BRPI0920651A2 - moduladores para amiloide beta - Google Patents
moduladores para amiloide betaInfo
- Publication number
- BRPI0920651A2 BRPI0920651A2 BRPI0920651A BRPI0920651A BRPI0920651A2 BR PI0920651 A2 BRPI0920651 A2 BR PI0920651A2 BR PI0920651 A BRPI0920651 A BR PI0920651A BR PI0920651 A BRPI0920651 A BR PI0920651A BR PI0920651 A2 BRPI0920651 A2 BR PI0920651A2
- Authority
- BR
- Brazil
- Prior art keywords
- beta amyloid
- amyloid modulators
- modulators
- beta
- amyloid
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08166228 | 2008-10-09 | ||
| PCT/EP2009/062570 WO2010040661A1 (en) | 2008-10-09 | 2009-09-29 | Modulators for amyloid beta |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0920651A2 true BRPI0920651A2 (pt) | 2016-01-12 |
Family
ID=41278679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0920651A BRPI0920651A2 (pt) | 2008-10-09 | 2009-09-29 | moduladores para amiloide beta |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20100093731A1 (pt) |
| EP (1) | EP2334665B1 (pt) |
| JP (1) | JP5502089B2 (pt) |
| KR (1) | KR101324414B1 (pt) |
| CN (1) | CN102177151A (pt) |
| AR (1) | AR073794A1 (pt) |
| AU (1) | AU2009301210B2 (pt) |
| BR (1) | BRPI0920651A2 (pt) |
| CA (1) | CA2736924C (pt) |
| ES (1) | ES2429517T3 (pt) |
| IL (1) | IL210078A (pt) |
| MX (1) | MX2011003246A (pt) |
| TW (1) | TW201022249A (pt) |
| WO (1) | WO2010040661A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8637525B2 (en) | 2009-07-31 | 2014-01-28 | Bristol-Myers Squibb Company | Compounds for the reduction of beta-amyloid production |
| TWI468402B (zh) | 2009-07-31 | 2015-01-11 | 必治妥美雅史谷比公司 | 降低β－類澱粉生成之化合物 |
| CA2830027C (en) | 2011-03-31 | 2016-04-26 | Pfizer Inc. | Novel bicyclic pyridinones |
| UA110688C2 (uk) | 2012-09-21 | 2016-01-25 | Пфайзер Інк. | Біциклічні піридинони |
| NO3004079T3 (pt) * | 2013-06-04 | 2018-06-16 | ||
| MX368391B (es) | 2015-02-03 | 2019-09-30 | Pfizer | Ciclopropabenzofuranil-piridopirazindionas novedosas. |
| WO2019002183A1 (de) * | 2017-06-26 | 2019-01-03 | Merck Patent Gmbh | Verfahren zur herstellung substituierter stickstoffhaltiger heterocyclen |
| WO2022105852A1 (zh) * | 2020-11-20 | 2022-05-27 | 江苏恒瑞医药股份有限公司 | 三嗪二酮类衍生物、其制备方法及其在医药上的应用 |
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| US6596747B2 (en) * | 1998-10-29 | 2003-07-22 | Bristol-Myers Squibb Company | Compounds derived from an amine nucleus and pharmaceutical compositions comprising same |
| SE9803773D0 (sv) | 1998-11-05 | 1998-11-05 | Astra Pharma Prod | Compounds |
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| JP5328816B2 (ja) * | 2008-02-22 | 2013-10-30 | エフ．ホフマン−ラ ロシュ アーゲー | アミロイドβの調節薬 |
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-
2009
- 2009-09-29 WO PCT/EP2009/062570 patent/WO2010040661A1/en not_active Ceased
- 2009-09-29 MX MX2011003246A patent/MX2011003246A/es active IP Right Grant
- 2009-09-29 CN CN2009801398244A patent/CN102177151A/zh active Pending
- 2009-09-29 JP JP2011529527A patent/JP5502089B2/ja not_active Expired - Fee Related
- 2009-09-29 AU AU2009301210A patent/AU2009301210B2/en not_active Ceased
- 2009-09-29 ES ES09783515T patent/ES2429517T3/es active Active
- 2009-09-29 EP EP09783515.1A patent/EP2334665B1/en not_active Not-in-force
- 2009-09-29 BR BRPI0920651A patent/BRPI0920651A2/pt not_active Application Discontinuation
- 2009-09-29 CA CA2736924A patent/CA2736924C/en not_active Expired - Fee Related
- 2009-09-29 KR KR1020117006396A patent/KR101324414B1/ko not_active Expired - Fee Related
- 2009-10-02 US US12/572,327 patent/US20100093731A1/en not_active Abandoned
- 2009-10-08 AR ARP090103868A patent/AR073794A1/es unknown
- 2009-10-08 TW TW098134150A patent/TW201022249A/zh unknown
-
2010
- 2010-12-16 IL IL210078A patent/IL210078A/en active IP Right Grant
-
2012
- 2012-04-02 US US13/437,057 patent/US8389717B2/en not_active Expired - Fee Related
-
2013
- 2013-01-04 US US13/733,924 patent/US20130143883A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2334665B1 (en) | 2013-07-10 |
| IL210078A0 (en) | 2011-02-28 |
| US20130143883A1 (en) | 2013-06-06 |
| US8389717B2 (en) | 2013-03-05 |
| JP2012504575A (ja) | 2012-02-23 |
| AU2009301210B2 (en) | 2014-05-15 |
| JP5502089B2 (ja) | 2014-05-28 |
| US20100093731A1 (en) | 2010-04-15 |
| CA2736924C (en) | 2016-06-28 |
| TW201022249A (en) | 2010-06-16 |
| CA2736924A1 (en) | 2010-04-15 |
| AR073794A1 (es) | 2010-12-01 |
| KR101324414B1 (ko) | 2013-11-01 |
| CN102177151A (zh) | 2011-09-07 |
| MX2011003246A (es) | 2011-04-21 |
| AU2009301210A1 (en) | 2010-04-15 |
| EP2334665A1 (en) | 2011-06-22 |
| US20120190682A1 (en) | 2012-07-26 |
| IL210078A (en) | 2014-08-31 |
| WO2010040661A1 (en) | 2010-04-15 |
| ES2429517T3 (es) | 2013-11-15 |
| KR20110052712A (ko) | 2011-05-18 |
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