BRPI0417302A - inibidores de receptores de fator de crescimento endotelial vascular do tipo 2 - Google Patents

inibidores de receptores de fator de crescimento endotelial vascular do tipo 2

Info

Publication number
BRPI0417302A
BRPI0417302A BRPI0417302-3A BRPI0417302A BRPI0417302A BR PI0417302 A BRPI0417302 A BR PI0417302A BR PI0417302 A BRPI0417302 A BR PI0417302A BR PI0417302 A BRPI0417302 A BR PI0417302A
Authority
BR
Brazil
Prior art keywords
growth factor
vascular endothelial
factor receptor
endothelial growth
type
Prior art date
Application number
BRPI0417302-3A
Other languages
English (en)
Inventor
Yan Chen
Elena Getmanova
Martin C Wright
Al Harris
Ai Ching Lim
Jochim Gokemeijer
Original Assignee
Compound Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compound Therapeutics Inc filed Critical Compound Therapeutics Inc
Publication of BRPI0417302A publication Critical patent/BRPI0417302A/pt

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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • C07K2318/00—Antibody mimetics or scaffolds
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

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Abstract

"INIBIDORES DE RECEPTORES DE FATOR DE CRESCIMENTO ENDOTELIAL VASCULAR DO TIPO 2". A presente invenção se refere a novos polipeptídeos de ligação a receptor de fator de crescimento endotelial vascular (VEGFR) e a processos para uso destes polipeptídeos para inibir atividades biológicas mediadas por fatores de crescimento endotelial vascular (VEGFs ). A presente invenção também fornece vários melhoramentos com relação aos polipeptídeos de ligação de domínio único.
BRPI0417302-3A 2003-12-05 2004-12-06 inibidores de receptores de fator de crescimento endotelial vascular do tipo 2 BRPI0417302A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52788603P 2003-12-05 2003-12-05
PCT/US2004/040885 WO2005056764A2 (en) 2003-12-05 2004-12-06 Inhibitors of type 2 vascular endothelial growth factor receptors

Publications (1)

Publication Number Publication Date
BRPI0417302A true BRPI0417302A (pt) 2007-03-06

Family

ID=34676785

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417302-3A BRPI0417302A (pt) 2003-12-05 2004-12-06 inibidores de receptores de fator de crescimento endotelial vascular do tipo 2

Country Status (14)

Country Link
US (7) US7858739B2 (pt)
EP (1) EP1711196A4 (pt)
JP (2) JP5006651B2 (pt)
KR (1) KR20060129246A (pt)
CN (1) CN1946417A (pt)
AU (1) AU2004296376B2 (pt)
BR (1) BRPI0417302A (pt)
CA (1) CA2552435A1 (pt)
IL (1) IL176135A0 (pt)
MX (1) MXPA06006406A (pt)
RU (1) RU2402567C2 (pt)
SG (1) SG149004A1 (pt)
TW (1) TW200531979A (pt)
WO (1) WO2005056764A2 (pt)

Families Citing this family (215)

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WO1998056915A2 (en) 1997-06-12 1998-12-17 Research Corporation Technologies, Inc. Artificial antibody polypeptides
ATE354675T1 (de) 1998-12-02 2007-03-15 Adnexus Therapeutics Inc Dna-protein fusionen sowie anwendungen derselben
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
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