BRPI0919973A2 - derivados de arilpiridona antivirais heterocíclicos - Google Patents

derivados de arilpiridona antivirais heterocíclicos

Info

Publication number
BRPI0919973A2
BRPI0919973A2 BRPI0919973A BRPI0919973A BRPI0919973A2 BR PI0919973 A2 BRPI0919973 A2 BR PI0919973A2 BR PI0919973 A BRPI0919973 A BR PI0919973A BR PI0919973 A BRPI0919973 A BR PI0919973A BR PI0919973 A2 BRPI0919973 A2 BR PI0919973A2
Authority
BR
Brazil
Prior art keywords
arylpyridone
derivatives
heterocyclic antiviral
antiviral
heterocyclic
Prior art date
Application number
BRPI0919973A
Other languages
English (en)
Inventor
Alfred Sui-Ting Lui
Francisco Xavier Talamas
Jim Li
Kristen Lynn Mccaleb
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0919973A2 publication Critical patent/BRPI0919973A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
BRPI0919973A 2008-10-30 2009-10-21 derivados de arilpiridona antivirais heterocíclicos BRPI0919973A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19794308P 2008-10-30 2008-10-30
PCT/EP2009/063811 WO2010049331A1 (en) 2008-10-30 2009-10-21 Heterocyclic antiviral arylpyridone derivatives

Publications (1)

Publication Number Publication Date
BRPI0919973A2 true BRPI0919973A2 (pt) 2015-12-08

Family

ID=41509812

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919973A BRPI0919973A2 (pt) 2008-10-30 2009-10-21 derivados de arilpiridona antivirais heterocíclicos

Country Status (15)

Country Link
US (1) US8232271B2 (pt)
EP (1) EP2350007A1 (pt)
JP (1) JP2012506888A (pt)
KR (1) KR20110074941A (pt)
CN (1) CN102186823A (pt)
AR (1) AR074066A1 (pt)
AU (1) AU2009309813A1 (pt)
BR (1) BRPI0919973A2 (pt)
CA (1) CA2741325A1 (pt)
IL (1) IL211984A0 (pt)
MX (1) MX2011004133A (pt)
RU (1) RU2011121511A (pt)
TW (1) TW201020246A (pt)
WO (1) WO2010049331A1 (pt)
ZA (1) ZA201102607B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2768924A1 (en) * 2009-09-21 2011-03-24 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
KR101322617B1 (ko) 2013-07-30 2013-10-29 이화전기공업 주식회사 배터리를 구비한 무정전전원장치의 에너지저장시스템 및 그 운전방법
CN107531606A (zh) * 2015-04-13 2018-01-02 住友精化株式会社 2‑卤代苯甲酸类的制造方法
CN109071447B (zh) * 2016-02-19 2022-04-22 诺华股份有限公司 四环吡啶酮化合物作为抗病毒剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0885885B1 (en) * 1996-02-02 2006-01-04 KumaiI Chemical Industry Co., Ltd. Pyridone derivatives and herbicides
JPH11140054A (ja) * 1997-07-31 1999-05-25 Kumiai Chem Ind Co Ltd 2−ピリドン誘導体及び除草剤
US6323180B1 (en) 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
WO2001085172A1 (en) 2000-05-10 2001-11-15 Smithkline Beecham Corporation Novel anti-infectives
WO2006021340A1 (en) 2004-08-23 2006-03-02 F.Hoffmann-La Roche Ag Heterocyclic antiviral compounds
WO2008104473A2 (en) * 2007-02-28 2008-09-04 F. Hoffmann-La Roche Ag Pyrazolopyriidine derivatives and their use as kinase inhibitors
HRP20110632T1 (hr) 2007-09-17 2011-10-31 Abbott Laboratories N-fenil-diokso-hidropirimidini korisni kao inhibitori virusa hepatitisa c (hcv)
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
MX2011000656A (es) * 2008-07-23 2011-02-23 Hoffmann La Roche Compuestos heterociclicos antiviricos.
RU2015144653A (ru) 2009-03-25 2018-12-29 Эббви Инк. Противовирусные соединения и их применения
RU2552533C2 (ru) 2009-03-25 2015-06-10 Эббви Инк. Противовирусные соединения и их применения

Also Published As

Publication number Publication date
KR20110074941A (ko) 2011-07-04
WO2010049331A1 (en) 2010-05-06
CN102186823A (zh) 2011-09-14
JP2012506888A (ja) 2012-03-22
AR074066A1 (es) 2010-12-22
ZA201102607B (en) 2011-12-28
IL211984A0 (en) 2011-06-30
TW201020246A (en) 2010-06-01
MX2011004133A (es) 2011-05-24
AU2009309813A1 (en) 2010-05-06
RU2011121511A (ru) 2012-12-10
EP2350007A1 (en) 2011-08-03
CA2741325A1 (en) 2010-05-06
US20100111900A1 (en) 2010-05-06
US8232271B2 (en) 2012-07-31

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]