ECSP12011977A - Derivados de etinilo - Google Patents
Derivados de etiniloInfo
- Publication number
- ECSP12011977A ECSP12011977A ECSP12011977A ECSP12011977A EC SP12011977 A ECSP12011977 A EC SP12011977A EC SP12011977 A ECSP12011977 A EC SP12011977A EC SP12011977 A ECSP12011977 A EC SP12011977A
- Authority
- EC
- Ecuador
- Prior art keywords
- ethylene derivatives
- derivatives
- ethylene
- Prior art date
Links
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical class C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179719 | 2009-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP12011977A true ECSP12011977A (es) | 2012-07-31 |
Family
ID=43446449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP12011977 ECSP12011977A (es) | 2009-12-17 | 2012-06-15 | Derivados de etinilo |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US8586581B2 (es) |
| EP (1) | EP2513102B1 (es) |
| JP (1) | JP5763094B2 (es) |
| KR (1) | KR101407856B1 (es) |
| CN (1) | CN102686589B (es) |
| AR (1) | AR079467A1 (es) |
| AU (1) | AU2010332987B2 (es) |
| BR (1) | BR112012014770A2 (es) |
| CA (1) | CA2780155A1 (es) |
| CL (1) | CL2012001596A1 (es) |
| CO (1) | CO6531478A2 (es) |
| CR (1) | CR20120269A (es) |
| EC (1) | ECSP12011977A (es) |
| ES (1) | ES2551582T3 (es) |
| IL (1) | IL219371A (es) |
| MA (1) | MA33802B1 (es) |
| MX (1) | MX2012006789A (es) |
| MY (1) | MY162998A (es) |
| NZ (1) | NZ599553A (es) |
| PE (1) | PE20121443A1 (es) |
| PH (1) | PH12012500867A1 (es) |
| RU (1) | RU2553461C2 (es) |
| SG (1) | SG181779A1 (es) |
| TW (1) | TWI448465B (es) |
| UA (1) | UA107002C2 (es) |
| WO (1) | WO2011073172A1 (es) |
| ZA (1) | ZA201204429B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3006745C (en) * | 2010-11-05 | 2021-03-30 | Oat Agrio Co., Ltd. | Ethynylphenylamidine compound or salt thereof, method for producing same, and fungicide for agricultural and horticultural use |
| CA2829170C (en) | 2011-04-26 | 2019-02-26 | F. Hoffmann-La Roche Ag | Ethynyl derivatives as positive allosteric modulators of the mglur5 |
| US20130123254A1 (en) | 2011-09-30 | 2013-05-16 | Barbara Biemans | Pharmaceutically acceptable mglur5 positive allosteric modulators and their methods of identification |
| UA110862C2 (uk) * | 2011-10-07 | 2016-02-25 | Ф. Хоффманн-Ля Рош Аг | Похідні етинілу як алостеричні модулятори метаботропного рецептора глутамату mglur 5 |
| WO2014056710A1 (en) * | 2012-09-27 | 2014-04-17 | F. Hoffmann-La Roche Ag | Arylethynyl derivatives |
| CN104603110B (zh) * | 2012-10-18 | 2016-08-31 | 霍夫曼-拉罗奇有限公司 | 作为mGluR5受体活性的调节剂的乙炔基衍生物 |
| CN104768554B (zh) * | 2012-11-07 | 2018-04-17 | 霍夫曼-拉罗奇有限公司 | 三唑并化合物 |
| JP6603334B2 (ja) | 2015-06-03 | 2019-11-06 | エフ.ホフマン−ラ ロシュ アーゲー | エチニル誘導体 |
| LT3322701T (lt) | 2015-07-15 | 2019-07-10 | F. Hoffmann-La Roche Ag | Etinilo dariniai kaip metabotropinių glutamato receptorių moduliatoriai |
| CR20190014A (es) | 2016-07-18 | 2019-03-04 | Hoffmann La Roche | Derivados etinilo |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002526408A (ja) * | 1998-10-02 | 2002-08-20 | ノバルティス アクチエンゲゼルシャフト | 疼痛および不安の処置のためのmglur5アンタゴニスト |
| CO5271680A1 (es) * | 2000-02-21 | 2003-04-30 | Smithkline Beecham Corp | Compuestos |
| GB0027987D0 (en) * | 2000-11-16 | 2001-01-03 | Smithkline Beecham Plc | Compounds |
| US6910976B2 (en) | 2001-06-26 | 2005-06-28 | Stx, Llc | Multi-component lacrosse stick head |
| GB0127430D0 (en) * | 2001-11-15 | 2002-01-09 | Smithkline Beecham Corp | Compounds |
| GB0127433D0 (en) * | 2001-11-15 | 2002-01-09 | Smithkline Beecham Corp | Compounds |
