BRPI1008356A2 - "sal de adição ácido de udenafil, respectivo método de preparação e composição farmacêutica" - Google Patents
"sal de adição ácido de udenafil, respectivo método de preparação e composição farmacêutica"Info
- Publication number
- BRPI1008356A2 BRPI1008356A2 BRPI1008356-1A BRPI1008356A BRPI1008356A2 BR PI1008356 A2 BRPI1008356 A2 BR PI1008356A2 BR PI1008356 A BRPI1008356 A BR PI1008356A BR PI1008356 A2 BRPI1008356 A2 BR PI1008356A2
- Authority
- BR
- Brazil
- Prior art keywords
- udenafil
- preparation
- pharmaceutical composition
- acid addition
- addition salt
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- IYFNEFQTYQPVOC-UHFFFAOYSA-N udenafil Chemical compound C1=C(C=2NC=3C(CCC)=NN(C)C=3C(=O)N=2)C(OCCC)=CC=C1S(=O)(=O)NCCC1CCCN1C IYFNEFQTYQPVOC-UHFFFAOYSA-N 0.000 title 1
- 229960000438 udenafil Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020090013350A KR101071877B1 (ko) | 2009-02-18 | 2009-02-18 | 유데나필 산부가염, 그의 제조방법 및 이를 포함하는 약학적 조성물 |
| PCT/KR2010/000976 WO2010095849A2 (en) | 2009-02-18 | 2010-02-17 | Acid addition salt of udenafil, preparation method thereof and phamaceutical composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1008356A2 true BRPI1008356A2 (pt) | 2015-08-25 |
Family
ID=42634317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008356-1A BRPI1008356A2 (pt) | 2009-02-18 | 2010-02-17 | "sal de adição ácido de udenafil, respectivo método de preparação e composição farmacêutica" |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20110306762A1 (pt) |
| EP (1) | EP2398804A4 (pt) |
| JP (1) | JP2012517999A (pt) |
| KR (1) | KR101071877B1 (pt) |
| CN (1) | CN102325774A (pt) |
| AU (1) | AU2010216577A1 (pt) |
| BR (1) | BRPI1008356A2 (pt) |
| CA (1) | CA2751639A1 (pt) |
| MX (1) | MX2011008644A (pt) |
| RU (1) | RU2011134011A (pt) |
| SG (1) | SG173733A1 (pt) |
| WO (1) | WO2010095849A2 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011506374A (ja) * | 2007-12-12 | 2011-03-03 | ウルティモルフィクス・テクノロジーズ・ベー・フェー | テノホビルジソプロキシルの固形物 |
| TWI462739B (zh) * | 2010-11-02 | 2014-12-01 | Univ Kaohsiung Medical | Ｓｉｌｄｅｎａｆｉｌ－同族物四級銨哌嗪鹽類之製備及醫療用途 |
| CN102952138B (zh) * | 2011-08-17 | 2016-07-06 | 上海特化医药科技有限公司 | 一种吡唑并嘧啶酮化合物的盐、多晶型物及其药物组合物、制备方法和应用 |
| WO2015089105A1 (en) | 2013-12-09 | 2015-06-18 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
| IL285193B2 (en) | 2014-08-12 | 2023-11-01 | Mezzion Pharma Co Ltd | Methods to improve heart muscle function in Fontan surgery patients using iodenafil compounds |
| JP2019513143A (ja) * | 2016-03-28 | 2019-05-23 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 新規塩類および結晶 |
| MX2022003593A (es) | 2019-09-24 | 2022-09-19 | Mezzion Pharma Co Ltd | Métodos para mejorar el rendimiento del ejercicio, el rendimiento ventricular único y el índice de rendimiento del miocardio (mpi) en la enfermedad cardiaca del ventrículo único, utilizando composiciones de udenafil. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100353014B1 (ko) * | 1998-11-11 | 2002-09-18 | 동아제약 주식회사 | 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물 |
| JP2008546786A (ja) * | 2005-06-23 | 2008-12-25 | シェーリング コーポレイション | Ｐｄｅ５インヒビターの迅速吸収性経口処方物 |
| KR101304343B1 (ko) * | 2006-04-06 | 2013-09-11 | 한미사이언스 주식회사 | Ｐｄｅ-5 억제제의 경구용 속용제형 |
| MX2009003941A (es) * | 2006-10-20 | 2009-04-24 | Concert Pharmaceuticals Inc | Derivados de 3-(dihidro-1h-pirazolo[4,3-d]pirimidin-5-il)-4-propox ibencenosulfonamida y metodos de uso. |
| EP2106792A1 (en) * | 2008-04-02 | 2009-10-07 | Pelvipharm | Use of a combination of udenafil and alfuzosin or oxybutynin for the treatment of overactive bladder |
-
2009
- 2009-02-18 KR KR1020090013350A patent/KR101071877B1/ko not_active Expired - Fee Related
-
2010
- 2010-02-17 CN CN2010800084473A patent/CN102325774A/zh active Pending
- 2010-02-17 JP JP2011550069A patent/JP2012517999A/ja active Pending
- 2010-02-17 EP EP10743924A patent/EP2398804A4/en not_active Withdrawn
- 2010-02-17 CA CA2751639A patent/CA2751639A1/en not_active Abandoned
- 2010-02-17 RU RU2011134011/04A patent/RU2011134011A/ru not_active Application Discontinuation
- 2010-02-17 US US13/201,900 patent/US20110306762A1/en not_active Abandoned
- 2010-02-17 MX MX2011008644A patent/MX2011008644A/es unknown
- 2010-02-17 AU AU2010216577A patent/AU2010216577A1/en not_active Abandoned
- 2010-02-17 BR BRPI1008356-1A patent/BRPI1008356A2/pt not_active IP Right Cessation
- 2010-02-17 WO PCT/KR2010/000976 patent/WO2010095849A2/en not_active Ceased
- 2010-02-17 SG SG2011059201A patent/SG173733A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010216577A1 (en) | 2011-09-01 |
| MX2011008644A (es) | 2011-09-27 |
| US20110306762A1 (en) | 2011-12-15 |
| CN102325774A (zh) | 2012-01-18 |
| WO2010095849A2 (en) | 2010-08-26 |
| WO2010095849A3 (en) | 2010-12-09 |
| CA2751639A1 (en) | 2010-08-26 |
| JP2012517999A (ja) | 2012-08-09 |
| KR101071877B1 (ko) | 2011-10-10 |
| KR20100094097A (ko) | 2010-08-26 |
| EP2398804A4 (en) | 2012-08-15 |
| SG173733A1 (en) | 2011-09-29 |
| EP2398804A2 (en) | 2011-12-28 |
| RU2011134011A (ru) | 2013-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |