CA1204962A - Pompe a sang et methode de production - Google Patents

Pompe a sang et methode de production

Info

Publication number: CA1204962A
Authority: CA; Canada
Prior art keywords: sac; blood; blood pump; pump according; polyurethane
Prior art date: 1980-11-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000401403A

Other languages

English (en)

Inventor

Yasushi Joh

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Zeon Corp

Original Assignee

Nippon Zeon Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-10

Filing date

1982-04-21

Publication date

1986-05-27

1980-11-10 Priority claimed from JP55157942A external-priority patent/JPS6022944B2/ja

1982-04-21 Application filed by Nippon Zeon Co Ltd filed Critical Nippon Zeon Co Ltd

1984-08-17 Priority to CA000461320A priority Critical patent/CA1200957A/fr

1984-08-17 Priority to CA000461319A priority patent/CA1191050A/fr

1986-05-27 Application granted granted Critical

1986-05-27 Publication of CA1204962A publication Critical patent/CA1204962A/fr

Status Expired legal-status Critical Current

Links

239000008280 blood Substances 0.000 title claims abstract description 134
210000004369 blood Anatomy 0.000 title claims abstract description 134
238000004519 manufacturing process Methods 0.000 title description 9
230000001105 regulatory effect Effects 0.000 claims abstract description 12
238000007599 discharging Methods 0.000 claims abstract description 8
239000012530 fluid Substances 0.000 claims abstract description 6
239000004814 polyurethane Substances 0.000 claims description 42
229920002635 polyurethane Polymers 0.000 claims description 39
239000004800 polyvinyl chloride Substances 0.000 claims description 18
229920000915 polyvinyl chloride Polymers 0.000 claims description 18
239000004205 dimethyl polysiloxane Substances 0.000 claims description 10
235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 10
229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 9
239000000463 material Substances 0.000 claims description 7
229920001577 copolymer Polymers 0.000 claims description 5
239000004721 Polyphenylene oxide Substances 0.000 claims description 4
229920000570 polyether Polymers 0.000 claims description 4
229920001400 block copolymer Polymers 0.000 claims description 3
239000000203 mixture Substances 0.000 claims description 3
238000010009 beating Methods 0.000 claims description 2
230000000875 corresponding effect Effects 0.000 claims 1
230000003247 decreasing effect Effects 0.000 claims 1
229920001944 Plastisol Polymers 0.000 description 20
239000004999 plastisol Substances 0.000 description 20
238000000034 method Methods 0.000 description 17
230000008569 process Effects 0.000 description 14
238000010438 heat treatment Methods 0.000 description 11
239000004014 plasticizer Substances 0.000 description 9
238000007598 dipping method Methods 0.000 description 8
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
230000006835 compression Effects 0.000 description 6
238000007906 compression Methods 0.000 description 6
125000005442 diisocyanate group Chemical group 0.000 description 6
MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 5
208000007536 Thrombosis Diseases 0.000 description 5
230000009471 action Effects 0.000 description 5
BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 5
238000010276 construction Methods 0.000 description 5
IRIAEXORFWYRCZ-UHFFFAOYSA-N Butylbenzyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCC1=CC=CC=C1 IRIAEXORFWYRCZ-UHFFFAOYSA-N 0.000 description 4
230000008602 contraction Effects 0.000 description 4
238000013461 design Methods 0.000 description 4
DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 4
230000000694 effects Effects 0.000 description 4
238000002474 experimental method Methods 0.000 description 4
-1 for example Substances 0.000 description 4
239000001993 wax Substances 0.000 description 4