| TWI292318B (en) * | 2003-03-10 | 2008-01-11 | Hoffmann La Roche | Imidazol-4-yl-ethynyl-pyridine derivatives |
| GB0325956D0 (en) | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
| GB0413605D0 (en) | 2004-06-17 | 2004-07-21 | Addex Pharmaceuticals Sa | Novel compounds |
| WO2006048771A1 (en) | 2004-11-04 | 2006-05-11 | Addex Pharmaceuticals Sa | Novel tetrazole derivatives as positive allosteric modulators of metabotropic glutamate receptors |
| GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
| EP2308870A3 (en) * | 2005-06-01 | 2011-10-19 | UCB Pharma S.A. | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses |
| KR101086967B1 (ko) | 2005-11-15 | 2011-11-29 | 어레이 바이오파마 인크. | 과다증식성 질환의 치료를 위한 erbb 유형 i 수용체티로신 키나제 억제제로서의 n4-페닐-퀴나졸린-4-아민유도체 및 관련 화합물 |
| KR20090024270A (ko) | 2006-06-30 | 2009-03-06 | 아스트라제네카 아베 | 암 치료에 유용한 피리미딘 유도체 |
| EP1972628A1 (en) | 2007-03-21 | 2008-09-24 | Schwarz Pharma Ag | Indolizines and aza-analog derivatives thereof as CNS active compounds |
| AU2008245458B2 (en) * | 2007-04-30 | 2013-01-10 | Abbvie Inc. | Inhibitors of diacylglycerol O-acyltransferase type 1 enzyme |
| EP2162136A4 (en) | 2007-06-03 | 2012-02-15 | Univ Vanderbilt | GLUTAMATE METABOTROPIC POSITIVE RECEPTOR-BASED ALLOSTERIC-MODULATOR BENZAMIDE DERIVATIVES (MGLUR5) AND METHODS OF MAKING AND USING THEM |
| TW201116532A (en) * | 2009-08-05 | 2011-05-16 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
-
2010
- 2010-12-10 US US12/964,785 patent/US8586581B2/en not_active Expired - Fee Related
- 2010-12-14 NZ NZ599553A patent/NZ599553A/en not_active IP Right Cessation
- 2010-12-14 MY MYPI2012002710A patent/MY162998A/en unknown
- 2010-12-14 RU RU2012128551/04A patent/RU2553461C2/ru not_active IP Right Cessation
- 2010-12-14 ES ES10790960.8T patent/ES2551582T3/es active Active
- 2010-12-14 JP JP2012543676A patent/JP5763094B2/ja not_active Expired - Fee Related
- 2010-12-14 PH PH1/2012/500867A patent/PH12012500867A1/en unknown
- 2010-12-14 KR KR1020127018589A patent/KR101407856B1/ko not_active Expired - Fee Related
- 2010-12-14 AU AU2010332987A patent/AU2010332987B2/en not_active Ceased
- 2010-12-14 MX MX2012006789A patent/MX2012006789A/es active IP Right Grant
- 2010-12-14 SG SG2012044814A patent/SG181779A1/en unknown
- 2010-12-14 CA CA2780155A patent/CA2780155A1/en not_active Abandoned
- 2010-12-14 WO PCT/EP2010/069593 patent/WO2011073172A1/en not_active Ceased
- 2010-12-14 EP EP10790960.8A patent/EP2513102B1/en not_active Not-in-force
- 2010-12-14 PE PE2012000817A patent/PE20121443A1/es not_active Application Discontinuation
- 2010-12-14 TW TW099143811A patent/TWI448465B/zh not_active IP Right Cessation
- 2010-12-14 UA UAA201207427A patent/UA107002C2/uk unknown
- 2010-12-14 CN CN201080057081.9A patent/CN102686589B/zh not_active Expired - Fee Related
- 2010-12-14 BR BR112012014770A patent/BR112012014770A2/pt not_active Application Discontinuation
- 2010-12-15 AR ARP100104641A patent/AR079467A1/es unknown
-
2012
- 2012-04-23 IL IL219371A patent/IL219371A/en not_active IP Right Cessation
- 2012-04-25 CO CO12068169A patent/CO6531478A2/es active IP Right Grant
- 2012-05-22 CR CR20120269A patent/CR20120269A/es unknown
- 2012-05-24 MA MA34890A patent/MA33802B1/fr unknown
- 2012-06-14 CL CL2012001596A patent/CL2012001596A1/es unknown
- 2012-06-15 EC ECSP12011977 patent/ECSP12011977A/es unknown
- 2012-06-15 ZA ZA2012/04429A patent/ZA201204429B/en unknown
-
2013
- 2013-10-16 US US14/055,047 patent/US8933094B2/en not_active Expired - Fee Related
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