BRPI0921907A2 - Vetor de transferência para inserir um gene em um local genético de uma seqüência de baculovírus, métodos para produzir um bacmid recombinante, um baculovírus recombinante, e, uma ou mais proteínas, bacmid recombinante, baculovírus recombinante, e, célula. - Google Patents

Vetor de transferência para inserir um gene em um local genético de uma seqüência de baculovírus, métodos para produzir um bacmid recombinante, um baculovírus recombinante, e, uma ou mais proteínas, bacmid recombinante, baculovírus recombinante, e, célula.

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Publication number
BRPI0921907A2
BRPI0921907A2 BRPI0921907-2A BRPI0921907A BRPI0921907A2 BR PI0921907 A2 BRPI0921907 A2 BR PI0921907A2 BR PI0921907 A BRPI0921907 A BR PI0921907A BR PI0921907 A2 BRPI0921907 A2 BR PI0921907A2
Authority
BR
Brazil
Prior art keywords
recombinant
baculovirus
bacmid
gene
proteins
Prior art date
Application number
BRPI0921907-2A
Other languages
English (en)
Inventor
Polly Roy
Robert James Noad
Original Assignee
London School Of Hygiene & Tropical Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by London School Of Hygiene & Tropical Medicine filed Critical London School Of Hygiene & Tropical Medicine
Publication of BRPI0921907A2 publication Critical patent/BRPI0921907A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vectore
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14051—Methods of production or purification of viral material
    • C12N2710/14052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BRPI0921907-2A 2008-11-11 2009-11-11 Vetor de transferência para inserir um gene em um local genético de uma seqüência de baculovírus, métodos para produzir um bacmid recombinante, um baculovírus recombinante, e, uma ou mais proteínas, bacmid recombinante, baculovírus recombinante, e, célula. BRPI0921907A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0820631.0A GB0820631D0 (en) 2008-11-11 2008-11-11 Vectors
PCT/GB2009/002647 WO2010055292A2 (en) 2008-11-11 2009-11-11 Vectors

Publications (1)

Publication Number Publication Date
BRPI0921907A2 true BRPI0921907A2 (pt) 2015-08-25

Family

ID=40139744

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0921907-2A BRPI0921907A2 (pt) 2008-11-11 2009-11-11 Vetor de transferência para inserir um gene em um local genético de uma seqüência de baculovírus, métodos para produzir um bacmid recombinante, um baculovírus recombinante, e, uma ou mais proteínas, bacmid recombinante, baculovírus recombinante, e, célula.

Country Status (20)