230000008859 change Effects 0.000 description 3
239000003431 cross linking reagent Substances 0.000 description 3
229920001971 elastomer Polymers 0.000 description 3
239000000806 elastomer Substances 0.000 description 3
125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
229910052751 metal Inorganic materials 0.000 description 3
239000002184 metal Substances 0.000 description 3
239000012188 paraffin wax Substances 0.000 description 3
229920006264 polyurethane film Polymers 0.000 description 3
239000000243 solution Substances 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
MTZUIIAIAKMWLI-UHFFFAOYSA-N 1,2-diisocyanatobenzene Chemical compound O=C=NC1=CC=CC=C1N=C=O MTZUIIAIAKMWLI-UHFFFAOYSA-N 0.000 description 2
UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 description 2
QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 description 2
GOJCZVPJCKEBQV-UHFFFAOYSA-N Butyl phthalyl butylglycolate Chemical compound CCCCOC(=O)COC(=O)C1=CC=CC=C1C(=O)OCCCC GOJCZVPJCKEBQV-UHFFFAOYSA-N 0.000 description 2
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
238000007792 addition Methods 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
230000017531 blood circulation Effects 0.000 description 2
210000004204 blood vessel Anatomy 0.000 description 2
WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 description 2
239000000470 constituent Substances 0.000 description 2
238000004132 cross linking Methods 0.000 description 2
125000003827 glycol group Chemical group 0.000 description 2
RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 2
238000009413 insulation Methods 0.000 description 2
229920000642 polymer Polymers 0.000 description 2
229920005862 polyol Polymers 0.000 description 2
150000003077 polyols Chemical class 0.000 description 2
239000002904 solvent Substances 0.000 description 2
239000000758 substrate Substances 0.000 description 2
229920003002 synthetic resin Polymers 0.000 description 2
239000000057 synthetic resin Substances 0.000 description 2
DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 description 2
238000003466 welding Methods 0.000 description 2
ZXHZWRZAWJVPIC-UHFFFAOYSA-N 1,2-diisocyanatonaphthalene Chemical compound C1=CC=CC2=C(N=C=O)C(N=C=O)=CC=C21 ZXHZWRZAWJVPIC-UHFFFAOYSA-N 0.000 description 1
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
CBCKQZAAMUWICA-UHFFFAOYSA-N 1,4-phenylenediamine Chemical compound NC1=CC=C(N)C=C1 CBCKQZAAMUWICA-UHFFFAOYSA-N 0.000 description 1
SBJCUZQNHOLYMD-UHFFFAOYSA-N 1,5-Naphthalene diisocyanate Chemical compound C1=CC=C2C(N=C=O)=CC=CC2=C1N=C=O SBJCUZQNHOLYMD-UHFFFAOYSA-N 0.000 description 1
229940008841 1,6-hexamethylene diisocyanate Drugs 0.000 description 1
ICLCCFKUSALICQ-UHFFFAOYSA-N 1-isocyanato-4-(4-isocyanato-3-methylphenyl)-2-methylbenzene Chemical compound C1=C(N=C=O)C(C)=CC(C=2C=C(C)C(N=C=O)=CC=2)=C1 ICLCCFKUSALICQ-UHFFFAOYSA-N 0.000 description 1
RQBUVIFBALZGPC-UHFFFAOYSA-N 1-isocyanato-4-(4-isocyanatophenyl)benzene Chemical compound C1=CC(N=C=O)=CC=C1C1=CC=C(N=C=O)C=C1 RQBUVIFBALZGPC-UHFFFAOYSA-N 0.000 description 1
HUWXDEQWWKGHRV-UHFFFAOYSA-N 3,3'-Dichlorobenzidine Chemical compound C1=C(Cl)C(N)=CC=C1C1=CC=C(N)C(Cl)=C1 HUWXDEQWWKGHRV-UHFFFAOYSA-N 0.000 description 1
JRBJSXQPQWSCCF-UHFFFAOYSA-N 3,3'-Dimethoxybenzidine Chemical compound C1=C(N)C(OC)=CC(C=2C=C(OC)C(N)=CC=2)=C1 JRBJSXQPQWSCCF-UHFFFAOYSA-N 0.000 description 1
NUIURNJTPRWVAP-UHFFFAOYSA-N 3,3'-Dimethylbenzidine Chemical compound C1=C(N)C(C)=CC(C=2C=C(C)C(N)=CC=2)=C1 NUIURNJTPRWVAP-UHFFFAOYSA-N 0.000 description 1
YBRVSVVVWCFQMG-UHFFFAOYSA-N 4,4'-diaminodiphenylmethane Chemical compound C1=CC(N)=CC=C1CC1=CC=C(N)C=C1 YBRVSVVVWCFQMG-UHFFFAOYSA-N 0.000 description 1
IBOFVQJTBBUKMU-UHFFFAOYSA-N 4,4'-methylene-bis-(2-chloroaniline) Chemical compound C1=C(Cl)C(N)=CC=C1CC1=CC=C(N)C(Cl)=C1 IBOFVQJTBBUKMU-UHFFFAOYSA-N 0.000 description 1
239000004970 Chain extender Substances 0.000 description 1
206010018910 Haemolysis Diseases 0.000 description 1
