BRPI0923602A2 - derivados de benzotiazolona - Google Patents

derivados de benzotiazolona

Info

Publication number
BRPI0923602A2
BRPI0923602A2 BRPI0923602A BRPI0923602A BRPI0923602A2 BR PI0923602 A2 BRPI0923602 A2 BR PI0923602A2 BR PI0923602 A BRPI0923602 A BR PI0923602A BR PI0923602 A BRPI0923602 A BR PI0923602A BR PI0923602 A2 BRPI0923602 A2 BR PI0923602A2
Authority
BR
Brazil
Prior art keywords
benzothiazolone derivatives
benzothiazolone
derivatives
Prior art date
Application number
BRPI0923602A
Other languages
English (en)
Inventor
Andree Blaukat
Dieter Dorsch
Frank Stieber
Oliver Schadt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BRPI0923602A2 publication Critical patent/BRPI0923602A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0923602A 2009-01-07 2009-12-08 derivados de benzotiazolona BRPI0923602A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009003975A DE102009003975A1 (de) 2009-01-07 2009-01-07 Benzothiazolonderivate
PCT/EP2009/008756 WO2010078905A1 (de) 2009-01-07 2009-12-08 Benzothiazolonderivate

Publications (1)

Publication Number Publication Date
BRPI0923602A2 true BRPI0923602A2 (pt) 2016-01-12

Family

ID=41600341

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923602A BRPI0923602A2 (pt) 2009-01-07 2009-12-08 derivados de benzotiazolona

Country Status (16)

Country Link
US (1) US8877751B2 (pt)
EP (1) EP2373635A1 (pt)
JP (1) JP5653933B2 (pt)
KR (1) KR20110102504A (pt)
CN (1) CN102272112A (pt)
AR (1) AR074989A1 (pt)
AU (1) AU2009336847B2 (pt)
BR (1) BRPI0923602A2 (pt)
CA (1) CA2748908C (pt)
DE (1) DE102009003975A1 (pt)
EA (1) EA021067B1 (pt)
IL (1) IL213827A (pt)
MX (1) MX2011007232A (pt)
SG (1) SG172424A1 (pt)
WO (1) WO2010078905A1 (pt)
ZA (1) ZA201105779B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA38354B1 (fr) * 2013-02-28 2016-09-30 Novartis Ag Préparation contenant un composé de benzothiazolone
EP2933245A1 (en) * 2014-04-17 2015-10-21 Bayer Technology Services GmbH Oxidative carbonylation of amino aryl compounds by aryl formates
US10750742B2 (en) 2015-12-22 2020-08-25 Syngenta Participations Ag Pesticidally active pyrazole derivatives
CN113365997B (zh) * 2019-02-01 2022-06-07 南京明德新药研发有限公司 作为c-Met抑制剂的含嘧啶基团的三并环类化合物
CN115583939A (zh) * 2022-11-04 2023-01-10 苏州莱安医药化学技术有限公司 一种特泊替尼中间体的合成方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
WO1997030035A1 (en) 1996-02-13 1997-08-21 Zeneca Limited Quinazoline derivatives as vegf inhibitors
ES2169355T3 (es) 1996-03-05 2002-07-01 Astrazeneca Ab Derivados de 4-anilinoquinazolina.
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
BR0112224A (pt) 2000-07-07 2003-06-10 Angiogene Pharm Ltd Composto, composição farmacêutica, uso de um composto ou de um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo, e, processo para preparar um composto
HUP0301742A3 (en) 2000-07-07 2005-08-29 Angiogene Pharm Ltd Colchinol derivatives as angiogenesis inhibitors, process for producing them, pharmaceutical compositions containing them and their use
WO2002096361A2 (en) 2001-05-30 2002-12-05 Sugen, Inc. 5-aralkylsulfonyl-3- (pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
CA2454538A1 (en) 2001-06-22 2003-01-03 Kirin Beer Kabushiki Kaisha Quinoline derivatives and quinazoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same
US20040259863A1 (en) 2001-10-31 2004-12-23 Hans-Michael Eggenweiler Type 4 phosphodiesterase inhibitors and uses thereof
AU2003249597B2 (en) 2002-03-08 2007-06-28 Merck Sharp & Dohme Corp. Mitotic kinesin inhibitors
JP2007516180A (ja) 2003-07-02 2007-06-21 スゲン，インコーポレイティド ｃ−Ｍｅｔ阻害薬としてのアリールメチルトリアゾロおよびイミダゾピラジン類
CA2744997A1 (en) 2003-09-26 2005-04-07 Exelixis, Inc. C-met modulators and method of use
WO2006014325A2 (en) 2004-07-02 2006-02-09 Exelixis, Inc. C-met modulators and method of use
DE102004036581A1 (de) 2004-07-28 2006-03-23 Robert Bosch Gmbh Verfahren zum Betreiben eines Hybridantriebs und Vorrichtung zur Durchführung des Verfahrens
CH697191A5 (de) 2004-07-29 2008-06-25 Biospectra Ag Mehrfach-Bioreaktorvorrichtung.
EP1621785A1 (en) 2004-07-30 2006-02-01 Mecos Traxler AG Method and apparatus for controlling a magnetic bearing device
ATE492544T1 (de) 2004-08-26 2011-01-15 Pfizer Pyrazol-substituierte aminoheteroarylverbindungen als proteinkinasehemmer
JP2008524246A (ja) 2004-12-16 2008-07-10 タケダ サン ディエゴ インコーポレイテッド ヒストンデアセチラーゼ阻害剤
CA2601884A1 (en) 2005-03-18 2006-09-21 Surendrakumar Satyanarayan Pandey Novel tyrosine derivatives
DE102005038537A1 (de) 2005-08-16 2007-02-22 Merck Patent Gmbh 1-Acyldihydropyrazolderivate
DE102005055354A1 (de) * 2005-11-21 2007-10-31 Merck Patent Gmbh Substituierte 5-Phenyl-3,6-dihydro-2-oxo-6H-[1,3,4]thiadiazine
DE102007026341A1 (de) * 2007-06-06 2008-12-11 Merck Patent Gmbh Benzoxazolonderivate