Country Link
US (2) US9212374B2 (pt)
EP (1) EP2358883B1 (pt)
JP (2) JP5986381B2 (pt)
KR (1) KR20110089420A (pt)
CN (2) CN102245777B (pt)
AU (1) AU2009315471B2 (pt)
BR (1) BRPI0921907A2 (pt)
CA (1) CA2740714A1 (pt)
CL (2) CL2011001056A1 (pt)
CO (1) CO6420360A2 (pt)
ES (1) ES2616855T3 (pt)
GB (1) GB0820631D0 (pt)
MX (2) MX340956B (pt)
MY (1) MY178947A (pt)
PH (1) PH12014501252A1 (pt)
RU (2) RU2569183C2 (pt)
SG (1) SG10201509570TA (pt)
UA (1) UA106733C2 (pt)
WO (1) WO2010055292A2 (pt)
ZA (2) ZA201103286B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0820631D0 (en) 2008-11-11 2008-12-17 London School Hygiene & Tropical Medicine Vectors
AU2011349578B2 (en) 2010-12-23 2016-06-30 Twelve, Inc. System for mitral valve repair and replacement
FR2978456B1 (fr) 2011-07-27 2015-02-20 Genethon Systeme baculoviral pour l'expression d'un vecteur de therapie genique
GB201309132D0 (en) * 2013-05-21 2013-07-03 Biosyntia Aps Regulatable gene expression
RU2590588C1 (ru) * 2015-06-19 2016-07-10 Общество с ограниченной ответственностью "Панацела Лабс" Инновационный центр сколково Способ производства препарата на основе нереплицирующегося вирусного вектора, экспрессирующего ген человеческого toll-подобного рецептора и ген модифицированного белка флагеллина
FR3054841B1 (fr) * 2016-08-05 2021-01-29 Centre Nat Rech Scient Systeme d'expression baculovirus
TWI904068B (zh) 2017-08-09 2025-11-11 美商生物化學醫療公司 核酸分子及其用途
FR3072686B1 (fr) * 2017-10-25 2021-10-22 Centre Nat Rech Scient Systeme d'expression baculovirus
WO2020033863A1 (en) 2018-08-09 2020-02-13 Bioverativ Therapeutics Inc. Nucleic acid molecules and uses thereof for non-viral gene therapy
CN109609552B (zh) * 2018-12-28 2020-04-14 中国科学院武汉物理与数学研究所 重组腺相关病毒的制备方法、系统及重组杆粒
US11708585B2 (en) * 2018-12-28 2023-07-25 Wuhan Institute Of Physics And Mathematics, Chinese Academy Of Sciences Method, system and recombinant bacmid for preparation of recombinant adeno-associated virus
CN114369624B (zh) * 2021-12-30 2023-07-14 华南农业大学 一种降低病毒感染导致的昆虫细胞凋亡的方法
CN118956967A (zh) * 2024-04-17 2024-11-15 和元生物技术（上海）股份有限公司 核酸分子、包含其的重组杆状病毒及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
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IT1257184B (it) * 1992-12-22 1996-01-10 Applied Research Systems Preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale
AU722221B2 (en) * 1996-10-01 2000-07-27 American Cyanamid Company Biological insect control agents expressing insect-specific mite toxin genes, methods and compositions
US6054312A (en) * 1997-08-29 2000-04-25 Selective Genetics, Inc. Receptor-mediated gene delivery using bacteriophage vectors
EP0999284A1 (en) * 1998-09-11 2000-05-10 Hoechst Marion Roussel Method for screening antimycotic substances using essential genes from c.albicans, and said genes
EP1293564A4 (en) * 2000-06-08 2005-08-17 Mitsubishi Pharma Corp EXPRESSION VECTOR FOR SCREENING CELLS HIGH EXPRESSION OF RECOMBINANT PROTEINS, TRANSFORMING HIGH EXPRESSION OF A RECOMBINANT PROTEIN AND USE THEREOF
US6551828B1 (en) * 2000-06-28 2003-04-22 Protemation, Inc. Compositions and methods for generating expression vectors through site-specific recombination
JP4024525B2 (ja) * 2001-11-21 2007-12-19 独立行政法人科学技術振興機構 異なる２つの選択マーカーからなる融合タンパク質
WO2003074714A1 (en) * 2002-03-05 2003-09-12 Stichting Voor De Technische Wetenschappen Baculovirus expression system
EP1501927A2 (en) * 2002-05-02 2005-02-02 University Of North Carolina At Chapel Hill In vitro mutagenesis, phenotyping, and gene mapping
CA2501574C (en) * 2002-10-04 2013-12-03 E. I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
CA2558313C (en) * 2004-03-09 2011-05-17 Eidgenoessische Technische Hochschule Zurich New expression tools for multiprotein applications
FR2877013A1 (fr) * 2004-10-27 2006-04-28 Assist Publ Hopitaux De Paris Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez
EP1783228A1 (en) 2005-11-08 2007-05-09 ETH Zürich Recombinant expression of multiprotein complexes using polygenes
GB0605265D0 (en) * 2006-03-15 2006-04-26 London School Hygiene & Tropical Medicine Virus-like particles of rift valley fever virus
GB0820631D0 (en) 2008-11-11 2008-12-17 London School Hygiene & Tropical Medicine Vectors

Also Published As

Publication number Publication date
UA106733C2 (uk) 2014-10-10
AU2009315471A1 (en) 2010-05-20
MX2011004902A (es) 2011-06-16
AU2009315471B2 (en) 2014-07-10
ZA201203945B (en) 2013-01-31
CN102245777A (zh) 2011-11-16
US20110281261A1 (en) 2011-11-17
CL2011001056A1 (es) 2011-10-14
CO6420360A2 (es) 2012-04-16
JP5986381B2 (ja) 2016-09-06
US20160090575A1 (en) 2016-03-31
CN105400818A (zh) 2016-03-16
RU2569183C2 (ru) 2015-11-20
CN102245777B (zh) 2016-05-11
EP2358883A2 (en) 2011-08-24
ZA201103286B (en) 2012-10-31
KR20110089420A (ko) 2011-08-08
JP2012508004A (ja) 2012-04-05
US9777260B2 (en) 2017-10-03
GB0820631D0 (en) 2008-12-17
JP2016101164A (ja) 2016-06-02
ES2616855T3 (es) 2017-06-14
CA2740714A1 (en) 2010-05-20
US9212374B2 (en) 2015-12-15
WO2010055292A2 (en) 2010-05-20
RU2011114814A (ru) 2012-12-20
WO2010055292A3 (en) 2010-08-26
RU2014145441A (ru) 2015-06-20
EP2358883B1 (en) 2016-12-07
MY178947A (en) 2020-10-23
SG10201509570TA (en) 2015-12-30
CL2015000113A1 (es) 2015-06-19
MX340956B (es) 2016-07-29
PH12014501252A1 (en) 2015-10-05

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