239000005057 Hexamethylene diisocyanate Substances 0.000 description 1
KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 description 1
ALQSHHUCVQOPAS-UHFFFAOYSA-N Pentane-1,5-diol Chemical compound OCCCCCO ALQSHHUCVQOPAS-UHFFFAOYSA-N 0.000 description 1
229920000562 Poly(ethylene adipate) Polymers 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 1
IHBCFWWEZXPPLG-UHFFFAOYSA-N [Ca].[Zn] Chemical compound [Ca].[Zn] IHBCFWWEZXPPLG-UHFFFAOYSA-N 0.000 description 1
WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical group OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 description 1
239000003146 anticoagulant agent Substances 0.000 description 1
229940127219 anticoagulant drug Drugs 0.000 description 1
ZFMQKOWCDKKBIF-UHFFFAOYSA-N bis(3,5-difluorophenyl)phosphane Chemical compound FC1=CC(F)=CC(PC=2C=C(F)C=C(F)C=2)=C1 ZFMQKOWCDKKBIF-UHFFFAOYSA-N 0.000 description 1
230000023555 blood coagulation Effects 0.000 description 1
230000036772 blood pressure Effects 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
230000000747 cardiac effect Effects 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
HGAZMNJKRQFZKS-UHFFFAOYSA-N chloroethene;ethenyl acetate Chemical compound ClC=C.CC(=O)OC=C HGAZMNJKRQFZKS-UHFFFAOYSA-N 0.000 description 1
230000004087 circulation Effects 0.000 description 1
239000000701 coagulant Substances 0.000 description 1
239000002131 composite material Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000001723 curing Methods 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
238000011161 development Methods 0.000 description 1
150000004985 diamines Chemical class 0.000 description 1
SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 description 1
150000002009 diols Chemical class 0.000 description 1
KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
239000002612 dispersion medium Substances 0.000 description 1
230000007613 environmental effect Effects 0.000 description 1
239000003822 epoxy resin Substances 0.000 description 1
230000004907 flux Effects 0.000 description 1
230000005484 gravity Effects 0.000 description 1
238000013007 heat curing Methods 0.000 description 1
230000008588 hemolysis Effects 0.000 description 1
229920001519 homopolymer Polymers 0.000 description 1
238000003780 insertion Methods 0.000 description 1
230000037431 insertion Effects 0.000 description 1
WFKAJVHLWXSISD-UHFFFAOYSA-N isobutyramide Chemical compound CC(C)C(N)=O WFKAJVHLWXSISD-UHFFFAOYSA-N 0.000 description 1
239000007788 liquid Substances 0.000 description 1
230000007774 longterm Effects 0.000 description 1
QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
229910052753 mercury Inorganic materials 0.000 description 1
238000000465 moulding Methods 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
239000003921 oil Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
ZHZCYWWNFQUZOR-UHFFFAOYSA-N pent-4-en-2-ol Chemical group CC(O)CC=C ZHZCYWWNFQUZOR-UHFFFAOYSA-N 0.000 description 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
239000004417 polycarbonate Substances 0.000 description 1
229920000515 polycarbonate Polymers 0.000 description 1
229920000647 polyepoxide Polymers 0.000 description 1
229920000728 polyester Polymers 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
229920001451 polypropylene glycol Polymers 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000011084 recovery Methods 0.000 description 1
229920005989 resin Polymers 0.000 description 1
239000011347 resin Substances 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
238000004381 surface treatment Methods 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
238000012360 testing method Methods 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
230000007704 transition Effects 0.000 description 1
230000002861 ventricular Effects 0.000 description 1
125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1