Also Published As

Publication number Publication date
ZA201105779B (en) 2012-04-25
EA201101042A1 (ru) 2012-01-30
EA021067B1 (ru) 2015-03-31
KR20110102504A (ko) 2011-09-16
MX2011007232A (es) 2011-08-03
WO2010078905A1 (de) 2010-07-15
JP5653933B2 (ja) 2015-01-14
AU2009336847A1 (en) 2011-08-25
CA2748908C (en) 2017-10-24
US8877751B2 (en) 2014-11-04
CN102272112A (zh) 2011-12-07
CA2748908A1 (en) 2010-07-15
EP2373635A1 (de) 2011-10-12
US20110269756A1 (en) 2011-11-03
AR074989A1 (es) 2011-03-02
SG172424A1 (en) 2011-07-28
IL213827A0 (en) 2011-07-31
IL213827A (en) 2015-05-31
JP2012514610A (ja) 2012-06-28
AU2009336847B2 (en) 2015-12-10
DE102009003975A1 (de) 2010-07-08

Similar Documents

Publication Publication Date Title
BRPI1013246A2 (pt) derivados de benzofuralina
BR112012002828A2 (pt) derivados de 5-fluorpirimidinona
EP2462134A4 (en) N1-sulfonyl-5-FLUORPYRIMIDINON DERIVATIVES
BRPI1013844A2 (pt) derivados de piridina-isoxazol
BRPI1006128A2 (pt) derivados de sulfonamida
ECSP12011999A (es) Derivados benzamida sustituidos
EP2433940A4 (en) SPIROIMIDAZOLONDERIVAT
BRPI1012770A2 (pt) derivados de tiofeno
BR112012002662A2 (pt) derivados de bis-benzimidazol
BR112012004969A2 (pt) derivados de bis-benzimidazol
BR112012015868A2 (pt) derivados de imidazolidinadiona
DK2397480T3 (da) Diazepindionderivat
BRPI0915064A2 (pt) derivados de qunoxalinadiona
BRPI1012902A2 (pt) conjuntos de sensor de desenvolvimento
BRPI1005525A2 (pt) compostos de azaazuleno
BRPI0913832A2 (pt) derivados de pirrolopiridinilpirimidin-2-ilamina
BRPI1014454A2 (pt) derivados de isoxazol-pirazol
BR112012002810A2 (pt) derivados de n1-acil-5-fluoropirimidinona
DK2387580T3 (da) Deoxyactagardinderivater
BR112012005503A2 (pt) derivados de isoxazolidina
EP2495246A4 (en) FULLER DERIVATIVE
BRPI0922652A2 (pt) Derivados de quinazolinamida
BRPI0913234A2 (pt) derivados de tiazolilpiperidina
EP2401281A4 (en) PYRIMIDINPYRIMIDOINDAZOLDERIVAT
ECSP12011977A (es) Derivados de etinilo

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.