛋白
KR20190014525A (ko) 2016-05-27 2019-02-12 애브비 바이오테라퓨틱스 인크. 면역 조절 단백질과 종양 항원을 결합하는 이중특이적 결합 단백질
CN111511768B (zh) * 2017-11-20 2024-03-26 南特生物科学公司 mRNA展示抗体文库和方法
CN113710801B (zh) * 2019-02-22 2024-07-09 爱普思隆分子进化工程株式会社 一种使用cDNA展示的新型免疫PCR方法
CN114585736B (zh) * 2020-10-27 2023-05-02 北京寻因生物科技有限公司 一种嘌呤霉素连接子及其在体外核酸展示肽合成中的应用
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WO2026025103A1 (en) * 2024-07-26 2026-01-29 The Children's Medical Center Corporation Methods of modulating growth factor activity
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Also Published As

Publication number Publication date
CA2737035A1 (en) 2010-04-08
EP2342562A1 (en) 2011-07-13
MX2011003381A (es) 2011-04-21
US20100105569A1 (en) 2010-04-29
EP2342562B1 (en) 2013-09-18
KR20110076906A (ko) 2011-07-06
ES2434850T3 (es) 2013-12-17
JP5968624B2 (ja) 2016-08-10
NZ591544A (en) 2013-01-25
US8916504B2 (en) 2014-12-23
AU2009298499A1 (en) 2010-04-08
IL211551A (en) 2014-06-30
EP2342562A4 (en) 2012-03-21
ZA201102120B (en) 2011-12-28
TW201024731A (en) 2010-07-01
WO2010039850A1 (en) 2010-04-08
CN102227638A (zh) 2011-10-26
RU2011117210A (ru) 2012-11-10
JP2012504415A (ja) 2012-02-23
HK1159250A1 (en) 2012-07-27
CN102227638B (zh) 2015-05-20
IL211551A0 (en) 2011-05-31

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: ABBVIE INC. (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2386 DE 27-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.