Landscapes

External Artificial Organs (AREA)
Prostheses (AREA)

CA000401403A 1980-11-10 1982-04-21 Pompe a sang et methode de production Expired CA1204962A (fr)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
CA000461320A CA1200957A (fr)	1980-11-10	1984-08-17	Pompe a sang et methode de fabrication
CA000461319A CA1191050A (fr)	1980-11-10	1984-08-17	Pompe a sang et methode de fabrication

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP55157942A JPS6022944B2 (ja)	1980-11-10	1980-11-10	血液用ポンプ装置

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000461319A Division CA1191050A (fr)	1980-11-10	1984-08-17	Pompe a sang et methode de fabrication

Publications (1)

Publication Number	Publication Date
CA1204962A true CA1204962A (fr)	1986-05-27

Family

ID=15660830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000401403A Expired CA1204962A (fr)	1980-11-10	1982-04-21	Pompe a sang et methode de production

Country Status (1)

Country	Link
CA (1)	CA1204962A (fr)

1982
- 1982-04-21 CA CA000401403A patent/CA1204962A/fr not_active Expired

Legal Events

Date	Code	Title	Description
2003-05-27	MKEX	Expiry

Publication	Publication Date	Title
US4668459A (en)	1987-05-26	Blood pump and method of manufacturing the same
US6165215A (en)	2000-12-26	Method for producing heart valves
US5738627A (en)	1998-04-14	Bi-ventricular cardiac assist device
US4222127A (en)	1980-09-16	Blood pump and method of pumping blood
EP0170262A2 (fr)	1986-02-05	Soupape prostétique
JPH0999060A (ja)	1997-04-15	拍動型血液ポンプ
CA1204962A (fr)	1986-05-27	Pompe a sang et methode de production
JPS60242860A (ja)	1985-12-02	血液ポンプの成形方法
CA1191050A (fr)	1985-07-30	Pompe a sang et methode de fabrication
GB2255394A (en)	1992-11-04	Heart valve
JPH07178161A (ja)	1995-07-18	医療器具
Hayashi et al.	1985	Effects of implantation on the mechanical properties of the polyurethane diaphragm of left ventricular assist devices
JPS6359707B2 (fr)	1988-11-21
US5324464A (en)	1994-06-28	Method of making a blood pumping membrance for artificial ventricles
EP0313069A2 (fr)	1989-04-26	Procédé pour la fabrication d'objets sphériques
JPS59218159A (ja)	1984-12-08	サツク型血液ポンプ
JPS61255656A (ja)	1986-11-13	チユ−ブ内蔵型人工弁
JPH0317501B2 (fr)	1991-03-08
JPS622539B2 (fr)	1987-01-20
Hulsbergen et al.	1995	Elastomeric valves, a new design
JPH0380870A (ja)	1991-04-05	補助人工心臓
JPH0653159B2 (ja)	1994-07-20	生理学的血液移動が可能な人工心臓ポンプ
JPH02107269A (ja)	1990-04-19	逆止弁およびその製造方法
JPH0411225B2 (fr)	1992-02-27
JPS61252981A (ja)	1986-11-10	逆止め弁の製造方法