CA1204774A - Derives d'alkylbenzylidene ayant des prorpietes pharmacologiques - Google Patents

Derives d'alkylbenzylidene ayant des prorpietes pharmacologiques

Info

Publication number
CA1204774A
CA1204774A CA000442044A CA442044A CA1204774A CA 1204774 A CA1204774 A CA 1204774A CA 000442044 A CA000442044 A CA 000442044A CA 442044 A CA442044 A CA 442044A CA 1204774 A CA1204774 A CA 1204774A
Authority
CA
Canada
Prior art keywords
radical
general formula
hydroxy
chloro
alkaline earth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000442044A
Other languages
English (en)
Inventor
Jean-Pierre Kaplan
Bernard Raizon
Michel Peynot
Michel Mangane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of CA1204774A publication Critical patent/CA1204774A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000442044A 1982-11-29 1983-11-28 Derives d'alkylbenzylidene ayant des prorpietes pharmacologiques Expired CA1204774A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8219981A FR2536746A1 (fr) 1982-11-29 1982-11-29 Derives benzylideniques alkyles, leur preparation et leur application en therapeutique
FR8219981 1982-11-29

Publications (1)

Publication Number Publication Date
CA1204774A true CA1204774A (fr) 1986-05-20

Family

ID=9279618

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000442044A Expired CA1204774A (fr) 1982-11-29 1983-11-28 Derives d'alkylbenzylidene ayant des prorpietes pharmacologiques

Country Status (22)

Country Link
JP (1) JPS59116253A (fr)
AU (1) AU2174583A (fr)
BE (1) BE898323A (fr)
CA (1) CA1204774A (fr)
CH (1) CH656876A5 (fr)
DE (1) DE3343000A1 (fr)
DK (1) DK544283D0 (fr)
ES (1) ES527584A0 (fr)
FI (1) FI834339A7 (fr)
FR (1) FR2536746A1 (fr)
GB (1) GB2131024B (fr)
GR (1) GR81258B (fr)
HU (1) HU190636B (fr)
IL (1) IL70334A0 (fr)
IT (1) IT1167029B (fr)
LU (1) LU85106A1 (fr)
NL (1) NL8304070A (fr)
NO (1) NO834361L (fr)
NZ (1) NZ206409A (fr)
PT (1) PT77752B (fr)
SE (1) SE8305306L (fr)
ZA (1) ZA838862B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2577923B1 (fr) * 1985-02-26 1988-09-09 Synthelabo Diphenylazomethines carboxylees, leur preparation et leur application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319338A1 (fr) * 1975-08-01 1977-02-25 Synthelabo Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent
FR2516509B1 (fr) * 1981-11-18 1985-07-26 Synthelabo Derives benzylideniques, leur preparation et leur application en therapeutique
NL7901474A (nl) * 1978-02-27 1979-08-29 Synthelabo Werkwijze ter bereiding van een geneesmiddel dat actief is ten aanzien van het centrale zenuwstelsel, het aldus bereide geneesmiddel en werkwijze ter bereiding van de actieve benzylideen derivaat.
FR2422628A1 (fr) * 1978-04-14 1979-11-09 Synthelabo Esters benzylideniques et leur application en therapeutique

Also Published As

Publication number Publication date
FI834339L (fi) 1984-05-30
FR2536746A1 (fr) 1984-06-01
IL70334A0 (en) 1984-02-29
CH656876A5 (fr) 1986-07-31
FI834339A0 (fi) 1983-11-28
LU85106A1 (fr) 1985-07-17
FI834339A7 (fi) 1984-05-30
SE8305306L (sv) 1984-05-30
NL8304070A (nl) 1984-06-18
ES8406420A1 (es) 1984-08-01
GB2131024B (en) 1986-02-19
PT77752A (fr) 1983-12-01
GB8331714D0 (en) 1984-01-04
HU190636B (en) 1986-09-29
ZA838862B (en) 1984-07-25
JPS59116253A (ja) 1984-07-05
NO834361L (no) 1984-05-30
GR81258B (fr) 1984-12-11
FR2536746B1 (fr) 1985-03-08
BE898323A (fr) 1984-05-28
AU2174583A (en) 1984-06-07
SE8305306D0 (sv) 1983-09-29
GB2131024A (en) 1984-06-13
ES527584A0 (es) 1984-08-01
PT77752B (fr) 1986-06-02
DE3343000A1 (de) 1984-05-30
IT8323927A0 (it) 1983-11-28
IT1167029B (it) 1987-05-06
NZ206409A (en) 1986-07-11
DK544283D0 (da) 1983-11-28

Similar Documents

Publication Publication Date Title
EP0183191B1 (fr) Dérivés de thiénylthiazole
US3642785A (en) Indenyl-3-aliphatic amines
NO170883B (no) Fremgangsmaate for fremstilling av 2-amino-5-hydroksy-4-metylpyrimidin-derivater
US3984431A (en) Derivatives of pyrazole-5-acetic acid
IE47960B1 (en) Tetrazole derivatives
CA1127165A (fr) Procede d'obtention de dibenzothiepine
DE69411589T2 (de) Indol, indolin und chinolin derivate mit einer 5ht1d antagonistischen wirkung
DE3035086A1 (de) Cyclohexancarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende mittel
CA1144551A (fr) 4,5-diaryl-a-(polyfluoro-alkyl)1h-pyrrole- 2-methanamines, agents anti-inflammatoires
JPH0222059B2 (fr)
CA1204774A (fr) Derives d'alkylbenzylidene ayant des prorpietes pharmacologiques
US4500731A (en) Derivatives of 4-phenyl-4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and therapeutic uses for them
US4473583A (en) Compositions containing certain derivatives of 4-phenyl-4-oxobuten-2-oic acid and methods of treatment using them
FI81346C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara -/10-oxi-4h-benso/4,5/cyklohepta/1,2-b/ tiofen-4-yliden/karboxylsyraderivat.
US4116972A (en) Anti-inflammatory 1-oxo-isoindoline derivatives and processes for their preparation
US4555513A (en) 1,2 Dihydro- and 1,2,3,4-tetrahydro quinolylacetic acids and analgesic use thereof
CH574921A5 (en) Anti-inflammatory alpha-aminophenyl carboxylic acids
US4767767A (en) 2-pyrrolidinylethyl-2-(7-trifluoromethyl-4-quinolyl-aminobenzoate having analgesic, antipyretic and anti-inflammatory activities
US4420482A (en) 1,4-Bis(acetylsalicyloyloxy)piperizine derivatives
US4126625A (en) Certain 5-substituted-3-methyl-2-benzofuran acetic acids
US4189607A (en) Anilionotropone derivatives
US4243665A (en) 2-Heterocyclylalkyl-6-methoxy-naphthalenes
GB2027022A (en) Pyridoxine derivatives and their use
US3465002A (en) (succinimidoaryloxy)alkanoic acids,esters and amides thereof
US3631069A (en) Substituted phenethyl alcohols and their esters

Legal Events

Date Code Title Description
MKEX Expiry