BRPI0922972A2 - Processo de preparo de ésteres ativados. - Google Patents
Processo de preparo de ésteres ativados.Info
- Publication number
- BRPI0922972A2 BRPI0922972A2 BRPI0922972-8A BRPI0922972A BRPI0922972A2 BR PI0922972 A2 BRPI0922972 A2 BR PI0922972A2 BR PI0922972 A BRPI0922972 A BR PI0922972A BR PI0922972 A2 BRPI0922972 A2 BR PI0922972A2
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- activated esters
- esters
- activated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0807090A FR2939795B1 (fr) | 2008-12-17 | 2008-12-17 | Procede de preparation d'esters actives |
| FR08/07090 | 2008-12-17 | ||
| PCT/FR2009/052528 WO2010076474A1 (fr) | 2008-12-17 | 2009-12-15 | Procede de preparation d'esters actives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0922972A2 true BRPI0922972A2 (pt) | 2015-08-11 |
| BRPI0922972A8 BRPI0922972A8 (pt) | 2018-02-06 |
| BRPI0922972B1 BRPI0922972B1 (pt) | 2021-06-01 |
Family
ID=40614691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0922972-8A BRPI0922972B1 (pt) | 2008-12-17 | 2009-12-15 | Processo de preparação de ésteres ativados, bem como sal de diciclohexilamina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8314244B2 (pt) |
| EP (1) | EP2379501B1 (pt) |
| JP (1) | JP5467111B2 (pt) |
| KR (1) | KR101645051B1 (pt) |
| CN (1) | CN102292318B (pt) |
| AU (1) | AU2009334689B2 (pt) |
| BR (1) | BRPI0922972B1 (pt) |
| CA (1) | CA2747105C (pt) |
| CY (1) | CY1115035T1 (pt) |
| DK (1) | DK2379501T3 (pt) |
| ES (1) | ES2459918T3 (pt) |
| FR (1) | FR2939795B1 (pt) |
| HR (1) | HRP20140368T1 (pt) |
| IL (1) | IL213525A (pt) |
| ME (1) | ME01827B (pt) |
| MX (1) | MX2011006624A (pt) |
| MY (1) | MY156761A (pt) |
| PL (1) | PL2379501T4 (pt) |
| PT (1) | PT2379501E (pt) |
| RS (1) | RS53267B (pt) |
| RU (1) | RU2506258C2 (pt) |
| SG (1) | SG172179A1 (pt) |
| SI (1) | SI2379501T1 (pt) |
| SM (1) | SMT201400061B (pt) |
| WO (1) | WO2010076474A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2963007B1 (fr) | 2010-07-26 | 2013-04-05 | Sanofi Aventis | Derives anticancereux, leur preparation et leur application therapeutique |
| US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
| JP6774748B2 (ja) * | 2014-08-13 | 2020-10-28 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 強められたｍｓ信号を有するグリカンおよび他の生体分子の迅速蛍光タグ付け |
| EP3213056B1 (en) | 2014-10-30 | 2020-08-12 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
| WO2016077548A1 (en) | 2014-11-13 | 2016-05-19 | Waters Technologies Corporation | Methods for liquid chromatography calibration for rapid labeled n-glycans |
| US11035832B2 (en) | 2016-06-21 | 2021-06-15 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
| EP3472132A4 (en) | 2016-06-21 | 2020-01-15 | Waters Technologies Corporation | FLUORESCENCE LABELING OF GLYCANS AND OTHER BIOMOLECULES BY REDUCING AMINATION FOR IMPROVED MASS SPECTROMETRY SIGNALS |
| EP3479103B1 (en) | 2016-07-01 | 2022-04-20 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5710101B2 (pt) * | 1972-10-24 | 1982-02-24 | ||
| US5892057A (en) | 1997-09-18 | 1999-04-06 | Pierce Chemical Company | Preparation of sulfo-N-hydroxysuccinimide salts |
| US5872261A (en) | 1997-09-18 | 1999-02-16 | Pierce Chemical Company | Preparation of sulfo-N- hydroxy succinimide salts with intermediate formation of diester |
| JP2002316987A (ja) * | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ２−アルコキシベンゼン誘導体を含有する医薬 |
| DE60336149D1 (de) * | 2002-08-16 | 2011-04-07 | Immunogen Inc | Vernetzer mit hoher reaktivität und löslichkeit und ihre verwendung bei der herstellung von konjugaten für die gezielte abgabe von kleinmolekularen arzneimitteln |
| JP4929461B2 (ja) * | 2004-10-29 | 2012-05-09 | 国立大学法人富山大学 | 高蛍光量子収率型疎水性蛍光プローブ、それを用いる生体高分子検出法ならびに生体高分子間相互作用検出法 |
| ATE472560T1 (de) * | 2004-11-09 | 2010-07-15 | Basf Se | N-substituierte imide als polymerisatiosinitiatoren |
| US8871720B2 (en) * | 2005-07-07 | 2014-10-28 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the C-terminus |
-
2008
- 2008-12-17 FR FR0807090A patent/FR2939795B1/fr active Active
-
2009
- 2009-12-15 BR BRPI0922972-8A patent/BRPI0922972B1/pt not_active IP Right Cessation
- 2009-12-15 RU RU2011129652/04A patent/RU2506258C2/ru active
- 2009-12-15 AU AU2009334689A patent/AU2009334689B2/en not_active Ceased
- 2009-12-15 DK DK09802171.0T patent/DK2379501T3/da active
- 2009-12-15 CA CA2747105A patent/CA2747105C/fr active Active
- 2009-12-15 JP JP2011541550A patent/JP5467111B2/ja not_active Expired - Fee Related
- 2009-12-15 ME MEP-2014-44A patent/ME01827B/me unknown
- 2009-12-15 EP EP09802171.0A patent/EP2379501B1/fr active Active
- 2009-12-15 WO PCT/FR2009/052528 patent/WO2010076474A1/fr not_active Ceased
- 2009-12-15 SI SI200930916T patent/SI2379501T1/sl unknown
- 2009-12-15 SG SG2011043817A patent/SG172179A1/en unknown
- 2009-12-15 PT PT98021710T patent/PT2379501E/pt unknown
- 2009-12-15 US US13/140,254 patent/US8314244B2/en active Active
- 2009-12-15 MY MYPI2011002758A patent/MY156761A/en unknown
- 2009-12-15 PL PL09802171T patent/PL2379501T4/pl unknown
- 2009-12-15 ES ES09802171.0T patent/ES2459918T3/es active Active
- 2009-12-15 RS RS20140198A patent/RS53267B/sr unknown
- 2009-12-15 MX MX2011006624A patent/MX2011006624A/es active IP Right Grant
- 2009-12-15 HR HRP20140368AT patent/HRP20140368T1/hr unknown
- 2009-12-15 CN CN200980154947.5A patent/CN102292318B/zh not_active Expired - Fee Related
- 2009-12-15 KR KR1020117013765A patent/KR101645051B1/ko not_active Expired - Fee Related
-
2011
- 2011-06-13 IL IL213525A patent/IL213525A/en active IP Right Grant
-
2014
- 2014-04-22 CY CY20141100299T patent/CY1115035T1/el unknown
- 2014-05-26 SM SM201400061T patent/SMT201400061B/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25G | Requested change of headquarter approved |
Owner name: SANOFI (FR) |
|
| B25A | Requested transfer of rights approved |
Owner name: IMMONUGEN, INC. (US) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/12/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 16A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2859 DE 21-10-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |