CA1083573A - N-substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them - Google Patents

N-substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them

Info

Publication number
CA1083573A
CA1083573A CA253,973A CA253973A CA1083573A CA 1083573 A CA1083573 A CA 1083573A CA 253973 A CA253973 A CA 253973A CA 1083573 A CA1083573 A CA 1083573A
Authority
CA
Canada
Prior art keywords
methoxy
amino
group
chloro
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA253,973A
Other languages
English (en)
French (fr)
Inventor
Robert C. Moreau
Jean-Paul Fournier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Choay SA
Original Assignee
Choay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay SA filed Critical Choay SA
Application granted granted Critical
Publication of CA1083573A publication Critical patent/CA1083573A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
CA253,973A 1975-06-09 1976-06-03 N-substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them Expired CA1083573A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7517973A FR2313918A1 (fr) 1975-06-09 1975-06-09 Methoxy-2 benzenesulfonamides n-substitues, procede pour les preparer et medicaments les contenant
FR7517973 1975-06-09

Publications (1)

Publication Number Publication Date
CA1083573A true CA1083573A (en) 1980-08-12

Family

ID=9156225

Family Applications (1)

Application Number Title Priority Date Filing Date
CA253,973A Expired CA1083573A (en) 1975-06-09 1976-06-03 N-substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them

Country Status (13)

Country Link
US (1) US4132786A (2)
JP (2) JPS6049630B2 (2)
AT (1) AT358555B (2)
BE (1) BE842753A (2)
CA (1) CA1083573A (2)
CH (1) CH616917A5 (2)
DE (1) DE2623447A1 (2)
DK (1) DK146592C (2)
ES (1) ES448646A1 (2)
FR (1) FR2313918A1 (2)
GB (1) GB1545628A (2)
NL (1) NL7606172A (2)
SE (1) SE430248B (2)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ193654A (en) * 1979-05-16 1984-08-24 Wuelfing Johann A Naphthalene sulphonamido-alkyl-piperidines,pyrrolidines or piperazines and pharmaceutical compositions
EP0021592B1 (en) * 1979-05-23 1983-09-28 BEECHAM - WUELFING GmbH & Co. KG Phenylsulphonamide derivatives, a process for their preparation and their use as medicines
FR2504528A1 (fr) * 1981-04-23 1982-10-29 Choay Sa Dialcoxy (2,4) benzenesulfonamides n-substitues
US4714700A (en) * 1982-04-20 1987-12-22 Choay S.A. N-substituted 2,4-dialkoxy benzenesulfonamides and pharmaceutical compositions
US4483864A (en) * 1983-02-04 1984-11-20 University Of Iowa Research Foundation Non-classical topical treatment for glaucoma
GB2160201B (en) * 1984-06-14 1988-05-11 Wyeth John & Brother Ltd Quinazoline and cinnoline derivatives
US4629738A (en) * 1984-06-25 1986-12-16 University Of Iowa Research Foundation Non-classical topical treatment for glaucoma
US4731369A (en) * 1985-11-06 1988-03-15 Merck & Co. Inc. Amides and esters of 2-(N-(hydroxypiperidinoalkyl) and (hydroxypyrrolidinoalkyl)-aminosulfonyl)-6-nitrobenzoic acids useful as adjuncts to radiation therapy
IL83767A (en) * 1986-09-18 1992-11-15 American Home Prod Benzenesulfonamide derivatives,their preparation and pharmaceutical compositions containing them
US5391757A (en) * 1987-08-17 1995-02-21 American Cyanamid Company Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents
US5252539A (en) * 1987-08-17 1993-10-12 American Cyanamid Company Benzenesulfonyl carboxamide compounds intermediate compounds and method of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents
US5338883A (en) * 1987-08-17 1994-08-16 American Cyanamid Company Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents
US4992094A (en) * 1987-08-17 1991-02-12 American Cyanamid Company Phenylsulfonyl 2-imidazolin-5-one compounds
US4883914A (en) * 1987-08-17 1989-11-28 American Cyanamid Company Benzenesulfonyl carboxamide compounds useful as herbicidal agents
US5120854A (en) * 1987-08-17 1992-06-09 American Cyanamid Company Benzenesulfonyl carboxamide compounds and intermediate compounds
US4959501A (en) * 1987-09-04 1990-09-25 Ciba-Geigy Corporation Process for the preparation of 2-(2-chloroethoxy)-benzenesulfonamide
JP2556722B2 (ja) * 1988-02-18 1996-11-20 興和株式会社 新規なスルホンアミド化合物
JP2000504677A (ja) * 1996-02-09 2000-04-18 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５ｈｔ７レセプター・アンタゴニスト用のスルホンアミド誘導体
GB9803536D0 (en) * 1998-02-19 1998-04-15 Black James Foundation Histamine H,receptor ligands
US20100048713A1 (en) * 2006-01-06 2010-02-25 Aarhus Universitet Compounds acting on the serotonin transporter

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139381A (en) * 1957-02-07 1964-06-30 Merck & Co Inc Process of effecting diuresis with nitro disulfamylaniline compounds
DE1145182B (de) * 1957-06-17 1963-03-14 Du Pont Verfahren zur Herstellung von 4-Alkoxymetanilamiden und deren Salzen
US3060206A (en) * 1960-09-27 1962-10-23 Merck & Co Inc 2, 4-disulfamyl-5-alkoxy-aniline
US3580949A (en) * 1965-03-19 1971-05-25 Hoffmann La Roche N,n'-bis-(aminoalkyl)-benzyl-amines
US3840569A (en) * 1972-11-13 1974-10-08 Lilly Co Eli N1-aryloxy(arylthio)dinitro-sulfanilamides
CH590830A5 (2) * 1973-02-20 1977-08-31 Hoechst Ag

Also Published As

Publication number Publication date
US4132786A (en) 1979-01-02
AT358555B (de) 1980-09-25
ES448646A1 (es) 1977-07-01
FR2313918B1 (2) 1978-10-06
SE7606440L (sv) 1976-12-10
JPS60243060A (ja) 1985-12-03
GB1545628A (en) 1979-05-10
BE842753A (fr) 1976-12-09
SE430248B (sv) 1983-10-31
JPS6049630B2 (ja) 1985-11-02
DK146592B (da) 1983-11-14
DK252376A (da) 1976-12-10
NL7606172A (nl) 1976-12-13
JPS5231044A (en) 1977-03-09
CH616917A5 (2) 1980-04-30
DE2623447A1 (de) 1977-01-13
ATA401976A (de) 1980-02-15
FR2313918A1 (fr) 1977-01-07
DK146592C (da) 1984-06-12

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Legal Events

Date Code Title Description
MKEX Expiry